ATE392431T1 - Pth2 rezeptor selektive verbindungen - Google Patents
Pth2 rezeptor selektive verbindungenInfo
- Publication number
- ATE392431T1 ATE392431T1 AT99918938T AT99918938T ATE392431T1 AT E392431 T1 ATE392431 T1 AT E392431T1 AT 99918938 T AT99918938 T AT 99918938T AT 99918938 T AT99918938 T AT 99918938T AT E392431 T1 ATE392431 T1 AT E392431T1
- Authority
- AT
- Austria
- Prior art keywords
- selective compounds
- receptor selective
- abnormal
- pth2 receptor
- pth2
- Prior art date
Links
- 102100030869 Parathyroid hormone 2 receptor Human genes 0.000 title abstract 2
- 101710149426 Parathyroid hormone 2 receptor Proteins 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 230000002159 abnormal effect Effects 0.000 abstract 3
- 208000007466 Male Infertility Diseases 0.000 abstract 1
- 108700020797 Parathyroid Hormone-Related Proteins 0.000 abstract 1
- 108090000445 Parathyroid hormone Proteins 0.000 abstract 1
- 102000043299 Parathyroid hormone-related Human genes 0.000 abstract 1
- 230000033228 biological regulation Effects 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000006870 function Effects 0.000 abstract 1
- 230000013632 homeostatic process Effects 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 230000004203 pancreatic function Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7295698A | 1998-05-05 | 1998-05-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE392431T1 true ATE392431T1 (de) | 2008-05-15 |
Family
ID=22110801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99918938T ATE392431T1 (de) | 1998-05-05 | 1999-05-03 | Pth2 rezeptor selektive verbindungen |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7531621B1 (enExample) |
| EP (1) | EP1075491B1 (enExample) |
| JP (1) | JP4460157B2 (enExample) |
| AT (1) | ATE392431T1 (enExample) |
| AU (1) | AU3673699A (enExample) |
| CA (1) | CA2327509A1 (enExample) |
| DE (1) | DE69938548T2 (enExample) |
| ES (1) | ES2302374T3 (enExample) |
| HU (1) | HUP0300891A2 (enExample) |
| NO (1) | NO20005556L (enExample) |
| PL (1) | PL344645A1 (enExample) |
| WO (1) | WO1999057139A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK40599A3 (en) | 1996-09-26 | 2000-06-12 | Chugai Pharmaceutical Co Ltd | Antibody against human parathormone related peptides |
| UA74130C2 (uk) | 1997-05-15 | 2005-11-15 | Чугаі Сейяку Кабусікі Кайся | ЗАСТОСУВАННЯ АНТИТІЛА ПРОТИ БІЛКА, СПОРІДНЕНОГО З ПАРАТИРЕОЇДНИМ ГОРМОНОМ (PTHrP), АБО ЙОГО ФУНКЦІОНАЛЬНО АКТИВНОГО ФРАГМЕНТА І/АБО ЙОГО МОДИФІКОВАНОГО ФРАГМЕНТА ДЛЯ ВИРОБНИЦТВА ЛІКАРСЬКОГО ЗАСОБУ ДЛЯ ПРОФІЛАКТИКИ АБО ЛІКУВАННЯ КАХЕКСІЇ |
| TWI255718B (en) | 1999-07-02 | 2006-06-01 | Chugai Pharmaceutical Co Ltd | Ameliorative agent for low vasopressin concentration |
| CA2373885A1 (en) * | 1999-07-02 | 2001-01-11 | Chugai Seiyaku Kabushiki Kaisha | Therapeutic agent for diseases caused by pth or pthrp |
| EP1987842A1 (en) | 2000-04-28 | 2008-11-05 | Chugai Seiyaku Kabushiki Kaisha | Cell proliferation inhibitor |
| AU2001292905A1 (en) * | 2000-09-19 | 2002-04-02 | Curagen Corporation | Method of identifying osteoregenerative agents using differential gene expression |
| WO2004071396A2 (en) * | 2003-02-17 | 2004-08-26 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with parathyroid hormone receptor 2 (pthr2) |
| CN101522709B (zh) | 2006-10-13 | 2013-03-20 | 伊莱利利公司 | 作为pth受体调节剂的聚乙二醇化的pth及其用途 |
| JP5711966B2 (ja) | 2007-08-01 | 2015-05-07 | ザ ジェネラル ホスピタル コーポレイション | Ｇタンパク質共役受容体および関連組成物を使用するスクリーニング方法 |
| MX358161B (es) | 2010-05-13 | 2018-08-06 | The General Hospital Corp Star | Analogos de hormona paratiroidea y usos para los mismos. |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0293158A3 (en) | 1987-05-26 | 1990-05-09 | Merck & Co. Inc. | Parathyroid hormone antagonists |
| US5001223A (en) * | 1987-05-26 | 1991-03-19 | Merck & Co., Inc. | Parathyroid hormone antagonists with enhanced metabolic properties |
| US5527772A (en) | 1987-10-20 | 1996-06-18 | Holick; Michael F. | Regulation of cell proliferation and differentiation using peptides |
| US4968669A (en) | 1988-05-09 | 1990-11-06 | Merck & Co., Inc. | Parathyroid hormone antagonists |
| DE68921665T2 (de) | 1988-05-09 | 1995-09-21 | Merck & Co Inc | Hemmer vom flüssigen kalziumerhöhenden Faktor. |
| CA2040264A1 (en) | 1990-04-12 | 1991-10-13 | Tatsuhiko Kanmera | Parathyroid hormone antagonists |
| US5087562A (en) | 1990-04-25 | 1992-02-11 | Merck & Co., Inc. | Humoral hypercalcemic factor antagonists with modification at position 13 . . . |
| US5093233A (en) | 1990-04-25 | 1992-03-03 | Merck & Co., Inc. | Antagonists with position 13 modification |
| US5149779A (en) | 1990-07-26 | 1992-09-22 | Merck & Co., Inc. | Humoral hypercalcemic factor antagonists |
| JPH0532696A (ja) | 1990-09-28 | 1993-02-09 | Takeda Chem Ind Ltd | 副甲状腺ホルモン誘導体 |
| CA2098283A1 (en) | 1990-12-21 | 1992-06-22 | Richard P. Bozzato | Oxidation resistant variants of parathyroid hormone |
| DE4203040A1 (de) | 1992-02-04 | 1993-08-05 | Boehringer Mannheim Gmbh | Neue parathormonfragmente, deren herstellung und diese enthaltende arzneimittel |
| US5589452A (en) | 1992-07-14 | 1996-12-31 | Syntex (U.S.A.) Inc. | Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis |
| AU672790B2 (en) | 1992-07-15 | 1996-10-17 | Novartis Ag | Variants of parathyroid hormone and its fragments |
| CA2126299C (en) * | 1994-06-20 | 2000-12-12 | Gordon E. Willick | Parathyroid hormone analogues for the treatment of osteoporosis |
| US5747456A (en) | 1994-12-19 | 1998-05-05 | Beth Israel Deaconess Medical Center | Continuous low-dose administration of parathyroid hormone or its agonist |
| US5717062A (en) | 1995-06-07 | 1998-02-10 | Beth Israel Hospital Association | Cyclic analogs of PTH and PTHrP |
| US5955574A (en) * | 1995-07-13 | 1999-09-21 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A. | Analogs of parathyroid hormone |
| US5723577A (en) | 1995-07-13 | 1998-03-03 | Biomeasure Inc. | Analogs of parathyroid hormone |
| US5969095A (en) | 1995-07-13 | 1999-10-19 | Biomeasure, Inc. | Analogs of parathyroid hormone |
| JP3259011B2 (ja) * | 1995-08-02 | 2002-02-18 | ミヤチテクノス株式会社 | インバータ式抵抗溶接制御方法及び装置 |
| ATE304020T1 (de) | 1996-07-31 | 2005-09-15 | Gen Hospital Corp | Parathyroidhormon-verwandthe peptidanaloge |
-
1999
- 1999-05-03 EP EP99918938A patent/EP1075491B1/en not_active Expired - Lifetime
- 1999-05-03 US US09/674,597 patent/US7531621B1/en not_active Expired - Fee Related
- 1999-05-03 CA CA002327509A patent/CA2327509A1/en not_active Abandoned
- 1999-05-03 AT AT99918938T patent/ATE392431T1/de not_active IP Right Cessation
- 1999-05-03 PL PL99344645A patent/PL344645A1/xx not_active Application Discontinuation
- 1999-05-03 WO PCT/US1999/009521 patent/WO1999057139A2/en not_active Ceased
- 1999-05-03 HU HU0300891A patent/HUP0300891A2/hu unknown
- 1999-05-03 AU AU36736/99A patent/AU3673699A/en not_active Abandoned
- 1999-05-03 DE DE69938548T patent/DE69938548T2/de not_active Expired - Lifetime
- 1999-05-03 ES ES99918938T patent/ES2302374T3/es not_active Expired - Lifetime
- 1999-05-03 JP JP2000547108A patent/JP4460157B2/ja not_active Expired - Fee Related
-
2000
- 2000-11-03 NO NO20005556A patent/NO20005556L/no not_active Application Discontinuation
-
2009
- 2009-03-27 US US12/413,303 patent/US20090226477A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US7531621B1 (en) | 2009-05-12 |
| EP1075491B1 (en) | 2008-04-16 |
| WO1999057139A3 (en) | 2000-02-03 |
| DE69938548T2 (de) | 2009-06-18 |
| JP4460157B2 (ja) | 2010-05-12 |
| HUP0300891A2 (hu) | 2003-07-28 |
| DE69938548D1 (de) | 2008-05-29 |
| CA2327509A1 (en) | 1999-11-11 |
| PL344645A1 (en) | 2001-11-19 |
| WO1999057139A2 (en) | 1999-11-11 |
| NO20005556D0 (no) | 2000-11-03 |
| US20090226477A1 (en) | 2009-09-10 |
| AU3673699A (en) | 1999-11-23 |
| NO20005556L (no) | 2001-01-03 |
| JP2002513801A (ja) | 2002-05-14 |
| EP1075491A2 (en) | 2001-02-14 |
| ES2302374T3 (es) | 2008-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |