ATE400602T1 - Verfahren zur herstellung von hydrogelen aus thiosulfonat-zusammensetzungen und ihre verwendungen - Google Patents
Verfahren zur herstellung von hydrogelen aus thiosulfonat-zusammensetzungen und ihre verwendungenInfo
- Publication number
- ATE400602T1 ATE400602T1 AT03800398T AT03800398T ATE400602T1 AT E400602 T1 ATE400602 T1 AT E400602T1 AT 03800398 T AT03800398 T AT 03800398T AT 03800398 T AT03800398 T AT 03800398T AT E400602 T1 ATE400602 T1 AT E400602T1
- Authority
- AT
- Austria
- Prior art keywords
- thiosulfonate
- compositions
- hydrogels
- forming
- hydrogel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/334—Polymers modified by chemical after-treatment with organic compounds containing sulfur
- C08G65/3342—Polymers modified by chemical after-treatment with organic compounds containing sulfur having sulfur bound to carbon and hydrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
- A61L24/0031—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/046—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2300/00—Characterised by the use of unspecified polymers
- C08J2300/14—Water soluble or water swellable polymers, e.g. aqueous gels
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2381/00—Characterised by the use of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing sulfur with or without nitrogen, oxygen, or carbon only; Polysulfones; Derivatives of such polymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2203/00—Applications
- C08L2203/02—Applications for biomedical use
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Dispersion Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Materials Engineering (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Polyethers (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Colloid Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43725202P | 2002-12-31 | 2002-12-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE400602T1 true ATE400602T1 (de) | 2008-07-15 |
Family
ID=32713157
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03800398T ATE400602T1 (de) | 2002-12-31 | 2003-12-31 | Verfahren zur herstellung von hydrogelen aus thiosulfonat-zusammensetzungen und ihre verwendungen |
Country Status (6)
Country | Link |
---|---|
US (5) | US7312301B2 (de) |
EP (1) | EP1578843B1 (de) |
AT (1) | ATE400602T1 (de) |
AU (1) | AU2003300140A1 (de) |
DE (1) | DE60322111D1 (de) |
WO (1) | WO2004060967A1 (de) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE400602T1 (de) | 2002-12-31 | 2008-07-15 | Nektar Therapeutics Al Corp | Verfahren zur herstellung von hydrogelen aus thiosulfonat-zusammensetzungen und ihre verwendungen |
EP1596887B1 (de) | 2003-02-26 | 2022-03-23 | Nektar Therapeutics | Polymer-factor viii-konjugate |
EP1617872A4 (de) * | 2003-04-10 | 2011-09-07 | 3M Innovative Properties Co | Verfahren und zusammensetzungen zur verbesserung der immunantwort |
CA2521682A1 (en) * | 2003-04-10 | 2004-12-16 | 3M Innovative Properties Company | Delivery of immune response modifier compounds using metal-containing particulate support materials |
JP4805911B2 (ja) * | 2004-03-15 | 2011-11-02 | ネクター セラピューティクス | Hiv侵入阻害剤のポリマー系組成物及び複合体 |
US8303973B2 (en) * | 2004-09-17 | 2012-11-06 | Angiotech Pharmaceuticals (Us), Inc. | Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use |
US20070060658A1 (en) * | 2005-08-31 | 2007-03-15 | Diaz David D | Stabilization of organogels and hydrogels by azide-alkyne [3+2] cycloaddition |
EP1968644B1 (de) | 2005-12-16 | 2012-06-27 | Nektar Therapeutics | Polymerkonjugate von glp-1 |
US7462627B2 (en) | 2006-02-09 | 2008-12-09 | Enzon Pharmaceuticals, Inc. | Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers |
US7671067B2 (en) | 2006-02-09 | 2010-03-02 | Enzon Pharmaceuticals, Inc. | Treatment of non-hodgkin's lymphomas with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamtothecin |
CN101500623B (zh) | 2006-06-15 | 2016-08-24 | 微温森公司 | 一种由可膨胀聚合物构成的栓塞器械 |
EP1891941A1 (de) * | 2006-08-11 | 2008-02-27 | OctoPlus Technologies B.V. | Wässrige Gele enthaltend Mikrokügelchen |
