ATE463478T1 - Diaryletherderivat, dessen additionssalz und immunosuppressivum - Google Patents

Diaryletherderivat, dessen additionssalz und immunosuppressivum

Info

Publication number
ATE463478T1
ATE463478T1 AT02768056T AT02768056T ATE463478T1 AT E463478 T1 ATE463478 T1 AT E463478T1 AT 02768056 T AT02768056 T AT 02768056T AT 02768056 T AT02768056 T AT 02768056T AT E463478 T1 ATE463478 T1 AT E463478T1
Authority
AT
Austria
Prior art keywords
immunosuppressant
addition salt
diaryl ether
ether derivative
diaryl
Prior art date
Application number
AT02768056T
Other languages
English (en)
Inventor
Yasushi Kohno
Naoki Ando
Takahiro Tanase
Kazuhiko Kuriyama
Satoru Iwanami
Shinji Kudou
Original Assignee
Kyorin Seiyaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Seiyaku Kk filed Critical Kyorin Seiyaku Kk
Application granted granted Critical
Publication of ATE463478T1 publication Critical patent/ATE463478T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/64Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
AT02768056T 2001-09-27 2002-09-25 Diaryletherderivat, dessen additionssalz und immunosuppressivum ATE463478T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001297400 2001-09-27
JP2002216191 2002-07-25
PCT/JP2002/009864 WO2003029184A1 (fr) 2001-09-27 2002-09-25 Derive d'ether de diaryle, son sel d'addition et son immunosuppresseur

Publications (1)

Publication Number Publication Date
ATE463478T1 true ATE463478T1 (de) 2010-04-15

Family

ID=26623110

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02768056T ATE463478T1 (de) 2001-09-27 2002-09-25 Diaryletherderivat, dessen additionssalz und immunosuppressivum

Country Status (7)

Country Link
US (1) US6963012B2 (de)
EP (1) EP1431275B1 (de)
JP (1) JP4152884B2 (de)
AT (1) ATE463478T1 (de)
CA (1) CA2460640C (de)
DE (1) DE60235900D1 (de)
WO (1) WO2003029184A1 (de)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2461212C (en) * 2001-09-27 2010-08-17 Kyorin Pharmaceutical Co., Ltd. Diaryl sulfide derivatives, salts thereof and immunosuppressive agents using the same
DK1471054T3 (da) * 2002-01-11 2009-11-09 Daiichi Sankyo Co Ltd Aminoalkohol-derivat eller phosphonsyre-derivat og medicinsk sammensætning, der indeholder disse
EP1944026B1 (de) 2002-05-16 2013-06-26 Novartis AG Verwendung von EDG-Rezeptorbindemitteln bei Krebs
EP2617711A1 (de) 2002-09-19 2013-07-24 Kyorin Pharmaceutical Co., Ltd. Aminoalkoholderivate, Salze davon und Immunsuppressiva
PL375053A1 (en) 2002-09-24 2005-11-14 Novartis Ag Sphingosine-1-phosphate receptor agonists in the treatment of demyelinating disorders
PE20131352A1 (es) 2003-04-08 2013-11-14 Novartis Ag Composicion farmaceutica que contiene un agonista del receptor s1p y un alcohol de azucar
EP1622860B1 (de) * 2003-04-30 2012-02-29 Novartis AG Aminopropanol-derivate als modulatoren des sphingosin-1-phosphat-rezeptors
GB0320638D0 (en) 2003-09-03 2003-10-01 Novartis Ag Organic compounds
GB0324210D0 (en) * 2003-10-15 2003-11-19 Novartis Ag Organic compounds
GB0329498D0 (en) 2003-12-19 2004-01-28 Novartis Ag Organic compounds
TW200526548A (en) * 2003-12-25 2005-08-16 Sankyo Co Ether derivatives
GB0500020D0 (en) 2005-01-04 2005-02-09 Novartis Ag Organic compounds
TWI355934B (en) * 2004-02-24 2012-01-11 Sankyo Co Pharmaceutical composition for treatment or prophy
EP2363149A1 (de) 2004-05-03 2011-09-07 Novartis AG Kombinationen mit einem S1P-Rezeptoragonist und einem JAK3-Kinaseinhibitor
DK1772145T3 (da) * 2004-07-16 2011-05-30 Kyorin Seiyaku Kk Fremgangsmåde til effektiv anvendelse af medicin og fremgangsmåde til forebyggelse af bivirkninger
TW200611687A (en) * 2004-07-29 2006-04-16 Sankyo Co Pharmaceutical compositions used for immunosuppressant
CA2574664C (en) 2004-07-30 2013-01-15 Novartis Ag Compound formulations of 2-amino-1,3-propanediol compounds
ES2563034T3 (es) 2004-10-12 2016-03-10 Kyorin Pharmaceutical Co., Ltd. Procedimiento para producir hidrocloruro de 2-amino-2-[2-[4-(3-benciloxifeniltio)-2-clorofenil]etil]-1,3-propanodiol e hidratos del mismo, e intermedios para la producción de los mismos
KR20140095109A (ko) 2004-11-29 2014-07-31 노파르티스 아게 S1p 수용체 효능제의 투여 용법
GB0504544D0 (en) 2005-03-04 2005-04-13 Novartis Ag Organic compounds
TWI418350B (zh) * 2005-06-24 2013-12-11 Sankyo Co 含有ppar調節劑之醫藥組成物的用途
AR057455A1 (es) * 2005-07-22 2007-12-05 Merck & Co Inc Inhibidores de la transcriptasa reversa de vih y composicion farmaceutica
PL1926483T3 (pl) * 2005-09-09 2011-05-31 Novartis Ag Leczenie chorób autoimmunologicznych
BRPI0617077A2 (pt) * 2005-10-07 2015-01-06 Kyorin Seiyaku Kk Agente terapêutico para tratamento de doenças do fígado contendo 2-amina-1, 3-propanediol derivativo como ingrediente ativo, e método para tratamento de doenças do fígado
TWI389683B (zh) * 2006-02-06 2013-03-21 Kyorin Seiyaku Kk A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient
MX2008013119A (es) 2006-04-11 2008-10-21 Novartis Ag Inhibidores de hcv/vih y sus usos.
ES2491224T3 (es) 2006-04-28 2014-09-05 Mitsubishi Tanabe Pharma Corporation Compuesto de 2-aminobutanol y su uso para fines médicos
TW200815600A (en) 2006-08-04 2008-04-01 Daiichi Sankyo Co Ltd An enzyme for phosphorizing a medicine
RS53080B (en) 2006-08-08 2014-06-30 Kyorin Pharmaceutical Co. Ltd. AMINOPHOSPHORIC ACID ETHAR DERIVATIVE AND S1P RECEPTOR MODULATOR CONTAINING THE SAME AS THE ACTIVE INGREDIENT
KR20090041424A (ko) * 2006-08-08 2009-04-28 교린 세이야꾸 가부시키 가이샤 아미노알코올 유도체 및 그것들을 유효성분으로 하는 면역 억제제
EP2168944B1 (de) * 2007-06-14 2016-05-11 Mitsubishi Tanabe Pharma Corporation Aminverbindung und ihre pharmazeutische verwendung
EP3733162A1 (de) 2007-10-12 2020-11-04 Novartis AG Zusammensetzung mit sphingosin-1-phosphat (s1p)-rezeptormodulatoren
US7816435B2 (en) 2007-10-31 2010-10-19 Momentive Performance Materials Inc. Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom
TW200946105A (en) 2008-02-07 2009-11-16 Kyorin Seiyaku Kk Therapeutic agent or preventive agent for inflammatory bowel disease containing amino alcohol derivative as active ingredient
CN104800208A (zh) 2008-03-17 2015-07-29 埃科特莱茵药品有限公司 选择性s1p1受体激动剂的给药方案
CN103396346A (zh) * 2008-05-19 2013-11-20 杏林制药株式会社 光学活性氨基醇衍生物的制备方法
EP2305305A4 (de) 2008-05-20 2013-02-13 Kyorin Seiyaku Kk Mittel zur einleitung/erhaltung der remission
GB0901835D0 (en) 2009-02-04 2009-03-11 Syngenta Ltd Novel herbicides
GB0901834D0 (en) 2009-02-04 2009-03-11 Syngenta Ltd Novel herbicides
US8512690B2 (en) 2009-04-10 2013-08-20 Novartis Ag Derivatised proline containing peptide compounds as protease inhibitors
US20110182850A1 (en) 2009-04-10 2011-07-28 Trixi Brandl Organic compounds and their uses
DK2452944T3 (da) 2009-07-09 2014-10-27 Kyorin Seiyaku Kk Diphenylsulfidderivater samt lægemidler indeholdende dem som aktivt stof
KR101148098B1 (ko) 2010-04-30 2012-05-22 한국화학연구원 1-[4-(4-니트로-페녹시)-페닐]-프로판-1-온을 유효성분으로 함유하는 톡소포자충 및 콕시디움에 기인한 질환의 예방 및 치료용 조성물
PE20130612A1 (es) * 2010-05-06 2013-06-06 Novartis Ag Tratamiento de enfermedades autoinmunes
CN102917698A (zh) 2010-05-06 2013-02-06 诺瓦提斯公司 二芳基硫醚衍生物的给药方案
AU2011311880B2 (en) 2010-10-08 2014-07-24 Novartis Ag Vitamin E formulations of sulfamide NS3 inhibitors
TWI519539B (zh) 2010-12-21 2016-02-01 Kyorin Seiyaku Kk Diphenyl sulfide derivatives and pharmaceuticals as an active ingredient thereof
CN102863345A (zh) * 2011-07-06 2013-01-09 中国医学科学院药物研究所 胺基丙二醇类衍生物、其制备方法和其药物组合物与用途
HUE027461T2 (en) * 2011-07-13 2016-09-28 Basf Agro Bv Fungicide substituted 2- [2-haloalkyl-4- (phenoxyphenyl) -1- [1,2,4] triazol-1-yl-ethanol compounds
IN2014CN00832A (de) 2011-07-15 2015-04-03 Basf Se
CN103648281B (zh) 2011-07-15 2016-05-25 巴斯夫欧洲公司 杀真菌的烷基取代的2-[2-氯-4-(4-氯苯氧基)苯基]-1-[1,2,4]三唑-1-基乙醇化合物
UY34258A (es) 2011-08-15 2013-02-28 Basf Se Compuestos fungicidas de 1-{2-[2-halo-4-(4-halogen-fenoxi)-fenil]-2-alcoxi-2-alquinil/alquenil-etil}-1h-[1,2,4]triazol sustituidos
MX2014000824A (es) 2011-08-15 2014-02-27 Basf Se Compuestos fungicidas de 1-{2-[2-halo-4-(4-halogen-fenoxi)-fenil]- 2-alcoxi-3-metil-butil}-1h-[1,2,4]triazol sustituidos.
JP2014529594A (ja) 2011-08-15 2014-11-13 ビーエーエスエフ ソシエタス・ヨーロピアBasf Se 殺菌性置換1−{2−シクリルオキシ−2−[2−ハロ−4−(4−ハロゲン−フェノキシ)−フェニル]−エチル}−1h−[1,2,4]トリアゾール化合物
US9657043B2 (en) 2012-04-23 2017-05-23 Mitsubishi Tanabe Pharma Corporation Amine compound and use thereof for medical purposes
PL2934147T3 (pl) 2012-12-20 2020-06-29 BASF Agro B.V. Kompozycje zawierające związki triazolowe
PL3219707T3 (pl) 2013-01-09 2020-01-31 BASF Agro B.V. Sposób wytwarzania podstawionych oksiranów i triazoli
RU2669997C2 (ru) 2013-07-08 2018-10-17 Басф Агро Б.В. Композиции, содержащие триазольное соединение и биопестицид
CN104844486B (zh) * 2014-02-17 2018-10-30 中国医学科学院药物研究所 胺基丙二醇类衍生物、其制备方法和其药物组合物与用途
EA032078B1 (ru) 2014-06-25 2019-04-30 Басф Агро Б.В. Пестицидные композиции
BR112017009282A2 (pt) 2014-11-07 2018-01-30 Basf Se misturas fungicidas, composição pesticida, métodos para controlar pragas fitopatogênicas, para melhorar a fitossanidade e para proteção de material de propagação de plantas contra pragas, e, material de propagação de plantas.
BR112018068695B1 (pt) 2016-03-16 2022-12-27 Basf Se Uso de um composto e método para controlar fungos fitopatogênicos
US10905122B2 (en) 2016-03-16 2021-02-02 Basf Se Use of tetrazolinones for combating resistant phytopathogenic fungi on cereals
BR112018068705B1 (pt) 2016-03-16 2022-09-06 Basf Se Método para controlar fungos fitopatogênicos
BR112021001376A2 (pt) 2018-07-27 2021-04-20 Priothera Limited preparação farmacêutica, e usos de 2-amino-2-[4-(3-benziloxifeniltio)-2-clorofenil]etil-propano-1,3-diol, ou um sal farmaceuticamente aceitável do mesmo

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994008943A1 (en) 1992-10-21 1994-04-28 Yoshitomi Pharmaceutical Industries, Ltd. 2-amino-1,3-propanediol compound and immunosuppressant
EP0778263B1 (de) * 1994-08-22 2002-01-09 Welfide Corporation Benzolderivate und deren medizinische verwendung
PT1319651E (pt) 1997-04-04 2005-09-30 Mitsubishi Pharma Corp Composto 2-aminopropano-1,3-diol, sua utilizacao farmaceutica e seus intermediarios sinteticos

Also Published As

Publication number Publication date
EP1431275B1 (de) 2010-04-07
JP4152884B2 (ja) 2008-09-17
DE60235900D1 (de) 2010-05-20
JPWO2003029184A1 (ja) 2005-01-13
CA2460640C (en) 2011-03-29
US20040242654A1 (en) 2004-12-02
CA2460640A1 (en) 2003-04-10
EP1431275A4 (de) 2006-05-31
US6963012B2 (en) 2005-11-08
WO2003029184A1 (fr) 2003-04-10
EP1431275A1 (de) 2004-06-23

Similar Documents

Publication Publication Date Title
ATE463478T1 (de) Diaryletherderivat, dessen additionssalz und immunosuppressivum
CY1107272T1 (el) Παραγωγο διαρυλ σουλφιδιου, αλας προσθηκης εξ αυτου και ανοσοκατασταλτικο
EA200100411A1 (ru) Замещенные 3-цианохинолины в качестве ингибиторов протеинтирозинкиназ
ATE296826T1 (de) Pyrazolo(1,5)pyridinderivate
EA200100412A1 (ru) Замещенные 3-цианохинолины в качестве ингибиторов протеинтирозинкиназ
PT1453512E (pt) Derivados de acetileno tendo actividade antagonistica do mglur 5
ATE168992T1 (de) 7-substituierte-9-substituierte glycylamido-6- demethyl-6-deoxytetracycline
DE69718194T2 (de) Amidinophenyl-pyrrolidine, -pyrroline und -isoxazolidine und ihre derivate
DK0897904T3 (da) Fungicide 2-methoxybenzophenoner
DK0618190T3 (da) 9-(Substitueret glycyl)amido-6-(substitueret)-5-hydroxy-6-deoxy-tetracycliner
ATE180468T1 (de) Anthranilsäure derivate
HUP0102205A2 (hu) Növényvédőszer-készítmény
CY1106247T1 (el) Θειοφαινο- και θειαζολοσουλφοναμιδες ως αντινεοπλαστικοι παραγοντες
DK0842934T3 (da) 5-HT1F agonister
DE69716925T2 (de) Isoxazoline derivate und ihre verwendung als antimikroben
DE60116589D1 (de) Fungizide Phenylamidinderivative
BR9804027A (pt) Novos beta-ceto ésteres
MY136297A (en) Piperazine derivatives having sst1 antagonistic activity
DE69912193D1 (de) Substituierte 2-Hydroxybenzophenone, ihre Herstellung, ihre Verwendung als fungizide und ihre fungizide Zusammensetzungen
ATE286499T1 (de) Fungizide phenylimidate-derivate
ES2087499T3 (es) Derivados de bis(fenil)etano.
DK1328275T3 (da) Substituerede 4,5-dihydro-1,2,4-triazin-3-oner, 1,2,4-triazin-3-oner og deres anvendelse som fungicider og insekticider
ATE321760T1 (de) N-aryl-2-oxazolidinone und deren derivate
DE69915688D1 (de) Benzonaphtyridin-1,8 derivate
DK1433480T3 (da) Lægemiddel indeholdende pyrimidin-derivat

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties