US6048734A
(en)
|
1995-09-15 |
2000-04-11 |
The Regents Of The University Of Michigan |
Thermal microvalves in a fluid flow method
|
US8900811B2
(en)
|
2000-11-16 |
2014-12-02 |
Caliper Life Sciences, Inc. |
Method and apparatus for generating thermal melting curves in a microfluidic device
|
US6692700B2
(en)
|
2001-02-14 |
2004-02-17 |
Handylab, Inc. |
Heat-reduction methods and systems related to microfluidic devices
|
US7010391B2
(en)
|
2001-03-28 |
2006-03-07 |
Handylab, Inc. |
Methods and systems for control of microfluidic devices
|
US7323140B2
(en)
*
|
2001-03-28 |
2008-01-29 |
Handylab, Inc. |
Moving microdroplets in a microfluidic device
|
US7829025B2
(en)
|
2001-03-28 |
2010-11-09 |
Venture Lending & Leasing Iv, Inc. |
Systems and methods for thermal actuation of microfluidic devices
|
US6852287B2
(en)
|
2001-09-12 |
2005-02-08 |
Handylab, Inc. |
Microfluidic devices having a reduced number of input and output connections
|
US8895311B1
(en)
|
2001-03-28 |
2014-11-25 |
Handylab, Inc. |
Methods and systems for control of general purpose microfluidic devices
|
US7440684B2
(en)
|
2001-04-12 |
2008-10-21 |
Spaid Michael A |
Method and apparatus for improved temperature control in microfluidic devices
|
AU2003256675A1
(en)
*
|
2002-07-26 |
2004-02-16 |
Applera Corporation |
Mg-mediated hot start biochemical reactions
|
KR100959101B1
(ko)
*
|
2003-02-20 |
2010-05-25 |
삼성전자주식회사 |
Pcr 반응기 및 pcr 반응기의 입구와 출구의 개폐를조절하는 방법
|
US7041481B2
(en)
*
|
2003-03-14 |
2006-05-09 |
The Regents Of The University Of California |
Chemical amplification based on fluid partitioning
|
CA2784762A1
(en)
|
2003-04-10 |
2004-10-28 |
President And Fellows Of Harvard College |
Formation and control of fluidic species
|
DE10318139B4
(de)
*
|
2003-04-18 |
2005-02-17 |
PRO DESIGN Gesellschaft für Produktentwicklung mbH |
Selbstkonfigurerbarer Biochip
|
US7038472B1
(en)
|
2003-05-12 |
2006-05-02 |
Caliper Life Sciences, Inc. |
Methods and systems for measuring internal dimensions of microscale structures
|
US7731906B2
(en)
|
2003-07-31 |
2010-06-08 |
Handylab, Inc. |
Processing particle-containing samples
|
EP2662135A3
(de)
|
2003-08-27 |
2013-12-25 |
President and Fellows of Harvard College |
Verfahren zur Mischung von Tröpfchen in einem Mikrokanal
|
WO2005022147A1
(en)
|
2003-08-28 |
2005-03-10 |
Celula, Inc. |
Methods and apparatus for sorting cells using an optical switch in a microfluidic channel network
|
US9597644B2
(en)
*
|
2003-09-05 |
2017-03-21 |
Stokes Bio Limited |
Methods for culturing and analyzing cells
|
WO2005023427A1
(en)
|
2003-09-05 |
2005-03-17 |
Stokes Bio Limited |
A microfluidic analysis system
|
DE10353985A1
(de)
*
|
2003-11-19 |
2005-06-23 |
Olympus Biosystems Gmbh |
Einrichtung und Verfahren zum Manipulieren und Analysieren von Mikroobjekten auf Grundlage eines zumindest bereichsweise als fluidisches Mikrosystem oder/und Chipsystem ausgeführten Mikrosystems
|
JP4592060B2
(ja)
*
|
2004-04-26 |
2010-12-01 |
キヤノン株式会社 |
Pcr増幅反応装置、ならびに、該装置を利用するpcr増幅反応方法
|
US8852862B2
(en)
|
2004-05-03 |
2014-10-07 |
Handylab, Inc. |
Method for processing polynucleotide-containing samples
|
AU2005241080B2
(en)
|
2004-05-03 |
2011-08-11 |
Handylab, Inc. |
Processing polynucleotide-containing samples
|
US7622296B2
(en)
*
|
2004-05-28 |
2009-11-24 |
Wafergen, Inc. |
Apparatus and method for multiplex analysis
|
CA2575545A1
(en)
|
2004-07-28 |
2006-10-12 |
Toru Takahashi |
Methods for monitoring genomic dna of organisms
|
US9132398B2
(en)
|
2007-10-12 |
2015-09-15 |
Rheonix, Inc. |
Integrated microfluidic device and methods
|
AU2006214085A1
(en)
*
|
2005-02-18 |
2006-08-24 |
Canon U.S. Life Sciences, Inc. |
Devices and methods for identifying genomic DNA of organisms
|
ATE474663T1
(de)
*
|
2005-06-15 |
2010-08-15 |
Rhodia Operations |
Mikrofluidikzirkulationsvorrichtung zur bestimmung von parametern einer physikalischen und/oder chemischen transformation und verwendung davon
|
EP1754536B1
(de)
*
|
2005-08-16 |
2008-12-24 |
Agilent Technologies, Inc. |
Flüssigkeitseinspritzsystem
|
EP1941035B1
(de)
|
2005-09-01 |
2017-11-22 |
Canon U.S. Life Sciences, Inc. |
Verfahren und molekulardiagnostische vorrichtung zum nachweis, zur analyse und zur identifizierung genomischer dns
|
WO2007047606A2
(en)
*
|
2005-10-17 |
2007-04-26 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Electrokinetic thermal cycler and reactor
|
ATE523244T1
(de)
|
2006-02-07 |
2011-09-15 |
Stokes Bio Ltd |
Flüssigkeitsbrückesystem und verfahren
|
AU2007225038B2
(en)
|
2006-03-15 |
2013-08-29 |
Perkinelmer Health Sciences, Inc. |
Integrated nucleic acid assays
|
ES2692380T3
(es)
|
2006-03-24 |
2018-12-03 |
Handylab, Inc. |
Método para realizar PCR con un cartucho con varias pistas
|
US11806718B2
(en)
|
2006-03-24 |
2023-11-07 |
Handylab, Inc. |
Fluorescence detector for microfluidic diagnostic system
|
US8088616B2
(en)
|
2006-03-24 |
2012-01-03 |
Handylab, Inc. |
Heater unit for microfluidic diagnostic system
|
US7998708B2
(en)
|
2006-03-24 |
2011-08-16 |
Handylab, Inc. |
Microfluidic system for amplifying and detecting polynucleotides in parallel
|
US10900066B2
(en)
|
2006-03-24 |
2021-01-26 |
Handylab, Inc. |
Microfluidic system for amplifying and detecting polynucleotides in parallel
|
US7846314B2
(en)
*
|
2006-05-11 |
2010-12-07 |
Agilent Technologies , Inc |
Handling a plurality of samples
|
US7629124B2
(en)
*
|
2006-06-30 |
2009-12-08 |
Canon U.S. Life Sciences, Inc. |
Real-time PCR in micro-channels
|
WO2008060604A2
(en)
|
2006-11-14 |
2008-05-22 |
Handylab, Inc. |
Microfluidic system for amplifying and detecting polynucleotides in parallel
|
US8765076B2