BRPI0807232A2 (pt) | 2007-02-09 | 2014-04-29 | Enzon Pharmaceuticals Inc | Tratamento de cânceres resistentes ou refratários com conjugados poliméricos multi-braços de 7-etil-10-hidroxicamptotecina |
US20080287633A1 (en) * | 2007-05-18 | 2008-11-20 | Drumheller Paul D | Hydrogel Materials |
US8067028B2 (en) * | 2007-08-13 | 2011-11-29 | Confluent Surgical Inc. | Drug delivery device |
CA2709379C (en) | 2007-12-21 | 2016-08-16 | Microvention, Inc. | Hydrogel filaments for biomedical uses |
US20100112014A1 (en) * | 2008-04-11 | 2010-05-06 | Gilbert Ryan J | Novel hydrogel compositions and methods of using |
US10799593B2 (en) | 2008-06-09 | 2020-10-13 | Northwestern University | Nanodiamond particle complexes |
US20100040672A1 (en) * | 2008-06-09 | 2010-02-18 | Northwestern University | Delivery of therapeutics |
MX2011001583A (es) | 2008-08-11 | 2011-04-04 | Nektar Therapeutics | Conjugados de alcanoato polimericos de multiples brazos. |
US8443146B2 (en) * | 2008-09-18 | 2013-05-14 | International Business Machines Corporation | Techniques for cache injection in a processor system responsive to a specific instruction sequence |
US8429349B2 (en) * | 2008-09-18 | 2013-04-23 | International Business Machines Corporation | Techniques for cache injection in a processor system with replacement policy position modification |
CA2777171C (en) | 2009-10-26 | 2017-09-19 | Microvention, Inc. | Embolization device constructed from expansile polymer |
WO2011065916A1 (en) * | 2009-11-24 | 2011-06-03 | Agency For Science, Technology And Research | Crosslinking branched molecule through thiol-disulfide exchange to form hydrogel |
US8524215B2 (en) * | 2010-08-02 | 2013-09-03 | Janssen Biotech, Inc. | Absorbable PEG-based hydrogels |
WO2012088422A1 (en) | 2010-12-22 | 2012-06-28 | Nektar Therapeutics | Multi-arm polymeric prodrug conjugates of taxane-based compounds |
WO2012088445A1 (en) | 2010-12-22 | 2012-06-28 | Nektar Therapeutics | Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds |
WO2012145431A2 (en) | 2011-04-18 | 2012-10-26 | Microvention, Inc. | Embolic devices |
SG11201400444VA (en) * | 2011-09-07 | 2014-04-28 | Prolynx Llc | Hydrogels with biodegradable crosslinking |
US9011884B2 (en) | 2012-04-18 | 2015-04-21 | Microvention, Inc. | Embolic devices |
CN104363922B (zh) | 2012-06-14 | 2017-06-30 | 微仙美国有限公司 | 聚合物治疗组合物 |
CA2870170C (en) | 2012-09-12 | 2018-06-12 | Boston Scientific Scimed, Inc. | Adhesive stent coating for anti-migration |
WO2014059446A1 (en) * | 2012-10-12 | 2014-04-17 | Case Western Reserve University | Biodegradable hydrogel for polynucleotide delivery |
BR112015008245B1 (pt) | 2012-10-15 | 2022-09-27 | Microvention, Inc | Composições poliméricas de tratamento |
EP3030278B1 (de) | 2013-08-08 | 2018-09-19 | Boston Scientific Scimed, Inc. | Stent mit löslichem oder abbaubarem klebstoffpolymer zur verhinderung einer migration |
US10173375B2 (en) | 2014-03-05 | 2019-01-08 | Bacterin International, Inc. | Shaped fiber-based products and method of manufacture thereof |
WO2015153996A1 (en) | 2014-04-03 | 2015-10-08 | Micro Vention, Inc. | Embolic devices |
US10092663B2 (en) | 2014-04-29 | 2018-10-09 | Terumo Corporation | Polymers |
US10226533B2 (en) | 2014-04-29 | 2019-03-12 | Microvention, Inc. | Polymer filaments including pharmaceutical agents and delivering same |
US11046828B2 (en) * | 2015-04-21 | 2021-06-29 | Trustees Of Tufts College | Fabrication of macroporous monodisperse hydrogel microspheres |
WO2016201250A1 (en) | 2015-06-11 | 2016-12-15 | Microvention, Inc. | Expansile device for implantation |
US10821004B2 (en) * | 2015-06-30 | 2020-11-03 | Bacterin Interational, Inc. | Expandable bone grafts and methods of manufacture thereof |
US10368874B2 (en) | 2016-08-26 | 2019-08-06 | Microvention, Inc. | Embolic compositions |
CN107602432B (zh) * | 2017-10-01 | 2019-06-07 | 刘云晖 | 一种可溶性水凝胶用交联剂及其制备方法和应用 |
US10576182B2 (en) | 2017-10-09 | 2020-03-03 | Microvention, Inc. | Radioactive liquid embolic |
CN111388748B (zh) * | 2020-03-03 | 2021-08-06 | 东华大学 | 一种抗菌止血多功能复合水凝胶敷料及其制备方法 |
Family Cites Families (22)
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BE598976A (de) * | 1960-01-11 | |||
DE1223156B (de) * | 1961-05-27 | 1966-08-18 | Hoechst Ag | Verfahren zur Herstellung von hoehermolekularen Polykondensaten |
CS159361B1 (de) * | 1970-09-08 | 1975-01-31 | ||
IE49097B1 (en) * | 1978-11-10 | 1985-07-24 | Ic Gas Int Ltd | Thermal energy storage material |
AU537741B2 (en) * | 1979-03-21 | 1984-07-12 | British Technology Group Limited | Controlled release compositions |
JPS60114584A (ja) * | 1983-11-25 | 1985-06-21 | Otsuka Chem Co Ltd | チオスルホナ−ト誘導体の製造法 |
JP2664153B2 (ja) * | 1987-06-05 | 1997-10-15 | 富士写真フイルム株式会社 | ハロゲン化銀カラー写真感光材料およびその現像処理方法 |
US4983579A (en) * | 1988-11-18 | 1991-01-08 | International Flavors & Fragrances Inc. | Cyano-substituted sulfur containing compounds, compositions containing same, processes for preparing same and organoleptic uses thereof |
DE4014537A1 (de) * | 1990-05-07 | 1991-11-14 | Goldschmidt Ag Th | Verfahren zur herstellung von hochelastischen, polyurethangruppen aufweisenden schaumstoffen mit verminderter stauchhaerte |
US5393798A (en) * | 1992-06-05 | 1995-02-28 | Spenco Medical Corporation | Hydrogel material and method of preparation |
DE69315213T2 (de) | 1992-07-06 | 1998-03-19 | Biomira Inc | Photoaktivierung von proteinen zu konjugationszwecken |
US5672662A (en) * | 1995-07-07 | 1997-09-30 | Shearwater Polymers, Inc. | Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications |
PT1061954E (pt) | 1998-03-12 | 2004-10-29 | Nektar Therapeutics Al Corp | Derivados de poli(etileno glicol) com grupos reactivos proximos |
DE69939538D1 (de) * | 1998-07-02 | 2008-10-23 | Univ Toronto | Mit einer kohlenhydratgruppe chemisch modifizierte proteine |
US6131274A (en) * | 1999-07-01 | 2000-10-17 | 3Com Corporation | Apparatus and method for guiding a circuit board into an electronic chassis |
JP4344110B2 (ja) | 1999-10-08 | 2009-10-14 | ネクター セラピューティックス エイエル,コーポレイション | ヘテロ二官能性ポリエチレングリコール誘導体およびその調製方法 |
GB2374072B (en) * | 2000-06-16 | 2004-09-22 | Nippon Catalytic Chem Ind | Crosslinked polymer method for manufacturing it and use thereof |
JP2002049123A (ja) * | 2000-08-04 | 2002-02-15 | Fuji Photo Film Co Ltd | 熱現像感光材料および画像形成方法 |
AU2001293581A1 (en) * | 2000-09-26 | 2002-04-08 | Neurortho Implants Design, Llc | Inter-vertebral disc prosthesis for lumbar rachis through posterior surgery thereof |
US7053150B2 (en) * | 2000-12-18 | 2006-05-30 | Nektar Therapeutics Al, Corporation | Segmented polymers and their conjugates |
TW593427B (en) * | 2000-12-18 | 2004-06-21 | Nektar Therapeutics Al Corp | Synthesis of high molecular weight non-peptidic polymer derivatives |
ATE400602T1 (de) | 2002-12-31 | 2008-07-15 | Nektar Therapeutics Al Corp | Verfahren zur herstellung von hydrogelen aus thiosulfonat-zusammensetzungen und ihre verwendungen |
-
2003
- 2003-12-31 AT AT03800398T patent/ATE400602T1/de not_active IP Right Cessation
- 2003-12-31 DE DE60322111T patent/DE60322111D1/de not_active Expired - Lifetime
- 2003-12-31 WO PCT/US2003/041706 patent/WO2004060967A1/en not_active Application Discontinuation
- 2003-12-31 EP EP03800398A patent/EP1578843B1/de not_active Expired - Lifetime
- 2003-12-31 AU AU2003300140A patent/AU2003300140A1/en not_active Abandoned
- 2003-12-31 US US10/751,010 patent/US7312301B2/en active Active
-
2007
- 2007-09-27 US US11/904,985 patent/US7598338B2/en not_active Expired - Lifetime
-
2009
- 2009-08-25 US US12/547,369 patent/US8097695B2/en not_active Expired - Fee Related
-
2011
- 2011-12-14 US US13/325,936 patent/US8247598B2/en not_active Expired - Lifetime
-
2012
- 2012-07-20 US US13/554,292 patent/US8450390B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US20120289609A1 (en) | 2012-11-15 |
DE60322111D1 (de) | 2008-08-21 |
US8097695B2 (en) | 2012-01-17 |
US20050143484A1 (en) | 2005-06-30 |
EP1578843A1 (de) | 2005-09-28 |
US20100004424A1 (en) | 2010-01-07 |
AU2003300140A1 (en) | 2004-07-29 |
US7312301B2 (en) | 2007-12-25 |
US20080033105A1 (en) | 2008-02-07 |
US8450390B2 (en) | 2013-05-28 |
WO2004060967A1 (en) | 2004-07-22 |
EP1578843B1 (de) | 2008-07-09 |
US7598338B2 (en) | 2009-10-06 |
US20120088927A1 (en) | 2012-04-12 |
US8247598B2 (en) | 2012-08-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |