ATE424164T1 - Verfahren zur herstellung einer gefässprothese - Google Patents
Verfahren zur herstellung einer gefässprotheseInfo
- Publication number
- ATE424164T1 ATE424164T1 AT99927195T AT99927195T ATE424164T1 AT E424164 T1 ATE424164 T1 AT E424164T1 AT 99927195 T AT99927195 T AT 99927195T AT 99927195 T AT99927195 T AT 99927195T AT E424164 T1 ATE424164 T1 AT E424164T1
- Authority
- AT
- Austria
- Prior art keywords
- graft prostheses
- producing
- bioengineered graft
- vascular prosthesis
- prepared
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000002792 vascular Effects 0.000 title 1
- 239000000463 material Substances 0.000 abstract 2
- 238000002513 implantation Methods 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3695—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the function or physical properties of the final product, where no specific conditions are defined to achieve this
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3629—Intestinal tissue, e.g. small intestinal submucosa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C53/00—Shaping by bending, folding, twisting, straightening or flattening; Apparatus therefor
- B29C53/36—Bending and joining, e.g. for making hollow articles
- B29C53/38—Bending and joining, e.g. for making hollow articles by bending sheets or strips at right angles to the longitudinal axis of the article being formed and joining the edges
- B29C53/40—Bending and joining, e.g. for making hollow articles by bending sheets or strips at right angles to the longitudinal axis of the article being formed and joining the edges for articles of definite length, i.e. discrete articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C53/00—Shaping by bending, folding, twisting, straightening or flattening; Apparatus therefor
- B29C53/56—Winding and joining, e.g. winding spirally
- B29C53/562—Winding and joining, e.g. winding spirally spirally
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Materials Engineering (AREA)
- General Chemical & Material Sciences (AREA)
- Composite Materials (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Vascular Medicine (AREA)
- Biophysics (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8819898P | 1998-06-05 | 1998-06-05 | |
| US12054799P | 1999-02-17 | 1999-02-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE424164T1 true ATE424164T1 (de) | 2009-03-15 |
Family
ID=26778405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99927195T ATE424164T1 (de) | 1998-06-05 | 1999-06-04 | Verfahren zur herstellung einer gefässprothese |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7121999B2 (enExample) |
| EP (1) | EP1082071B1 (enExample) |
| JP (1) | JP4606583B2 (enExample) |
| AT (1) | ATE424164T1 (enExample) |
| AU (1) | AU754838B2 (enExample) |
| CA (1) | CA2334364C (enExample) |
| DE (1) | DE69940504D1 (enExample) |
| ES (1) | ES2323661T3 (enExample) |
| MX (1) | MXPA00012062A (enExample) |
| WO (1) | WO1999063051A2 (enExample) |
Families Citing this family (79)
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|---|---|---|---|---|
| US6334872B1 (en) | 1994-02-18 | 2002-01-01 | Organogenesis Inc. | Method for treating diseased or damaged organs |
| US20020095218A1 (en) | 1996-03-12 | 2002-07-18 | Carr Robert M. | Tissue repair fabric |
| ATE424147T1 (de) | 1998-06-05 | 2009-03-15 | Organogenesis Inc | Biotechnisch erzeugte gefässprothese für die implantation |
| WO1999062424A2 (en) | 1998-06-05 | 1999-12-09 | Organogenesis Inc. | Bioengineered tubular graft prostheses |
| EP1082071B1 (en) | 1998-06-05 | 2009-03-04 | Organogenesis Inc. | Method of preparing a vascular prosthesis |
| US6773723B1 (en) * | 2000-08-30 | 2004-08-10 | Depuy Acromed, Inc. | Collagen/polysaccharide bilayer matrix |
| EP1320390A2 (en) * | 2000-09-18 | 2003-06-25 | Organogenesis Inc. | Bioengineered flat sheet graft prosthesis and its use |
| JP4197157B2 (ja) * | 2001-07-16 | 2008-12-17 | デピュイ・プロダクツ・インコーポレイテッド | 軟骨修復再生装置および方法 |
| ATE390151T1 (de) * | 2001-10-26 | 2008-04-15 | Cook Biotech Inc | Medizinisches implantat mit netzartiger struktur |
| DE10249766A1 (de) | 2001-12-04 | 2003-07-10 | Matthias 99086 Erfurt Schreiber | Schichtgefässmatrix für den universellen Gewebeaufbau und Vorrichtung zur Inkubation |
| US20050283256A1 (en) * | 2004-02-09 | 2005-12-22 | Codman & Shurtleff, Inc. | Collagen device and method of preparing the same |
| AU2005215211B2 (en) | 2004-02-13 | 2011-11-03 | Smith & Nephew Orthopaedics Ag | Wound healing profile |
| FR2870450B1 (fr) * | 2004-05-18 | 2007-04-20 | David Jean Marie Nocca | Bandelette prothesique ajustable |
| EP1827527B1 (en) * | 2004-12-06 | 2016-08-24 | Cook Incorporated | Inflatable occlusion devices, methods, and systems |
| US20060246033A1 (en) * | 2005-03-02 | 2006-11-02 | Cook Biotech Incorporated | Injectable bulking agent compositions |
| WO2006101885A2 (en) * | 2005-03-16 | 2006-09-28 | Musculoskeletal Transplant Foundation | Soft tissue processing |
| US20100112543A1 (en) * | 2005-03-16 | 2010-05-06 | Manh-Dan Ngo | Processing soft tissue, methods and compositions related thereto |
| WO2006121887A2 (en) * | 2005-05-05 | 2006-11-16 | Cook Biotech Incorporated | Implantable materials and methods for inhibiting tissue adhesion formation |
| US8568761B2 (en) * | 2005-07-15 | 2013-10-29 | Cormatrix Cardiovascular, Inc. | Compositions for regenerating defective or absent myocardium |
| US20070014869A1 (en) * | 2005-07-15 | 2007-01-18 | Cormatrix Cardiovascular, Inc. | Compositions for reconstruction, replacement or repair of intracardiac tissue |
| US7429241B2 (en) * | 2005-09-29 | 2008-09-30 | Codman & Shurtleff, Inc. | Dural graft and method of preparing the same |
| AU2006304552B2 (en) * | 2005-10-18 | 2012-01-19 | Cook Biotech Incorporated | Medical device with affixation means |
| US20090209031A1 (en) * | 2006-01-26 | 2009-08-20 | Tyco Healthcare Group Lp | Medical device package |
| US9364215B2 (en) * | 2006-01-26 | 2016-06-14 | Covidien Lp | Medical device package |
| ES2375875T3 (es) * | 2006-07-31 | 2012-03-07 | Organogenesis, Inc. | Prótesis de mastopexia y de reconstrucción mamaria. |
| CA2604433A1 (en) * | 2006-10-06 | 2008-04-06 | Tyco Healthcare Group Lp | Medical device package including self-puncturable port |
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| US7614258B2 (en) * | 2006-10-19 | 2009-11-10 | C.R. Bard, Inc. | Prosthetic repair fabric |
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| EP2167149A2 (en) * | 2007-04-16 | 2010-03-31 | Tissue Science Laboratories PLC | Vascular implant |
| US20100191346A1 (en) * | 2007-04-16 | 2010-07-29 | Stephen Bloor | Bone implant |
| DE102007037051A1 (de) * | 2007-07-24 | 2009-01-29 | Aesculap Ag | Flächiges Implantat |
| EP3178442A1 (en) * | 2007-12-07 | 2017-06-14 | C.R. Bard Inc. | Implantable prosthesis |
| US8257434B2 (en) | 2007-12-18 | 2012-09-04 | Cormatrix Cardiovascular, Inc. | Prosthetic tissue valve |
| US8679176B2 (en) | 2007-12-18 | 2014-03-25 | Cormatrix Cardiovascular, Inc | Prosthetic tissue valve |
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| US9393002B2 (en) | 2008-02-18 | 2016-07-19 | Covidien Lp | Clip for implant deployment device |
| US9044235B2 (en) | 2008-02-18 | 2015-06-02 | Covidien Lp | Magnetic clip for implant deployment device |
| US8808314B2 (en) | 2008-02-18 | 2014-08-19 | Covidien Lp | Device and method for deploying and attaching an implant to a biological tissue |
| US8758373B2 (en) | 2008-02-18 | 2014-06-24 | Covidien Lp | Means and method for reversibly connecting a patch to a patch deployment device |
| US8317808B2 (en) | 2008-02-18 | 2012-11-27 | Covidien Lp | Device and method for rolling and inserting a prosthetic patch into a body cavity |
| US9398944B2 (en) | 2008-02-18 | 2016-07-26 | Covidien Lp | Lock bar spring and clip for implant deployment device |
| US9301826B2 (en) | 2008-02-18 | 2016-04-05 | Covidien Lp | Lock bar spring and clip for implant deployment device |
