ATE463478T1 - Diaryletherderivat, dessen additionssalz und immunosuppressivum - Google Patents
Diaryletherderivat, dessen additionssalz und immunosuppressivumInfo
- Publication number
- ATE463478T1 ATE463478T1 AT02768056T AT02768056T ATE463478T1 AT E463478 T1 ATE463478 T1 AT E463478T1 AT 02768056 T AT02768056 T AT 02768056T AT 02768056 T AT02768056 T AT 02768056T AT E463478 T1 ATE463478 T1 AT E463478T1
- Authority
- AT
- Austria
- Prior art keywords
- immunosuppressant
- addition salt
- diaryl ether
- ether derivative
- diaryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/64—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001297400 | 2001-09-27 | ||
JP2002216191 | 2002-07-25 | ||
PCT/JP2002/009864 WO2003029184A1 (fr) | 2001-09-27 | 2002-09-25 | Derive d'ether de diaryle, son sel d'addition et son immunosuppresseur |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE463478T1 true ATE463478T1 (de) | 2010-04-15 |
Family
ID=26623110
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02768056T ATE463478T1 (de) | 2001-09-27 | 2002-09-25 | Diaryletherderivat, dessen additionssalz und immunosuppressivum |
Country Status (7)
Country | Link |
---|---|
US (1) | US6963012B2 (de) |
EP (1) | EP1431275B1 (de) |
JP (1) | JP4152884B2 (de) |
AT (1) | ATE463478T1 (de) |
CA (1) | CA2460640C (de) |
DE (1) | DE60235900D1 (de) |
WO (1) | WO2003029184A1 (de) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2461212C (en) * | 2001-09-27 | 2010-08-17 | Kyorin Pharmaceutical Co., Ltd. | Diaryl sulfide derivatives, salts thereof and immunosuppressive agents using the same |
DK1471054T3 (da) * | 2002-01-11 | 2009-11-09 | Daiichi Sankyo Co Ltd | Aminoalkohol-derivat eller phosphonsyre-derivat og medicinsk sammensætning, der indeholder disse |
EP1944026B1 (de) | 2002-05-16 | 2013-06-26 | Novartis AG | Verwendung von EDG-Rezeptorbindemitteln bei Krebs |
EP2617711A1 (de) | 2002-09-19 | 2013-07-24 | Kyorin Pharmaceutical Co., Ltd. | Aminoalkoholderivate, Salze davon und Immunsuppressiva |
PL375053A1 (en) | 2002-09-24 | 2005-11-14 | Novartis Ag | Sphingosine-1-phosphate receptor agonists in the treatment of demyelinating disorders |
PE20131352A1 (es) | 2003-04-08 | 2013-11-14 | Novartis Ag | Composicion farmaceutica que contiene un agonista del receptor s1p y un alcohol de azucar |
EP1622860B1 (de) * | 2003-04-30 | 2012-02-29 | Novartis AG | Aminopropanol-derivate als modulatoren des sphingosin-1-phosphat-rezeptors |
GB0320638D0 (en) | 2003-09-03 | 2003-10-01 | Novartis Ag | Organic compounds |
GB0324210D0 (en) * | 2003-10-15 | 2003-11-19 | Novartis Ag | Organic compounds |
GB0329498D0 (en) | 2003-12-19 | 2004-01-28 | Novartis Ag | Organic compounds |
TW200526548A (en) * | 2003-12-25 | 2005-08-16 | Sankyo Co | Ether derivatives |
GB0500020D0 (en) | 2005-01-04 | 2005-02-09 | Novartis Ag | Organic compounds |
TWI355934B (en) * | 2004-02-24 | 2012-01-11 | Sankyo Co | Pharmaceutical composition for treatment or prophy |
EP2363149A1 (de) | 2004-05-03 | 2011-09-07 | Novartis AG | Kombinationen mit einem S1P-Rezeptoragonist und einem JAK3-Kinaseinhibitor |
DK1772145T3 (da) * | 2004-07-16 | 2011-05-30 | Kyorin Seiyaku Kk | Fremgangsmåde til effektiv anvendelse af medicin og fremgangsmåde til forebyggelse af bivirkninger |
