DE60133947D1 - Methode zur Herstellung von infektiösem Reovirus - Google Patents

Methode zur Herstellung von infektiösem Reovirus

Info

Publication number
DE60133947D1
DE60133947D1 DE60133947T DE60133947T DE60133947D1 DE 60133947 D1 DE60133947 D1 DE 60133947D1 DE 60133947 T DE60133947 T DE 60133947T DE 60133947 T DE60133947 T DE 60133947T DE 60133947 D1 DE60133947 D1 DE 60133947D1
Authority
DE
Germany
Prior art keywords
producing infectious
infectious reovirus
reovirus
producing
infectious
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60133947T
Other languages
English (en)
Inventor
Matthew C Coffey
Bradley G Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncolytics Biotech Inc
Original Assignee
Oncolytics Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncolytics Biotech Inc filed Critical Oncolytics Biotech Inc
Application granted granted Critical
Publication of DE60133947D1 publication Critical patent/DE60133947D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/765—Reovirus; Rotavirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12051—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60133947T 2000-08-10 2001-07-20 Methode zur Herstellung von infektiösem Reovirus Expired - Lifetime DE60133947D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22402600P 2000-08-10 2000-08-10

Publications (1)

Publication Number Publication Date
DE60133947D1 true DE60133947D1 (de) 2008-06-19

Family

ID=22838987

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60133947T Expired - Lifetime DE60133947D1 (de) 2000-08-10 2001-07-20 Methode zur Herstellung von infektiösem Reovirus
DE2001611747 Expired - Lifetime DE60111747T2 (de) 2000-08-10 2001-07-20 Verfahren zur herstellung von infektiösen reoviren

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE2001611747 Expired - Lifetime DE60111747T2 (de) 2000-08-10 2001-07-20 Verfahren zur herstellung von infektiösen reoviren

Country Status (19)

Country Link
US (4) US6528305B2 (de)
EP (2) EP1309672B1 (de)
JP (2) JP4009532B2 (de)
AR (1) AR033993A1 (de)
AT (2) ATE394475T1 (de)
AU (2) AU7562801A (de)
BR (1) BR0113122A (de)
CA (1) CA2415749C (de)
DE (2) DE60133947D1 (de)
DK (2) DK1309672T3 (de)
ES (2) ES2241844T3 (de)
HK (1) HK1082765A1 (de)
IL (2) IL153847A0 (de)
MX (1) MXPA03000846A (de)
NZ (1) NZ523510A (de)
PT (2) PT1309672E (de)
TW (1) TWI289158B (de)
WO (1) WO2002012435A1 (de)
ZA (1) ZA200300410B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6545492B1 (en) * 1999-09-20 2003-04-08 Europaisches Laboratorium Fur Molekularbiologie (Embl) Multiple local probe measuring device and method
TWI289158B (en) * 2000-08-10 2007-11-01 Oncolytics Biotech Inc Method of producing infectious reovirus
NZ527525A (en) * 2001-03-16 2005-03-24 Oncolytics Biotech Inc Extraction of infectious virus which is suitable for clinical administration to mammals
US20040115170A1 (en) * 2001-11-30 2004-06-17 Brown Earl Garnet Oncolytic virus
US20040005546A1 (en) 2002-02-28 2004-01-08 Oncolytics Biotech Inc. Use of ribozymes in the detection of adventitious agents
CA2374388C (en) 2002-02-28 2005-07-12 Matthew C. Coffey The use of ribozymes in the detection of adventitious agents
WO2003093460A1 (en) * 2002-04-29 2003-11-13 The Trustees Of The University Of Pennsylvania Method for direct rescue and amplification of integrated viruses from cellular dna of tissues
DE60327069D1 (de) 2002-04-30 2009-05-20 Oncolytics Biotech Inc Verbesserte reinigungsmethode für viren
EP1944035A1 (de) 2002-05-09 2008-07-16 Oncolytics Biotech Inc. Verfahren zur Schmerzlinderung durch onkolytische Viren
JP5241059B2 (ja) * 2002-05-09 2013-07-17 オンコリティクス バイオテク，インコーポレーテッド 腫瘍崩壊ウイルスを使用して疼痛を軽減するための方法
US7198783B2 (en) * 2002-05-10 2007-04-03 Oncolytics Biotech Inc. Sensitization of neoplastic cells to radiation therapy with reovirus
US7901921B2 (en) 2004-10-22 2011-03-08 Oncolytics Biotech Inc. Viral purification methods
US7455063B2 (en) * 2005-06-17 2008-11-25 Nellcor Puritan Bennett Llc Adjustable gas delivery mask having a flexible gasket
WO2007099401A2 (en) 2005-08-01 2007-09-07 University Technologies International, Inc. Oncolytic attenuated reoviruses for treatment of proliferative disorders
US10668119B2 (en) 2005-08-01 2020-06-02 Virocure, Inc. Attenuated reovirus
WO2007093036A1 (en) * 2006-02-13 2007-08-23 Oncolytics Biotech Inc. Use of local immune suppression to enhance oncolytic viral therapy
US8293498B2 (en) 2006-12-20 2012-10-23 Vanderbilt University System for generation of viable reovirus from cloned cDNA
WO2008127486A2 (en) * 2006-12-29 2008-10-23 Bacilligen, Inc. Replication-proficient dsrna capsids and uses thereof
EP2132315B1 (de) 2007-03-12 2015-07-15 Oncolytics Biotech Inc. Reoviren mit modifizierten sequenzen
US10369171B2 (en) 2007-03-13 2019-08-06 Virocure, Inc. Attenuated reoviruses for selection of cell populations
AR066649A1 (es) * 2007-05-21 2009-09-02 Oncolytics Biotech Inc Reovirus mutantes y metodos de elaboracion y uso de los mismos
JP2011500608A (ja) * 2007-10-22 2011-01-06 オンコリティクス バイオテク，インコーポレーテッド 増殖性障害の治療レジメン
TW200950777A (en) * 2008-05-27 2009-12-16 Oncolytics Biotech Inc Abrogating proinflammatory cytokine production during oncolytic reovirus therapy
TW200951143A (en) * 2008-05-27 2009-12-16 Oncolytics Biotech Inc Modulating interstitial pressure and oncolytic viral delivery and distribution
WO2011126976A1 (en) 2010-04-07 2011-10-13 Vanderbilt University Reovirus vaccines and methods of use therefor
SG184833A1 (en) 2010-04-14 2012-11-29 Emd Millipore Corp Methods of producing high titer, high purity virus stocks and methods of use thereof
ES2630012T3 (es) * 2010-12-02 2017-08-17 Oncolytics Biotech Inc. Formulaciones virales liofilizadas
US9045728B2 (en) 2010-12-02 2015-06-02 Oncolytics Biotech Inc. Liquid viral formulations
US20160271193A1 (en) 2013-11-15 2016-09-22 Oncolytics Biotech Inc. Oncolytic viruses and increased cancer treatment regimens

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070453A (en) * 1976-06-25 1978-01-24 Syntex (U.S.A.) Inc. Diploid porcine embryonic cell strains, cultures produced therefrom, and use of said cultures for production of vaccines
US4559229A (en) * 1982-07-20 1985-12-17 Research Foundation Avian proventriculitis vaccine
US5023252A (en) 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
JPS6344532A (ja) 1986-08-11 1988-02-25 Biseibutsu Kagaku Kenkyusho:Kk 豚のレオウイルス感染症ワクチン
US5658779A (en) 1992-03-20 1997-08-19 Ligochem, Inc. Method of adsorbing viruses from fluid compositions
JPH08214876A (ja) 1995-02-15 1996-08-27 Chemo Sero Therapeut Res Inst ウイルスの調製法
ATE348155T1 (de) 1996-11-20 2007-01-15 Introgen Therapeutics Inc Ein verbessertes verfahren zur produktion und reinigung von adenoviralen vektoren
WO1998058907A1 (de) 1997-06-24 1998-12-30 Basf Aktiengesellschaft Verfahren zur herstellung von 4,4'-dihalogendiphenylsulfon
US6136307A (en) * 1997-08-13 2000-10-24 Oncolytics Biotech Inc. Reovirus for the treatment of cellular proliferative disorders
US6110461A (en) * 1997-08-13 2000-08-29 Oncolytics Biotech Inc. Reovirus for the treatment of neoplasia
AR028039A1 (es) 2000-05-03 2003-04-23 Oncolytics Biotech Inc Remocion de reovirus de celulas neoplasticas intermediadas por ras a partir de composiciones celulares mixtas
TWI289158B (en) * 2000-08-10 2007-11-01 Oncolytics Biotech Inc Method of producing infectious reovirus

Also Published As

Publication number Publication date
US6528305B2 (en) 2003-03-04
NZ523510A (en) 2004-08-27
US6703232B2 (en) 2004-03-09
AU7562801A (en) 2002-02-18
AR033993A1 (es) 2004-01-21
US7049127B2 (en) 2006-05-23
DK1586634T3 (da) 2008-08-18
EP1586634A1 (de) 2005-10-19
IL153847A (en) 2007-10-31
JP2004505623A (ja) 2004-02-26
EP1586634B1 (de) 2008-05-07
CA2415749A1 (en) 2002-02-14
ZA200300410B (en) 2004-01-26
MXPA03000846A (es) 2004-04-05
ATE298788T1 (de) 2005-07-15
EP1309672B1 (de) 2005-06-29
IL153847A0 (en) 2003-07-31
ES2241844T3 (es) 2005-11-01
DE60111747T2 (de) 2006-04-27
PT1586634E (pt) 2008-06-19
US20020037576A1 (en) 2002-03-28
AU2001275628B2 (en) 2007-08-30
ES2305940T3 (es) 2008-11-01
BR0113122A (pt) 2003-07-22
JP2006314336A (ja) 2006-11-24
US20040126869A1 (en) 2004-07-01
ATE394475T1 (de) 2008-05-15
CA2415749C (en) 2009-05-12
WO2002012435A1 (en) 2002-02-14
US20060165724A1 (en) 2006-07-27
US7429485B2 (en) 2008-09-30
JP4009532B2 (ja) 2007-11-14
EP1309672A1 (de) 2003-05-14
AU2001275628B8 (en) 2002-02-18
DK1309672T3 (da) 2005-10-10
PT1309672E (pt) 2005-09-30
TWI289158B (en) 2007-11-01
DE60111747D1 (de) 2005-08-04
US20030166253A1 (en) 2003-09-04
HK1082765A1 (en) 2006-06-16

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