ATE386075T1 - Hydrogel-formendes system mit hydrophoben und hydrophilen komponenten - Google Patents

Hydrogel-formendes system mit hydrophoben und hydrophilen komponenten

Info

Publication number
ATE386075T1
ATE386075T1 AT00917865T AT00917865T ATE386075T1 AT E386075 T1 ATE386075 T1 AT E386075T1 AT 00917865 T AT00917865 T AT 00917865T AT 00917865 T AT00917865 T AT 00917865T AT E386075 T1 ATE386075 T1 AT E386075T1
Authority
AT
Austria
Prior art keywords
hydrophobic
hydrogel
hydrophilic components
shaping system
unsaturated group
Prior art date
Application number
AT00917865T
Other languages
German (de)
English (en)
Inventor
Chee-Youb Won
Yeli Zhang
Chih-Chang Chu
Original Assignee
Cornell Res Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cornell Res Foundation Inc filed Critical Cornell Res Foundation Inc
Application granted granted Critical
Publication of ATE386075T1 publication Critical patent/ATE386075T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/02—Dextran; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/64—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63
    • C08G18/6484—Polysaccharides and derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/81—Unsaturated isocyanates or isothiocyanates
    • C08G18/8108—Unsaturated isocyanates or isothiocyanates having only one isocyanate or isothiocyanate group
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C08L67/06—Unsaturated polyesters
    • C08L67/07—Unsaturated polyesters having terminal carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2210/00—Compositions for preparing hydrogels
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S525/00—Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S525/937—Utility as body contact e.g. implant, contact lens or I.U.D.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Colloid Chemistry (AREA)
  • Graft Or Block Polymers (AREA)
AT00917865T 1999-04-12 2000-03-20 Hydrogel-formendes system mit hydrophoben und hydrophilen komponenten ATE386075T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12880399P 1999-04-12 1999-04-12

Publications (1)

Publication Number Publication Date
ATE386075T1 true ATE386075T1 (de) 2008-03-15

Family

ID=22437052

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00917865T ATE386075T1 (de) 1999-04-12 2000-03-20 Hydrogel-formendes system mit hydrophoben und hydrophilen komponenten

Country Status (10)

Country Link
US (4) US6388047B1 (enExample)
EP (1) EP1168934B1 (enExample)
JP (1) JP4558213B2 (enExample)
AT (1) ATE386075T1 (enExample)
AU (1) AU3877200A (enExample)
CA (1) CA2368617C (enExample)
DE (1) DE60038010T2 (enExample)
DK (1) DK1168934T3 (enExample)
ES (1) ES2298135T3 (enExample)
WO (1) WO2000060956A1 (enExample)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3877200A (en) 1999-04-12 2000-11-14 Cornell Research Foundation Inc. Hydrogel-forming system with hydrophobic and hydrophilic components
US6716445B2 (en) * 1999-04-12 2004-04-06 Cornell Research Foundation, Inc. Hydrogel entrapping therapeutic agent and stent with coating comprising this
AU2002316340B2 (en) * 2001-08-02 2006-09-07 Cornell Research Foundation, Inc. Biodegradable polyhydric alcohol esters
US20050064587A1 (en) * 2001-09-07 2005-03-24 Lawrence Rosenberg Pancreatic small cells and uses thereof
US7037983B2 (en) 2002-06-14 2006-05-02 Kimberly-Clark Worldwide, Inc. Methods of making functional biodegradable polymers
JP3742842B2 (ja) * 2002-06-17 2006-02-08 独立行政法人産業技術総合研究所 生分解性ポリ乳酸樹脂組成物
EP1536746B1 (en) * 2002-06-24 2013-05-08 Incept, LLC Fillers and methods for displacing tissues to improve radiological outcomes
AU2002950340A0 (en) * 2002-07-23 2002-09-12 Commonwealth Scientific And Industrial Research Organisation Biodegradable polyurethane/urea compositions
EP1530600B1 (en) * 2002-08-09 2007-03-14 Ottawa Health Research Institute Bio-synthetic matrix and uses thereof
AU2003270593A1 (en) * 2002-09-13 2004-04-30 Ocular Sciences, Inc. Devices and methods for improving vision
AU2003294258B2 (en) * 2003-01-16 2009-05-28 Cornell Research Foundation, Inc. Partially biodegradable temperature and pH sensitive hydrogel
WO2004085712A2 (en) 2003-03-24 2004-10-07 Penn State Research Foundation Multi-functional polymeric materials and their uses
WO2005041987A1 (en) * 2003-10-29 2005-05-12 Gentis, Inc. Polymerizable emulsions for tissue engineering
EP1691854B1 (en) * 2003-11-03 2011-09-14 Medtronic, Inc. Hydrogel providing cell-specific ingrowth
MY144221A (en) * 2004-03-03 2011-08-15 Polynovo Biomaterials Pty Ltd Biocompatible polymer compositions for dual or multistaged curing.
EP1735378A1 (en) * 2004-03-17 2006-12-27 Ciphergen Biosystems, Inc. Photocrosslinked hydrogel blend surface coatings
WO2005097223A1 (en) 2004-03-26 2005-10-20 Surmodics, Inc. Composition and method for preparing biocompatible surfaces
GB0407661D0 (en) * 2004-04-03 2004-05-05 Univ Hull Liquid crystalline interpenetrating polymer networks
JP4599550B2 (ja) * 2004-04-09 2010-12-15 国立大学法人 東京医科歯科大学 ナノゲル工学によるハイブリッドゲルの調製とバイオマテリアル応用
JP5026956B2 (ja) * 2004-05-12 2012-09-19 サーモディクス，インコーポレイティド 医療用具のための天然生分解性多糖コーティング
KR20070055422A (ko) 2004-05-20 2007-05-30 쿠퍼비젼,인코포레이티드 시력 향상을 위한 각막 온레이 및 파면 수차 보정
US8246993B2 (en) 2004-06-10 2012-08-21 Cytogel Pharma, Llc Advantageous hydrogel composition
US7446131B1 (en) 2004-06-10 2008-11-04 The United States Of America As Represented By The Secretary Of Agriculture Porous polymeric matrices made of natural polymers and synthetic polymers and optionally at least one cation and methods of making
US20060013886A1 (en) 2004-06-28 2006-01-19 Daqing Wu Injectable microspheres
US7235592B2 (en) * 2004-10-12 2007-06-26 Zimmer Gmbh PVA hydrogel
WO2006091706A1 (en) * 2005-02-23 2006-08-31 Zimmer Technology, Inc. Blend hydrogels and methods of making
US20060222596A1 (en) 2005-04-01 2006-10-05 Trivascular, Inc. Non-degradable, low swelling, water soluble radiopaque hydrogel polymer
US7964696B2 (en) * 2005-09-20 2011-06-21 Polynovo Biomaterials Pty Limited Chain extenders
WO2007035865A1 (en) * 2005-09-21 2007-03-29 Surmodics, Inc. Coatings and articles including natural biodegradable polysaccharides
ATE540705T1 (de) * 2005-09-21 2012-01-15 Surmodics Inc Überzüge und artikel mit natürlichen biologisch abbaubaren polysacchariden
US20070098799A1 (en) * 2005-10-28 2007-05-03 Zimmer, Inc. Mineralized Hydrogels and Methods of Making and Using Hydrogels
WO2007067697A2 (en) * 2005-12-07 2007-06-14 Zimmer, Inc. Methods of bonding or modifying hydrogels using irradiation
US20070141108A1 (en) * 2005-12-20 2007-06-21 Zimmer, Inc. Fiber-reinforced water-swellable articles
JP2007177244A (ja) * 2005-12-22 2007-07-12 Zimmer Inc ペルフルオロシクロブタン架橋ハイドロゲル
WO2007092550A2 (en) * 2006-02-08 2007-08-16 Coopervision Inc. Corneal onlays and related methods
DE602007004086D1 (de) * 2006-03-14 2010-02-11 Novozymes Biopharma Dk As Acrylierte hyaluronsäure
US8110242B2 (en) * 2006-03-24 2012-02-07 Zimmer, Inc. Methods of preparing hydrogel coatings
US8795709B2 (en) 2006-03-29 2014-08-05 Incept Llc Superabsorbent, freeze dried hydrogels for medical applications
US20070232762A1 (en) * 2006-03-31 2007-10-04 Depuy Products, Inc. Bearing material of medical implant having reduced wear rate and method for reducing wear rate
US7812098B2 (en) * 2006-03-31 2010-10-12 Depuy Products, Inc. Bearing material of medical implant having reduced wear rate and method for reducing wear rate
US7883520B2 (en) * 2006-04-10 2011-02-08 Forsight Labs, Llc Corneal epithelial pocket formation systems, components and methods
US7872068B2 (en) * 2006-05-30 2011-01-18 Incept Llc Materials formable in situ within a medical device
WO2008014561A1 (en) * 2006-08-02 2008-02-07 Polynovo Biomaterials Pty Ltd Biocompatible polymer compositions
US20080075785A1 (en) * 2006-09-22 2008-03-27 San-Laung Chow Controlled release hydrogel formulation
US20110165236A1 (en) * 2006-09-22 2011-07-07 Biokey, Inc. Controlled release hydrogel formulation
US20080154241A1 (en) * 2006-12-07 2008-06-26 Burkstrand Michael J Latent stabilization of bioactive agents releasable from implantable medical articles
US9125807B2 (en) 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
US7731988B2 (en) * 2007-08-03 2010-06-08 Zimmer, Inc. Multi-polymer hydrogels
US20090043398A1 (en) * 2007-08-09 2009-02-12 Zimmer, Inc. Method of producing gradient articles by centrifugation molding or casting
US20110136935A1 (en) * 2007-08-30 2011-06-09 National University Of Singapore Bone and/or dental cement composition and uses thereof
US8062739B2 (en) * 2007-08-31 2011-11-22 Zimmer, Inc. Hydrogels with gradient
JP5600062B2 (ja) * 2007-10-03 2014-10-01 ポリィノボ バイオマテリアルズ ピーティワイ リミテッド 高弾性率ポリウレタン及びポリウレタン／尿素組成物
US7947784B2 (en) 2007-11-16 2011-05-24 Zimmer, Inc. Reactive compounding of hydrogels
US8034362B2 (en) * 2008-01-04 2011-10-11 Zimmer, Inc. Chemical composition of hydrogels for use as articulating surfaces
WO2009120361A2 (en) 2008-03-28 2009-10-01 Surmodics, Inc. Insertable medical devices having microparticulate-associated elastic substrates and methods for drug delivery
CA2723192A1 (en) 2008-05-07 2009-11-12 Surmodics, Inc. Delivery of nucleic acid complexes from particles
US20100087920A1 (en) * 2008-10-07 2010-04-08 Forsight Labs, Llc Corneal Onlay Lenses and Related Methods for Improving Vision of Presbyopic Patients
AU2010213612B2 (en) 2009-02-12 2015-04-30 Incept, Llc Drug delivery through hydrogel plugs
WO2010129510A2 (en) 2009-05-04 2010-11-11 Incept. Llc Biomaterials for track and puncture closure
JP2012235797A (ja) 2009-09-18 2012-12-06 Terumo Corp ステント
WO2011057131A1 (en) 2009-11-09 2011-05-12 Spotlight Technology Partners Llc Polysaccharide based hydrogels
JP2013509963A (ja) 2009-11-09 2013-03-21 スポットライト テクノロジー パートナーズ エルエルシー 断片化ヒドロゲル
CA3149284A1 (en) 2009-12-15 2011-07-14 Incept, Llc Implants and biodegradable fiducial markers
WO2011146922A2 (en) 2010-05-21 2011-11-24 Cytogel Pharma, Llc Materials and methods for treatment of inflammation
US8961501B2 (en) 2010-09-17 2015-02-24 Incept, Llc Method for applying flowable hydrogels to a cornea
US8901092B2 (en) 2010-12-29 2014-12-02 Surmodics, Inc. Functionalized polysaccharides for active agent delivery
WO2013012924A2 (en) 2011-07-18 2013-01-24 President And Fellows Of Harvard College Engineered microbe-targeting molecules and uses thereof
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
RU2521194C2 (ru) * 2011-11-16 2014-06-27 Общество с ограниченной ответственностью предприятие "Репер" Матрица для клеточной трансплантологии
AU2012347926B2 (en) 2011-12-05 2018-03-15 Incept, Llc Medical organogel processes and compositions
CN105188667A (zh) * 2013-03-27 2015-12-23 佛多斯大学医学研究中心(C·H·U·V) 用于治疗和/或预防再狭窄的药物制剂
EP3848045A1 (en) 2013-05-21 2021-07-14 President and Fellows of Harvard College Engineered heme-binding compositions and uses thereof
WO2015095604A2 (en) 2013-12-18 2015-06-25 President And Fellows Of Harvard College Methods and assays relating to circulating tumor cells
WO2016040347A2 (en) 2014-09-08 2016-03-17 University Of Iowa Research Foundation Microrna inhibitor system and methods of use thereof
WO2017024114A1 (en) 2015-08-06 2017-02-09 President And Fellows Of Harvard College Improved microbe-binding molecules and uses thereof
US10273476B2 (en) 2016-04-30 2019-04-30 University Of Iowa Research Foundation MicroRNA-200 based approaches for modulating bone formation inhibition and bone regeneration
WO2018112187A1 (en) * 2016-12-16 2018-06-21 E. I. Du Pont De Nemours And Company Amphiphilic polysaccharide derivatives and compositions comprising same
CN106913915B (zh) * 2017-04-21 2019-05-31 浙江大学 一种自愈合支架复合涂层及其制备方法和应用
CN107216450B (zh) * 2017-04-21 2019-06-11 浙江大学 一种自愈合抗菌涂层及其制备方法和应用
US10975121B2 (en) 2017-06-24 2021-04-13 Cytogel Pharma, Llc Analgesic mu-opioid receptor binding peptide pharmaceutical formulations and uses thereof
CN110108537B (zh) * 2018-02-01 2020-08-25 中国科学技术大学 一种用于生物组织包埋的包埋剂和包埋方法
CN108359054A (zh) * 2018-02-10 2018-08-03 西北大学 一种葡萄糖敏感型全互穿网络水凝胶及其制备方法
CN116496475B (zh) * 2023-06-26 2023-09-22 海杰亚（北京）医疗器械有限公司 用于栓塞微球的可降解交联剂、可降解栓塞微球及其制备方法和药物组合物