TW200611687A (en) * | 2004-07-29 | 2006-04-16 | Sankyo Co | Pharmaceutical compositions used for immunosuppressant |
CA2574664C (en) | 2004-07-30 | 2013-01-15 | Novartis Ag | Compound formulations of 2-amino-1,3-propanediol compounds |
ES2563034T3 (es) | 2004-10-12 | 2016-03-10 | Kyorin Pharmaceutical Co., Ltd. | Procedimiento para producir hidrocloruro de 2-amino-2-[2-[4-(3-benciloxifeniltio)-2-clorofenil]etil]-1,3-propanodiol e hidratos del mismo, e intermedios para la producción de los mismos |
KR20140095109A (ko) | 2004-11-29 | 2014-07-31 | 노파르티스 아게 | S1p 수용체 효능제의 투여 용법 |
GB0504544D0 (en) | 2005-03-04 | 2005-04-13 | Novartis Ag | Organic compounds |
TWI418350B (zh) * | 2005-06-24 | 2013-12-11 | Sankyo Co | 含有ppar調節劑之醫藥組成物的用途 |
AR057455A1 (es) * | 2005-07-22 | 2007-12-05 | Merck & Co Inc | Inhibidores de la transcriptasa reversa de vih y composicion farmaceutica |
PL1926483T3 (pl) * | 2005-09-09 | 2011-05-31 | Novartis Ag | Leczenie chorób autoimmunologicznych |
BRPI0617077A2 (pt) * | 2005-10-07 | 2015-01-06 | Kyorin Seiyaku Kk | Agente terapêutico para tratamento de doenças do fígado contendo 2-amina-1, 3-propanediol derivativo como ingrediente ativo, e método para tratamento de doenças do fígado |
TWI389683B (zh) * | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
MX2008013119A (es) | 2006-04-11 | 2008-10-21 | Novartis Ag | Inhibidores de hcv/vih y sus usos. |
ES2491224T3 (es) | 2006-04-28 | 2014-09-05 | Mitsubishi Tanabe Pharma Corporation | Compuesto de 2-aminobutanol y su uso para fines médicos |
TW200815600A (en) | 2006-08-04 | 2008-04-01 | Daiichi Sankyo Co Ltd | An enzyme for phosphorizing a medicine |
RS53080B (en) | 2006-08-08 | 2014-06-30 | Kyorin Pharmaceutical Co. Ltd. | AMINOPHOSPHORIC ACID ETHAR DERIVATIVE AND S1P RECEPTOR MODULATOR CONTAINING THE SAME AS THE ACTIVE INGREDIENT |
KR20090041424A (ko) * | 2006-08-08 | 2009-04-28 | 교린 세이야꾸 가부시키 가이샤 | 아미노알코올 유도체 및 그것들을 유효성분으로 하는 면역 억제제 |
EP2168944B1 (de) * | 2007-06-14 | 2016-05-11 | Mitsubishi Tanabe Pharma Corporation | Aminverbindung und ihre pharmazeutische verwendung |
EP3733162A1 (de) | 2007-10-12 | 2020-11-04 | Novartis AG | Zusammensetzung mit sphingosin-1-phosphat (s1p)-rezeptormodulatoren |
US7816435B2 (en) | 2007-10-31 | 2010-10-19 | Momentive Performance Materials Inc. | Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom |
TW200946105A (en) | 2008-02-07 | 2009-11-16 | Kyorin Seiyaku Kk | Therapeutic agent or preventive agent for inflammatory bowel disease containing amino alcohol derivative as active ingredient |
CN104800208A (zh) | 2008-03-17 | 2015-07-29 | 埃科特莱茵药品有限公司 | 选择性s1p1受体激动剂的给药方案 |
CN103396346A (zh) * | 2008-05-19 | 2013-11-20 | 杏林制药株式会社 | 光学活性氨基醇衍生物的制备方法 |
EP2305305A4 (de) | 2008-05-20 | 2013-02-13 | Kyorin Seiyaku Kk | Mittel zur einleitung/erhaltung der remission |
GB0901835D0 (en) | 2009-02-04 | 2009-03-11 | Syngenta Ltd | Novel herbicides |
GB0901834D0 (en) | 2009-02-04 | 2009-03-11 | Syngenta Ltd | Novel herbicides |
US8512690B2 (en) | 2009-04-10 | 2013-08-20 | Novartis Ag | Derivatised proline containing peptide compounds as protease inhibitors |
US20110182850A1 (en) | 2009-04-10 | 2011-07-28 | Trixi Brandl | Organic compounds and their uses |
DK2452944T3 (da) | 2009-07-09 | 2014-10-27 | Kyorin Seiyaku Kk | Diphenylsulfidderivater samt lægemidler indeholdende dem som aktivt stof |
KR101148098B1 (ko) | 2010-04-30 | 2012-05-22 | 한국화학연구원 | 1-[4-(4-니트로-페녹시)-페닐]-프로판-1-온을 유효성분으로 함유하는 톡소포자충 및 콕시디움에 기인한 질환의 예방 및 치료용 조성물 |
PE20130612A1 (es) * | 2010-05-06 | 2013-06-06 | Novartis Ag | Tratamiento de enfermedades autoinmunes |
CN102917698A (zh) | 2010-05-06 | 2013-02-06 | 诺瓦提斯公司 | 二芳基硫醚衍生物的给药方案 |
AU2011311880B2 (en) | 2010-10-08 | 2014-07-24 | Novartis Ag | Vitamin E formulations of sulfamide NS3 inhibitors |
TWI519539B (zh) | 2010-12-21 | 2016-02-01 | Kyorin Seiyaku Kk | Diphenyl sulfide derivatives and pharmaceuticals as an active ingredient thereof |
CN102863345A (zh) * | 2011-07-06 | 2013-01-09 | 中国医学科学院药物研究所 | 胺基丙二醇类衍生物、其制备方法和其药物组合物与用途 |
HUE027461T2 (en) * | 2011-07-13 | 2016-09-28 | Basf Agro Bv | Fungicide substituted 2- [2-haloalkyl-4- (phenoxyphenyl) -1- [1,2,4] triazol-1-yl-ethanol compounds |
IN2014CN00832A (de) | 2011-07-15 | 2015-04-03 | Basf Se | |
CN103648281B (zh) | 2011-07-15 | 2016-05-25 | 巴斯夫欧洲公司 | 杀真菌的烷基取代的2-[2-氯-4-(4-氯苯氧基)苯基]-1-[1,2,4]三唑-1-基乙醇化合物 |
UY34258A (es) | 2011-08-15 | 2013-02-28 | Basf Se | Compuestos fungicidas de 1-{2-[2-halo-4-(4-halogen-fenoxi)-fenil]-2-alcoxi-2-alquinil/alquenil-etil}-1h-[1,2,4]triazol sustituidos |
MX2014000824A (es) | 2011-08-15 | 2014-02-27 | Basf Se | Compuestos fungicidas de 1-{2-[2-halo-4-(4-halogen-fenoxi)-fenil]- 2-alcoxi-3-metil-butil}-1h-[1,2,4]triazol sustituidos. |
JP2014529594A (ja) | 2011-08-15 | 2014-11-13 | ビーエーエスエフ ソシエタス・ヨーロピアBasf Se | 殺菌性置換1−{2−シクリルオキシ−2−[2−ハロ−4−(4−ハロゲン−フェノキシ)−フェニル]−エチル}−1h−[1,2,4]トリアゾール化合物 |
US9657043B2 (en) | 2012-04-23 | 2017-05-23 | Mitsubishi Tanabe Pharma Corporation | Amine compound and use thereof for medical purposes |
PL2934147T3 (pl) | 2012-12-20 | 2020-06-29 | BASF Agro B.V. | Kompozycje zawierające związki triazolowe |
PL3219707T3 (pl) | 2013-01-09 | 2020-01-31 | BASF Agro B.V. | Sposób wytwarzania podstawionych oksiranów i triazoli |
RU2669997C2 (ru) | 2013-07-08 | 2018-10-17 | Басф Агро Б.В. | Композиции, содержащие триазольное соединение и биопестицид |
CN104844486B (zh) * | 2014-02-17 | 2018-10-30 | 中国医学科学院药物研究所 | 胺基丙二醇类衍生物、其制备方法和其药物组合物与用途 |
EA032078B1 (ru) | 2014-06-25 | 2019-04-30 | Басф Агро Б.В. | Пестицидные композиции |
BR112017009282A2 (pt) | 2014-11-07 | 2018-01-30 | Basf Se | misturas fungicidas, composição pesticida, métodos para controlar pragas fitopatogênicas, para melhorar a fitossanidade e para proteção de material de propagação de plantas contra pragas, e, material de propagação de plantas. |
BR112018068695B1 (pt) | 2016-03-16 | 2022-12-27 | Basf Se | Uso de um composto e método para controlar fungos fitopatogênicos |
US10905122B2 (en) | 2016-03-16 | 2021-02-02 | Basf Se | Use of tetrazolinones for combating resistant phytopathogenic fungi on cereals |
BR112018068705B1 (pt) | 2016-03-16 | 2022-09-06 | Basf Se | Método para controlar fungos fitopatogênicos |
BR112021001376A2 (pt) | 2018-07-27 | 2021-04-20 | Priothera Limited | preparação farmacêutica, e usos de 2-amino-2-[4-(3-benziloxifeniltio)-2-clorofenil]etil-propano-1,3-diol, ou um sal farmaceuticamente aceitável do mesmo |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994008943A1 (en) | 1992-10-21 | 1994-04-28 | Yoshitomi Pharmaceutical Industries, Ltd. | 2-amino-1,3-propanediol compound and immunosuppressant |
