HK1217204A1 - 達托霉素純化的過程 - Google Patents

達托霉素純化的過程

Info

Publication number
HK1217204A1
HK1217204A1 HK16104925.4A HK16104925A HK1217204A1 HK 1217204 A1 HK1217204 A1 HK 1217204A1 HK 16104925 A HK16104925 A HK 16104925A HK 1217204 A1 HK1217204 A1 HK 1217204A1
Authority
HK
Hong Kong
Prior art keywords
discloses
daptomycin
micelles
purifying
anion exchange
Prior art date
Application number
HK16104925.4A
Other languages
English (en)
Inventor
Thomas J Kelleher
Jan-Ji Lai
Joseph P Decourcey
Maurizio Zenoni
Auro R Tagliani
Original Assignee
Cubist Pharmaceuticals Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26873002&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1217204(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cubist Pharmaceuticals Llc filed Critical Cubist Pharmaceuticals Llc
Publication of HK1217204A1 publication Critical patent/HK1217204A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/145Extraction; Separation; Purification by extraction or solubilisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/20Partition-, reverse-phase or hydrophobic interaction chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces
HK16104925.4A 2000-01-20 2016-04-29 達托霉素純化的過程 HK1217204A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17717000P 2000-01-20 2000-01-20
US09/735,191 US6696412B1 (en) 2000-01-20 2000-11-28 High purity lipopeptides, Lipopeptide micelles and processes for preparing same

Publications (1)

Publication Number Publication Date
HK1217204A1 true HK1217204A1 (zh) 2016-12-30

Family

ID=26873002

Family Applications (6)

Application Number Title Priority Date Filing Date
HK03106508.9A HK1054240A1 (zh) 2000-01-20 2003-09-11 高純度脂肽、脂肽膠束及其製備方法
HK06104688.3A HK1085746A1 (en) 2000-01-20 2006-04-19 Process for the purification of daptomycin
HK09101340.6A HK1120528A1 (en) 2000-01-20 2009-02-12 High purity lipopeptides, lipopeptide micelles and processes for preparing same
HK11105628.6A HK1151546A1 (zh) 2000-01-20 2011-06-07 高純度脂肽、脂肽膠束及其製備方法
HK16104932.5A HK1217205A1 (zh) 2000-01-20 2016-04-29 高純度脂肽、脂肽膠束及其製備方法
HK16104925.4A HK1217204A1 (zh) 2000-01-20 2016-04-29 達托霉素純化的過程

Family Applications Before (5)

Application Number Title Priority Date Filing Date
HK03106508.9A HK1054240A1 (zh) 2000-01-20 2003-09-11 高純度脂肽、脂肽膠束及其製備方法
HK06104688.3A HK1085746A1 (en) 2000-01-20 2006-04-19 Process for the purification of daptomycin
HK09101340.6A HK1120528A1 (en) 2000-01-20 2009-02-12 High purity lipopeptides, lipopeptide micelles and processes for preparing same
HK11105628.6A HK1151546A1 (zh) 2000-01-20 2011-06-07 高純度脂肽、脂肽膠束及其製備方法
HK16104932.5A HK1217205A1 (zh) 2000-01-20 2016-04-29 高純度脂肽、脂肽膠束及其製備方法

Country Status (25)

Country Link
US (7) US6696412B1 (zh)
EP (6) EP2264047B1 (zh)
JP (2) JP5303087B2 (zh)
KR (4) KR20110126737A (zh)
CN (5) CN101240013B (zh)
AT (2) ATE311405T1 (zh)
AU (1) AU784937B2 (zh)
BR (1) BRPI0107731B8 (zh)
CA (2) CA2398726C (zh)
CY (2) CY1109846T1 (zh)
CZ (2) CZ307877B6 (zh)
DE (2) DE60140631D1 (zh)
DK (2) DK1586580T3 (zh)
ES (4) ES2799702T3 (zh)
HK (6) HK1054240A1 (zh)
HU (1) HUP0203969A2 (zh)
IL (3) IL150733A0 (zh)
IS (1) IS6470A (zh)
MX (1) MXPA02007132A (zh)
NO (1) NO20023476L (zh)
NZ (1) NZ520324A (zh)
PL (3) PL226956B1 (zh)
PT (2) PT2264047E (zh)
RU (1) RU2311460C9 (zh)
WO (1) WO2001053330A2 (zh)

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* Cited by examiner, † Cited by third party
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RU2348647C2 (ru) 2001-08-06 2009-03-10 Кьюбист Фармасьютикалз, Инк Новые депсипептиды и способы их получения
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WO2011002258A2 (ko) * 2009-07-02 2011-01-06 한양대학교 산학협력단 아르기닌 기제 양친성 펩티드 마이셀
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CN112684043A (zh) * 2020-12-16 2021-04-20 南京健友生化制药股份有限公司 一种达托霉素有关物质的检测方法
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