ATE449125T1 - Mittels wasserabweisender gruppen funktionalisierte verzweigte polyaminosäuren und deren verwendung, insbesondere für therapeutische zwecke - Google Patents

Mittels wasserabweisender gruppen funktionalisierte verzweigte polyaminosäuren und deren verwendung, insbesondere für therapeutische zwecke

Info

Publication number
ATE449125T1
ATE449125T1 AT05791929T AT05791929T ATE449125T1 AT E449125 T1 ATE449125 T1 AT E449125T1 AT 05791929 T AT05791929 T AT 05791929T AT 05791929 T AT05791929 T AT 05791929T AT E449125 T1 ATE449125 T1 AT E449125T1
Authority
AT
Austria
Prior art keywords
polyaminoacids
branched
active principles
particles
transporting
Prior art date
Application number
AT05791929T
Other languages
English (en)
Inventor
Remi Soula
Gauthier Pouliquen
You-Ping Chan
Original Assignee
Flamel Tech Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flamel Tech Sa filed Critical Flamel Tech Sa
Application granted granted Critical
Publication of ATE449125T1 publication Critical patent/ATE449125T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/88—Polyamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/48—Polymers modified by chemical after-treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Polyamides (AREA)
  • Cosmetics (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
AT05791929T 2004-07-30 2005-07-19 Mittels wasserabweisender gruppen funktionalisierte verzweigte polyaminosäuren und deren verwendung, insbesondere für therapeutische zwecke ATE449125T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0408477A FR2873703B1 (fr) 2004-07-30 2004-07-30 Polyaminoacides branches, fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques
PCT/FR2005/050594 WO2006021706A1 (fr) 2004-07-30 2005-07-19 Polyaminoacides branches, fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques

Publications (1)

Publication Number Publication Date
ATE449125T1 true ATE449125T1 (de) 2009-12-15

Family

ID=34949824

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05791929T ATE449125T1 (de) 2004-07-30 2005-07-19 Mittels wasserabweisender gruppen funktionalisierte verzweigte polyaminosäuren und deren verwendung, insbesondere für therapeutische zwecke

Country Status (9)

Country Link
US (1) US8206744B2 (de)
EP (1) EP1771498B1 (de)
JP (1) JP4871867B2 (de)
AT (1) ATE449125T1 (de)
CA (1) CA2573791A1 (de)
DE (1) DE602005017787D1 (de)
ES (1) ES2336688T3 (de)
FR (1) FR2873703B1 (de)
WO (1) WO2006021706A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2873704B1 (fr) * 2004-07-30 2006-12-08 Flamel Technologies Sa Polyaminoacides fonctionnalises par des greffons hydrophobes portant une charge anionique et leurs applications notamment therapeutiques
CA2656077C (en) * 2006-06-15 2014-12-09 Marc Mckennon A process for the preparation of poly-alpha-glutamic acid and derivatives thereof
JP5258189B2 (ja) * 2006-11-09 2013-08-07 学校法人 関西大学 柔軟性生分解性ポリマー
FR2915748B1 (fr) * 2007-05-03 2012-10-19 Flamel Tech Sa Acides polyglutamiques fonctionnalises par des groupes cationiques et des groupements hydrophobes et leurs applications, notamment therapeutiques
TWI448485B (zh) * 2010-08-03 2014-08-11 Univ Nat Taiwan Normal 半互穿網絡型水膠聚合物、其製造方法及包含其之水泥組成物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4351337A (en) 1973-05-17 1982-09-28 Arthur D. Little, Inc. Biodegradable, implantable drug delivery device, and process for preparing and using the same
JPS60100516A (ja) 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
DE3581471D1 (de) 1984-10-19 1991-02-28 Battelle Memorial Institute Durch mikroorganismen abbaubares polypeptid und seine verwendung fuer die fortschreitende abgabe von medikamenten.
CH667874A5 (fr) 1985-12-19 1988-11-15 Battelle Memorial Institute Polypeptide synthetique biodegradable et son utilisation pour la preparation de medicaments.
KR940003548U (ko) 1992-08-14 1994-02-21 김형술 세탁물 건조기
US6153193A (en) 1993-04-28 2000-11-28 Supratek Pharma Inc. Compositions for targeting biological agents
FR2732218B1 (fr) 1995-03-28 1997-08-01 Flamel Tech Sa Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s) et leurs procedes de preparation
US6331289B1 (en) * 1996-10-28 2001-12-18 Nycomed Imaging As Targeted diagnostic/therapeutic agents having more than one different vectors
GB9811059D0 (en) 1998-05-23 1998-07-22 Univ Strathclyde Polyamino acid vesicles
FR2786098B1 (fr) 1998-11-20 2003-05-30 Flamel Tech Sa Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s), suspension colloidale les comprenant et leurs procedes de fabrication
FR2801226B1 (fr) 1999-11-23 2002-01-25 Flamel Tech Sa Suspension colloidale de particules submicroniques de vectorisation de principes actifs et son mode de preparation
FR2840614B1 (fr) * 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
FR2843117B1 (fr) * 2002-07-30 2004-10-15 Flamel Tech Sa Polyaminoacides fonctionnalises par au moins un groupement hydrophobe et leurs applications notamment therapeutiques
CA2508751A1 (fr) 2002-12-04 2004-07-22 Flamel Technologies Polyaminoacides fonctionnalises par au moins un groupement (oligo)aminoacide et leurs applications notamment therapeutiques
JP2006050312A (ja) * 2004-08-05 2006-02-16 Canon Inc プリンタサーバ装置及びデータ処理方法

Also Published As

Publication number Publication date
US20090305948A1 (en) 2009-12-10
FR2873703A1 (fr) 2006-02-03
WO2006021706A1 (fr) 2006-03-02
EP1771498B1 (de) 2009-11-18
JP4871867B2 (ja) 2012-02-08
DE602005017787D1 (de) 2009-12-31
US8206744B2 (en) 2012-06-26
ES2336688T3 (es) 2010-04-15
EP1771498A1 (de) 2007-04-11
FR2873703B1 (fr) 2006-12-08
CA2573791A1 (fr) 2006-03-02
JP2008508388A (ja) 2008-03-21

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