ATE40888T1 - Verfahren zur herstellung von ranitidin oder saeureadditionssalze davon und zwischenprodukte fuer diese herstellung. - Google Patents
Verfahren zur herstellung von ranitidin oder saeureadditionssalze davon und zwischenprodukte fuer diese herstellung.Info
- Publication number
- ATE40888T1 ATE40888T1 AT86306998T AT86306998T ATE40888T1 AT E40888 T1 ATE40888 T1 AT E40888T1 AT 86306998 T AT86306998 T AT 86306998T AT 86306998 T AT86306998 T AT 86306998T AT E40888 T1 ATE40888 T1 AT E40888T1
- Authority
- AT
- Austria
- Prior art keywords
- manufacture
- ranitidine
- intermediate products
- additional salts
- acid additional
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 2
- 239000002253 acid Substances 0.000 title 1
- 239000013067 intermediate product Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- VMXUWOKSQNHOCA-LCYFTJDESA-N ranitidine Chemical compound [O-][N+](=O)/C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 VMXUWOKSQNHOCA-LCYFTJDESA-N 0.000 title 1
- 229960000620 ranitidine Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/42—Singly bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK438485A DK153758C (da) | 1985-09-27 | 1985-09-27 | Fremgangsmåde til fremstilling af ranitidin eller syreadditionssalte deraf samt derivat af 5-((2-aminoethyl)thiomethyl)-2-furanmethanol til brug som udgangsmateriale for fremgangsmåden |
| EP86306998A EP0219225B1 (de) | 1985-09-27 | 1986-09-10 | Verfahren zur Herstellung von Ranitidin oder Säureadditionssalze davon und Zwischenprodukte für diese Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE40888T1 true ATE40888T1 (de) | 1989-03-15 |
Family
ID=8133057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86306998T ATE40888T1 (de) | 1985-09-27 | 1986-09-10 | Verfahren zur herstellung von ranitidin oder saeureadditionssalze davon und zwischenprodukte fuer diese herstellung. |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0219225B1 (de) |
| JP (2) | JPH0730063B2 (de) |
| KR (1) | KR940003296B1 (de) |
| AR (1) | AR241462A1 (de) |
| AT (1) | ATE40888T1 (de) |
| BR (1) | BR8604449A (de) |
| CA (1) | CA1263400A (de) |
| DE (1) | DE3662145D1 (de) |
| DK (2) | DK153758C (de) |
| ES (1) | ES2001804A6 (de) |
| FI (1) | FI89596C (de) |
| GR (1) | GR862445B (de) |
| IS (1) | IS3148A7 (de) |
| MA (1) | MA20777A1 (de) |
| NO (1) | NO169650C (de) |
| PT (1) | PT83420B (de) |
| SU (1) | SU1531854A3 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5541335A (en) * | 1994-07-11 | 1996-07-30 | Torcan Chemical Ltd. | Process for preparing nizatidine |
| US5981757A (en) * | 1998-02-02 | 1999-11-09 | Torcan Chemical Ltd. | Nizatidine preparation |
| CN112028862A (zh) * | 2020-08-18 | 2020-12-04 | 北京云鹏鹏程医药科技有限公司 | 一种低ndma含量盐酸雷尼替丁的制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR230442A1 (es) * | 1980-12-30 | 1984-04-30 | Glaxo Group Ltd | Procedimiento para la preparacion de n-(12-((5)(dimetilmino)metil(-2-furanilmetil)tto)etil)-ni-metil-1-nitroletenodiamina(ranitidina) |
-
1985
- 1985-09-27 DK DK438485A patent/DK153758C/da not_active IP Right Cessation
- 1985-09-27 DK DK438485D patent/DK153758B/da not_active IP Right Cessation
-
1986
- 1986-09-09 IS IS3148A patent/IS3148A7/is unknown
- 1986-09-10 EP EP86306998A patent/EP0219225B1/de not_active Expired
- 1986-09-10 DE DE8686306998T patent/DE3662145D1/de not_active Expired
- 1986-09-10 FI FI863651A patent/FI89596C/fi not_active IP Right Cessation
- 1986-09-10 AT AT86306998T patent/ATE40888T1/de not_active IP Right Cessation
- 1986-09-12 AR AR86305230A patent/AR241462A1/es active
- 1986-09-17 BR BR8604449A patent/BR8604449A/pt not_active Application Discontinuation
- 1986-09-18 NO NO86863735A patent/NO169650C/no unknown
- 1986-09-22 JP JP61224067A patent/JPH0730063B2/ja not_active Expired - Lifetime
- 1986-09-22 CA CA000518765A patent/CA1263400A/en not_active Expired
- 1986-09-23 PT PT83420A patent/PT83420B/pt not_active IP Right Cessation
- 1986-09-23 KR KR1019860007929A patent/KR940003296B1/ko not_active Expired - Fee Related
- 1986-09-25 GR GR862445A patent/GR862445B/el unknown
- 1986-09-26 SU SU864028187A patent/SU1531854A3/ru active
- 1986-09-26 ES ES8602232A patent/ES2001804A6/es not_active Expired
- 1986-09-26 MA MA21005A patent/MA20777A1/fr unknown
-
1994
- 1994-10-05 JP JP6240952A patent/JP2520376B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NO169650B (no) | 1992-04-13 |
| DK438485A (da) | 1987-03-28 |
| BR8604449A (pt) | 1987-05-12 |
| GR862445B (en) | 1987-01-27 |
| FI89596B (fi) | 1993-07-15 |
| KR940003296B1 (ko) | 1994-04-20 |
| JPS6272680A (ja) | 1987-04-03 |
| JP2520376B2 (ja) | 1996-07-31 |
| FI89596C (fi) | 1993-10-25 |
| PT83420B (pt) | 1989-01-17 |
| JPH0730063B2 (ja) | 1995-04-05 |
| DE3662145D1 (en) | 1989-03-30 |
| IS3148A7 (is) | 1987-03-28 |
| FI863651A0 (fi) | 1986-09-10 |
| JPH07316146A (ja) | 1995-12-05 |
| DK153758B (da) | 1988-08-29 |
| MA20777A1 (fr) | 1987-04-01 |
| EP0219225B1 (de) | 1989-02-22 |
| DK438485D0 (da) | 1985-09-27 |
| NO863735L (no) | 1987-03-30 |
| SU1531854A3 (ru) | 1989-12-23 |
| ES2001804A6 (es) | 1988-06-16 |
| EP0219225A1 (de) | 1987-04-22 |
| KR870003083A (ko) | 1987-04-15 |
| DK153758C (da) | 1995-10-02 |
| FI863651A7 (fi) | 1987-03-28 |
| PT83420A (en) | 1986-10-01 |
| NO863735D0 (no) | 1986-09-18 |
| AR241462A1 (es) | 1992-07-31 |
| CA1263400A (en) | 1989-11-28 |
| NO169650C (no) | 1992-07-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |