AR066649A1 - Reovirus mutantes y metodos de elaboracion y uso de los mismos - Google Patents
Reovirus mutantes y metodos de elaboracion y uso de los mismosInfo
- Publication number
- AR066649A1 AR066649A1 ARP080102139A ARP080102139A AR066649A1 AR 066649 A1 AR066649 A1 AR 066649A1 AR P080102139 A ARP080102139 A AR P080102139A AR P080102139 A ARP080102139 A AR P080102139A AR 066649 A1 AR066649 A1 AR 066649A1
- Authority
- AR
- Argentina
- Prior art keywords
- reovirus
- methods
- elaboration
- mutants
- same
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Reivindicacion 1: Un reovirus mutante, CARACTERIZADO PORQUE dicho reovirus mutante comprende una primera mutacion, en donde dicha primera mutacion reduce la expresion de un polipéptido sigma3, elimina esencialmente la expresion de un polipéptido sigma3 o da como resultado la ausencia de un polipéptido sigma3 funcional. Reivindicacion 9: Una partícula subviral infecciosa (ISVP) de reovirus, CARACTERIZADA PORQUE fue manipulada genéticamente. También se proveen composiciones que incluyen reovirus mutantes y métodos de uso de dichos reovirus mutantes.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US93925507P | 2007-05-21 | 2007-05-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR066649A1 true AR066649A1 (es) | 2009-09-02 |
Family
ID=40031362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP080102139A AR066649A1 (es) | 2007-05-21 | 2008-05-20 | Reovirus mutantes y metodos de elaboracion y uso de los mismos |
Country Status (15)
Country | Link |
---|---|
US (1) | US20080292594A1 (es) |
EP (1) | EP2150613B1 (es) |
JP (1) | JP2010527593A (es) |
CN (2) | CN104195115A (es) |
AR (1) | AR066649A1 (es) |
AU (1) | AU2008253505B2 (es) |
CA (1) | CA2680661C (es) |
DK (1) | DK2150613T3 (es) |
ES (1) | ES2611455T3 (es) |
HK (1) | HK1136006A1 (es) |
IL (1) | IL200690A (es) |
MX (1) | MX2009012420A (es) |
TW (1) | TW200909581A (es) |
WO (1) | WO2008141448A1 (es) |
ZA (1) | ZA200907017B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0720624D0 (en) * | 2007-10-20 | 2007-11-28 | Academisch Ziekenhuis Leiden | Viral Modification |
CN101820892A (zh) * | 2007-10-22 | 2010-09-01 | 昂科利蒂克斯生物科技公司 | 增殖性疾病的治疗方案 |
TW200951143A (en) * | 2008-05-27 | 2009-12-16 | Oncolytics Biotech Inc | Modulating interstitial pressure and oncolytic viral delivery and distribution |
MX2010012857A (es) * | 2008-05-27 | 2010-12-20 | Oncolytics Biotech Inc | Supresion de produccion de citoquina proinflamatoria durante la terapia de reovirus oncolitico. |
SG190418A1 (en) | 2010-12-02 | 2013-07-31 | Oncolytics Biotech Inc | Liquid viral formulations |
AU2011336410B2 (en) | 2010-12-02 | 2015-01-22 | Oncolytics Biotech Inc. | Lyophilized viral formulations |
WO2015070323A1 (en) | 2013-11-15 | 2015-05-21 | Oncolytics Biotech Inc. | Oncolytic viruses and increased cancer treatment regimens |
EP3417866B1 (en) | 2016-02-16 | 2020-12-23 | Osaka University | Medicinal composition for treating fibrosis |
KR20210098202A (ko) * | 2020-01-31 | 2021-08-10 | 바이로큐어 주식회사 | 레오바이러스를 유효성분으로 포함하는 대장염의 예방 또는 치료용 조성물 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4554101A (en) * | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
US5023252A (en) * | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
US6110461A (en) * | 1997-08-13 | 2000-08-29 | Oncolytics Biotech Inc. | Reovirus for the treatment of neoplasia |