| US9393093B2 (en) | 2008-02-18 | 2016-07-19 | Covidien Lp | Clip for implant deployment device |
| US9833240B2 (en) | 2008-02-18 | 2017-12-05 | Covidien Lp | Lock bar spring and clip for implant deployment device |
| US9034002B2 (en) | 2008-02-18 | 2015-05-19 | Covidien Lp | Lock bar spring and clip for implant deployment device |
| AU2009201541B2 (en) * | 2008-04-23 | 2014-12-04 | Integra Lifesciences Corporation | Flowable collagen material for dural closure |
| EP2113262B1 (en) | 2008-04-29 | 2013-11-06 | Proxy Biomedical Limited | A Tissue Repair Implant |
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| US8469779B1 (en) | 2009-01-02 | 2013-06-25 | Lifecell Corporation | Method for debristling animal skin |
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| US8986377B2 (en) | 2009-07-21 | 2015-03-24 | Lifecell Corporation | Graft materials for surgical breast procedures |
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| CA2769666C (en) | 2009-08-17 | 2018-02-13 | Arie Levy | Means and method for reversibly connecting an implant to a deployment device |
| DE102010001271B8 (de) * | 2010-01-27 | 2012-12-06 | Urotiss Gmbh | Vernähbares Gewebetransplantatkonstrukt zur Rekonstruktion eines menschlichen oder tierischen Organs |
| KR20140024905A (ko) | 2011-05-27 | 2014-03-03 | 코매트릭스 카디오바스컬라 인코포레이티드 | 멸균된 무세포성 세포외 기질 조성물 및 이의 제조 방법 |
| US9005275B2 (en) | 2011-11-18 | 2015-04-14 | Mayo Foundation For Medical Education And Research | Methods for replacing a circumferential segment of an esophagus |
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| US9549812B2 (en) | 2012-01-13 | 2017-01-24 | Lifecell Corporation | Breast prostheses, methods of manufacturing breast prostheses, and methods of treatment using breast prostheses |
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| CN107928837B (zh) * | 2017-10-23 | 2023-06-13 | 上海利格泰生物科技股份有限公司 | 用于肩袖修复的部分可吸收补片及制造方法 |
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| US12697199B2 (en) | 2020-06-19 | 2026-08-04 | Davol Inc. | Prosthetic repair fabric |
| CN115970061A (zh) * | 2023-01-31 | 2023-04-18 | 上海卓阮医疗科技有限公司 | 用于缺乏血供场景的生物材料及其制备方法和应用 |
| CN116617471B (zh) * | 2023-07-24 | 2023-10-13 | 成都贝施美医疗科技股份有限公司 | 一种具有双层结构的口腔胶原膜及其制备方法 |
| CN119733107B (zh) * | 2024-12-10 | 2025-09-12 | 卓阮医疗科技(苏州)有限公司 | 一种抗感染生物补片在腹腔开放临时关腹材料中的应用 |
| CN119564938B (zh) * | 2024-12-10 | 2025-09-23 | 卓阮医疗科技(苏州)有限公司 | 一种实现可控缓释的高载药量的抗菌生物补片的工艺 |
| CN119564935A (zh) * | 2024-12-10 | 2025-03-07 | 卓阮医疗科技(苏州)有限公司 | 一种高封装药量抗菌缓释型生物补片 |
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-
1999
- 1999-06-04 EP EP99927195A patent/EP1082071B1/en not_active Expired - Lifetime
- 1999-06-04 MX MXPA00012062A patent/MXPA00012062A/es not_active IP Right Cessation
- 1999-06-04 JP JP2000552247A patent/JP4606583B2/ja not_active Expired - Fee Related
- 1999-06-04 CA CA2334364A patent/CA2334364C/en not_active Expired - Lifetime
- 1999-06-04 AU AU44163/99A patent/AU754838B2/en not_active Ceased
- 1999-06-04 DE DE69940504T patent/DE69940504D1/de not_active Expired - Lifetime
- 1999-06-04 ES ES99927195T patent/ES2323661T3/es not_active Expired - Lifetime
- 1999-06-04 AT AT99927195T patent/ATE424164T1/de not_active IP Right Cessation
- 1999-06-04 WO PCT/US1999/012400 patent/WO1999063051A2/en not_active Ceased
-
2003
- 2003-03-03 US US10/378,483 patent/US7121999B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU4416399A (en) | 1999-12-20 |
| EP1082071A2 (en) | 2001-03-14 |
| EP1082071A4 (en) | 2005-01-19 |
| WO1999063051A2 (en) | 1999-12-09 |
| EP1082071B1 (en) | 2009-03-04 |
| ES2323661T3 (es) | 2009-07-22 |
| JP4606583B2 (ja) | 2011-01-05 |
| CA2334364A1 (en) | 1999-12-09 |
| DE69940504D1 (enExample) | 2009-04-16 |
| WO1999063051A3 (en) | 2000-01-27 |
| JP2003527137A (ja) | 2003-09-16 |
| AU754838B2 (en) | 2002-11-28 |
| CA2334364C (en) | 2011-01-04 |
| US20030130747A1 (en) | 2003-07-10 |
| MXPA00012062A (es) | 2003-04-22 |
| US7121999B2 (en) | 2006-10-17 |
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