ATE403085T1 - Mikrovorrichtung zum handhaben von flüssigkeiten und verfahren zur deren verwendung - Google Patents

Mikrovorrichtung zum handhaben von flüssigkeiten und verfahren zur deren verwendung

Info

Publication number
ATE403085T1
ATE403085T1 AT03787745T AT03787745T ATE403085T1 AT E403085 T1 ATE403085 T1 AT E403085T1 AT 03787745 T AT03787745 T AT 03787745T AT 03787745 T AT03787745 T AT 03787745T AT E403085 T1 ATE403085 T1 AT E403085T1
Authority
AT
Austria
Prior art keywords
devices
handling liquids
micro device
micro channel
relate
Prior art date
Application number
AT03787745T
Other languages
English (en)
Inventor
Tomas Ussing
Original Assignee
Memsflow Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Memsflow Aps filed Critical Memsflow Aps
Application granted granted Critical
Publication of ATE403085T1 publication Critical patent/ATE403085T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01B—BOILING; BOILING APPARATUS ; EVAPORATION; EVAPORATION APPARATUS
    • B01B1/00—Boiling; Boiling apparatus for physical or chemical purposes ; Evaporation in general
    • B01B1/005—Evaporation for physical or chemical purposes; Evaporation apparatus therefor, e.g. evaporation of liquids for gas phase reactions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/3033—Micromixers using heat to mix or move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30—Injector mixers
    • B01F25/31—Injector mixers in conduits or tubes through which the main component flows
    • B01F25/314—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/05—Mixers using radiation, e.g. magnetic fields or microwaves to mix the material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/05—Mixers using radiation, e.g. magnetic fields or microwaves to mix the material
    • B01F33/054—Mixers using radiation, e.g. magnetic fields or microwaves to mix the material the energy being in the form of a laser to modify the characteristics or conditions of the products, e.g. for heating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/301—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
    • B01F33/3017—Mixing chamber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/304—Micromixers the mixing being performed in a mixing chamber where the products are brought into contact
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B17/00—Pumps characterised by combination with, or adaptation to, specific driving engines or motors
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
    • F04B19/006—Micropumps
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
    • F04B19/20—Other positive-displacement pumps
    • F04B19/24—Pumping by heat expansion of pumped fluid
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0019—Valves using a microdroplet or microbubble as the valve member
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0034—Operating means specially adapted for microvalves
    • F16K99/0036—Operating means specially adapted for microvalves operated by temperature variations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00—Auxiliary or complementary information in relation with mixing
    • B01F2215/04—Technical information in relation with mixing
    • B01F2215/0413—Numerical information
    • B01F2215/0418—Geometrical information
    • B01F2215/0431—Numerical size values, e.g. diameter of a hole or conduit, area, volume, length, width, or ratios thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00—Auxiliary or complementary information in relation with mixing
    • B01F2215/04—Technical information in relation with mixing
    • B01F2215/0413—Numerical information
    • B01F2215/0436—Operational information
    • B01F2215/0477—Numerical time values
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00925—Irradiation
    • B01J2219/00934—Electromagnetic waves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/143—Quality control, feedback systems
    • B01L2200/147—Employing temperature sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/168—Specific optical properties, e.g. reflective coatings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1861—Means for temperature control using radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1861—Means for temperature control using radiation
    • B01L2300/1872—Infrared light
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0442—Moving fluids with specific forces or mechanical means specific forces thermal energy, e.g. vaporisation, bubble jet
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0082—Microvalves adapted for a particular use
    • F16K2099/0084—Chemistry or biology, e.g. "lab-on-a-chip" technology
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0082—Microvalves adapted for a particular use
    • F16K2099/0094—Micropumps

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Micromachines (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Electromagnetic Pumps, Or The Like (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
AT03787745T 2002-08-15 2003-08-14 Mikrovorrichtung zum handhaben von flüssigkeiten und verfahren zur deren verwendung ATE403085T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200201209 2002-08-15
DKPA200300642 2003-04-29

Publications (1)

Publication Number Publication Date
ATE403085T1 true ATE403085T1 (de) 2008-08-15

Family

ID=31889350

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03787745T ATE403085T1 (de) 2002-08-15 2003-08-14 Mikrovorrichtung zum handhaben von flüssigkeiten und verfahren zur deren verwendung

Country Status (7)

Country Link
US (1) US20060051214A1 (de)
EP (1) EP1534954B1 (de)
JP (1) JP2005538287A (de)
AT (1) ATE403085T1 (de)
AU (1) AU2003254637A1 (de)
DE (1) DE60322548D1 (de)
WO (1) WO2004016948A1 (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7530795B2 (en) 2003-06-13 2009-05-12 Canon Kabushiki Kaisha Fluid control mechanism
JP3927968B2 (ja) * 2003-06-13 2007-06-13 キヤノン株式会社 流体制御機構
US7444817B2 (en) 2003-06-13 2008-11-04 Canon Kabushiki Kaisha Optical micromotor, micropump using same and microvalve using same
FR2873171B1 (fr) 2004-07-19 2007-12-07 Centre Nat Rech Scient Cnrse Circuit microfluidique a composant actif
US20060028908A1 (en) * 2004-08-03 2006-02-09 Suriadi Arief B Micro-mixer
JP4442884B2 (ja) * 2004-09-24 2010-03-31 アイダエンジニアリング株式会社 マイクロ流体デバイス
JP4742184B2 (ja) * 2004-09-30 2011-08-10 アークレイ株式会社 分析装置
EP1812773A1 (de) * 2004-10-26 2007-08-01 Memsflow ApS Verfahren und system zur positionsbestimmung
SE0402609L (sv) * 2004-10-26 2006-03-21 Acreo Ab Mikrofluidikanordning
EP1836698B1 (de) * 2004-12-31 2016-03-02 FluimediX ApS Generation von pulsierenden druckwellen, z.b. für zellyse
FR2901717A1 (fr) * 2006-05-30 2007-12-07 Centre Nat Rech Scient Procede de traitement de gouttes dans un circuit microfluidique.
US20080032311A1 (en) * 2006-08-04 2008-02-07 Zhenghua Ji Low volume mixing of sample
JP4858909B2 (ja) * 2006-10-23 2012-01-18 独立行政法人産業技術総合研究所 吐出機構付マイクロ流体デバイス及び微量サンプル吐出方法
JP2008116381A (ja) * 2006-11-07 2008-05-22 Tokyo Univ Of Agriculture & Technology マイクロポンプ
EP2185285A4 (de) * 2007-08-14 2015-08-19 Arcxis Biotechnologies Inc Herstellung von polymermikrofluidischenbiochips
JP4539707B2 (ja) 2007-10-25 2010-09-08 ソニー株式会社 微小粒子分取装置及び微小粒子分取用基板、並びに微小粒子分取方法
WO2009122399A1 (en) * 2008-03-31 2009-10-08 Technion Research & Development Foundation Ltd. Method and system for manipulating fluid medium
JP4856733B2 (ja) * 2008-04-28 2012-01-18 積水化学工業株式会社 マイクロポンプ装置
US10066977B2 (en) 2009-01-26 2018-09-04 Canon U.S. Life Sciences, Inc. Microfluidic flow monitoring
US9404152B2 (en) 2009-01-26 2016-08-02 Canon U.S. Life Sciences, Inc. Microfluidic flow monitoring
FR2950544B1 (fr) * 2009-09-29 2011-12-09 Ecole Polytech Circuit microfluidique
FR2967148B1 (fr) * 2010-11-10 2012-12-21 Commissariat Energie Atomique Procede d'evaporation controlee d'une goutte liquide dans un dispositif microfluidique.
EP2620681A1 (de) * 2012-01-26 2013-07-31 Alcatel Lucent Fluidventileinheit
US8891949B2 (en) * 2012-02-03 2014-11-18 Lexmark International, Inc. Micro-fluidic pump
WO2014110149A2 (en) * 2013-01-08 2014-07-17 Stoneburner Jon F Method of testing or treating the presence of live viruses
JP2015188806A (ja) * 2014-03-27 2015-11-02 キヤノン株式会社 液体搬送装置
WO2016153897A1 (en) * 2015-03-20 2016-09-29 Baker Hughes Incorporated Systems and methods for controlling downhole linear motors
CN104984773B (zh) * 2015-05-25 2016-10-05 重庆大学 一种微通道内强化流体混合的方法
US10378526B2 (en) * 2015-12-21 2019-08-13 Funai Electric Co., Ltd Method and apparatus for metering and vaporizing fluids
US10208739B2 (en) * 2016-01-05 2019-02-19 Funai Electric Co., Ltd. Microfluidic pump with thermal control
US10704540B2 (en) * 2016-04-27 2020-07-07 Anthony Calomeris Ultrashort pulse laser-driven shock wave gas compressor
US10317962B2 (en) 2016-08-16 2019-06-11 International Business Machines Corporation Inducing heterogeneous microprocessor behavior using non-uniform cooling
US10558249B2 (en) 2016-09-27 2020-02-11 International Business Machines Corporation Sensor-based non-uniform cooling
JP7271108B2 (ja) * 2017-08-31 2023-05-11 キヤノン株式会社 ウルトラファインバブル含有液の製造装置及びウルトラファインバブル含有液の製造方法
WO2019044913A1 (en) * 2017-08-31 2019-03-07 Canon Kabushiki Kaisha METHOD FOR GENERATING ULTRAFINE BUBBLES, MANUFACTURING APPARATUS AND METHOD FOR MANUFACTURING LIQUID CONTAINING ULTRAFINE BUBBLES, AND LIQUID CONTAINING ULTRA FINE BUBBLES
JP6950954B2 (ja) * 2017-12-22 2021-10-13 国立大学法人金沢大学 液体充填方法、ｓｉｃｍ用プローブの製造方法、ｓｉｃｍ用プローブ及びｓｉｃｍ
US12458970B2 (en) 2018-11-19 2025-11-04 Korea Research Institute Of Bioscience And Biotechnology Light-digital PCR chamber and light-digital PCR device using same
JP7282548B2 (ja) * 2019-02-28 2023-05-29 キヤノン株式会社 ウルトラファインバブル生成方法、およびウルトラファインバブル生成装置
JP7277177B2 (ja) * 2019-02-28 2023-05-18 キヤノン株式会社 ウルトラファインバブル生成装置及びウルトラファインバブル生成方法
JP7278799B2 (ja) * 2019-02-28 2023-05-22 キヤノン株式会社 微細バブル生成装置、及び微細バブル生成方法
JP7277178B2 (ja) * 2019-02-28 2023-05-18 キヤノン株式会社 ウルトラファインバブル生成装置
CN109958487B (zh) * 2019-03-13 2024-05-28 华北电力大学 一种基于光热效应的蒸汽驱动液柱活塞式运动执行器
EP3946714A1 (de) * 2019-03-29 2022-02-09 Palogen, Inc. Nanoporenvorrichtung und biosyntheseverfahren damit
WO2020210981A1 (en) * 2019-04-16 2020-10-22 Boe Technology Group Co., Ltd. Micro-channel device and manufacturing method thereof and micro-fluidic system
CN114728281B (zh) * 2019-10-18 2023-11-03 瞬知（广州）健康科技有限公司 用于输注流体的系统和方法
CN111204417B (zh) * 2020-02-27 2024-07-16 北京大学 一种微型光控漂浮载具及其光控制方法
US20220008913A1 (en) * 2020-06-27 2022-01-13 Jeffrey G. Manni Optically actuated fluid control for microfluidic structures
CN116568799A (zh) * 2020-09-24 2023-08-08 株式会社尼康 生物体的操作方法及生物体操作装置
JP7786383B2 (ja) * 2020-09-24 2025-12-16 株式会社ニコン 生物体操作方法および生物体操作装置
US20220298529A1 (en) * 2021-03-18 2022-09-22 Canon Kabushiki Kaisha Compound introduction apparatus and compound introduction method

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4159427A (en) * 1975-12-23 1979-06-26 Messerschmitt-Boelkow-Blohm Gesellschaft Mit Beschraenkter Haftung Apparatus for utilizing natural energies
CA1127227A (en) * 1977-10-03 1982-07-06 Ichiro Endo Liquid jet recording process and apparatus therefor
US4463359A (en) * 1979-04-02 1984-07-31 Canon Kabushiki Kaisha Droplet generating method and apparatus thereof
DE3224061A1 (de) * 1981-06-29 1983-01-05 Canon K.K., Tokyo Fluessigkeitsstrahl-aufzeichnungsverfahren
US4795243A (en) * 1983-06-10 1989-01-03 Canon Kabushiki Kaisha Granular member moving method and apparatus
US5053787A (en) * 1988-01-27 1991-10-01 Canon Kabushiki Kaisha Ink jet recording method and head having additional generating means in the liquid chamber
US5186001A (en) * 1991-11-08 1993-02-16 University Of Southern California Transient energy release microdevices and methods
JPH05240155A (ja) * 1992-02-28 1993-09-17 Seiko Instr Inc 流体装置
DE4220077A1 (de) * 1992-06-19 1993-12-23 Bosch Gmbh Robert Mikropumpe
US5649423A (en) * 1994-06-07 1997-07-22 Sandia Corporation Micromechanism linear actuator with capillary force sealing
US5602386A (en) * 1994-09-07 1997-02-11 Ceramoptec Industrues, Inc. Optically powered remote micro devices employing fiber optics
TW365578B (en) * 1995-04-14 1999-08-01 Canon Kk Liquid ejecting head, liquid ejecting device and liquid ejecting method
EP1009520A4 (de) * 1997-01-24 2003-05-14 Univ California Gerät und verfahren zum planaren laminaren mischen
US6062681A (en) * 1998-07-14 2000-05-16 Hewlett-Packard Company Bubble valve and bubble valve-based pressure regulator
US6186659B1 (en) * 1998-08-21 2001-02-13 Agilent Technologies Inc. Apparatus and method for mixing a film of fluid
US6283718B1 (en) * 1999-01-28 2001-09-04 John Hopkins University Bubble based micropump
US20010010799A1 (en) * 1999-07-07 2001-08-02 Andrea Prosperetti Bubble-based micropump
US20030021694A1 (en) * 2001-07-25 2003-01-30 Yevin Oleg A. Nano and micro metric dimensional systems and methods for nanopump based technology
US6655924B2 (en) * 2001-11-07 2003-12-02 Intel Corporation Peristaltic bubble pump
KR20050059752A (ko) * 2003-12-15 2005-06-21 삼성전자주식회사 개스 버블을 이용하여 유체를 펌핑하는 장치 및 방법

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AU2003254637A1 (en) 2004-03-03
WO2004016948A1 (en) 2004-02-26
DE60322548D1 (de) 2008-09-11

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