US6136307A (en) * | 1997-08-13 | 2000-10-24 | Oncolytics Biotech Inc. | Reovirus for the treatment of cellular proliferative disorders |
US6565831B1 (en) * | 1999-02-24 | 2003-05-20 | Oncolytics Biotech Inc. | Methods for preventing reovirus recognition for the treatment of cellular proliferative disorders |
EP1098961B1 (en) * | 1998-06-12 | 2008-01-16 | Mount Sinai School Of Medicine Of The City University Of New York | Interferon inducing genetically engineered attenuated viruses |
TWI289158B (en) * | 2000-08-10 | 2007-11-01 | Oncolytics Biotech Inc | Method of producing infectious reovirus |
EP2189162B1 (en) * | 2000-11-09 | 2013-11-27 | Oncolytics Biotech Inc. | Methods for the treatment of cellular proliferative disorders |
WO2002074940A1 (en) * | 2001-03-16 | 2002-09-26 | Oncolytics Biotech, Inc. | Method of extracting virus from cell culture |
US7163678B2 (en) * | 2002-11-07 | 2007-01-16 | Oncolytics Biotech Inc. | Reovirus for the treatment of ral-mediated cellular proliferative disorders |
WO2005111200A1 (en) * | 2004-05-17 | 2005-11-24 | Universite De Montreal | Novel strains of reoviruses and methods of uses thereof |
WO2007099401A2 (en) * | 2005-08-01 | 2007-09-07 | University Technologies International, Inc. | Oncolytic attenuated reoviruses for treatment of proliferative disorders |
-
2008
- 2008-05-20 TW TW097118468A patent/TW200909581A/zh unknown
- 2008-05-20 AR ARP080102139A patent/AR066649A1/es unknown
- 2008-05-21 US US12/124,522 patent/US20080292594A1/en not_active Abandoned
- 2008-05-21 MX MX2009012420A patent/MX2009012420A/es active IP Right Grant
- 2008-05-21 WO PCT/CA2008/000964 patent/WO2008141448A1/en active Application Filing
- 2008-05-21 DK DK08748334.3T patent/DK2150613T3/en active
- 2008-05-21 JP JP2010508676A patent/JP2010527593A/ja active Pending
- 2008-05-21 ES ES08748334.3T patent/ES2611455T3/es active Active
- 2008-05-21 CA CA2680661A patent/CA2680661C/en active Active
- 2008-05-21 CN CN201410339446.7A patent/CN104195115A/zh active Pending
- 2008-05-21 EP EP08748334.3A patent/EP2150613B1/en active Active
- 2008-05-21 CN CN200880016669A patent/CN101679953A/zh active Pending
- 2008-05-21 AU AU2008253505A patent/AU2008253505B2/en active Active
-
2009
- 2009-09-02 IL IL200690A patent/IL200690A/en active IP Right Grant
- 2009-10-08 ZA ZA2009/07017A patent/ZA200907017B/en unknown
-
2010
- 2010-02-24 HK HK10101956.8A patent/HK1136006A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
JP2010527593A (ja) | 2010-08-19 |
EP2150613B1 (en) | 2016-10-19 |
IL200690A0 (en) | 2011-08-01 |
CA2680661A1 (en) | 2008-11-27 |
IL200690A (en) | 2014-02-27 |
CA2680661C (en) | 2018-05-29 |
TW200909581A (en) | 2009-03-01 |
CN104195115A (zh) | 2014-12-10 |
WO2008141448A1 (en) | 2008-11-27 |
DK2150613T3 (en) | 2017-01-30 |
HK1136006A1 (zh) | 2010-06-18 |
ES2611455T3 (es) | 2017-05-09 |
ZA200907017B (en) | 2010-12-29 |
AU2008253505A1 (en) | 2008-11-27 |
CN101679953A (zh) | 2010-03-24 |
MX2009012420A (es) | 2009-12-09 |
EP2150613A1 (en) | 2010-02-10 |
AU2008253505B2 (en) | 2014-09-04 |
EP2150613A4 (en) | 2011-01-19 |
US20080292594A1 (en) | 2008-11-27 |
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Legal Events
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FB | Suspension of granting procedure |