BR9813796A - "processo para a produção de certos compostos de ácido benzóico" - Google Patents

"processo para a produção de certos compostos de ácido benzóico"

Info

Publication number
BR9813796A
BR9813796A BR9813796-4A BR9813796A BR9813796A BR 9813796 A BR9813796 A BR 9813796A BR 9813796 A BR9813796 A BR 9813796A BR 9813796 A BR9813796 A BR 9813796A
Authority
BR
Brazil
Prior art keywords
difluoro
benzoic acid
treating
bromo
production
Prior art date
Application number
BR9813796-4A
Other languages
English (en)
Inventor
Benoit Ledoussal
Xiaomin Sharon Zheng
Ji-In Kim Almstead
Jeffrey Lyle Gray
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of BR9813796A publication Critical patent/BR9813796A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/08—Preparation of nitro compounds by substitution of hydrogen atoms by nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

Patente de Invenção: <B>"PROCESSO PARA A PRODUçãO DE CERTOS COMPOSTOS DE áCIDO BENZóICO"<D>. A presente invenção envolve processos para a produção de ácido 2,4-diflúor-3-Q1-benzóico, em que Q1 é derivada de um reagente eletrofílico, compreendendo as etapas de: (a) tratamento de 1-bromo-2,4-difluorobenzeno: com uma base não-nucleofílica forte: então tratamento com um reagente eletrofílico que provê Q1, ou uma porção funcional que é então transformada em Q1, produção de 1-bromo-2,4-diflúor-3-Q1-benzeno: (b) tratamento do 1-bromo-2,4-diflúor-3-Q1-benzeno com um reagente alcalino ou de metal alcalino-terroso ou organometálico; então tratamento com dióxido de carbono, ou com um agente de formulação seguido por oxidação, para produzir ácido 2,4-diflúor-3-Q1-benzóico. A presente invenção também envolve etapas adicionais opcionais para ulteriormente modificar Q1 ou para substituir um não hidrogênio na posição 5, na posição 6 ou em ambas, do anel fenila do ácido 2,4-diflúor-3-Q1-benzóico.
BR9813796-4A 1998-01-09 1998-12-28 "processo para a produção de certos compostos de ácido benzóico" BR9813796A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7086698P 1998-01-09 1998-01-09
PCT/IB1998/002116 WO1999035117A1 (en) 1998-01-09 1998-12-28 Process for making certain benzoic acid compounds

Publications (1)

Publication Number Publication Date
BR9813796A true BR9813796A (pt) 2000-10-03

Family

ID=22097850

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9813796-4A BR9813796A (pt) 1998-01-09 1998-12-28 "processo para a produção de certos compostos de ácido benzóico"

Country Status (14)

Country Link
US (1) US6348624B1 (pt)
EP (1) EP1045823B1 (pt)
JP (1) JP2002500210A (pt)
KR (1) KR20010034017A (pt)
CN (1) CN1284939A (pt)
AT (1) ATE308502T1 (pt)
AU (1) AU753247B2 (pt)
BR (1) BR9813796A (pt)
CA (1) CA2318489A1 (pt)
DE (1) DE69832199T2 (pt)
DK (1) DK1045823T3 (pt)
IL (2) IL137216A0 (pt)
NZ (1) NZ505639A (pt)
WO (1) WO1999035117A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10341534A1 (de) * 2003-09-09 2005-03-31 Bayer Chemicals Ag Difluoralkylaromaten
CN102731382B (zh) * 2006-01-13 2015-09-02 美国陶氏益农公司 6-(多取代芳基)-4-氨基吡啶甲酸酯及其作为除草剂的用途
US8658183B2 (en) 2007-08-09 2014-02-25 Taigen Biotechnology Company, Ltd. Antimicrobial parenteral formulation
CN102056883B (zh) 2008-06-06 2014-11-12 弗·哈夫曼-拉罗切有限公司 用于制备卤代苯甲酸衍生物的方法
EP2303271B1 (en) 2008-07-01 2018-11-07 Taigen Biotechnology Co., Ltd. Treatment of antibiotic-resistant bacteria infection
CN105712876A (zh) * 2014-12-01 2016-06-29 王志训 一种酯衍生物的工业生产方法
CN105646180A (zh) * 2016-03-01 2016-06-08 苏州艾缇克药物化学有限公司 一种医药中间体2，4-二氟苯甲酸的合成方法
CN105967974B (zh) * 2016-05-06 2018-08-31 蚌埠中实化学技术有限公司 一种2-甲基-3,4,5-三氟溴苯的制备方法
CN106365978B (zh) * 2016-08-31 2019-01-11 绍兴上虞华伦化工有限公司 一种2,3-二氟-6-甲氧基苯甲酸的制备方法
CN112473737A (zh) * 2020-09-25 2021-03-12 盐城工学院 一种Ag@MOF材料、其制备方法及应用
CN115073282A (zh) * 2022-06-08 2022-09-20 都创(重庆)医药科技有限公司 一种基于微通道连续流技术快速制备3-溴-2,4-二氟苯甲酸的方法

Also Published As

Publication number Publication date
DE69832199D1 (de) 2005-12-08
DE69832199T2 (de) 2006-08-03
IL137216A0 (en) 2001-07-24
NZ505639A (en) 2003-08-29
JP2002500210A (ja) 2002-01-08
IL137216A (en) 2006-12-10
CA2318489A1 (en) 1999-07-15
CN1284939A (zh) 2001-02-21
WO1999035117A1 (en) 1999-07-15
AU753247B2 (en) 2002-10-10
EP1045823A1 (en) 2000-10-25
EP1045823B1 (en) 2005-11-02
AU1502899A (en) 1999-07-26
ATE308502T1 (de) 2005-11-15
US6348624B1 (en) 2002-02-19
DK1045823T3 (da) 2006-02-13
KR20010034017A (ko) 2001-04-25

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO DE PATENTE DE ACORDO COM ART. 8O DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.