ATE394475T1 - Methode zur herstellung von infektiösem reovirus - Google Patents

Methode zur herstellung von infektiösem reovirus

Info

Publication number
ATE394475T1
ATE394475T1 AT05009952T AT05009952T ATE394475T1 AT E394475 T1 ATE394475 T1 AT E394475T1 AT 05009952 T AT05009952 T AT 05009952T AT 05009952 T AT05009952 T AT 05009952T AT E394475 T1 ATE394475 T1 AT E394475T1
Authority
AT
Austria
Prior art keywords
producing infectious
infectious reovirus
reovirus
producing
infectious
Prior art date
Application number
AT05009952T
Other languages
English (en)
Inventor
Matthew C Coffey
Bradley G Thompson
Original Assignee
Oncolytics Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncolytics Biotech Inc filed Critical Oncolytics Biotech Inc
Application granted granted Critical
Publication of ATE394475T1 publication Critical patent/ATE394475T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • A61K35/765Reovirus; Rotavirus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12051Methods of production or purification of viral material
AT05009952T 2000-08-10 2001-07-20 Methode zur herstellung von infektiösem reovirus ATE394475T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22402600P 2000-08-10 2000-08-10

Publications (1)

Publication Number Publication Date
ATE394475T1 true ATE394475T1 (de) 2008-05-15

Family

ID=22838987

Family Applications (2)

Application Number Title Priority Date Filing Date
AT01953084T ATE298788T1 (de) 2000-08-10 2001-07-20 Verfahren zur herstellung von infektiösen reoviren
AT05009952T ATE394475T1 (de) 2000-08-10 2001-07-20 Methode zur herstellung von infektiösem reovirus

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT01953084T ATE298788T1 (de) 2000-08-10 2001-07-20 Verfahren zur herstellung von infektiösen reoviren

Country Status (19)

Country Link
US (4) US6528305B2 (de)
EP (2) EP1586634B1 (de)
JP (2) JP4009532B2 (de)
AR (1) AR033993A1 (de)
AT (2) ATE298788T1 (de)
AU (2) AU7562801A (de)
BR (1) BR0113122A (de)
CA (1) CA2415749C (de)
DE (2) DE60133947D1 (de)
DK (2) DK1309672T3 (de)
ES (2) ES2305940T3 (de)
HK (1) HK1082765A1 (de)
IL (2) IL153847A0 (de)
MX (1) MXPA03000846A (de)
NZ (1) NZ523510A (de)
PT (2) PT1586634E (de)
TW (1) TWI289158B (de)
WO (1) WO2002012435A1 (de)
ZA (1) ZA200300410B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6545492B1 (en) * 1999-09-20 2003-04-08 Europaisches Laboratorium Fur Molekularbiologie (Embl) Multiple local probe measuring device and method
TWI289158B (en) * 2000-08-10 2007-11-01 Oncolytics Biotech Inc Method of producing infectious reovirus
EP2253701B1 (de) 2001-03-16 2014-08-13 Oncolytics Biotech Inc. Methode zur Extraktion von Virus aus einer Zellkultur
US20040115170A1 (en) * 2001-11-30 2004-06-17 Brown Earl Garnet Oncolytic virus
CA2374388C (en) * 2002-02-28 2005-07-12 Matthew C. Coffey The use of ribozymes in the detection of adventitious agents
US20040005546A1 (en) 2002-02-28 2004-01-08 Oncolytics Biotech Inc. Use of ribozymes in the detection of adventitious agents
JP3943048B2 (ja) * 2002-04-29 2007-07-11 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 組織の細胞dnaからの組込みウイルスの直接レスキュー及び増幅の方法
ES2323454T5 (es) * 2002-04-30 2012-11-14 Oncolytics Biotech Inc. Procedimiento mejorado de purificación de virus
CA2484398C (en) * 2002-05-09 2014-01-21 Oncolytics Biotech Inc. Method for reducing pain using oncolytic viruses
EP1944035A1 (de) 2002-05-09 2008-07-16 Oncolytics Biotech Inc. Verfahren zur Schmerzlinderung durch onkolytische Viren
NZ536062A (en) * 2002-05-10 2008-03-28 Oncolytics Biotech Inc Sensitization of neoplastic cells to radiation therapy with oncolytic viruses
US7901921B2 (en) 2004-10-22 2011-03-08 Oncolytics Biotech Inc. Viral purification methods
US7455063B2 (en) * 2005-06-17 2008-11-25 Nellcor Puritan Bennett Llc Adjustable gas delivery mask having a flexible gasket
US10668119B2 (en) 2005-08-01 2020-06-02 Virocure, Inc. Attenuated reovirus
CA2617600A1 (en) 2005-08-01 2007-09-07 University Technologies International, Inc. Attenuated reovirus
ES2551306T3 (es) * 2006-02-13 2015-11-17 Oncolytics Biotech Inc. Uso de inmunosupresión local de baja dosis para potenciar una terapia viral oncolítica
US8293498B2 (en) 2006-12-20 2012-10-23 Vanderbilt University System for generation of viable reovirus from cloned cDNA
WO2008127486A2 (en) * 2006-12-29 2008-10-23 Bacilligen, Inc. Replication-proficient dsrna capsids and uses thereof
KR101647843B1 (ko) 2007-03-12 2016-08-11 온콜리틱스 바이오테크 인코포레이티드 변형된 서열을 갖는 레오바이러스
US10369171B2 (en) 2007-03-13 2019-08-06 Virocure, Inc. Attenuated reoviruses for selection of cell populations
TW200909581A (en) * 2007-05-21 2009-03-01 Oncolytics Biotech Inc Mutant reoviruses and methods of making and using
WO2009052617A1 (en) * 2007-10-22 2009-04-30 Oncolytics Biotech Inc. Treatment regime for proliferative disorders
WO2009143610A1 (en) * 2008-05-27 2009-12-03 Oncolytics Biotech Inc. Modulating interstitial pressure and oncolytic viral delivery and distribution
MX2010012857A (es) * 2008-05-27 2010-12-20 Oncolytics Biotech Inc Supresion de produccion de citoquina proinflamatoria durante la terapia de reovirus oncolitico.
US9249195B2 (en) 2010-04-07 2016-02-02 Vanderbilt University Reovirus vaccines and methods of use therefor
CN102985536B (zh) 2010-04-14 2017-12-05 Emd密理博公司 生产高效价、高纯度的病毒母液的方法及使用其的方法
WO2012075379A2 (en) 2010-12-02 2012-06-07 Oncolytics Biotech Inc. Liquid viral formulations
CA2819236A1 (en) 2010-12-02 2012-06-07 Oncolytics Biotech Inc. Lyophilized viral formulations
ES2796950T3 (es) 2013-11-15 2020-11-30 Oncolytics Biotech Inc Virus oncolíticos y regímenes reforzados para tratamiento de cáncer

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070453A (en) * 1976-06-25 1978-01-24 Syntex (U.S.A.) Inc. Diploid porcine embryonic cell strains, cultures produced therefrom, and use of said cultures for production of vaccines
US4559229A (en) * 1982-07-20 1985-12-17 Research Foundation Avian proventriculitis vaccine
US5023252A (en) 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
JPS6344532A (ja) 1986-08-11 1988-02-25 Biseibutsu Kagaku Kenkyusho:Kk 豚のレオウイルス感染症ワクチン
US5658779A (en) 1992-03-20 1997-08-19 Ligochem, Inc. Method of adsorbing viruses from fluid compositions
JPH08214876A (ja) 1995-02-15 1996-08-27 Chemo Sero Therapeut Res Inst ウイルスの調製法
EP0968284B1 (de) 1996-11-20 2006-12-13 Introgen Therapeutics, Inc. Ein verbessertes verfahren zur produktion und reinigung von adenoviralen vektoren
CA2283894A1 (en) 1997-06-24 1998-12-30 Basf Aktiengesellschaft Method for producing 4,4' dihalogendiphenylsulfone
US6136307A (en) * 1997-08-13 2000-10-24 Oncolytics Biotech Inc. Reovirus for the treatment of cellular proliferative disorders
US6110461A (en) * 1997-08-13 2000-08-29 Oncolytics Biotech Inc. Reovirus for the treatment of neoplasia
AR028039A1 (es) 2000-05-03 2003-04-23 Oncolytics Biotech Inc Remocion de reovirus de celulas neoplasticas intermediadas por ras a partir de composiciones celulares mixtas
TWI289158B (en) * 2000-08-10 2007-11-01 Oncolytics Biotech Inc Method of producing infectious reovirus

Also Published As

Publication number Publication date
EP1309672A1 (de) 2003-05-14
WO2002012435A1 (en) 2002-02-14
TWI289158B (en) 2007-11-01
US7429485B2 (en) 2008-09-30
US20060165724A1 (en) 2006-07-27
DE60111747D1 (de) 2005-08-04
US7049127B2 (en) 2006-05-23
ZA200300410B (en) 2004-01-26
DE60133947D1 (de) 2008-06-19
NZ523510A (en) 2004-08-27
EP1586634A1 (de) 2005-10-19
MXPA03000846A (es) 2004-04-05
AU7562801A (en) 2002-02-18
US20020037576A1 (en) 2002-03-28
JP2006314336A (ja) 2006-11-24
US20030166253A1 (en) 2003-09-04
CA2415749C (en) 2009-05-12
DK1586634T3 (da) 2008-08-18
AU2001275628B2 (en) 2007-08-30
DK1309672T3 (da) 2005-10-10
US6703232B2 (en) 2004-03-09
JP2004505623A (ja) 2004-02-26
IL153847A0 (en) 2003-07-31
AR033993A1 (es) 2004-01-21
HK1082765A1 (en) 2006-06-16
ATE298788T1 (de) 2005-07-15
US20040126869A1 (en) 2004-07-01
EP1586634B1 (de) 2008-05-07
BR0113122A (pt) 2003-07-22
CA2415749A1 (en) 2002-02-14
US6528305B2 (en) 2003-03-04
ES2305940T3 (es) 2008-11-01
PT1586634E (pt) 2008-06-19
ES2241844T3 (es) 2005-11-01
EP1309672B1 (de) 2005-06-29
JP4009532B2 (ja) 2007-11-14
AU2001275628B8 (en) 2002-02-18
IL153847A (en) 2007-10-31
PT1309672E (pt) 2005-09-30
DE60111747T2 (de) 2006-04-27

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