ATE451913T1 - Subkutane implantate, die über einen längeren zeitraum einen wirkstoff freisetzen - Google Patents

Subkutane implantate, die über einen längeren zeitraum einen wirkstoff freisetzen

Info

Publication number
ATE451913T1
ATE451913T1 AT07788137T AT07788137T ATE451913T1 AT E451913 T1 ATE451913 T1 AT E451913T1 AT 07788137 T AT07788137 T AT 07788137T AT 07788137 T AT07788137 T AT 07788137T AT E451913 T1 ATE451913 T1 AT E451913T1
Authority
AT
Austria
Prior art keywords
release
subcutaneous implants
active substance
longer period
substance over
Prior art date
Application number
AT07788137T
Other languages
English (en)
Inventor
Patrice Mauriac
Pierre Marion
Original Assignee
Mediolanum Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mediolanum Pharmaceuticals Ltd filed Critical Mediolanum Pharmaceuticals Ltd
Application granted granted Critical
Publication of ATE451913T1 publication Critical patent/ATE451913T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
AT07788137T 2006-08-02 2007-08-01 Subkutane implantate, die über einen längeren zeitraum einen wirkstoff freisetzen ATE451913T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001545A ITMI20061545A1 (it) 2006-08-02 2006-08-02 Particelle in grado di rilasciare il principio attivo per un periodo prolungato di tempo
PCT/EP2007/057969 WO2008015238A2 (en) 2006-08-02 2007-08-01 Subcutaneous implants releasing an active principle over an extended period of time

Publications (1)

Publication Number Publication Date
ATE451913T1 true ATE451913T1 (de) 2010-01-15

Family

ID=37846057

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07788137T ATE451913T1 (de) 2006-08-02 2007-08-01 Subkutane implantate, die über einen längeren zeitraum einen wirkstoff freisetzen

Country Status (18)

Country Link
US (1) US20100003298A1 (de)
EP (1) EP2054037B1 (de)
JP (1) JP2009545564A (de)
KR (1) KR20090037946A (de)
CN (1) CN101553212A (de)
AT (1) ATE451913T1 (de)
AU (1) AU2007280397A1 (de)
BR (1) BRPI0714515A2 (de)
CA (1) CA2659441A1 (de)
DE (1) DE602007003854D1 (de)
EA (1) EA017292B1 (de)
ES (1) ES2337419T3 (de)
HK (1) HK1129835A1 (de)
IT (1) ITMI20061545A1 (de)
MX (1) MX2009001232A (de)
PL (1) PL2054037T3 (de)
PT (1) PT2054037E (de)
WO (1) WO2008015238A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101977624A (zh) * 2008-03-20 2011-02-16 欧加农股份有限公司 用于增加骨矿物质密度的药物组合物的制备

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1311686C (en) * 1986-06-25 1992-12-22 John Weldon Shell Controlled release bioerodible drug delivery system
US5490962A (en) * 1993-10-18 1996-02-13 Massachusetts Institute Of Technology Preparation of medical devices by solid free-form fabrication methods
US5942253A (en) * 1995-10-12 1999-08-24 Immunex Corporation Prolonged release of GM-CSF
US5817343A (en) * 1996-05-14 1998-10-06 Alkermes, Inc. Method for fabricating polymer-based controlled-release devices
IT1304152B1 (it) * 1998-12-10 2001-03-08 Mediolanum Farmaceutici Srl Composizioni comprendenti un peptide ed acido polilattico-glicolicoatte alla preparazione di impianti sottocutanei aventi un prolungato
PT1638535E (pt) * 2003-06-26 2007-11-08 Mediolanum Pharmaceuticals Ltd Implantes subcutâneos com libertação inicial de princípio activo limitada e subsequente sua libertação extensiva com variação linear
AU2005219413A1 (en) * 2004-03-02 2005-09-15 Massachusetts Institute Of Technology Nanocell drug delivery system

Also Published As

Publication number Publication date
AU2007280397A1 (en) 2008-02-07
BRPI0714515A2 (pt) 2013-04-24
EA017292B1 (ru) 2012-11-30
US20100003298A1 (en) 2010-01-07
PT2054037E (pt) 2010-03-24
DE602007003854D1 (de) 2010-01-28
EA200900247A1 (ru) 2009-06-30
CA2659441A1 (en) 2008-02-07
EP2054037B1 (de) 2009-12-16
ES2337419T3 (es) 2010-04-23
EP2054037A2 (de) 2009-05-06
KR20090037946A (ko) 2009-04-16
WO2008015238A8 (en) 2008-06-05
MX2009001232A (es) 2009-04-28
HK1129835A1 (en) 2009-12-11
PL2054037T3 (pl) 2010-05-31
JP2009545564A (ja) 2009-12-24
CN101553212A (zh) 2009-10-07
WO2008015238A3 (en) 2008-03-20
ITMI20061545A1 (it) 2008-02-03
WO2008015238A2 (en) 2008-02-07

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