ATE398178T1 - Ein rekombinanter expressionvektor für menschliches parathyroidhormon - Google Patents

Ein rekombinanter expressionvektor für menschliches parathyroidhormon

Info

Publication number
ATE398178T1
ATE398178T1 AT98925953T AT98925953T ATE398178T1 AT E398178 T1 ATE398178 T1 AT E398178T1 AT 98925953 T AT98925953 T AT 98925953T AT 98925953 T AT98925953 T AT 98925953T AT E398178 T1 ATE398178 T1 AT E398178T1
Authority
AT
Austria
Prior art keywords
expression vector
parathyroid hormone
recombinant
gene
recombinant expression
Prior art date
Application number
AT98925953T
Other languages
English (en)
Inventor
Eun-Kyung Jung
Doo-Hong Park
Soo-Il Chung
Original Assignee
Mogam Biotech Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mogam Biotech Res Inst filed Critical Mogam Biotech Res Inst
Application granted granted Critical
Publication of ATE398178T1 publication Critical patent/ATE398178T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/635Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01019Phosphoribulokinase (2.7.1.19)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98925953T 1997-07-25 1998-06-05 Ein rekombinanter expressionvektor für menschliches parathyroidhormon ATE398178T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019970035230A KR100230578B1 (ko) 1997-07-25 1997-07-25 포스포리불로키나제를 융합파트너로 이용하는 재조합 인간 부갑상선호르몬의 발현벡터

Publications (1)

Publication Number Publication Date
ATE398178T1 true ATE398178T1 (de) 2008-07-15

Family

ID=19515755

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98925953T ATE398178T1 (de) 1997-07-25 1998-06-05 Ein rekombinanter expressionvektor für menschliches parathyroidhormon

Country Status (11)

Country Link
US (1) US6500647B1 (de)
EP (1) EP1012289B1 (de)
JP (1) JP3480836B2 (de)
KR (1) KR100230578B1 (de)
CN (1) CN1154727C (de)
AT (1) ATE398178T1 (de)
AU (1) AU728703B2 (de)
CA (1) CA2298106C (de)
DE (1) DE69839607D1 (de)
ES (1) ES2306476T3 (de)
WO (1) WO1999005277A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1301740A (zh) * 1999-12-24 2001-07-04 上海博德基因开发有限公司 一种新的多肽——甲状旁腺激素9和编码这种多肽的多核苷酸
CN1188522C (zh) * 2001-07-20 2005-02-09 健力福生化技术(上海)有限公司 一种血栓靶向性溶栓蛋白表达质粒及其构建
FI116068B (fi) * 2003-09-15 2005-09-15 Fit Biotech Oyj Plc Uusi selektiojärjestelmä, siinä käyttökelpoinen vektori, bakteerisolukantoja sekä menetelmä solujen valikoimiseksi
AU2006315132A1 (en) * 2005-11-10 2007-05-24 Board Of Control Of Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
RU2441019C2 (ru) 2007-08-09 2012-01-27 Юсв Лимитед Способ синтеза рекомбинантного паратиреоидного гормона человека
EP2201120B1 (de) 2007-09-21 2013-12-25 Cadila Healthcare Limited Zur hohen expression von peptiden geeignete gcsf-fusionsproteinsysteme
KR101387693B1 (ko) 2008-12-04 2014-04-21 한국생명공학연구원 고분비성 단백질의 스크리닝 및 재조합 단백질의 생산을 위한 융합 파트너로서 그의 용도
CN106995495A (zh) 2009-01-12 2017-08-01 希托马克斯医疗有限责任公司 修饰抗体组合物及其制备和使用方法
EP2509996A1 (de) 2009-12-07 2012-10-17 Michigan Technological University Schwarzbär-parathyroid-hormon und verfahren zur verwendung des schwarzbär-parathyroid-hormons
US11135269B2 (en) 2013-12-11 2021-10-05 The General Hospital Corporation Use of mullerian inhibiting substance (MIS) proteins for contraception and ovarian reserve preservation
CN111172130B (zh) * 2020-01-09 2021-08-20 中国科学院生物物理研究所 一组拟南芥磷酸核酮糖激酶的突变体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3312928A1 (de) * 1983-04-11 1984-11-22 Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig Human-parathormon produzierende hybridvektoren und human-parathormongen
US5171670A (en) * 1989-05-12 1992-12-15 The General Hospital Corporation Recombinant dna method for production of parathyroid hormone
DE69111371T2 (de) * 1990-09-28 1996-03-14 Takeda Chemical Industries Ltd Synthetisches Gen für menschliches Parathyroidhormon.
EP0499990B1 (de) * 1991-02-19 1996-05-15 Takeda Chemical Industries, Ltd. Verfahren zur Herstellung von cysteinfreien Peptiden

Also Published As

Publication number Publication date
ES2306476T3 (es) 2008-11-01
AU728703B2 (en) 2001-01-18
CN1275163A (zh) 2000-11-29
JP2001511346A (ja) 2001-08-14
KR100230578B1 (ko) 1999-12-01
WO1999005277A1 (en) 1999-02-04
EP1012289B1 (de) 2008-06-11
CA2298106C (en) 2006-03-14
DE69839607D1 (de) 2008-07-24
CA2298106A1 (en) 1999-02-04
CN1154727C (zh) 2004-06-23
EP1012289A1 (de) 2000-06-28
KR19990011970A (ko) 1999-02-18
JP3480836B2 (ja) 2003-12-22
US6500647B1 (en) 2002-12-31
AU7789498A (en) 1999-02-16

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