ATE427316T1 - Verfahren zur reinigung von rohem vancomycin - Google Patents

Verfahren zur reinigung von rohem vancomycin

Info

Publication number
ATE427316T1
ATE427316T1 AT05816363T AT05816363T ATE427316T1 AT E427316 T1 ATE427316 T1 AT E427316T1 AT 05816363 T AT05816363 T AT 05816363T AT 05816363 T AT05816363 T AT 05816363T AT E427316 T1 ATE427316 T1 AT E427316T1
Authority
AT
Austria
Prior art keywords
vancomycin
hydrochloride
vancomycin hydrochloride
impurities
substantially free
Prior art date
Application number
AT05816363T
Other languages
English (en)
Inventor
Rok Grahek
Andrej Bastarda
Original Assignee
Lek Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals filed Critical Lek Pharmaceuticals
Application granted granted Critical
Publication of ATE427316T1 publication Critical patent/ATE427316T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AT05816363T 2004-12-07 2005-12-05 Verfahren zur reinigung von rohem vancomycin ATE427316T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SI200400334A SI21924A (sl) 2004-12-07 2004-12-07 Cist vankomicin hidroklorid

Publications (1)

Publication Number Publication Date
ATE427316T1 true ATE427316T1 (de) 2009-04-15

Family

ID=35583459

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05816363T ATE427316T1 (de) 2004-12-07 2005-12-05 Verfahren zur reinigung von rohem vancomycin

Country Status (9)

Country Link
US (1) US8435938B2 (de)
EP (1) EP1824874B1 (de)
JP (1) JP4729047B2 (de)
AT (1) ATE427316T1 (de)
DE (1) DE602005013691D1 (de)
ES (1) ES2322961T3 (de)
PL (1) PL1824874T3 (de)
SI (2) SI21924A (de)
WO (1) WO2006061166A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1798237A1 (de) 2005-12-16 2007-06-20 Pharmatex Italia Srl Prozess zur Reinigung von Makrolid-Antibiotika
KR101101663B1 (ko) * 2009-01-13 2011-12-30 (주) 제노텍 반코마이신 습체의 정제방법
CN104610434B (zh) * 2013-11-01 2019-06-07 浙江医药股份有限公司新昌制药厂 一种盐酸万古霉素的分离纯化方法
EP3866829A1 (de) * 2018-10-15 2021-08-25 Savara Inc. Trennung von vancomycin und seinen abbauprodukten
CN113544137A (zh) * 2019-03-14 2021-10-22 浙江医药股份有限公司新昌制药厂 一种万古霉素类似物的分离纯化方法
CN114112612A (zh) * 2021-10-28 2022-03-01 丽珠集团福州福兴医药有限公司 一种替考拉宁i5杂质的分离纯化方法及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI844801L (fi) * 1983-12-12 1985-06-13 Lilly Co Eli Foerbaettring vid rening av vankomycin och reningsprodukt.
JPH0260598A (ja) * 1988-08-22 1990-03-01 Glaxo Group Ltd 抗生物質の製造
US5149784A (en) * 1990-07-10 1992-09-22 Abbott Laboratories Process for making vancomycin
US5258495A (en) * 1990-07-10 1993-11-02 Abbott Laboratories Process for making vancomycin HC1
SI9500040B (sl) 1995-02-07 2002-02-28 Lek, Kromatografsko čiščenje Vankomicin hidroklorida z uporabo preparativne HPLC
EP1025852A4 (de) * 1997-10-03 2001-11-07 Fujisawa Pharmaceutical Co Hydrochloride von vancomycin-antibiotika sowie verfahren zu deren herstellung
CN1415758A (zh) * 2001-10-30 2003-05-07 上海医药工业研究院 盐酸万古霉素原料生产工艺
KR100554481B1 (ko) * 2004-06-30 2006-03-03 씨제이 주식회사 반코마이신 염산염의 정제방법

Also Published As

Publication number Publication date
PL1824874T3 (pl) 2009-08-31
ES2322961T3 (es) 2009-07-02
EP1824874A1 (de) 2007-08-29
SI1824874T1 (sl) 2009-08-31
DE602005013691D1 (de) 2009-05-14
US20100190958A1 (en) 2010-07-29
US8435938B2 (en) 2013-05-07
JP2008523003A (ja) 2008-07-03
JP4729047B2 (ja) 2011-07-20
EP1824874B1 (de) 2009-04-01
WO2006061166A1 (en) 2006-06-15
SI21924A (sl) 2006-06-30

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