ATE428684T1 - Verwendung von bisaminen zur verstärkung der antimikrobiellen wirkung von wässrigen zusammensetzungen - Google Patents

Verwendung von bisaminen zur verstärkung der antimikrobiellen wirkung von wässrigen zusammensetzungen

Info

Publication number
ATE428684T1
ATE428684T1 AT04813634T AT04813634T ATE428684T1 AT E428684 T1 ATE428684 T1 AT E428684T1 AT 04813634 T AT04813634 T AT 04813634T AT 04813634 T AT04813634 T AT 04813634T AT E428684 T1 ATE428684 T1 AT E428684T1
Authority
AT
Austria
Prior art keywords
bisamines
increase
aqueous compositions
antimicrobial effect
amines
Prior art date
Application number
AT04813634T
Other languages
English (en)
Inventor
Nissanke Dassanayake
Thomas Carey
Ronald Schlitzer
David Meadows
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Application granted granted Critical
Publication of ATE428684T1 publication Critical patent/ATE428684T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/14Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic the nitrogen atom of the amino group being further bound to hydrocarbon groups substituted by amino groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/18Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with hydroxy groups and at least two amino groups bound to the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
AT04813634T 2003-12-09 2004-12-09 Verwendung von bisaminen zur verstärkung der antimikrobiellen wirkung von wässrigen zusammensetzungen ATE428684T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52828703P 2003-12-09 2003-12-09
PCT/US2004/041332 WO2005056515A2 (en) 2003-12-09 2004-12-09 Use of bis-amines to enhance the antimicrobial activity of aqueous compositions

Publications (1)

Publication Number Publication Date
ATE428684T1 true ATE428684T1 (de) 2009-05-15

Family

ID=34676836

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04813634T ATE428684T1 (de) 2003-12-09 2004-12-09 Verwendung von bisaminen zur verstärkung der antimikrobiellen wirkung von wässrigen zusammensetzungen

Country Status (10)

Country Link
US (2) US7445771B2 (de)
EP (2) EP2062872B1 (de)
JP (1) JP4644682B2 (de)
AT (1) ATE428684T1 (de)
AU (1) AU2004297269B2 (de)
CA (1) CA2546381C (de)
DE (1) DE602004020665D1 (de)
DK (1) DK1692092T3 (de)
ES (2) ES2561034T3 (de)
WO (1) WO2005056515A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
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PT1190718E (pt) * 1996-12-13 2006-08-31 Alcon Lab Inc Composicoes oftalmicas contendo aminoalcoois
ES2561034T3 (es) * 2003-12-09 2016-02-24 Novartis Ag Uso de bis-aminas para incrementar la actividad antimicrobiana de composiciones acuosas
TWI394564B (zh) * 2006-09-21 2013-05-01 Alcon Res Ltd 自行保存型水性藥學組成物
US8388941B2 (en) * 2006-09-28 2013-03-05 Alcon Research, Ltd. Self preserved aqueous pharmaceutical compositions
US20080148689A1 (en) * 2006-12-20 2008-06-26 Bausch & Lomb Incorporated Packaging solutions
KR101541303B1 (ko) * 2008-03-17 2015-08-03 알콘 리서치, 리미티드 보레이트-폴리올 복합체를 함유하는 수성 약학적 조성물
EP2424833B1 (de) 2009-04-29 2015-07-29 ANGUS Chemical Company Polyhydroxydiamine als multifunktionelle zusatzstoffe für farben, beschichtungen und epoxide
TWI489997B (zh) * 2009-06-19 2015-07-01 Alcon Res Ltd 含有硼酸-多元醇錯合物之水性藥學組成物
EP2513040B1 (de) 2009-12-17 2016-09-21 ANGUS Chemical Company Aminoalkoholverbindungen, vorläufer sowie verfahren zu ihrer herstellung und verwendung
JP5476358B2 (ja) 2010-12-27 2014-04-23 ダウ グローバル テクノロジーズ エルエルシー 低vocポリアミノアルコール
EP3533780A1 (de) 2011-07-28 2019-09-04 ANGUS Chemical Company Aminoalkoholverbindungen und ihre verwendung als additive mit keinem oder geringem anteil an flüchtigen verbindungen für lacke und beschichtungen
CN103664652A (zh) * 2013-09-25 2014-03-26 南京工业大学 一种n,n,n′,n′-四(2-羟基乙基)-乙二胺的合成方法
CN105801436A (zh) * 2016-04-13 2016-07-27 四川之江高新材料股份有限公司 N,n,n’-三甲基-n’-羟乙基-乙二胺的合成方法

