ATE445716T1 - Standardisiertes und optimiertes quantitatives reverse-transkriptase echtzeit- polymerasekettenreaktionsverfahren zum nachweis von minimalen resterkrankungen bei leukämie - Google Patents

Standardisiertes und optimiertes quantitatives reverse-transkriptase echtzeit- polymerasekettenreaktionsverfahren zum nachweis von minimalen resterkrankungen bei leukämie

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Publication number
ATE445716T1
ATE445716T1 AT07007462T AT07007462T ATE445716T1 AT E445716 T1 ATE445716 T1 AT E445716T1 AT 07007462 T AT07007462 T AT 07007462T AT 07007462 T AT07007462 T AT 07007462T AT E445716 T1 ATE445716 T1 AT E445716T1
Authority
AT
Austria
Prior art keywords
leukemia
standardized
residual disease
minimal residual
chain reaction
Prior art date
Application number
AT07007462T
Other languages
English (en)
Inventor
Jean Gabert
Emmanuel Beillard
Wanli Bi
Dongen Jacques Van
Original Assignee
Univ Aix Marseille Ii
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Filing date
Publication date
Application filed by Univ Aix Marseille Ii filed Critical Univ Aix Marseille Ii
Application granted granted Critical
Publication of ATE445716T1 publication Critical patent/ATE445716T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT07007462T 2003-03-07 2004-03-08 Standardisiertes und optimiertes quantitatives reverse-transkriptase echtzeit- polymerasekettenreaktionsverfahren zum nachweis von minimalen resterkrankungen bei leukämie ATE445716T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03290572A EP1454994A1 (de) 2003-03-07 2003-03-07 Standardisiertes und optimiertes quantitatives Reverse-Transkriptase-Echtzeit-Polymerasekettenreaktionsverfahren zum Nachweis von minimalen Resterkrankungen bei Leukämie

Publications (1)

Publication Number Publication Date
ATE445716T1 true ATE445716T1 (de) 2009-10-15

Family

ID=32799106

Family Applications (2)

Application Number Title Priority Date Filing Date
AT07007462T ATE445716T1 (de) 2003-03-07 2004-03-08 Standardisiertes und optimiertes quantitatives reverse-transkriptase echtzeit- polymerasekettenreaktionsverfahren zum nachweis von minimalen resterkrankungen bei leukämie
AT04718310T ATE518004T1 (de) 2003-03-07 2004-03-08 Standardisiertes und optimiertes quantitatives reverse-transkriptase echtzeit- polymerasekettenreaktion verfahren zum nachweis von minimalen resterkrankungen bei leukämie

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT04718310T ATE518004T1 (de) 2003-03-07 2004-03-08 Standardisiertes und optimiertes quantitatives reverse-transkriptase echtzeit- polymerasekettenreaktion verfahren zum nachweis von minimalen resterkrankungen bei leukämie

Country Status (7)

Country Link
US (2) US20060240434A1 (de)
EP (5) EP1454994A1 (de)
JP (1) JP4706863B2 (de)
AT (2) ATE445716T1 (de)
DE (1) DE602004023659D1 (de)
ES (2) ES2370339T3 (de)
WO (1) WO2004078020A2 (de)

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US8206920B2 (en) * 2007-03-26 2012-06-26 Arnold Ganser Diagnostic assay for the specific treatment of acute myeloid leukemia
CN101624621B (zh) * 2008-07-11 2012-01-18 北京大学人民医院 一种定量检测BCR/ABL mRNA水平的试剂盒
US9777332B2 (en) 2011-03-31 2017-10-03 St. Jude Children's Research Hospital Methods and compositions for identifying minimal residual disease in acute lymphoblastic leukemia
JP2015508644A (ja) * 2012-02-08 2015-03-23 インサイト ジェネティクス インコーポレイテッド 癌の診断および治療のためのｒｏｓ１の融合体に関する方法および組成物
MA35216B1 (fr) * 2012-09-13 2014-07-03 Mascir Sondes et amorces pour la detection du gene bcr-abl en reaction duplex
CN102925556B (zh) * 2012-09-29 2014-09-17 童永清 一种检测m BCR融合基因mRNA表达量的试剂盒
CN102876799B (zh) * 2012-10-18 2014-01-01 北京大学人民医院 用于检测mll相关融合基因的多重实时定量pcr试剂盒
MA36330B1 (fr) * 2013-10-10 2016-04-29 Mascir Morrocan Foundation For Advanced Science Innovation & Res Kit de diagnostic de la leucemie myeloide chronique en reaction multiplex et ses applications dans le suivi du traitement et de la maladie residuelle
US20170307619A1 (en) * 2014-10-02 2017-10-26 Université de Montréal MARKERS OF POOR PROGNOSIS ACUTE MYELOID LEUKEMIAS (AMLs) AND USES THEREOF
JP6531312B2 (ja) * 2014-10-17 2019-06-19 東洋鋼鈑株式会社 Ｂｃｒ−ａｂｌ阻害剤耐性関連変異の検出方法及びこれを用いたｂｃｒ−ａｂｌ阻害剤耐性を予測するためのデータ取得方法
WO2016183679A1 (en) * 2015-05-21 2016-11-24 Université de Montréal Prognostic markers of acute myeloid leukemia survival
CN106399462A (zh) * 2015-07-27 2017-02-15 上海睿玻生物科技有限公司 一种bcr-abl融合基因扩增试剂盒和检测试剂盒
RU2638800C2 (ru) * 2015-12-29 2017-12-15 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) Способ определения маркеров наличия опухолевых в-лимфобластов
CN107674914A (zh) * 2016-08-02 2018-02-09 熊术道 一步单管法定量rt‑pcr检测慢性髓系白血病bcr‑abl1基因的表达量
CN108823306A (zh) * 2017-05-03 2018-11-16 杭州赫玛生物科技有限公司 检测白血病细胞的系统和方法
CN108676848B (zh) * 2018-05-31 2022-04-22 上海科医联创医学检验所有限公司 用于检测融合基因的混合基因、标准质粒、试剂盒及其制备方法
CN109554472A (zh) * 2018-12-18 2019-04-02 武汉迪安医学检验实验室有限公司 一种用于检测tel-aml1融合基因的试剂盒
CN111235148A (zh) * 2020-03-26 2020-06-05 迈杰转化医学研究(苏州)有限公司 一种dna探针池、包含其的淋巴瘤检测试剂盒及其制备方法和应用
CN111733238B (zh) * 2020-05-26 2021-08-03 广州血康陆道培生物技术有限公司 一种鉴别PML-RARα融合基因3种剪切体的引物组及其试剂盒和应用
CN112280866A (zh) * 2020-11-24 2021-01-29 福州艾迪康医学检验所有限公司 荧光定量pcr技术筛查急性早幼粒细胞白血病相关14种融合基因的方法、引物及探针
CN113637756A (zh) * 2021-08-18 2021-11-12 武汉良培医学检验实验室有限公司 一种用于多靶点单孔同时检测的探针组及其试剂盒
CN116970704B (zh) * 2023-08-22 2024-05-17 迈杰转化医学研究(苏州)有限公司 一种检测bcr-abl激酶区突变的引物探针组合及其应用

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* Cited by examiner, † Cited by third party
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WO1997004080A1 (fr) * 1995-07-14 1997-02-06 Fuji Yakuhin Kogyo Kabushiki Kaisha Nouvelle proteine et anticorps monoclonal specifique a cette derniere
WO2001064207A2 (en) * 2000-03-01 2001-09-07 University Of South Florida Methods of modulating cell-adhesion mediated drug resistance
DE60126592T2 (de) * 2000-04-03 2007-11-22 Corixa Corp., Hamilton Verfahren, zusammensetzungen und kits zur identifizierung und überwachung von brustkrebs
WO2002002739A2 (en) * 2000-06-29 2002-01-10 University Of Florida Ubiquitin ligase
US7363168B2 (en) * 2001-10-02 2008-04-22 Stratagene California Adaptive baseline algorithm for quantitative PCR
US7198897B2 (en) * 2001-12-19 2007-04-03 Brandeis University Late-PCR
DE10209071A1 (de) * 2002-02-28 2003-09-25 Roboscreen Ges Fuer Molekulare Standardisierte Polynukleotidsysteme, Verfahren zu ihrer Herstellung und ihre Verwendung
US20030170724A1 (en) * 2002-03-08 2003-09-11 Anderson David C. Methods of identifying target polypeptides

Also Published As

Publication number Publication date
EP1806416B9 (de) 2010-03-10
EP2204457A2 (de) 2010-07-07
WO2004078020A2 (en) 2004-09-16
US20110223595A1 (en) 2011-09-15
EP1454994A1 (de) 2004-09-08
EP1806416A2 (de) 2007-07-11
EP1601796B1 (de) 2011-07-27
EP1806415A2 (de) 2007-07-11
US20060240434A1 (en) 2006-10-26
EP2204457A3 (de) 2011-01-19
JP4706863B2 (ja) 2011-06-22
ES2370339T3 (es) 2011-12-14
EP1806416B1 (de) 2009-10-14
JP2006519601A (ja) 2006-08-31
EP1806416A3 (de) 2007-07-18
WO2004078020A3 (en) 2005-03-31
ES2337301T3 (es) 2010-04-22
EP1601796A2 (de) 2005-12-07
ATE518004T1 (de) 2011-08-15
DE602004023659D1 (de) 2009-11-26
EP1806415A3 (de) 2007-07-18

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