ATE426159T1 - Helicobacter pylori nap protein - Google Patents

Helicobacter pylori nap protein

Info

Publication number
ATE426159T1
ATE426159T1 AT99911992T AT99911992T ATE426159T1 AT E426159 T1 ATE426159 T1 AT E426159T1 AT 99911992 T AT99911992 T AT 99911992T AT 99911992 T AT99911992 T AT 99911992T AT E426159 T1 ATE426159 T1 AT E426159T1
Authority
AT
Austria
Prior art keywords
nap
helicobacter pylori
pylori
proteins
processes
Prior art date
Application number
AT99911992T
Other languages
English (en)
Inventor
Guido Grandi
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of ATE426159T1 publication Critical patent/ATE426159T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT99911992T 1998-04-08 1999-04-07 Helicobacter pylori nap protein ATE426159T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9807721.7A GB9807721D0 (en) 1998-04-08 1998-04-08 Antigen

Publications (1)

Publication Number Publication Date
ATE426159T1 true ATE426159T1 (de) 2009-04-15

Family

ID=10830180

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99911992T ATE426159T1 (de) 1998-04-08 1999-04-07 Helicobacter pylori nap protein

Country Status (11)

Country Link
US (1) US7038012B1 (de)
EP (1) EP1068522B1 (de)
JP (2) JP3626684B2 (de)
AT (1) ATE426159T1 (de)
AU (1) AU3048999A (de)
CA (1) CA2326413C (de)
DE (1) DE69940595D1 (de)
ES (1) ES2322213T3 (de)
GB (1) GB9807721D0 (de)
PT (1) PT1068522E (de)
WO (1) WO1999053310A1 (de)

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US7141244B1 (en) * 1992-03-02 2006-11-28 Chiron Srl Helicobacter pylori proteins useful for vaccines and diagnostics
ATE229978T1 (de) * 1994-07-01 2003-01-15 Chiron Corp Helicobacter proteine und impstoffe
DK0909323T3 (da) 1996-01-04 2007-05-21 Novartis Vaccines & Diagnostic Helicobacter pylori-bakterioferritin
GB9807721D0 (en) * 1998-04-08 1998-06-10 Chiron Spa Antigen
CA2871789C (en) 2000-01-17 2017-04-04 Novartis Vaccines And Diagnostics S.R.L. Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins
JP4608210B2 (ja) 2001-05-31 2011-01-12 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド キメラアルファウイルスレプリコン粒子
GB0118249D0 (en) 2001-07-26 2001-09-19 Chiron Spa Histidine vaccines
GB0121591D0 (en) 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
WO2003070909A2 (en) 2002-02-20 2003-08-28 Chiron Corporation Microparticles with adsorbed polypeptide-containing molecules
AU2003233008B2 (en) * 2002-04-22 2008-04-24 Recopharma Ab Fusion polypeptides and methods for inhibiting microbial adhesion
DK1556477T3 (en) 2002-11-01 2017-10-23 Glaxosmithkline Biologicals Sa Process for drying
AU2003299994A1 (en) 2002-12-27 2004-07-29 Chiron Corporation Immunogenic compositions containing phospholpid
ES2423800T3 (es) 2003-03-28 2013-09-24 Novartis Vaccines And Diagnostics, Inc. Uso de compuestos orgánicos para la inmunopotenciación
US7191698B2 (en) 2003-04-03 2007-03-20 Battelle Memorial Institute System and technique for ultrasonic determination of degree of cooking
CA2528007C (en) 2003-06-02 2012-03-27 Chiron Corporation Immunogenic compositions based on microparticles comprising adsorbed toxoid and a polysaccharide-containing antigen
WO2006002422A2 (en) 2004-06-24 2006-01-05 Novartis Vaccines And Diagnostics Inc. Compounds for immunopotentiation
US20110104186A1 (en) 2004-06-24 2011-05-05 Nicholas Valiante Small molecule immunopotentiators and assays for their detection
US20090317420A1 (en) 2004-07-29 2009-12-24 Chiron Corporation Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae
ATE431156T1 (de) * 2005-09-23 2009-05-15 Prete Gianfranco Del Verwendung des neutrophil-activating-protein von helicobacter pylori und/oder teile davon als adjuvant für die induktion einer t-helper type 1 (th1) immunantwort
JP2009511636A (ja) 2005-10-18 2009-03-19 ノバルティス ヴァクシンズ アンド ダイアグノスティクス， インコーポレイテッド アルファウイルスレプリコン粒子による粘膜免疫および全身免疫
JP5215865B2 (ja) 2005-11-22 2013-06-19 ノバルティス ヴァクシンズ アンド ダイアグノスティクス インコーポレイテッド ノロウイルス抗原およびサポウイルス抗原
WO2007109813A1 (en) 2006-03-23 2007-09-27 Novartis Ag Imidazoquinoxaline compounds as immunomodulators
US8287885B2 (en) 2007-09-12 2012-10-16 Novartis Ag GAS57 mutant antigens and GAS57 antibodies
AU2008339551B2 (en) 2007-12-21 2013-10-24 Glaxosmithkline Biologicals S.A. Mutant forms of streptolysin O
AU2010204139A1 (en) 2009-01-12 2011-08-11 Novartis Ag Cna_B domain antigens in vaccines against gram positive bacteria
JP2013532008A (ja) 2010-05-28 2013-08-15 テトリス オンライン インコーポレイテッド 対話式ハイブリッド非同期コンピュータ・ゲーム・インフラストラクチャ
TWI432579B (zh) 2012-01-20 2014-04-01 Nat Univ Tsing Hua 單步驟純化重組胃幽門螺旋桿菌嗜中性白血球激活蛋白（ｈｐ－ｎａｐ）的方法
CN111676265B (zh) * 2020-05-29 2021-06-15 威海市立医院 一种中性粒细胞的吞噬能力的检测方法

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JPS57132880A (en) * 1981-02-10 1982-08-17 Banyu Pharmaceut Co Ltd Preparation of choline oxidase by fermentation method
US4724208A (en) * 1985-11-04 1988-02-09 Miles Laboratories, Inc. Process for the production of solution stable alpha-amylase and liquid alpha-amylase produced thereby
JP3133305B2 (ja) * 1987-11-19 2001-02-05 ノバルティス・アクチエンゲゼルシャフト 好中球活性化因子
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US5079228A (en) * 1990-02-05 1992-01-07 Board Of Regents, The University Of Texas System Peptide inhibitors of neutrophil activating factor induced chemotaxis
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WO1992001273A1 (en) 1990-07-09 1992-01-23 Computer Detection Systems Pty. Ltd. Automatic dispensing and recording system
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DE69333585T2 (de) * 1992-02-26 2005-07-28 Vanderbilt University, Nashville Gereinigtes vakuolisierendes toxin aus helicobacter pylori und methoden zu dessen verwendung
US5972336A (en) * 1992-11-03 1999-10-26 Oravax Merieux Co. Urease-based vaccine against helicobacter infection
US6290962B1 (en) * 1992-11-03 2001-09-18 Oravax, Inc. Urease-based vaccine and treatment for helicobacter infection
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ATE229978T1 (de) * 1994-07-01 2003-01-15 Chiron Corp Helicobacter proteine und impstoffe
DK0909323T3 (da) * 1996-01-04 2007-05-21 Novartis Vaccines & Diagnostic Helicobacter pylori-bakterioferritin
US5907035A (en) * 1996-05-23 1999-05-25 Baxter Biotech Technology Sarl Aqueous two-phase metal affinity partitioning protein purification system
EP0973886B1 (de) * 1997-01-24 2005-03-23 AVI BioPharm, Inc. Verfahren und konjugat zur behandlung von helicobacter pylori-infektionen
EP0887403A3 (de) * 1997-06-27 2000-12-06 Chiron S.P.A. Abgeschwächte Stämme von Vibrio cholerae
GB9807721D0 (en) * 1998-04-08 1998-06-10 Chiron Spa Antigen
DE69922364T2 (de) * 1998-04-30 2005-11-03 Chiron S.R.L. Verfahren zur Immunisierung gegen und zur Behandlung von Infektionen durch H.pylori
JP2000200838A (ja) * 1998-10-30 2000-07-18 Seiko Epson Corp 半導体記憶装置およびその製造方法
US6534064B1 (en) * 1999-10-13 2003-03-18 Chiron Corporation Stabilized protein particles for inducing cellular immune responses

Also Published As

Publication number Publication date
DE69940595D1 (en) 2009-04-30
WO1999053310A1 (en) 1999-10-21
JP3626684B2 (ja) 2005-03-09
JP2005097311A (ja) 2005-04-14
PT1068522E (pt) 2009-06-04
EP1068522A1 (de) 2001-01-17
ES2322213T3 (es) 2009-06-17
CA2326413C (en) 2007-10-16
EP1068522B1 (de) 2009-03-18
CA2326413A1 (en) 1999-10-21
GB9807721D0 (en) 1998-06-10
JP2002511492A (ja) 2002-04-16
US7038012B1 (en) 2006-05-02
AU3048999A (en) 1999-11-01

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