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US2246524A (en) * 1938-08-10 1941-06-24 Monsanto Chemicals Germicide
DE969699C (de) * 1953-07-30 1958-07-10 Ciba Geigy Verfahren zum Faerben und Bedrucken cellulosehaltiger Materialien und fuer dessen Durchfuehrung geeignete Loesungen und Farbstoffpraeparate
US3206462A (en) * 1962-10-31 1965-09-14 Dow Chemical Co Quaternary poly(oxyalkylene)alkylbis(diethylenetriamine) compounds
US3294689A (en) * 1963-10-24 1966-12-27 John S Pierce Synergistic sequestering agent
GB1327315A (en) * 1970-08-17 1973-08-22 Pliva Pharm & Chem Works N,n-bis-hydroxyalkyl- ethylenediamines
US3729564A (en) * 1970-12-16 1973-04-24 Pfizer N-secondary alkyl alkanediamines and derivatives thereof as anti-inflammatory agents
US3855297A (en) * 1971-03-10 1974-12-17 Sterling Drug Inc 1,1{40 -bridged-bis{8 n-(alkyl)-2-aminoethanols{9
DE2113208C3 (de) * 1971-03-18 1974-04-25 Th. Goldschmidt Ag, 4300 Essen Octylaminderivate, deren Herstellung und Verwendung als Bioeide
AT324290B (de) * 1972-06-09 1975-08-25 Pliva Pharm & Chem Works Verfahren zur herstellung von n, n'-bis-(alpha-hydroxyalkyl)-diaminen
US4004030A (en) * 1972-07-11 1977-01-18 Th. Goldschmidt Ag Microbiocidally effective amines or amine mixtures
US4119668A (en) * 1975-06-02 1978-10-10 Sterling Drug Inc. N,N'-Bridged-bis[N,N'substituted-2-hydroxy alkaneammonium] salts
DE2530243C2 (de) * 1975-07-07 1985-03-07 Henkel KGaA, 4000 Düsseldorf Verwendung von N-substituierten Aminoalkanolen als antimikrobielle Wirkstoffe
AU653768B2 (en) 1990-12-27 1994-10-13 Advanced Medical Optics, Inc. Method and composition for disinfecting contact lenses
US5505953A (en) 1992-05-06 1996-04-09 Alcon Laboratories, Inc. Use of borate-polyol complexes in ophthalmic compositions
AU6667894A (en) 1993-04-28 1994-11-21 Alcon Laboratories, Inc. Diamines as antimicrobial agents and use thereof in ophthalmic composition
US5631005A (en) 1994-09-21 1997-05-20 Alcon Laboratories, Inc. Use of amidoamines in ophthalmic compositions
WO1996003158A1 (en) 1994-07-22 1996-02-08 Alcon Laboratories, Inc. Use of low molecular weight amino acids in ophthalmic compositions
AU6519496A (en) * 1995-07-18 1997-02-18 Waters Investments Limited Buffer/additives electrolyte combinations for electrokinetic chromatography
PT1190718E (pt) 1996-12-13 2006-08-31 Alcon Lab Inc Composicoes oftalmicas contendo aminoalcoois
JPH10273403A (ja) * 1997-03-28 1998-10-13 Iwao Hishida 消毒、脱臭、抗菌、抗黴組成物
ZA9811445B (en) 1997-12-19 1999-08-16 Alcon Lab Inc Aminobiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions.
CA2678495C (en) * 2000-09-20 2014-05-27 Lonza Ag Disinfectant composition including quaternary ammonium salt and alkanolamine
CN1477929A (zh) 2000-11-29 2004-02-25 ��˹��ŵ�� 水性消毒系统
JP4905616B2 (ja) * 2001-04-19 2012-03-28 ライオン株式会社 ソフトコンタクトレンズ用点眼剤
JP4801300B2 (ja) * 2001-12-27 2011-10-26 ライオン株式会社 外用液状組成物
JP4524538B2 (ja) * 2002-04-08 2010-08-18 ライオン株式会社 眼科用組成物
ES2561034T3 (es) * 2003-12-09 2016-02-24 Novartis Ag Uso de bis-aminas para incrementar la actividad antimicrobiana de composiciones acuosas

Also Published As

Publication number Publication date
DK1692092T3 (da) 2009-06-22
AU2004297269A1 (en) 2005-06-23
JP4644682B2 (ja) 2011-03-02
DE602004020665D1 (de) 2009-05-28
CA2546381A1 (en) 2005-06-23
JP2007513966A (ja) 2007-05-31
ES2323132T3 (es) 2009-07-07
WO2005056515A3 (en) 2005-12-01
US7445771B2 (en) 2008-11-04
US20090030085A1 (en) 2009-01-29
AU2004297269B2 (en) 2010-11-18
WO2005056515A2 (en) 2005-06-23
EP1692092B1 (de) 2009-04-15
EP2062872A3 (de) 2009-06-17
CA2546381C (en) 2012-11-06
EP2062872A2 (de) 2009-05-27
ES2561034T3 (es) 2016-02-24
US20050154065A1 (en) 2005-07-14
US7871602B2 (en) 2011-01-18
EP1692092A2 (de) 2006-08-23
EP2062872B1 (de) 2015-12-09

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