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002173A (en) 1974-07-23 1977-01-11 International Paper Company Diester crosslinked polyglucan hydrogels and reticulated sponges thereof
US4032488A (en) * 1975-10-03 1977-06-28 Meito Sangyo Kabushiki Kaisha Dextran ester-olefin compound copolymer and process for preparing same
SU729197A1 (ru) * 1977-07-05 1980-04-25 Ордена Ленина Институт Элементоорганических Соединений Ан Ссср Сшитые сополимеры хитозана
US4277582A (en) * 1978-03-03 1981-07-07 Ciba-Geigy Corporation Water-insoluble hydrophilic copolymers
GB8418772D0 (en) 1984-07-24 1984-08-30 Geistlich Soehne Ag Chemical substances
US4857602A (en) * 1986-09-05 1989-08-15 American Cyanamid Company Bioabsorbable surgical suture coating
US4938763B1 (en) 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5626863A (en) 1992-02-28 1997-05-06 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5529914A (en) * 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
US5410016A (en) 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5210111A (en) * 1991-08-22 1993-05-11 Ciba-Geigy Corporation Crosslinked hydrogels derived from hydrophilic polymer backbones
US5837747A (en) 1991-10-29 1998-11-17 Vivorx, Inc. Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release
CA2107683C (en) 1992-02-13 2004-07-20 Dale G. Swan Immobilization of chemical species in crosslinked matrices
US5573934A (en) 1992-04-20 1996-11-12 Board Of Regents, The University Of Texas System Gels for encapsulation of biological materials
NZ249770A (en) 1992-02-28 1996-09-25 Univ Texas Biodegradable, polymerisable, substantially water soluble macromer comprising at least one water soluble region, at least one degradable region and at least two free radical polymerisable regions separated by at least one degradable region
IT1260154B (it) 1992-07-03 1996-03-28 Lanfranco Callegaro Acido ialuronico e suoi derivati in polimeri interpenetranti (ipn)
US5514379A (en) 1992-08-07 1996-05-07 The General Hospital Corporation Hydrogel compositions and methods of use
DK0624166T3 (da) 1992-11-30 1997-10-06 Ciba Geigy Ag Polymeriserbare carbohydratestere, polymerer fremstillet deraf og deres anvendelse
KR0141431B1 (ko) 1994-05-17 1998-07-01 김상웅 생분해성 하이드로겔 고분자
TW291481B (en) * 1994-10-27 1996-11-21 Novartis Erfind Verwalt Gmbh Poly-unsaturated carbohydrate derivatives, polymers thereof and their use
US5607686A (en) 1994-11-22 1997-03-04 United States Surgical Corporation Polymeric composition
US5540929A (en) 1995-03-08 1996-07-30 Board Of Trustees Operating Michigan State University Polysaccharides grafted with aliphatic polyesters derived from cyclic esters
US5900245A (en) 1996-03-22 1999-05-04 Focal, Inc. Compliant tissue sealants
CA2228118A1 (en) * 1995-07-28 1997-02-13 Focal, Inc. Multiblock biodegradable hydrogels for use as controlled release agents for drugs delivery and tissue treatments agents
JP3572144B2 (ja) * 1996-05-31 2004-09-29 名糖産業株式会社 デキストランエステル共重合体
US5854382A (en) * 1997-08-18 1998-12-29 Meadox Medicals, Inc. Bioresorbable compositions for implantable prostheses
DE69839054T2 (de) * 1997-09-03 2009-01-15 The Regents Of The University Of California, Oakland Biomimetrische materialien vom hydrogel-typ
ES2241314T3 (es) 1998-08-31 2005-10-16 Cornell Research Foundation, Inc. Monoesteres de acido maleico-dextrano e hidroogeles basados en ellos.
AU3877200A (en) 1999-04-12 2000-11-14 Cornell Research Foundation Inc. Hydrogel-forming system with hydrophobic and hydrophilic components
US6716445B2 (en) 1999-04-12 2004-04-06 Cornell Research Foundation, Inc. Hydrogel entrapping therapeutic agent and stent with coating comprising this
JP2003508113A (ja) * 1999-09-02 2003-03-04 アルコン，インコーポレイテッド 外科移植片用の疎水的に結合した親水性被覆組成物
US6503538B1 (en) 2000-08-30 2003-01-07 Cornell Research Foundation, Inc. Elastomeric functional biodegradable copolyester amides and copolyester urethanes
AU2002316340B2 (en) 2001-08-02 2006-09-07 Cornell Research Foundation, Inc. Biodegradable polyhydric alcohol esters

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EP1168934A4 (en) 2004-12-08
WO2000060956A1 (en) 2000-10-19
CA2368617C (en) 2010-03-16
US6709668B2 (en) 2004-03-23
US6583219B2 (en) 2003-06-24
US20040122165A1 (en) 2004-06-24
DE60038010T2 (de) 2009-03-05
AU3877200A (en) 2000-11-14
JP2002541308A (ja) 2002-12-03
CA2368617A1 (en) 2000-10-19
EP1168934B1 (en) 2008-02-13
JP4558213B2 (ja) 2010-10-06
US6388047B1 (en) 2002-05-14
US20020161169A1 (en) 2002-10-31
US6916857B2 (en) 2005-07-12
DK1168934T3 (da) 2008-05-13
DE60038010D1 (de) 2008-03-27
ES2298135T3 (es) 2008-05-16
US20030125509A1 (en) 2003-07-03
EP1168934A1 (en) 2002-01-09

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