ATE373012T1 - An caml bindender lymphozyteoberflächenrezeptor, nukleinsäuren die dafür kodieren und verfahren zur verwendung - Google Patents
An caml bindender lymphozyteoberflächenrezeptor, nukleinsäuren die dafür kodieren und verfahren zur verwendungInfo
- Publication number
- ATE373012T1 ATE373012T1 AT98908948T AT98908948T ATE373012T1 AT E373012 T1 ATE373012 T1 AT E373012T1 AT 98908948 T AT98908948 T AT 98908948T AT 98908948 T AT98908948 T AT 98908948T AT E373012 T1 ATE373012 T1 AT E373012T1
- Authority
- AT
- Austria
- Prior art keywords
- caml
- code
- nucleic acids
- receptor binding
- surface receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/810,572 US5969102A (en) | 1997-03-03 | 1997-03-03 | Lymphocyte surface receptor that binds CAML, nucleic acids encoding the same and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE373012T1 true ATE373012T1 (de) | 2007-09-15 |
Family
ID=25204137
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98908948T ATE373012T1 (de) | 1997-03-03 | 1998-03-03 | An caml bindender lymphozyteoberflächenrezeptor, nukleinsäuren die dafür kodieren und verfahren zur verwendung |
Country Status (11)
Country | Link |
---|---|
US (7) | US5969102A (de) |
EP (3) | EP1632500B1 (de) |
JP (1) | JP3594975B2 (de) |
AT (1) | ATE373012T1 (de) |
AU (1) | AU732119B2 (de) |
CA (1) | CA2284078C (de) |
DE (1) | DE69838417T2 (de) |
DK (1) | DK0964874T3 (de) |
ES (2) | ES2552095T3 (de) |
PT (1) | PT964874E (de) |
WO (1) | WO1998039361A1 (de) |
Families Citing this family (80)
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US5969102A (en) * | 1997-03-03 | 1999-10-19 | St. Jude Children's Research Hospital | Lymphocyte surface receptor that binds CAML, nucleic acids encoding the same and methods of use thereof |
WO2001060397A1 (en) | 2000-02-16 | 2001-08-23 | Genentech, Inc. | Uses of agonists and antagonists to modulate activity of tnf-related molecules |
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ATE437227T1 (de) * | 1999-01-07 | 2009-08-15 | Zymogenetics Inc | Verfahren zur therapeutischen verwendung von löslichen rezeptoren br43x2 |
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US20060067933A1 (en) * | 1999-01-07 | 2006-03-30 | Gross Jane A | Soluble receptor BR43x2 and methods of using |
US7833529B1 (en) | 1999-01-07 | 2010-11-16 | Zymogenetics, Inc. | Methods for inhibiting B lymphocyte proliferation with soluble ztnf4 receptor |
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US20030095967A1 (en) * | 1999-01-25 | 2003-05-22 | Mackay Fabienne | BAFF, inhibitors thereof and their use in the modulation of B-cell response and treatment of autoimmune disorders |
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US20030022233A1 (en) * | 1999-04-30 | 2003-01-30 | Raymond G. Goodwin | Methods of use of the taci/taci-l interaction |
EE05673B1 (et) | 1999-08-17 | 2013-08-15 | Biogen, Inc. | BAFF-retseptor (BCMA), immunoregulatoorne agens |
UA74798C2 (uk) * | 1999-10-06 | 2006-02-15 | Байоджен Айдек Ма Інк. | Спосіб лікування раку у ссавця за допомогою поліпептиду, що протидіє взаємодії april з його рецепторами |
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EP1746106A3 (de) * | 2000-04-27 | 2007-03-14 | Biogen Idec MA Inc. | Verwendung von TACI als Antitumormittel |
