ATE426159T1 - Helicobacter pylori nap protein - Google Patents

Helicobacter pylori nap protein

Info

Publication number
ATE426159T1
ATE426159T1 AT99911992T AT99911992T ATE426159T1 AT E426159 T1 ATE426159 T1 AT E426159T1 AT 99911992 T AT99911992 T AT 99911992T AT 99911992 T AT99911992 T AT 99911992T AT E426159 T1 ATE426159 T1 AT E426159T1
Authority
AT
Austria
Prior art keywords
nap
helicobacter pylori
pylori
proteins
processes
Prior art date
Application number
AT99911992T
Other languages
English (en)
Inventor
Guido Grandi
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of ATE426159T1 publication Critical patent/ATE426159T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT99911992T 1998-04-08 1999-04-07 Helicobacter pylori nap protein ATE426159T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9807721.7A GB9807721D0 (en) 1998-04-08 1998-04-08 Antigen

Publications (1)

Publication Number Publication Date
ATE426159T1 true ATE426159T1 (de) 2009-04-15

Family

ID=10830180

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99911992T ATE426159T1 (de) 1998-04-08 1999-04-07 Helicobacter pylori nap protein

Country Status (11)

Country Link
US (1) US7038012B1 (de)
EP (1) EP1068522B1 (de)
JP (2) JP3626684B2 (de)
AT (1) ATE426159T1 (de)
AU (1) AU3048999A (de)
CA (1) CA2326413C (de)
DE (1) DE69940595D1 (de)
ES (1) ES2322213T3 (de)
GB (1) GB9807721D0 (de)
PT (1) PT1068522E (de)
WO (1) WO1999053310A1 (de)

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US7141244B1 (en) * 1992-03-02 2006-11-28 Chiron Srl Helicobacter pylori proteins useful for vaccines and diagnostics
ATE229978T1 (de) * 1994-07-01 2003-01-15 Chiron Corp Helicobacter proteine und impstoffe
ES2283012T3 (es) * 1996-01-04 2007-10-16 Novartis Vaccines And Diagnostics, Inc. Bacterioferritina de helicobacter pylori.
GB9807721D0 (en) * 1998-04-08 1998-06-10 Chiron Spa Antigen
PT2289545T (pt) 2000-01-17 2016-09-06 Glaxosmithkline Biologicals Sa Vacina de omv suplementada contra meningococos
EP1399183B1 (de) 2001-05-31 2010-06-30 Novartis Vaccines and Diagnostics, Inc. Chimere alphavirus-replikon-partikel
GB0118249D0 (en) 2001-07-26 2001-09-19 Chiron Spa Histidine vaccines
GB0121591D0 (en) 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
US7501134B2 (en) 2002-02-20 2009-03-10 Novartis Vaccines And Diagnostics, Inc. Microparticles with adsorbed polypeptide-containing molecules
CA2483476A1 (en) * 2002-04-22 2003-10-30 Absorber, Ab Fusion polypeptides and methods for inhibiting microbial adhesion
ES2649048T3 (es) 2002-11-01 2018-01-09 Glaxosmithkline Biologicals S.A. Procedimiento de secado
JP2006520746A (ja) 2002-12-27 2006-09-14 カイロン コーポレイション リン脂質を含む免疫原性組成物
CA2520124A1 (en) 2003-03-28 2004-10-14 Chiron Corporation Use of benzazole compounds for immunopotentiation
US7191698B2 (en) 2003-04-03 2007-03-20 Battelle Memorial Institute System and technique for ultrasonic determination of degree of cooking
PL1631264T5 (pl) 2003-06-02 2018-09-28 Glaxosmithkline Biologicals Sa Kompozycje immunogenne oparte na biodegradowalnych mikrocząstkach zawierających toksoid błonicy i tężca
WO2006115509A2 (en) 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Small molecule immunopotentiators and assays for their detection
WO2006002422A2 (en) 2004-06-24 2006-01-05 Novartis Vaccines And Diagnostics Inc. Compounds for immunopotentiation
EP2612679A1 (de) 2004-07-29 2013-07-10 Novartis Vaccines and Diagnostics, Inc. Immunogene Zusammensetzungen für grampositive Bakterien wie etwa Streptococcus agalactiae
EP1767214B1 (de) * 2005-09-23 2009-05-13 Gianfranco Del Prete Verwendung des Neutrophil-activating-protein von Helicobacter pylori und/oder Teile davon als Adjuvant für die Induktion einer T-helper type 1 (TH1) Immunantwort
EP2357000A1 (de) 2005-10-18 2011-08-17 Novartis Vaccines and Diagnostics, Inc. Mukosale und systemische Immunisierungen mit Alphavirus-Replikonpartikeln
WO2007081447A2 (en) 2005-11-22 2007-07-19 Novartis Vaccines And Diagnostics, Inc. Norovirus and sapovirus antigens
ES2536426T3 (es) 2006-03-23 2015-05-25 Novartis Ag Compuestos de imidazoquinoxalina como inmunomoduladores
KR101621837B1 (ko) 2007-09-12 2016-05-17 노파르티스 아게 Ｇａｓ57 돌연변이 항원 및 ｇａｓ57 항체
CN104292312A (zh) 2007-12-21 2015-01-21 诺华股份有限公司 链球菌溶血素o的突变形式
US8585505B2 (en) 2008-12-15 2013-11-19 Tetris Online, Inc. Inter-game interactive hybrid asynchronous computer game infrastructure
AU2010204139A1 (en) 2009-01-12 2011-08-11 Novartis Ag Cna_B domain antigens in vaccines against gram positive bacteria
TWI432579B (zh) 2012-01-20 2014-04-01 Nat Univ Tsing Hua 單步驟純化重組胃幽門螺旋桿菌嗜中性白血球激活蛋白（ｈｐ－ｎａｐ）的方法
CN111676265B (zh) * 2020-05-29 2021-06-15 威海市立医院 一种中性粒细胞的吞噬能力的检测方法

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JPS57132880A (en) * 1981-02-10 1982-08-17 Banyu Pharmaceut Co Ltd Preparation of choline oxidase by fermentation method
US4724208A (en) * 1985-11-04 1988-02-09 Miles Laboratories, Inc. Process for the production of solution stable alpha-amylase and liquid alpha-amylase produced thereby
NL194982C (nl) * 1987-11-19 2003-04-10 Novartis Ag Neutrofiel-activerende factor (NAF) in geïsoleerde vorm, werkwijze voor het bereiden van NAF, expressievector met een codering voor NAF en een NAF bevattend farmaceutisch preparaat.
AU634508B2 (en) * 1988-12-08 1993-02-25 Sandoz Ag Neutrophil-activating peptide-2
US5079228A (en) * 1990-02-05 1992-01-07 Board Of Regents, The University Of Texas System Peptide inhibitors of neutrophil activating factor induced chemotaxis
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WO1992001273A1 (en) 1990-07-09 1992-01-23 Computer Detection Systems Pty. Ltd. Automatic dispensing and recording system
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US5646016A (en) * 1991-02-06 1997-07-08 Genetics Institute, Inc. Peptide and protein fusions to thioredoxin, thioredoxin-like molecules, and modified thioredoxin-like molecules
AU3728293A (en) * 1992-02-26 1993-09-13 Vanderbilt University Purified vacuolating toxin from (helicobacter) pylori and methods to use same
US5972336A (en) * 1992-11-03 1999-10-26 Oravax Merieux Co. Urease-based vaccine against helicobacter infection
US6290962B1 (en) * 1992-11-03 2001-09-18 Oravax, Inc. Urease-based vaccine and treatment for helicobacter infection
US5780040A (en) * 1994-06-08 1998-07-14 Tufts University School Of Medicine Hospital, Inc. Helicobacter pylori nickel binding protein
ATE229978T1 (de) * 1994-07-01 2003-01-15 Chiron Corp Helicobacter proteine und impstoffe
ES2283012T3 (es) * 1996-01-04 2007-10-16 Novartis Vaccines And Diagnostics, Inc. Bacterioferritina de helicobacter pylori.
US5907035A (en) * 1996-05-23 1999-05-25 Baxter Biotech Technology Sarl Aqueous two-phase metal affinity partitioning protein purification system
CA2278924A1 (en) * 1997-01-24 1998-07-30 Avi Biopharma, Inc. Method and conjugate for treating h. pylori infection
EP0887403A3 (de) * 1997-06-27 2000-12-06 Chiron S.P.A. Abgeschwächte Stämme von Vibrio cholerae
GB9807721D0 (en) * 1998-04-08 1998-06-10 Chiron Spa Antigen
WO1999057278A2 (en) * 1998-04-30 1999-11-11 Chiron S.P.A. IMMUNIZATION AGAINST AND TREATMENT FOR INFECTION BY $i(H.PYLORI)
JP2000200838A (ja) * 1998-10-30 2000-07-18 Seiko Epson Corp 半導体記憶装置およびその製造方法
PT1221968E (pt) * 1999-10-13 2010-04-16 Novartis Vaccines & Diagnostic Processo de obtenção de respostas imunes celulares de proteínas

Also Published As

Publication number Publication date
JP2002511492A (ja) 2002-04-16
US7038012B1 (en) 2006-05-02
DE69940595D1 (en) 2009-04-30
GB9807721D0 (en) 1998-06-10
EP1068522A1 (de) 2001-01-17
AU3048999A (en) 1999-11-01
JP2005097311A (ja) 2005-04-14
WO1999053310A1 (en) 1999-10-21
ES2322213T3 (es) 2009-06-17
CA2326413C (en) 2007-10-16
EP1068522B1 (de) 2009-03-18
CA2326413A1 (en) 1999-10-21
PT1068522E (pt) 2009-06-04
JP3626684B2 (ja) 2005-03-09

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