(en)
|
2006-11-14 |
2014-07-01 |
Handylab, Inc. |
Microfluidic valve and method of making same
|
CN101711257A
(zh)
|
2007-01-22 |
2010-05-19 |
瓦弗根公司 |
用于高通量化学反应的装置
|
US8691164B2
(en)
*
|
2007-04-20 |
2014-04-08 |
Celula, Inc. |
Cell sorting system and methods
|
US20080280466A1
(en)
*
|
2007-05-08 |
2008-11-13 |
Imation Corp. |
USB memory device
|
KR101346468B1
(ko)
*
|
2007-05-18 |
2014-01-02 |
메디메이트 홀딩 비.브이. |
액체 중의 분석물질의 농도를 측정하기 위한 플러그를 갖는 시험 칩, 시험 칩용 하우징 및 플러그용 소켓
|
US8182763B2
(en)
|
2007-07-13 |
2012-05-22 |
Handylab, Inc. |
Rack for sample tubes and reagent holders
|
US8133671B2
(en)
|
2007-07-13 |
2012-03-13 |
Handylab, Inc. |
Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
|
US8287820B2
(en)
|
2007-07-13 |
2012-10-16 |
Handylab, Inc. |
Automated pipetting apparatus having a combined liquid pump and pipette head system
|
USD621060S1
(en)
|
2008-07-14 |
2010-08-03 |
Handylab, Inc. |
Microfluidic cartridge
|
US9618139B2
(en)
|
2007-07-13 |
2017-04-11 |
Handylab, Inc. |
Integrated heater and magnetic separator
|
US9186677B2
(en)
|
2007-07-13 |
2015-11-17 |
Handylab, Inc. |
Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
|
US8105783B2
(en)
|
2007-07-13 |
2012-01-31 |
Handylab, Inc. |
Microfluidic cartridge
|
US20090136385A1
(en)
|
2007-07-13 |
2009-05-28 |
Handylab, Inc. |
Reagent Tube
|
EP3741869A1
(de)
|
2007-07-13 |
2020-11-25 |
Handylab, Inc. |
Materialien zur erfassung von polynukleotiden und verfahren zur verwendung davon
|
US8016260B2
(en)
|
2007-07-19 |
2011-09-13 |
Formulatrix, Inc. |
Metering assembly and method of dispensing fluid
|
US20090042737A1
(en)
*
|
2007-08-09 |
2009-02-12 |
Katz Andrew S |
Methods and Devices for Correlated, Multi-Parameter Single Cell Measurements and Recovery of Remnant Biological Material
|
US9114397B2
(en)
*
|
2007-10-25 |
2015-08-25 |
Canon U.S. Life Sciences, Inc. |
Method of reducing cross-contamination in continuous amplification reactions in a channel
|
US9393566B2
(en)
*
|
2008-06-23 |
2016-07-19 |
Canon U.S. Life Sciences, Inc. |
System and method for temperature referencing for melt curve data collection
|
USD618820S1
(en)
|
2008-07-11 |
2010-06-29 |
Handylab, Inc. |
Reagent holder
|
USD787087S1
(en)
|
2008-07-14 |
2017-05-16 |
Handylab, Inc. |
Housing
|
US8322918B2
(en)
*
|
2008-08-01 |
2012-12-04 |
Eppendorf Ag |
Tempering apparatus with testing device and method for testing a tempering apparatus
|
EP2153901A1
(de)
*
|
2008-08-01 |
2010-02-17 |
Eppendorf Ag |
Temperierungsvorrichtung mit Testmöglichkeit und Verfahren zum Testen einer Temperierungsvorrichtung
|
US9156010B2
(en)
|
2008-09-23 |
2015-10-13 |
Bio-Rad Laboratories, Inc. |
Droplet-based assay system
|
US9417190B2
(en)
|
2008-09-23 |
2016-08-16 |
Bio-Rad Laboratories, Inc. |
Calibrations and controls for droplet-based assays
|
US8663920B2
(en)
|
2011-07-29 |
2014-03-04 |
Bio-Rad Laboratories, Inc. |
Library characterization by digital assay
|
US8633015B2
(en)
|
2008-09-23 |
2014-01-21 |
Bio-Rad Laboratories, Inc. |
Flow-based thermocycling system with thermoelectric cooler
|
US9764322B2
(en)
|
2008-09-23 |
2017-09-19 |
Bio-Rad Laboratories, Inc. |
System for generating droplets with pressure monitoring
|
US11130128B2
(en)
|
2008-09-23 |
2021-09-28 |
Bio-Rad Laboratories, Inc. |
Detection method for a target nucleic acid
|
US10512910B2
(en)
|
2008-09-23 |
2019-12-24 |
Bio-Rad Laboratories, Inc. |
Droplet-based analysis method
|
US9399215B2
(en)
|
2012-04-13 |
2016-07-26 |
Bio-Rad Laboratories, Inc. |
Sample holder with a well having a wicking promoter
|
US9492797B2
(en)
|
2008-09-23 |
2016-11-15 |
Bio-Rad Laboratories, Inc. |
System for detection of spaced droplets
|
US8951939B2
(en)
|
2011-07-12 |
2015-02-10 |
Bio-Rad Laboratories, Inc. |
Digital assays with multiplexed detection of two or more targets in the same optical channel
|
US9132394B2
(en)
|
2008-09-23 |
2015-09-15 |
Bio-Rad Laboratories, Inc. |
System for detection of spaced droplets
|
US8709762B2
(en)
|
2010-03-02 |
2014-04-29 |
Bio-Rad Laboratories, Inc. |
System for hot-start amplification via a multiple emulsion
|
US8100293B2
(en)
|
2009-01-23 |
2012-01-24 |
Formulatrix, Inc. |
Microfluidic dispensing assembly
|
WO2010141131A1
(en)
|
2009-06-04 |
2010-12-09 |
Lockheed Martin Corporation |
Multiple-sample microfluidic chip for dna analysis
|
JP6155418B2
(ja)
|
2009-09-02 |
2017-07-05 |
バイオ−ラッド・ラボラトリーズ・インコーポレーテッド |
多重エマルジョンの合体による、流体を混合するためのシステム
|
US9132423B2
(en)
|
2010-01-29 |
2015-09-15 |
Micronics, Inc. |
Sample-to-answer microfluidic cartridge
|
US8399198B2
(en)
|
2010-03-02 |
2013-03-19 |
Bio-Rad Laboratories, Inc. |
Assays with droplets transformed into capsules
|
CA2767113A1
(en)
|
2010-03-25 |
2011-09-29 |
Bio-Rad Laboratories, Inc. |
Detection system for droplet-based assays
|
JP2013524171A
(ja)
|
2010-03-25 |
2013-06-17 |
クァンタライフ・インコーポレーテッド |
液滴ベースのアッセイのための液滴の発生
|
CA2767114A1
(en)
|
2010-03-25 |
2011-09-29 |
Bio-Rad Laboratories, Inc. |
Droplet transport system for detection
|
CA2814720C
(en)
|
2010-10-15 |
2016-12-13 |
Lockheed Martin Corporation |
Micro fluidic optic design
|
DE202011110979U1
(de)
|
2010-11-01 |
2017-12-04 |
Bio-Rad Laboratories, Inc. |
System zum Bilden von Emulsionen
|
WO2012129187A1
(en)
|
2011-03-18 |
2012-09-27 |
Bio-Rad Laboratories, Inc. |
Multiplexed digital assays with combinatorial use of signals
|
CA3082652A1
(en)
|
2011-04-15 |
2012-10-18 |
Becton, Dickinson And Company |
Scanning real-time microfluidic thermocycler and methods for synchronized thermocycling and scanning optical detection
|
AU2012249759A1
(en)
|
2011-04-25 |
2013-11-07 |
Bio-Rad Laboratories, Inc. |
Methods and compositions for nucleic acid analysis
|
USD692162S1
(en)
|
2011-09-30 |
2013-10-22 |
Becton, Dickinson And Company |
Single piece reagent holder
|
CN106996984B
(zh)
|
2011-09-30 |
2018-11-27 |
贝克顿·迪金森公司 |
组合试剂条
|
WO2013067202A1
(en)
|
2011-11-04 |
2013-05-10 |
Handylab, Inc. |
Polynucleotide sample preparation device
|
EP2810080B1
(de)
|
2012-02-03 |
2024-03-27 |
Becton, Dickinson and Company |
Externe dateien zur verteilung von molekularen diagnostischen tests und bestimmung der kompatibilität zwischen tests
|
US9322054B2
(en)
|
2012-02-22 |
2016-04-26 |
Lockheed Martin Corporation |
Microfluidic cartridge
|
JP2013208066A
(ja)
|
2012-03-30 |
2013-10-10 |
Seiko Epson Corp |
熱サイクル装置及び熱サイクル装置の制御方法
|
JP5971463B2
(ja)
|
2012-03-30 |
2016-08-17 |
セイコーエプソン株式会社 |
熱サイクル装置及び熱サイクル装置の制御方法
|
JP5935985B2
(ja)
*
|
2012-03-30 |
2016-06-15 |
セイコーエプソン株式会社 |
熱サイクル装置
|
JP6216494B2
(ja)
*
|
2012-03-30 |
2017-10-18 |
セイコーエプソン株式会社 |
熱サイクル装置及び熱サイクル装置の制御方法
|
US10584381B2
(en)
|
2012-08-14 |
2020-03-10 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US10221442B2
(en)
|
2012-08-14 |
2019-03-05 |
10X Genomics, Inc. |
Compositions and methods for sample processing
|
US10273541B2
(en)
|
2012-08-14 |
2019-04-30 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
CN114891871A
(zh)
|
2012-08-14 |
2022-08-12 |
10X基因组学有限公司 |
微胶囊组合物及方法
|
US9951386B2
(en)
|
2014-06-26 |
2018-04-24 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US9701998B2
(en)
|
2012-12-14 |
2017-07-11 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US10323279B2
(en)
|
2012-08-14 |
2019-06-18 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US11591637B2
(en)
|
2012-08-14 |
2023-02-28 |
10X Genomics, Inc. |
Compositions and methods for sample processing
|
US9388465B2
(en)
|
2013-02-08 |
2016-07-12 |
10X Genomics, Inc. |
Polynucleotide barcode generation
|
US10752949B2
(en)
|
2012-08-14 |
2020-08-25 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US10533221B2
(en)
|
2012-12-14 |
2020-01-14 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
EP3567116A1
(de)
|
2012-12-14 |
2019-11-13 |
10X Genomics, Inc. |
Verfahren und systeme zur verarbeitung von polynukleotiden
|
EP2935559B1
(de)
|
2012-12-21 |
2020-09-16 |
PerkinElmer Health Sciences, Inc. |
Fluoreszenznachweissystem
|
CN104919191B
(zh)
|
2012-12-21 |
2019-07-09 |
精密公司 |
流体回路及相关的制造方法
|
WO2014100743A2
(en)
|
2012-12-21 |
2014-06-26 |
Micronics, Inc. |
Low elasticity films for microfluidic use
|
US9995412B2
(en)
|
2013-03-01 |
2018-06-12 |
Wave 80 Biosciences, Inc. |
Long-throw microfluidic actuator
|
JP2016516562A
(ja)
*
|
2013-03-01 |
2016-06-09 |
ウェーブ 80 バイオサイエンシズ インコーポレイテッド |
マイクロ流体処理のための方法およびシステム
|
JP6472788B2
(ja)
|
2013-05-07 |
2019-02-20 |
マイクロニクス, インコーポレイテッド |
粘土鉱物およびアルカリ性溶液を使用して核酸含有試料を調製するための方法
|
CN105189784B
(zh)
|
2013-05-07 |
2020-06-30 |
珀金埃尔默健康科学有限公司 |
用于制备和分析核酸的装置
|
WO2014182844A1
(en)
|
2013-05-07 |
2014-11-13 |
Micronics, Inc. |
Microfluidic devices and methods for performing serum separation and blood cross-matching
|
JP2015154722A
(ja)
|
2014-02-20 |
2015-08-27 |
セイコーエプソン株式会社 |
核酸増幅反応容器及び核酸増幅反応装置
|
US9694361B2
(en)
|
2014-04-10 |
2017-07-04 |
10X Genomics, Inc. |
Fluidic devices, systems, and methods for encapsulating and partitioning reagents, and applications of same
|
CN113249435A
(zh)
|
2014-06-26 |
2021-08-13 |
10X基因组学有限公司 |
分析来自单个细胞或细胞群体的核酸的方法
|
BR112017008877A2
(pt)
|
2014-10-29 |
2018-07-03 |
10X Genomics Inc |
métodos e composições para sequenciamento de ácido nucleico-alvo
|
US9975122B2
(en)
|
2014-11-05 |
2018-05-22 |
10X Genomics, Inc. |
Instrument systems for integrated sample processing
|
AU2016207023B2
(en)
|
2015-01-12 |
2019-12-05 |
10X Genomics, Inc. |
Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same
|
CN107407685B
(zh)
|
2015-02-20 |
2021-08-03 |
宝生物工程(美国)有限公司 |
快速精确分配、可视化和分析单个细胞的方法
|
CN115651972A
(zh)
|
2015-02-24 |
2023-01-31 |
10X 基因组学有限公司 |
用于靶向核酸序列覆盖的方法
|
WO2016137973A1
(en)
|
2015-02-24 |
2016-09-01 |
10X Genomics Inc |
Partition processing methods and systems
|
EP3384048B1
(de)
|
2015-12-04 |
2021-03-24 |
10X Genomics, Inc. |
Verfahren und zusammensetzungen zur nukleinsäureanalyse
|
JP6206688B2
(ja)
*
|
2016-05-11 |
2017-10-04 |
セイコーエプソン株式会社 |
熱サイクル装置
|
WO2017197338A1
(en)
|
2016-05-13 |
2017-11-16 |
10X Genomics, Inc. |
Microfluidic systems and methods of use
|
KR102429636B1
(ko)
|
2016-06-27 |
2022-08-05 |
조에티스 서비시즈 엘엘씨 |
수정된 도관을 갖는 장치
|
US11460405B2
(en)
|
2016-07-21 |
2022-10-04 |
Takara Bio Usa, Inc. |
Multi-Z imaging and dispensing with multi-well devices
|
US10815525B2
(en)
|
2016-12-22 |
2020-10-27 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US10011872B1
(en)
|
2016-12-22 |
2018-07-03 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US10550429B2
(en)
|
2016-12-22 |
2020-02-04 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
CN117512066A
(zh)
|
2017-01-30 |
2024-02-06 |
10X基因组学有限公司 |
用于基于微滴的单细胞条形编码的方法和系统
|
JP7203041B2
(ja)
*
|
2017-04-21 |
2023-01-12 |
ゾエティス・サービシーズ・エルエルシー |
微小流体の分析のためのシステム、デバイス、及び方法
|
CN109526228B
(zh)
|
2017-05-26 |
2022-11-25 |
10X基因组学有限公司 |
转座酶可接近性染色质的单细胞分析
|
US10400235B2
(en)
|
2017-05-26 |
2019-09-03 |
10X Genomics, Inc. |
Single cell analysis of transposase accessible chromatin
|
SG11201913654QA
(en)
|
2017-11-15 |
2020-01-30 |
10X Genomics Inc |
Functionalized gel beads
|
US10829815B2
(en)
|
2017-11-17 |
2020-11-10 |
10X Genomics, Inc. |
Methods and systems for associating physical and genetic properties of biological particles
|
EP3775271A1
(de)
|
2018-04-06 |
2021-02-17 |
10X Genomics, Inc. |
Systeme und verfahren zur qualitätskontrolle in einer einzelzellenverarbeitung
|