CA2404945C (en) * | 2000-04-27 | 2010-02-09 | Biogen, Inc. | Taci as an anti-tumor agent |
US20040013674A1 (en) * | 2001-04-27 | 2004-01-22 | Christine Ambrose | Taci as an anti-tumor agent |
MXPA02011130A (es) * | 2000-05-12 | 2003-03-10 | Amgen Inc | Metodos y composiciones de materia que se refieren a april/g70, bcma, blys/agp-3, y taci. |
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US7879328B2 (en) | 2000-06-16 | 2011-02-01 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to B lymphocyte stimulator |
NZ522700A (en) * | 2000-06-16 | 2006-02-24 | Human Genome Sciences Inc | Antibodies that immunospecifically bind to blys |
BR0112263A (pt) * | 2000-07-07 | 2003-06-24 | Eisai Co Ltd | Gene da sìntese da parede celular de fungos |
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UA83458C2 (uk) * | 2000-09-18 | 2008-07-25 | Байоджен Айдек Ма Інк. | Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf) |
AU2002215753A1 (en) * | 2000-12-07 | 2002-06-18 | The University Of British Columbia | Caml-binding peptides |
EP2301971A1 (de) * | 2001-02-20 | 2011-03-30 | ZymoGenetics, L.L.C. | Antikörper, die sowohl BCMA als auch TACI binden |
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PT2272868E (pt) * | 2003-06-05 | 2015-07-07 | Genentech Inc | Terapêutica de combinação para distúrbios de células b |
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CA2554526A1 (en) * | 2004-01-29 | 2005-08-18 | Genentech, Inc. | Variants of the extracellular domain of bcma and uses thereof |
EP1732946B1 (de) | 2004-03-08 | 2011-07-27 | ZymoGenetics, Inc. | Dimere fusionsproteine und materialien und verfahren zu deren herstellung |
WO2006052493A1 (en) * | 2004-11-04 | 2006-05-18 | Genentech, Inc. | Polypeptides that bind baff and/or april |
AU2006209237B2 (en) * | 2005-01-28 | 2010-06-24 | Biogen Ma Inc. | Use of BAFF to treat Th2-mediated conditions |
CA2618763A1 (en) * | 2005-08-09 | 2007-02-15 | Zymogenetics, Inc. | Methods for the treatment and prevention of abnormal cell proliferation using taci-fusion molecules |
EA016083B1 (ru) * | 2005-08-09 | 2012-02-28 | Займоджинетикс, Инк. | СПОСОБ ЛЕЧЕНИЯ НЕХОДЖКИНСКОЙ ЛИМФОМЫ С ПОМОЩЬЮ СЛИТОЙ МОЛЕКУЛЫ TACI-Ig |
WO2007142667A2 (en) * | 2005-10-13 | 2007-12-13 | Human Genome Sciences, Inc. | Treatment of patients with autoantibody positive disease |
US9168286B2 (en) * | 2005-10-13 | 2015-10-27 | Human Genome Sciences, Inc. | Methods and compositions for use in treatment of patients with autoantibody positive disease |
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US20100267932A1 (en) * | 2006-08-28 | 2010-10-21 | Alex Eon-Duval | Process for the purification of fc-fusion proteins |
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ATE509107T1 (de) | 2007-01-26 | 2011-05-15 | Merck Serono Sa | Aufreinigung von fc-tact-fusionsproteinen unter verwendung der ölkörper-technik |
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US9458246B2 (en) | 2013-03-13 | 2016-10-04 | Amgen Inc. | Proteins specific for BAFF and B7RP1 |
JOP20140087B1 (ar) | 2013-03-13 | 2021-08-17 | Amgen Inc | بروتينات مخصصة ل baff و b7rp1 وإستخداماتها |
US11649288B2 (en) | 2017-02-07 | 2023-05-16 | Seattle Children's Hospital | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents |
WO2018160622A1 (en) | 2017-02-28 | 2018-09-07 | Endocyte, Inc. | Compositions and methods for car t cell therapy |
US11311576B2 (en) | 2018-01-22 | 2022-04-26 | Seattle Children's Hospital | Methods of use for CAR T cells |
CN116903727A (zh) | 2020-05-08 | 2023-10-20 | 高山免疫科学股份有限公司 | 具有和不具有t细胞抑制蛋白的april和baff抑制性免疫调节蛋白及其使用方法 |
WO2022131889A1 (ko) * | 2020-12-16 | 2022-06-23 | 주식회사 굳티셀 | Taci 단백질의 용도 |
AU2022325359A1 (en) | 2021-08-10 | 2023-05-18 | Remegen Co., Ltd. | Method for treating iga nephropathy with taci-fc fusion protein |
US20240018212A1 (en) | 2021-09-30 | 2024-01-18 | RemeGen Co., Ltd | Method for treating sjogren's syndrome using taci-fc fusion protein |
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NL7807532A (nl) | 1978-07-13 | 1980-01-15 | Akzo Nv | Metaal-immunotest. |
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-
1997
- 1997-03-03 US US08/810,572 patent/US5969102A/en not_active Expired - Lifetime
-
1998
- 1998-03-03 AT AT98908948T patent/ATE373012T1/de active
- 1998-03-03 DK DK98908948T patent/DK0964874T3/da active
- 1998-03-03 EP EP05020384.3A patent/EP1632500B1/de not_active Expired - Lifetime
- 1998-03-03 JP JP53877898A patent/JP3594975B2/ja not_active Expired - Lifetime
- 1998-03-03 EP EP98908948A patent/EP0964874B1/de not_active Expired - Lifetime
- 1998-03-03 WO PCT/US1998/004270 patent/WO1998039361A1/en active IP Right Grant
- 1998-03-03 ES ES05020384.3T patent/ES2552095T3/es not_active Expired - Lifetime
- 1998-03-03 AU AU66854/98A patent/AU732119B2/en not_active Expired
- 1998-03-03 DE DE69838417T patent/DE69838417T2/de not_active Expired - Lifetime
- 1998-03-03 CA CA2284078A patent/CA2284078C/en not_active Expired - Lifetime
- 1998-03-03 PT PT98908948T patent/PT964874E/pt unknown
- 1998-03-03 ES ES98908948T patent/ES2292201T3/es not_active Expired - Lifetime
- 1998-03-03 EP EP10179571A patent/EP2292654A3/de not_active Withdrawn
-
1999
- 1999-04-12 US US09/290,333 patent/US6316222B1/en not_active Expired - Lifetime
-
2001
- 2001-02-14 US US09/782,857 patent/US6500428B1/en not_active Expired - Lifetime
-
2002
- 2002-11-12 US US10/293,816 patent/US20030082173A1/en not_active Abandoned
-
2005
- 2005-03-14 US US11/079,418 patent/US20050183148A1/en not_active Abandoned
- 2005-12-23 US US11/318,156 patent/US7355005B2/en not_active Expired - Fee Related
-
2008
- 2008-02-07 US US12/027,720 patent/US20090226473A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2292654A2 (de) | 2011-03-09 |
PT964874E (pt) | 2007-12-21 |
CA2284078A1 (en) | 1998-09-11 |
US20050183148A1 (en) | 2005-08-18 |
US20060101529A1 (en) | 2006-05-11 |
EP1632500A2 (de) | 2006-03-08 |
EP2292654A3 (de) | 2012-07-25 |
US20030082173A1 (en) | 2003-05-01 |
AU6685498A (en) | 1998-09-22 |
DE69838417T2 (de) | 2008-05-29 |
EP0964874B1 (de) | 2007-09-12 |
WO1998039361A1 (en) | 1998-09-11 |
ES2292201T3 (es) | 2008-03-01 |
DE69838417D1 (de) | 2007-10-25 |
US6500428B1 (en) | 2002-12-31 |
JP2001518080A (ja) | 2001-10-09 |
US20090226473A1 (en) | 2009-09-10 |
EP0964874A1 (de) | 1999-12-22 |
EP1632500A3 (de) | 2007-05-30 |
DK0964874T3 (da) | 2007-12-10 |
US5969102A (en) | 1999-10-19 |
AU732119B2 (en) | 2001-04-12 |
CA2284078C (en) | 2014-09-09 |
JP3594975B2 (ja) | 2004-12-02 |
ES2552095T3 (es) | 2015-11-25 |
EP1632500B1 (de) | 2015-08-05 |
US6316222B1 (en) | 2001-11-13 |
US7355005B2 (en) | 2008-04-08 |
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