ATE464294T1 - Verfahren zur herstellung eines chinolincarbaldehyds - Google Patents
Verfahren zur herstellung eines chinolincarbaldehydsInfo
- Publication number
- ATE464294T1 ATE464294T1 AT02776535T AT02776535T ATE464294T1 AT E464294 T1 ATE464294 T1 AT E464294T1 AT 02776535 T AT02776535 T AT 02776535T AT 02776535 T AT02776535 T AT 02776535T AT E464294 T1 ATE464294 T1 AT E464294T1
- Authority
- AT
- Austria
- Prior art keywords
- producing
- quinoline
- carbaldehyde
- fluorophenyl
- cyclopropyl
- Prior art date
Links
- WRXZCLBKDXISQA-UHFFFAOYSA-N 2-chloro-7-methoxyquinoline-3-carbaldehyde Chemical compound C1=C(C=O)C(Cl)=NC2=CC(OC)=CC=C21 WRXZCLBKDXISQA-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- JAHBIRPTCXOGLB-UHFFFAOYSA-N 2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde Chemical compound C1=CC(F)=CC=C1C1=C(C=O)C(C2CC2)=NC2=CC=CC=C12 JAHBIRPTCXOGLB-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 abstract 1
- 229910001413 alkali metal ion Inorganic materials 0.000 abstract 1
- 229910001420 alkaline earth metal ion Inorganic materials 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003464 sulfur compounds Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001162986 | 2001-05-30 | ||
| JP2001208501 | 2001-07-09 | ||
| PCT/JP2002/004712 WO2002098859A1 (en) | 2001-05-30 | 2002-05-15 | Process for preparation of a quinolinecarbaldehyde |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE464294T1 true ATE464294T1 (de) | 2010-04-15 |
Family
ID=26615996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02776535T ATE464294T1 (de) | 2001-05-30 | 2002-05-15 | Verfahren zur herstellung eines chinolincarbaldehyds |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7193086B2 (https=) |
| EP (1) | EP1391455B1 (https=) |
| JP (1) | JP4318031B2 (https=) |
| KR (1) | KR100834326B1 (https=) |
| CN (1) | CN1261415C (https=) |
| AT (1) | ATE464294T1 (https=) |
| AU (1) | AU2002308986B2 (https=) |
| CA (1) | CA2448421C (https=) |
| DE (1) | DE60235978D1 (https=) |
| ES (1) | ES2342263T3 (https=) |
| TW (1) | TWI329636B (https=) |
| WO (1) | WO2002098859A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10216967A1 (de) * | 2002-04-16 | 2003-11-13 | Bayer Ag | Verfahren zur Herstellung spezieller aromatischer Aldehyde |
| CN101220021B (zh) * | 2007-01-12 | 2010-12-08 | 上海医药工业研究院 | 4-取代苯氧基喹啉类化合物及其中间体、制备方法和应用 |
| CN103204807B (zh) * | 2013-04-08 | 2015-12-23 | 黄河三角洲京博化工研究院有限公司 | 一种2-环丙基-4-（4-氟-苯基）-3-喹啉甲醛的合成方法 |
| CN111454215B (zh) * | 2020-04-28 | 2023-07-07 | 爱斯特（成都）生物制药股份有限公司 | 一种连续流臭氧氧化合成2-(4,6-二氯嘧啶-5-基)乙醛的工艺 |
| CN114522707B (zh) * | 2022-02-22 | 2023-07-21 | 中南大学 | 一种碱土金属碳酸盐负载纳米钌复合材料及其制备方法和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2569746B2 (ja) | 1987-08-20 | 1997-01-08 | 日産化学工業株式会社 | キノリン系メバロノラクトン類 |
| CA1336714C (en) | 1987-08-20 | 1995-08-15 | Yoshihiro Fujikawa | Quinoline type mevalonolactone inhibitors of cholesterol biosynthesis |
| JPH06239779A (ja) | 1993-02-19 | 1994-08-30 | Teijin Ltd | 光学活性シクロペンテンジオールの製造方法 |
| TW299317B (https=) * | 1993-03-12 | 1997-03-01 | Chemie Linz Gmbh | |
| JP3739432B2 (ja) * | 1994-02-25 | 2006-01-25 | ダイセル化学工業株式会社 | オゾン開裂反応 |
| JP3398525B2 (ja) | 1995-07-12 | 2003-04-21 | 旭化成株式会社 | 共重合体ラテックスの製造方法 |
-
2002
- 2002-05-15 US US10/479,226 patent/US7193086B2/en not_active Expired - Fee Related
- 2002-05-15 CA CA002448421A patent/CA2448421C/en not_active Expired - Fee Related
- 2002-05-15 DE DE60235978T patent/DE60235978D1/de not_active Expired - Lifetime
- 2002-05-15 CN CNB028107691A patent/CN1261415C/zh not_active Expired - Fee Related
- 2002-05-15 KR KR1020037015406A patent/KR100834326B1/ko not_active Expired - Fee Related
- 2002-05-15 EP EP02776535A patent/EP1391455B1/en not_active Expired - Lifetime
- 2002-05-15 AT AT02776535T patent/ATE464294T1/de not_active IP Right Cessation
- 2002-05-15 ES ES02776535T patent/ES2342263T3/es not_active Expired - Lifetime
- 2002-05-15 JP JP2003501983A patent/JP4318031B2/ja not_active Expired - Fee Related
- 2002-05-15 AU AU2002308986A patent/AU2002308986B2/en not_active Ceased
- 2002-05-15 WO PCT/JP2002/004712 patent/WO2002098859A1/ja not_active Ceased
- 2002-05-22 TW TW091110799A patent/TWI329636B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002098859A1 (en) | 2002-12-12 |
| EP1391455B1 (en) | 2010-04-14 |
| DE60235978D1 (de) | 2010-05-27 |
| EP1391455A4 (en) | 2005-04-06 |
| ES2342263T3 (es) | 2010-07-05 |
| JPWO2002098859A1 (ja) | 2004-09-16 |
| EP1391455A1 (en) | 2004-02-25 |
| US20040147750A1 (en) | 2004-07-29 |
| AU2002308986B2 (en) | 2007-05-31 |
| CN1261415C (zh) | 2006-06-28 |
| TWI329636B (https=) | 2010-09-01 |
| US7193086B2 (en) | 2007-03-20 |
| CA2448421A1 (en) | 2002-12-12 |
| KR20040030631A (ko) | 2004-04-09 |
| JP4318031B2 (ja) | 2009-08-19 |
| CN1512984A (zh) | 2004-07-14 |
| CA2448421C (en) | 2009-11-24 |
| KR100834326B1 (ko) | 2008-06-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |