ATE442168T1 - Anisotrope nanoporíse beschichtungen für medizinische implantate - Google Patents
Anisotrope nanoporíse beschichtungen für medizinische implantateInfo
- Publication number
- ATE442168T1 ATE442168T1 AT07845258T AT07845258T ATE442168T1 AT E442168 T1 ATE442168 T1 AT E442168T1 AT 07845258 T AT07845258 T AT 07845258T AT 07845258 T AT07845258 T AT 07845258T AT E442168 T1 ATE442168 T1 AT E442168T1
- Authority
- AT
- Austria
- Prior art keywords
- coatings
- anisotropic
- relates
- medical implants
- nano
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
- A61C8/0013—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy with a surface layer, coating
- A61C8/0015—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy with a surface layer, coating being a conversion layer, e.g. oxide layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/146—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0018—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the shape
- A61C8/0037—Details of the shape
- A61C2008/0046—Textured surface, e.g. roughness, microstructure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0003—Not used, see subgroups
- A61C8/0004—Consolidating natural teeth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
- A61C8/0013—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy with a surface layer, coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
- A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
- Y10T428/24942—Structurally defined web or sheet [e.g., overall dimension, etc.] including components having same physical characteristic in differing degree
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/249921—Web or sheet containing structurally defined element or component
- Y10T428/249953—Composite having voids in a component [e.g., porous, cellular, etc.]
- Y10T428/249978—Voids specified as micro
- Y10T428/249979—Specified thickness of void-containing component [absolute or relative] or numerical cell dimension
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06114127 | 2006-05-17 | ||
EP06118544A EP1891988A1 (de) | 2006-08-07 | 2006-08-07 | Anisotropische, nanoporöse Beschichtungen für medizinisch anwendbare Implantate |
PCT/IB2007/051869 WO2007148240A2 (en) | 2006-05-17 | 2007-05-16 | Anisotropic nanoporous coatings for medical implants |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE442168T1 true ATE442168T1 (de) | 2009-09-15 |
Family
ID=38833836
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07845258T ATE442168T1 (de) | 2006-05-17 | 2007-05-16 | Anisotrope nanoporíse beschichtungen für medizinische implantate |
Country Status (8)
Country | Link |
---|---|
US (2) | US20090177273A1 (de) |
EP (1) | EP2026853B1 (de) |
JP (1) | JP5290962B2 (de) |
CN (1) | CN101448534B (de) |
AT (1) | ATE442168T1 (de) |
CA (1) | CA2651982C (de) |
DE (1) | DE602007002407D1 (de) |
WO (1) | WO2007148240A2 (de) |
Families Citing this family (83)
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US7713297B2 (en) | 1998-04-11 | 2010-05-11 | Boston Scientific Scimed, Inc. | Drug-releasing stent with ceramic-containing layer |
AU2002345328A1 (en) | 2001-06-27 | 2003-03-03 | Remon Medical Technologies Ltd. | Method and device for electrochemical formation of therapeutic species in vivo |
US8840660B2 (en) | 2006-01-05 | 2014-09-23 | Boston Scientific Scimed, Inc. | Bioerodible endoprostheses and methods of making the same |
US8089029B2 (en) | 2006-02-01 | 2012-01-03 | Boston Scientific Scimed, Inc. | Bioabsorbable metal medical device and method of manufacture |
US20070224235A1 (en) | 2006-03-24 | 2007-09-27 | Barron Tenney | Medical devices having nanoporous coatings for controlled therapeutic agent delivery |
US8187620B2 (en) | 2006-03-27 | 2012-05-29 | Boston Scientific Scimed, Inc. | Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents |
US8048150B2 (en) | 2006-04-12 | 2011-11-01 | Boston Scientific Scimed, Inc. | Endoprosthesis having a fiber meshwork disposed thereon |
US8815275B2 (en) | 2006-06-28 | 2014-08-26 | Boston Scientific Scimed, Inc. | Coatings for medical devices comprising a therapeutic agent and a metallic material |
JP2009542359A (ja) | 2006-06-29 | 2009-12-03 | ボストン サイエンティフィック リミテッド | 選択的被覆部を備えた医療装置 |
JP2009545407A (ja) | 2006-08-02 | 2009-12-24 | ボストン サイエンティフィック サイムド,インコーポレイテッド | 三次元分解制御を備えたエンドプロテーゼ |
JP2010503469A (ja) | 2006-09-14 | 2010-02-04 | ボストン サイエンティフィック リミテッド | 薬物溶出性皮膜を有する医療デバイス |
US8052744B2 (en) | 2006-09-15 | 2011-11-08 | Boston Scientific Scimed, Inc. | Medical devices and methods of making the same |
EP2068782B1 (de) | 2006-09-15 | 2011-07-27 | Boston Scientific Limited | Biologisch erodierbare endoprothesen |
DE602007011114D1 (de) | 2006-09-15 | 2011-01-20 | Boston Scient Scimed Inc | Biologisch erodierbare endoprothese mit biostabilen anorganischen schichten |
EP2081616B1 (de) | 2006-09-15 | 2017-11-01 | Boston Scientific Scimed, Inc. | Bioerodierbare endoprothesen und herstellungsverfahren dafür |
US8002821B2 (en) | 2006-09-18 | 2011-08-23 | Boston Scientific Scimed, Inc. | Bioerodible metallic ENDOPROSTHESES |
US7981150B2 (en) | 2006-11-09 | 2011-07-19 | Boston Scientific Scimed, Inc. | Endoprosthesis with coatings |
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JP2010535541A (ja) | 2007-08-03 | 2010-11-25 | ボストン サイエンティフィック リミテッド | 広い表面積を有する医療器具用のコーティング |
US8052745B2 (en) | 2007-09-13 | 2011-11-08 | Boston Scientific Scimed, Inc. | Endoprosthesis |
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JP5634516B2 (ja) * | 2009-07-14 | 2014-12-03 | デバイオテック・ソシエテ・アノニム | 機械的に安定なコーティング |
DE102009056052B4 (de) * | 2009-11-26 | 2014-07-10 | Humboldt-Universität Zu Berlin | Anordnung mit einem Träger und einer Schicht |
ES2681875T3 (es) * | 2010-01-22 | 2018-09-17 | Concept Medical Research Private Limited | Dispositivos médicos insertables con una capa porosa para administrar nanovehículos a un sitio objetivo y métodos de preparación del mismo |
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US9522263B2 (en) | 2010-04-28 | 2016-12-20 | Kimberly-Clark Worldwide, Inc. | Device for delivery of rheumatoid arthritis medication |
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CN103463674B (zh) * | 2010-11-17 | 2015-05-20 | 重庆润泽医药有限公司 | 一种医用植入材料多孔钽的制备方法 |
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JP2015513301A (ja) * | 2012-01-30 | 2015-05-07 | ヒポクラット | 負に帯電した血管ステント |
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CN103656758B (zh) * | 2012-09-26 | 2014-12-10 | 中国科学院化学研究所 | 一种仿天然血管中膜层结构与功能的组织工程支架及其制备方法 |
EP2737894A1 (de) | 2012-12-03 | 2014-06-04 | Debiotech S.A. | Intelligente Beschichtung für implantierbare Vorrichtungen |
JP2015091354A (ja) * | 2014-12-24 | 2015-05-14 | デバイオテック・ソシエテ・アノニム | 異方性コーティングにおける多孔性の制御 |
WO2016126789A1 (en) * | 2015-02-03 | 2016-08-11 | University Of Maine System Board Of Trustees | Soft tissue in-growth of porous, three-dimensionally printed, transcutaneous implants of varying material and pore geometry |
CA3005238A1 (en) * | 2015-11-20 | 2017-05-26 | Forsight Vision4, Inc. | Porous structures for extended release drug delivery devices |
CN105796217B (zh) * | 2016-05-17 | 2018-10-26 | 常州市第二人民医院 | 一种血管支架 |
CN106038010B (zh) * | 2016-05-19 | 2018-01-09 | 刘歆 | 一种心血管动脉支架 |
KR102102612B1 (ko) * | 2017-03-30 | 2020-04-21 | 한양대학교 산학협력단 | 경화 온도에 따라 표면 구조 조절이 가능한 다공성 필름의 제조방법 |
EP3632881A4 (de) * | 2017-05-22 | 2021-03-03 | Hangzhou Erran Technology Co. Ltd. | Biologisch aktive nanooxidkeramikschicht |
WO2019087126A1 (en) * | 2017-11-06 | 2019-05-09 | 3M Innovative Properties Company | Dental crown having a highly retentive coating and methods for making the same |
JP7203344B2 (ja) | 2017-12-27 | 2023-01-13 | パナソニックIpマネジメント株式会社 | 誘導加熱調理器 |
EP3714910A1 (de) * | 2019-03-29 | 2020-09-30 | Picosun Oy | Implantatbeschichtung |
CN110759313B (zh) * | 2019-10-31 | 2023-07-25 | 潍坊歌尔微电子有限公司 | Mems传感器组件制造方法以及以该法制造的传感器组件 |
CN112973650B (zh) * | 2021-02-08 | 2022-02-08 | 厦门大学 | 一种纳微复合球及其制备方法和应用 |
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US4605406A (en) * | 1984-08-03 | 1986-08-12 | Medtronic, Inc. | Method for fabricating prosthesis material |
US5947896A (en) * | 1996-04-26 | 1999-09-07 | United States Surgical Corporation | Heart stabilizer apparatus and method for use |
DE59609458D1 (de) * | 1996-12-23 | 2002-08-22 | Robert Mathys Stiftung Bettlac | Bioaktive oberflächenschicht für knochenimplantate |
US20010029351A1 (en) * | 1998-04-16 | 2001-10-11 | Robert Falotico | Drug combinations and delivery devices for the prevention and treatment of vascular disease |
DE19855421C2 (de) * | 1998-11-02 | 2001-09-20 | Alcove Surfaces Gmbh | Implantat |
US6764507B2 (en) * | 2000-10-16 | 2004-07-20 | Conor Medsystems, Inc. | Expandable medical device with improved spatial distribution |
EP1319416B1 (de) * | 2001-12-12 | 2004-11-03 | Hehrlein, Christoph, Dr. | Poröser Metallstent mit keramischer Beschichtung |
US20060134160A1 (en) * | 2002-09-13 | 2006-06-22 | The University Of British Columbia | Calcium phosphate coated implantable medical devices and processes for making same |
JP2006514848A (ja) * | 2002-11-13 | 2006-05-18 | セタゴン インコーポレーティッド | 多孔質層を有する医療装置およびその作製方法 |
US20050037052A1 (en) * | 2003-08-13 | 2005-02-17 | Medtronic Vascular, Inc. | Stent coating with gradient porosity |
EP1786363B1 (de) * | 2004-08-13 | 2010-04-14 | Setagon, Inc. | Herstellungsverfahren für medizinprodukte mit nanoporösen schichten |
US20060199876A1 (en) * | 2005-03-04 | 2006-09-07 | The University Of British Columbia | Bioceramic composite coatings and process for making same |
-
2007
- 2007-05-16 AT AT07845258T patent/ATE442168T1/de not_active IP Right Cessation
- 2007-05-16 CN CN2007800179537A patent/CN101448534B/zh not_active Expired - Fee Related
- 2007-05-16 DE DE200760002407 patent/DE602007002407D1/de active Active
- 2007-05-16 WO PCT/IB2007/051869 patent/WO2007148240A2/en active Application Filing
- 2007-05-16 US US12/300,182 patent/US20090177273A1/en not_active Abandoned
- 2007-05-16 JP JP2009510605A patent/JP5290962B2/ja not_active Expired - Fee Related
- 2007-05-16 CA CA 2651982 patent/CA2651982C/en not_active Expired - Fee Related
- 2007-05-16 EP EP20070845258 patent/EP2026853B1/de not_active Not-in-force
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2015
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WO2007148240A3 (en) | 2008-06-12 |
EP2026853A2 (de) | 2009-02-25 |
CN101448534B (zh) | 2012-10-03 |
US20150217096A1 (en) | 2015-08-06 |
CN101448534A (zh) | 2009-06-03 |
JP2009537208A (ja) | 2009-10-29 |
EP2026853B1 (de) | 2009-09-09 |
JP5290962B2 (ja) | 2013-09-18 |
US20090177273A1 (en) | 2009-07-09 |
WO2007148240A2 (en) | 2007-12-27 |
CA2651982C (en) | 2014-07-15 |
CA2651982A1 (en) | 2007-12-27 |
DE602007002407D1 (de) | 2009-10-22 |
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