DE3679780D1 - Substituierte aminosulfonyl-6-nitrobenzosaeureester oder -amide, verfahren zur herstellung und diese enthaltende heilmittel. - Google Patents

Substituierte aminosulfonyl-6-nitrobenzosaeureester oder -amide, verfahren zur herstellung und diese enthaltende heilmittel.

Info

Publication number
DE3679780D1
DE3679780D1 DE8686114995T DE3679780T DE3679780D1 DE 3679780 D1 DE3679780 D1 DE 3679780D1 DE 8686114995 T DE8686114995 T DE 8686114995T DE 3679780 T DE3679780 T DE 3679780T DE 3679780 D1 DE3679780 D1 DE 3679780D1
Authority
DE
Germany
Prior art keywords
medicines
amides
production
acid esters
nitrobenzoic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686114995T
Other languages
English (en)
Inventor
Edward L Engelhardt
Walfred S Saari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE3679780D1 publication Critical patent/DE3679780D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/42—Oxygen atoms attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
DE8686114995T 1985-11-06 1986-10-29 Substituierte aminosulfonyl-6-nitrobenzosaeureester oder -amide, verfahren zur herstellung und diese enthaltende heilmittel. Expired - Fee Related DE3679780D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79556785A 1985-11-06 1985-11-06

Publications (1)

Publication Number Publication Date
DE3679780D1 true DE3679780D1 (de) 1991-07-18

Family

ID=25165850

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686114995T Expired - Fee Related DE3679780D1 (de) 1985-11-06 1986-10-29 Substituierte aminosulfonyl-6-nitrobenzosaeureester oder -amide, verfahren zur herstellung und diese enthaltende heilmittel.

Country Status (4)

Country Link
EP (1) EP0223124B1 (de)
JP (1) JPS62161757A (de)
CA (1) CA1276151C (de)
DE (1) DE3679780D1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0265806A1 (de) * 1986-10-21 1988-05-04 Merck & Co. Inc. 2-(Substituierte Sulfamyl)-6-nitrobenzoesäure, ihre Amide und Ester, verwendbar als Zusatzmittel in der Strahlentherapie
WO1994018165A1 (en) * 1993-02-12 1994-08-18 Pfizer Inc. Sulfonamide compounds as opioid k-receptor agonists
JP2000119271A (ja) 1998-08-12 2000-04-25 Hokuriku Seiyaku Co Ltd １ｈ―イミダゾピリジン誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1521932A (en) * 1976-03-08 1978-08-16 Labaz Sulphonamide derivatives and process for preparing the same
DE3048613A1 (de) * 1980-12-23 1982-07-29 Hoechst Ag, 6000 Frankfurt "formamidin-derivate, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen und deren herstellung"
EP0088849A1 (de) * 1982-03-11 1983-09-21 Choay S.A. Linksdrehende N-substituierte Benzensulfonamid-Verbindungen, Verfahren zu ihrer Herstellung und farmazeutische Zusammensetzungen die sie enthalten

Also Published As

Publication number Publication date
EP0223124A1 (de) 1987-05-27
EP0223124B1 (de) 1991-06-12
JPS62161757A (ja) 1987-07-17
CA1276151C (en) 1990-11-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee