ATE426159T1 - Helicobacter pylori nap protein - Google Patents

Helicobacter pylori nap protein

Info

Publication number
ATE426159T1
ATE426159T1 AT99911992T AT99911992T ATE426159T1 AT E426159 T1 ATE426159 T1 AT E426159T1 AT 99911992 T AT99911992 T AT 99911992T AT 99911992 T AT99911992 T AT 99911992T AT E426159 T1 ATE426159 T1 AT E426159T1
Authority
AT
Austria
Prior art keywords
nap
helicobacter pylori
pylori
proteins
processes
Prior art date
Application number
AT99911992T
Other languages
English (en)
Inventor
Guido Grandi
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of ATE426159T1 publication Critical patent/ATE426159T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT99911992T 1998-04-08 1999-04-07 Helicobacter pylori nap protein ATE426159T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9807721.7A GB9807721D0 (en) 1998-04-08 1998-04-08 Antigen

Publications (1)

Publication Number Publication Date
ATE426159T1 true ATE426159T1 (de) 2009-04-15

Family

ID=10830180

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99911992T ATE426159T1 (de) 1998-04-08 1999-04-07 Helicobacter pylori nap protein

Country Status (11)

Country Link
US (1) US7038012B1 (de)
EP (1) EP1068522B1 (de)
JP (2) JP3626684B2 (de)
AT (1) ATE426159T1 (de)
AU (1) AU3048999A (de)
CA (1) CA2326413C (de)
DE (1) DE69940595D1 (de)
ES (1) ES2322213T3 (de)
GB (1) GB9807721D0 (de)
PT (1) PT1068522E (de)
WO (1) WO1999053310A1 (de)

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US7141244B1 (en) * 1992-03-02 2006-11-28 Chiron Srl Helicobacter pylori proteins useful for vaccines and diagnostics
DE69529219T2 (de) * 1994-07-01 2003-11-06 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Helicobacter proteine und impstoffe
GB2324093A (en) * 1996-01-04 1998-10-14 Rican Limited Helicobacter pylori bacterioferritin
GB9807721D0 (en) * 1998-04-08 1998-06-10 Chiron Spa Antigen
CA2871789C (en) 2000-01-17 2017-04-04 Novartis Vaccines And Diagnostics S.R.L. Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins
AU2002303330B2 (en) 2001-05-31 2008-07-24 Novartis Vaccines And Diagnostics, Inc. Chimeric alphavirus replicon particles
GB0118249D0 (en) 2001-07-26 2001-09-19 Chiron Spa Histidine vaccines
GB0121591D0 (en) 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
US7501134B2 (en) 2002-02-20 2009-03-10 Novartis Vaccines And Diagnostics, Inc. Microparticles with adsorbed polypeptide-containing molecules
AU2003233008B2 (en) * 2002-04-22 2008-04-24 Recopharma Ab Fusion polypeptides and methods for inhibiting microbial adhesion
MXPA05004528A (es) 2002-11-01 2005-07-26 Glaxosmithkline Biolog Sa Composicion inmunogenica.
AU2003299994A1 (en) 2002-12-27 2004-07-29 Chiron Corporation Immunogenic compositions containing phospholpid
EP2258365B1 (de) 2003-03-28 2013-05-29 Novartis Vaccines and Diagnostics, Inc. Verwendung von organischen verbindungen zur immunstärkung
US7191698B2 (en) 2003-04-03 2007-03-20 Battelle Memorial Institute System and technique for ultrasonic determination of degree of cooking
JP5557415B2 (ja) 2003-06-02 2014-07-23 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド 吸着させたトキソイドおよび多糖類含有抗原を含む微粒子に基づく免疫原性組成物
WO2006115509A2 (en) 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Small molecule immunopotentiators and assays for their detection
CA2571421A1 (en) 2004-06-24 2006-01-05 Nicholas Valiante Compounds for immunopotentiation
US20060165716A1 (en) 2004-07-29 2006-07-27 Telford John L Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae
ATE431156T1 (de) * 2005-09-23 2009-05-15 Prete Gianfranco Del Verwendung des neutrophil-activating-protein von helicobacter pylori und/oder teile davon als adjuvant für die induktion einer t-helper type 1 (th1) immunantwort
CA2626253A1 (en) 2005-10-18 2007-04-26 Novartis Vaccines And Diagnostics, Inc. Mucosal and systemic immunizations with alphavirus replicon particles
AU2006335256B2 (en) 2005-11-22 2012-10-18 Novartis Vaccines And Diagnostics, Inc. Norovirus and sapovirus antigens
WO2007109813A1 (en) 2006-03-23 2007-09-27 Novartis Ag Imidazoquinoxaline compounds as immunomodulators
CA2699513C (en) 2007-09-12 2018-03-13 Novartis Ag Gas57 mutant antigens and gas57 antibodies
BRPI0821240B8 (pt) 2007-12-21 2022-10-04 Novartis Ag formas mutantes de estreptolisina o
CN102481349B (zh) 2009-01-12 2014-10-15 诺华股份有限公司 抗革兰氏阳性细菌疫苗中的Cna_B结构域
CN102933267B (zh) 2010-05-28 2015-05-27 泰特里斯在线公司 交互式混合异步计算机游戏基础结构
TWI432579B (zh) 2012-01-20 2014-04-01 Nat Univ Tsing Hua 單步驟純化重組胃幽門螺旋桿菌嗜中性白血球激活蛋白（ｈｐ－ｎａｐ）的方法
CN111676265B (zh) * 2020-05-29 2021-06-15 威海市立医院 一种中性粒细胞的吞噬能力的检测方法

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JPS57132880A (en) * 1981-02-10 1982-08-17 Banyu Pharmaceut Co Ltd Preparation of choline oxidase by fermentation method
US4724208A (en) * 1985-11-04 1988-02-09 Miles Laboratories, Inc. Process for the production of solution stable alpha-amylase and liquid alpha-amylase produced thereby
ATA901588A (de) * 1987-11-19 1994-07-15 Sandoz Ag Von humanmonozyten abgeleiteter neutrophilenaktivierungsfaktor (naf) und verfahren zu seiner herstellung
JP3051160B2 (ja) * 1988-12-08 2000-06-12 ノバルティス・アクチエンゲゼルシャフト 好中球活性化ペプチド‐２
US5079228A (en) * 1990-02-05 1992-01-07 Board Of Regents, The University Of Texas System Peptide inhibitors of neutrophil activating factor induced chemotaxis
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WO1992001273A1 (en) 1990-07-09 1992-01-23 Computer Detection Systems Pty. Ltd. Automatic dispensing and recording system
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US6290962B1 (en) * 1992-11-03 2001-09-18 Oravax, Inc. Urease-based vaccine and treatment for helicobacter infection
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US5780040A (en) * 1994-06-08 1998-07-14 Tufts University School Of Medicine Hospital, Inc. Helicobacter pylori nickel binding protein
DE69529219T2 (de) * 1994-07-01 2003-11-06 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Helicobacter proteine und impstoffe
GB2324093A (en) * 1996-01-04 1998-10-14 Rican Limited Helicobacter pylori bacterioferritin
US5907035A (en) * 1996-05-23 1999-05-25 Baxter Biotech Technology Sarl Aqueous two-phase metal affinity partitioning protein purification system
JP2001509167A (ja) * 1997-01-24 2001-07-10 エイブイアイ バイオファーマ，インコーポレイテッド Ｈ．ｐｙｌｏｒｉ感染を処置するための方法および結合体
EP0887403A3 (de) * 1997-06-27 2000-12-06 Chiron S.P.A. Abgeschwächte Stämme von Vibrio cholerae
GB9807721D0 (en) * 1998-04-08 1998-06-10 Chiron Spa Antigen
EP1073745B1 (de) * 1998-04-30 2004-12-01 Chiron S.r.l. Verfahren zur immunisierung und behandlung von h. pylori infektion
JP2000200838A (ja) * 1998-10-30 2000-07-18 Seiko Epson Corp 半導体記憶装置およびその製造方法
EP1221968B1 (de) * 1999-10-13 2010-01-13 Novartis Vaccines and Diagnostics, Inc. Verfahren zur erhaltung zellimmuneantworten gegen proteinen

Also Published As

Publication number Publication date
PT1068522E (pt) 2009-06-04
DE69940595D1 (en) 2009-04-30
WO1999053310A1 (en) 1999-10-21
JP2002511492A (ja) 2002-04-16
US7038012B1 (en) 2006-05-02
CA2326413C (en) 2007-10-16
JP3626684B2 (ja) 2005-03-09
ES2322213T3 (es) 2009-06-17
CA2326413A1 (en) 1999-10-21
EP1068522A1 (de) 2001-01-17
AU3048999A (en) 1999-11-01
EP1068522B1 (de) 2009-03-18
JP2005097311A (ja) 2005-04-14
GB9807721D0 (en) 1998-06-10

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