EP0778263B1 (de) * | 1994-08-22 | 2002-01-09 | Welfide Corporation | Benzolderivate und deren medizinische verwendung |
PT1319651E (pt) | 1997-04-04 | 2005-09-30 | Mitsubishi Pharma Corp | Composto 2-aminopropano-1,3-diol, sua utilizacao farmaceutica e seus intermediarios sinteticos |
-
2002
- 2002-09-25 WO PCT/JP2002/009864 patent/WO2003029184A1/ja active Application Filing
- 2002-09-25 DE DE60235900T patent/DE60235900D1/de not_active Expired - Lifetime
- 2002-09-25 US US10/490,345 patent/US6963012B2/en not_active Expired - Fee Related
- 2002-09-25 JP JP2003532439A patent/JP4152884B2/ja not_active Expired - Fee Related
- 2002-09-25 EP EP02768056A patent/EP1431275B1/de not_active Expired - Lifetime
- 2002-09-25 AT AT02768056T patent/ATE463478T1/de not_active IP Right Cessation
- 2002-09-25 CA CA2460640A patent/CA2460640C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1431275B1 (de) | 2010-04-07 |
JP4152884B2 (ja) | 2008-09-17 |
DE60235900D1 (de) | 2010-05-20 |
JPWO2003029184A1 (ja) | 2005-01-13 |
CA2460640C (en) | 2011-03-29 |
US20040242654A1 (en) | 2004-12-02 |
CA2460640A1 (en) | 2003-04-10 |
EP1431275A4 (de) | 2006-05-31 |
US6963012B2 (en) | 2005-11-08 |
WO2003029184A1 (fr) | 2003-04-10 |
EP1431275A1 (de) | 2004-06-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE463478T1 (de) | Diaryletherderivat, dessen additionssalz und immunosuppressivum | |
CY1107272T1 (el) | Παραγωγο διαρυλ σουλφιδιου, αλας προσθηκης εξ αυτου και ανοσοκατασταλτικο | |
EA200100411A1 (ru) | Замещенные 3-цианохинолины в качестве ингибиторов протеинтирозинкиназ | |
ATE296826T1 (de) | Pyrazolo(1,5)pyridinderivate | |
EA200100412A1 (ru) | Замещенные 3-цианохинолины в качестве ингибиторов протеинтирозинкиназ | |
PT1453512E (pt) | Derivados de acetileno tendo actividade antagonistica do mglur 5 | |
ATE168992T1 (de) | 7-substituierte-9-substituierte glycylamido-6- demethyl-6-deoxytetracycline | |
DE69718194T2 (de) | Amidinophenyl-pyrrolidine, -pyrroline und -isoxazolidine und ihre derivate | |
DK0897904T3 (da) | Fungicide 2-methoxybenzophenoner | |
DK0618190T3 (da) | 9-(Substitueret glycyl)amido-6-(substitueret)-5-hydroxy-6-deoxy-tetracycliner | |
ATE180468T1 (de) | Anthranilsäure derivate | |
HUP0102205A2 (hu) | Növényvédőszer-készítmény | |
CY1106247T1 (el) | Θειοφαινο- και θειαζολοσουλφοναμιδες ως αντινεοπλαστικοι παραγοντες | |
DK0842934T3 (da) | 5-HT1F agonister | |
DE69716925T2 (de) | Isoxazoline derivate und ihre verwendung als antimikroben | |
DE60116589D1 (de) | Fungizide Phenylamidinderivative | |
BR9804027A (pt) | Novos beta-ceto ésteres | |
MY136297A (en) | Piperazine derivatives having sst1 antagonistic activity | |
DE69912193D1 (de) | Substituierte 2-Hydroxybenzophenone, ihre Herstellung, ihre Verwendung als fungizide und ihre fungizide Zusammensetzungen | |
ATE286499T1 (de) | Fungizide phenylimidate-derivate | |
ES2087499T3 (es) | Derivados de bis(fenil)etano. | |
DK1328275T3 (da) | Substituerede 4,5-dihydro-1,2,4-triazin-3-oner, 1,2,4-triazin-3-oner og deres anvendelse som fungicider og insekticider | |
ATE321760T1 (de) | N-aryl-2-oxazolidinone und deren derivate | |
DE69915688D1 (de) | Benzonaphtyridin-1,8 derivate | |
DK1433480T3 (da) | Lægemiddel indeholdende pyrimidin-derivat |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |