ATE463478T1 - Diaryletherderivat, dessen additionssalz und immunosuppressivum - Google Patents
Diaryletherderivat, dessen additionssalz und immunosuppressivumInfo
- Publication number
- ATE463478T1 ATE463478T1 AT02768056T AT02768056T ATE463478T1 AT E463478 T1 ATE463478 T1 AT E463478T1 AT 02768056 T AT02768056 T AT 02768056T AT 02768056 T AT02768056 T AT 02768056T AT E463478 T1 ATE463478 T1 AT E463478T1
- Authority
- AT
- Austria
- Prior art keywords
- immunosuppressant
- addition salt
- diaryl ether
- ether derivative
- diaryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/64—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Otolaryngology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Transplantation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Cephalosporin Compounds (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001297400 | 2001-09-27 | ||
JP2002216191 | 2002-07-25 | ||
PCT/JP2002/009864 WO2003029184A1 (fr) | 2001-09-27 | 2002-09-25 | Derive d'ether de diaryle, son sel d'addition et son immunosuppresseur |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE463478T1 true ATE463478T1 (de) | 2010-04-15 |
Family
ID=26623110
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02768056T ATE463478T1 (de) | 2001-09-27 | 2002-09-25 | Diaryletherderivat, dessen additionssalz und immunosuppressivum |
Country Status (7)
Country | Link |
---|---|
US (1) | US6963012B2 (fr) |
EP (1) | EP1431275B1 (fr) |
JP (1) | JP4152884B2 (fr) |
AT (1) | ATE463478T1 (fr) |
CA (1) | CA2460640C (fr) |
DE (1) | DE60235900D1 (fr) |
WO (1) | WO2003029184A1 (fr) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA04002679A (es) * | 2001-09-27 | 2004-07-30 | Kyorin Seiyaku Kk | Derivados de sulfuro de diarilo, sales de los mismos y agentes inmunosupresores que utilizan los mismos. |
BR0306811A (pt) * | 2002-01-11 | 2004-10-26 | Sankyo Co | Composto, éster farmacologicamente aceitável do mesmo, composição farmacêutica e métodos para prevenção ou tratamento de doenças autoimunes, da artrite reumatóide e da rejeição causada pelo transplante de vários órgãos em um mamìfero |
KR20120125398A (ko) | 2002-05-16 | 2012-11-14 | 노파르티스 아게 | 암에서 edg 수용체 결합제의 용도 |
CA2498944C (fr) * | 2002-09-19 | 2011-05-17 | Yasushi Kohno | Derives d'aminoalcool, sels connexes et agents immunosuppresseurs |
KR20080103117A (ko) | 2002-09-24 | 2008-11-26 | 노파르티스 아게 | 탈수초성 장애의 치료에 있어서의 스핑고신-1-포스페이트 수용체 아고니스트 |
HUE028247T2 (en) | 2003-04-08 | 2016-12-28 | Novartis Ag | A solid oral composition comprising S1P receptor agonist and sugar alcohol |
ES2383298T3 (es) * | 2003-04-30 | 2012-06-20 | Novartis Ag | Derivados del amino-propanol como moduladores del receptor esfingosina-1-fosfato |
GB0320638D0 (en) | 2003-09-03 | 2003-10-01 | Novartis Ag | Organic compounds |
GB0324210D0 (en) | 2003-10-15 | 2003-11-19 | Novartis Ag | Organic compounds |
GB0329498D0 (en) * | 2003-12-19 | 2004-01-28 | Novartis Ag | Organic compounds |
TW200526548A (en) * | 2003-12-25 | 2005-08-16 | Sankyo Co | Ether derivatives |
GB0500020D0 (en) | 2005-01-04 | 2005-02-09 | Novartis Ag | Organic compounds |
KR20110136901A (ko) * | 2004-02-24 | 2011-12-21 | 상꾜 가부시키가이샤 | 아미노 알코올 화합물 |
EP2363149A1 (fr) | 2004-05-03 | 2011-09-07 | Novartis AG | Combinaisons comportant un agoniste de récepteur S1P et inhibiteur de kinase JAK3 |
PL1772145T3 (pl) * | 2004-07-16 | 2011-08-31 | Kyorin Seiyaku Kk | Sposób skutecznego stosowania leku i sposób dotyczący zapobiegania efektom ubocznym |
TW200611687A (en) * | 2004-07-29 | 2006-04-16 | Sankyo Co | Pharmaceutical compositions used for immunosuppressant |
AU2005266449B2 (en) | 2004-07-30 | 2009-10-08 | Novartis Ag | Compound formulations of 2-amino-1,3-propanediol compounds |
KR101181090B1 (ko) | 2004-10-12 | 2012-09-07 | 교린 세이야꾸 가부시키 가이샤 | 2-아미노-2-[2-[4-(3-벤질옥시페닐티오)-2-클로로페닐]에틸]-1,3-프로판디올 염산염 또는 그 수화물의 제조방법 및 그 제조 중간체 |
JP2008521827A (ja) | 2004-11-29 | 2008-06-26 | ノバルティス アクチエンゲゼルシャフト | S1p受容体アゴニストの投与レジメン |
GB0504544D0 (en) | 2005-03-04 | 2005-04-13 | Novartis Ag | Organic compounds |
TWI418350B (zh) * | 2005-06-24 | 2013-12-11 | Sankyo Co | 含有ppar調節劑之醫藥組成物的用途 |
AR057455A1 (es) * | 2005-07-22 | 2007-12-05 | Merck & Co Inc | Inhibidores de la transcriptasa reversa de vih y composicion farmaceutica |
KR101476591B1 (ko) * | 2005-09-09 | 2014-12-24 | 노파르티스 아게 | 자가면역성 질환의 치료 |
PT1932522E (pt) | 2005-10-07 | 2012-06-26 | Kyorin Seiyaku Kk | Agente terapêutico para doenças do fígado contendo, como princípio activo, um derivado de 2- amino-1,3-propanodiol |
TWI389683B (zh) * | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
ES2543840T3 (es) | 2006-04-11 | 2015-08-24 | Novartis Ag | Inhibidores espirocíclicos del VHC/VIH y sus usos |
WO2007126042A1 (fr) | 2006-04-28 | 2007-11-08 | Mitsubishi Tanabe Pharma Corporation | Compose 2-aminobutanol et son utilisation a but medical |
TW200815600A (en) | 2006-08-04 | 2008-04-01 | Daiichi Sankyo Co Ltd | An enzyme for phosphorizing a medicine |
NZ574011A (en) | 2006-08-08 | 2011-10-28 | Kyorin Seiyaku Kk | Aminophosphoric acid ester derivative and s1p receptor modulator containing the same as active ingredient |
MY146775A (en) | 2006-08-08 | 2012-09-28 | Kyorin Seiyaku Kk | Amino alcohol derivative and immunosuppressive agent having same as an active ingredient |
CA2690686C (fr) | 2007-06-14 | 2013-08-06 | Mitsubishi Tanabe Pharma Corporation | Compose amine et son utilisation pharmaceutique |
WO2009048993A2 (fr) | 2007-10-12 | 2009-04-16 | Novartis Ag | Compositions comprenant des modulateurs du récepteur de sphingosine 1-phosphate (s1p) |
US7816435B2 (en) | 2007-10-31 | 2010-10-19 | Momentive Performance Materials Inc. | Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom |
TW200946105A (en) | 2008-02-07 | 2009-11-16 | Kyorin Seiyaku Kk | Therapeutic agent or preventive agent for inflammatory bowel disease containing amino alcohol derivative as active ingredient |
WO2009115954A1 (fr) | 2008-03-17 | 2009-09-24 | Actelion Pharmaceuticals Ltd | Régime de dosage pour un agoniste sélectif du récepteur s1p<sb>1</sb> |
CN103396346A (zh) * | 2008-05-19 | 2013-11-20 | 杏林制药株式会社 | 光学活性氨基醇衍生物的制备方法 |
RU2505288C2 (ru) | 2008-05-20 | 2014-01-27 | Киорин Фармасьютикал Ко., Лтд. | Средства поддержания индуцированной ремиссии |
GB0901835D0 (en) | 2009-02-04 | 2009-03-11 | Syngenta Ltd | Novel herbicides |
GB0901834D0 (en) | 2009-02-04 | 2009-03-11 | Syngenta Ltd | Novel herbicides |
US8512690B2 (en) | 2009-04-10 | 2013-08-20 | Novartis Ag | Derivatised proline containing peptide compounds as protease inhibitors |
US20110182850A1 (en) | 2009-04-10 | 2011-07-28 | Trixi Brandl | Organic compounds and their uses |
PT2452944E (pt) | 2009-07-09 | 2014-10-13 | Kyorin Seiyaku Kk | Derivados de sulfureto de difenilo e medicamentos que os contêm como ingredientes activos |
KR101148098B1 (ko) | 2010-04-30 | 2012-05-22 | 한국화학연구원 | 1-[4-(4-니트로-페녹시)-페닐]-프로판-1-온을 유효성분으로 함유하는 톡소포자충 및 콕시디움에 기인한 질환의 예방 및 치료용 조성물 |
BR112012028190A2 (pt) * | 2010-05-06 | 2016-08-02 | Novartis Ag | tratamento de doenças autoimunes |
CN102917698A (zh) | 2010-05-06 | 2013-02-06 | 诺瓦提斯公司 | 二芳基硫醚衍生物的给药方案 |
BR112013008510A2 (pt) | 2010-10-08 | 2016-07-05 | Novartis Ag | vitamina e formulações de inibidores de sulfamida ns3 |
TWI519539B (zh) | 2010-12-21 | 2016-02-01 | Kyorin Seiyaku Kk | Diphenyl sulfide derivatives and pharmaceuticals as an active ingredient thereof |
CN102863345A (zh) * | 2011-07-06 | 2013-01-09 | 中国医学科学院药物研究所 | 胺基丙二醇类衍生物、其制备方法和其药物组合物与用途 |
HUE027461T2 (en) | 2011-07-13 | 2016-09-28 | Basf Agro Bv | Fungicide substituted 2- [2-haloalkyl-4- (phenoxyphenyl) -1- [1,2,4] triazol-1-yl-ethanol compounds |
US9173402B2 (en) | 2011-07-15 | 2015-11-03 | Basf Se | Fungicidal alkyl-substituted 2[2-chloro-4-(4-chioro-phenoxy)-phenyl]-1[1,2,4]triazol-1-yl-ethanol compounds |
US9137996B2 (en) | 2011-07-15 | 2015-09-22 | Basf Se | Fungicidal alkyl- and aryl-substituted 2[-2-chloro-4-(dihalo-phenoxy)-phenyl]-1-[1,2,4]triazol-1-yl-ethanol compounds |
KR20140054234A (ko) | 2011-08-15 | 2014-05-08 | 바스프 에스이 | 살진균 치환된 1-{2-[2-할로-4-(4-할로겐-페녹시)-페닐]-2-알콕시-2-알키닐/알케닐-에틸}-1h-[1,2,4]트리아졸 화합물 |
WO2013024082A1 (fr) | 2011-08-15 | 2013-02-21 | Basf Se | Composés de 1-{2-cyclyloxy-2-[2-halogéno-4-(4-halogéno-phénoxy)-phényl]-éthyl}-1h-[1,2,4]triazole substitués fongicides |
UY34259A (es) | 2011-08-15 | 2013-02-28 | Basf Se | Compuestos fungicidas de 1-{2-[2-halo-4-(4-halogen-fenoxi)-fenil]-2-alcoxi-3-metil-butil}-1h-[1,2,4]triazol sustituidos |
EP2842937B1 (fr) | 2012-04-23 | 2018-01-17 | Mitsubishi Tanabe Pharma Corporation | Composé amine et son utilisation à des fins médicales |
EA030875B1 (ru) | 2012-12-20 | 2018-10-31 | Басф Агро Б.В. | Композиции, содержащие триазольное соединение |
ES2742288T3 (es) | 2013-01-09 | 2020-02-13 | Basf Agro Bv | Proceso para la preparación de oxiranos y triazoles sustituidos |
CA2916777A1 (fr) | 2013-07-08 | 2015-01-15 | BASF Agro B.V. | Compositions comprenant un compose triazole et un biopesticide |
CN104844486B (zh) * | 2014-02-17 | 2018-10-30 | 中国医学科学院药物研究所 | 胺基丙二醇类衍生物、其制备方法和其药物组合物与用途 |
CN106793776A (zh) | 2014-06-25 | 2017-05-31 | 巴斯夫农业公司 | 农药组合物 |
UA120628C2 (uk) | 2014-11-07 | 2020-01-10 | Басф Се | Пестицидні суміші |
US11241012B2 (en) | 2016-03-16 | 2022-02-08 | Basf Se | Use of tetrazolinones for combating resistant phytopathogenic fungi on soybean |
US10905122B2 (en) | 2016-03-16 | 2021-02-02 | Basf Se | Use of tetrazolinones for combating resistant phytopathogenic fungi on cereals |
US11425909B2 (en) | 2016-03-16 | 2022-08-30 | Basf Se | Use of tetrazolinones for combating resistant phytopathogenic fungi on fruits |
US20210283073A1 (en) | 2018-07-27 | 2021-09-16 | Priothera Limited | Agent for inhibiting recurrence of hematological malignancy in patients who have undergone hematopoietic stem cell transplantation |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR0155015B1 (ko) * | 1992-10-21 | 1998-12-01 | 고우야 마사시 | 2-아미노-1,3-프로판디올 화합물 및 면역 억제제 |
PT778263E (pt) * | 1994-08-22 | 2002-06-28 | Mitsubishi Pharma Corp | Composto de benzeno e sua utilizacao farmaceutica |
ATE298740T1 (de) | 1997-04-04 | 2005-07-15 | Mitsubishi Pharma Corp | 2-aminopropan-1,3-diol-verbindungen, ihre medizinische anwendung und zwischenprodukte zu ihrer synthese |
-
2002
- 2002-09-25 JP JP2003532439A patent/JP4152884B2/ja not_active Expired - Fee Related
- 2002-09-25 DE DE60235900T patent/DE60235900D1/de not_active Expired - Lifetime
- 2002-09-25 EP EP02768056A patent/EP1431275B1/fr not_active Expired - Lifetime
- 2002-09-25 AT AT02768056T patent/ATE463478T1/de not_active IP Right Cessation
- 2002-09-25 CA CA2460640A patent/CA2460640C/fr not_active Expired - Fee Related
- 2002-09-25 WO PCT/JP2002/009864 patent/WO2003029184A1/fr active Application Filing
- 2002-09-25 US US10/490,345 patent/US6963012B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6963012B2 (en) | 2005-11-08 |
WO2003029184A1 (fr) | 2003-04-10 |
EP1431275B1 (fr) | 2010-04-07 |
DE60235900D1 (de) | 2010-05-20 |
US20040242654A1 (en) | 2004-12-02 |
EP1431275A1 (fr) | 2004-06-23 |
JPWO2003029184A1 (ja) | 2005-01-13 |
EP1431275A4 (fr) | 2006-05-31 |
CA2460640A1 (fr) | 2003-04-10 |
CA2460640C (fr) | 2011-03-29 |
JP4152884B2 (ja) | 2008-09-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |