MXPA05013981A - Resolucion de derivados de acido a- (fenoxi) fenilacetico. - Google Patents
Resolucion de derivados de acido a- (fenoxi) fenilacetico.Info
- Publication number
- MXPA05013981A MXPA05013981A MXPA05013981A MXPA05013981A MXPA05013981A MX PA05013981 A MXPA05013981 A MX PA05013981A MX PA05013981 A MXPA05013981 A MX PA05013981A MX PA05013981 A MXPA05013981 A MX PA05013981A MX PA05013981 A MXPA05013981 A MX PA05013981A
- Authority
- MX
- Mexico
- Prior art keywords
- phenoxy
- alpha
- phenylacetic acid
- resolution
- acid derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
La presente invencion proporciona un metodo para producir un compuesto de alfa - (fenoxi) fenilacetico enriquecido enantiomericamente de formula (?): a partir de su mezcla enantiomerica, en donde R1 es alquilo o haloalquilo y X es haluro.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60018903A | 2003-06-20 | 2003-06-20 | |
US10/656,567 US7199259B2 (en) | 2003-06-20 | 2003-09-04 | Resolution of α-(phenoxy)phenylacetic acid derivatives |
PCT/US2004/019616 WO2004112774A1 (en) | 2003-06-20 | 2004-06-18 | RESOLUTION OF α-(PHENOXY)PHENYLACETIC ACID DERIVATIVES |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA05013981A true MXPA05013981A (es) | 2006-03-02 |
Family
ID=33544772
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA05013981A MXPA05013981A (es) | 2003-06-20 | 2004-06-18 | Resolucion de derivados de acido a- (fenoxi) fenilacetico. |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1635809A4 (es) |
KR (1) | KR101073742B1 (es) |
CA (1) | CA2529774C (es) |
IL (1) | IL172663A0 (es) |
MX (1) | MXPA05013981A (es) |
RS (1) | RS20050937A (es) |
WO (1) | WO2004112774A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7576131B2 (en) | 1999-06-04 | 2009-08-18 | Metabolex, Inc. | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia |
US6262118B1 (en) | 1999-06-04 | 2001-07-17 | Metabolex, Inc. | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia |
US7199259B2 (en) | 2003-06-20 | 2007-04-03 | Metabolex, Inc. | Resolution of α-(phenoxy)phenylacetic acid derivatives |
US8288438B2 (en) | 2005-03-21 | 2012-10-16 | Metabolex, Inc. | Methods for avoiding edema in the treatment or prevention of PPARγ-responsive diseases, including cancer |
KR100678287B1 (ko) * | 2005-06-23 | 2007-02-02 | 한미약품 주식회사 | 클로피도그렐의 제조방법 및 이에 사용되는 중간체 |
US7714131B2 (en) | 2005-09-23 | 2010-05-11 | Metabolex, Inc. | Process for the stereoselective preparation of (−)-halofenate and derivatives thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL6712585A (es) * | 1966-10-03 | 1968-04-04 | ||
US3517050A (en) * | 1966-10-03 | 1970-06-23 | Merck & Co Inc | Ester and amide derivative of (3-trifluoromethylphenoxy) (4 - halophenyl)acetic acid |
US6624194B1 (en) * | 1999-06-04 | 2003-09-23 | Metabolex, Inc. | Use of (−) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia |
US6262118B1 (en) * | 1999-06-04 | 2001-07-17 | Metabolex, Inc. | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia |
-
2004
- 2004-06-18 WO PCT/US2004/019616 patent/WO2004112774A1/en active Application Filing
- 2004-06-18 RS YUP-2005/0937A patent/RS20050937A/sr unknown
- 2004-06-18 MX MXPA05013981A patent/MXPA05013981A/es active IP Right Grant
- 2004-06-18 CA CA2529774A patent/CA2529774C/en not_active Expired - Fee Related
- 2004-06-18 EP EP04755657A patent/EP1635809A4/en not_active Withdrawn
-
2005
- 2005-12-18 IL IL172663A patent/IL172663A0/en unknown
- 2005-12-20 KR KR1020057024492A patent/KR101073742B1/ko active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
IL172663A0 (en) | 2006-04-10 |
CA2529774A1 (en) | 2004-12-29 |
EP1635809A4 (en) | 2006-09-27 |
KR101073742B1 (ko) | 2011-10-13 |
CA2529774C (en) | 2014-05-27 |
WO2004112774A1 (en) | 2004-12-29 |
RS20050937A (en) | 2008-04-04 |
EP1635809A1 (en) | 2006-03-22 |
KR20060030048A (ko) | 2006-04-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration | ||
HC | Change of company name or juridical status |