ATE366323T1 - Verfahren und zusammensetzung für chromosomenspezifische färbung - Google Patents
Verfahren und zusammensetzung für chromosomenspezifische färbungInfo
- Publication number
- ATE366323T1 ATE366323T1 AT98202403T AT98202403T ATE366323T1 AT E366323 T1 ATE366323 T1 AT E366323T1 AT 98202403 T AT98202403 T AT 98202403T AT 98202403 T AT98202403 T AT 98202403T AT E366323 T1 ATE366323 T1 AT E366323T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- methods
- probes
- cytogenetic
- acid probes
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6879—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for sex determination
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/204—Modifications characterised by specific length of the oligonucleotides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/101—Temperature
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2531/00—Reactions of nucleic acids characterised by
- C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
- C12Q2531/113—PCR
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/60—Detection means characterised by use of a special device
- C12Q2565/601—Detection means characterised by use of a special device being a microscope, e.g. atomic force microscopy [AFM]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44466989A | 1989-12-01 | 1989-12-01 | |
US49709890A | 1990-03-20 | 1990-03-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE366323T1 true ATE366323T1 (de) | 2007-07-15 |
Family
ID=27034011
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT90308718T ATE176281T1 (de) | 1989-12-01 | 1990-08-08 | Verfahren und zusammensetzungen für chromosomenspezifische färbung |
AT98202403T ATE366323T1 (de) | 1989-12-01 | 1990-08-08 | Verfahren und zusammensetzung für chromosomenspezifische färbung |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT90308718T ATE176281T1 (de) | 1989-12-01 | 1990-08-08 | Verfahren und zusammensetzungen für chromosomenspezifische färbung |
Country Status (9)
Country | Link |
---|---|
EP (2) | EP0430402B2 (de) |
JP (4) | JP3771934B2 (de) |
KR (1) | KR910012263A (de) |
AT (2) | ATE176281T1 (de) |
AU (1) | AU647741B2 (de) |
DE (2) | DE69032920T4 (de) |
DK (1) | DK0885971T3 (de) |
IE (2) | IE902727A1 (de) |
NZ (1) | NZ234529A (de) |
Families Citing this family (102)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5447841A (en) | 1986-01-16 | 1995-09-05 | The Regents Of The Univ. Of California | Methods for chromosome-specific staining |
US5721098A (en) * | 1986-01-16 | 1998-02-24 | The Regents Of The University Of California | Comparative genomic hybridization |
US5756696A (en) * | 1986-01-16 | 1998-05-26 | Regents Of The University Of California | Compositions for chromosome-specific staining |
US6872817B1 (en) | 1986-01-16 | 2005-03-29 | The Regents Of The Univ. Of California | Method of staining target interphase chromosomal DNA |
US6475720B1 (en) | 1986-01-16 | 2002-11-05 | The Regents Of The University Of California | Chromosome-specific staining to detect genetic rearrangements associated with chromosome 3 and/or chromosome 17 |
US6280929B1 (en) | 1986-01-16 | 2001-08-28 | The Regents Of The University Of California | Method of detecting genetic translocations identified with chromosomal abnormalities |
US6344315B1 (en) | 1986-01-16 | 2002-02-05 | The Regents Of The University Of California | Chromosome-specific staining to detect genetic rearrangements associated with chromosome 3 and/or chromosome 17 |
US7115709B1 (en) | 1986-01-16 | 2006-10-03 | The Regents Of The University Of California | Methods of staining target chromosomal DNA employing high complexity nucleic acid probes |
ATE161960T1 (de) * | 1988-12-06 | 1998-01-15 | Flinders Technologies Pty Ltd | Isolierung von fetalen zellen aus mütterlichem blut zur ausführung von pränataler diagnostik |
US8592155B2 (en) | 1989-07-19 | 2013-11-26 | The Regents Of The University Of California | Method of detecting genetic deletions identified with chromosomal abnormalities |
AU647741B2 (en) * | 1989-12-01 | 1994-03-31 | Regents Of The University Of California, The | Methods and compositions for chromosome-specific staining |
US5789161A (en) * | 1990-09-20 | 1998-08-04 | Amoco Corporation | Methods for genome identification using direct label probe composition |
US5491224A (en) * | 1990-09-20 | 1996-02-13 | Bittner; Michael L. | Direct label transaminated DNA probe compositions for chromosome identification and methods for their manufacture |
WO1992010566A1 (en) * | 1990-12-13 | 1992-06-25 | Board Of Regents, The University Of Texas System | In-situ hybridization probes for identification and banding of specific human chromosomes and regions |
US5538869A (en) * | 1990-12-13 | 1996-07-23 | Board Of Regents, The University Of Texas System | In-situ hybridization probes for identification and banding of specific human chromosomes and regions |
US6025126A (en) | 1991-10-28 | 2000-02-15 | Arch Development Corporation | Methods and compositions for the detection of chromosomal aberrations |
GB9204610D0 (en) * | 1992-03-03 | 1992-04-15 | Lynxvale Ltd | Detection of trisomy 21;materials and methods |
US5976790A (en) | 1992-03-04 | 1999-11-02 | The Regents Of The University Of California | Comparative Genomic Hybridization (CGH) |
DE69330750T2 (de) * | 1992-03-04 | 2002-07-04 | Univ California | Vergleichende genomhybridisierung |
US7534567B2 (en) | 1992-03-04 | 2009-05-19 | The Regents Of The University Of California | Detection of nucleic acid sequence differences by comparative genomic hybridization |
EP0635067A1 (de) * | 1992-04-09 | 1995-01-25 | Ig Laboratories Inc. | Sonden zum nachweis von gemeinsamen chromosomalen aneuploiden in lebendgeborenen |
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US5830645A (en) | 1994-12-09 | 1998-11-03 | The Regents Of The University Of California | Comparative fluorescence hybridization to nucleic acid arrays |
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US5801021A (en) | 1995-10-20 | 1998-09-01 | The Regents Of The University Of California | Amplifications of chromosomal region 20q13 as a prognostic indicator in breast cancer |
US7455964B1 (en) | 1996-07-15 | 2008-11-25 | The Hospital For Sick Children | Genes from the 20q13 amplicon and their uses |
US7049424B2 (en) | 1996-07-15 | 2006-05-23 | The Regents Of The University Of California | Genes from the 20Q13 amplicon and their uses |
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JP6231709B1 (ja) * | 2016-05-31 | 2017-11-15 | シスメックス株式会社 | 蛍光画像分析装置および分析方法 |
US20230183780A1 (en) | 2016-07-25 | 2023-06-15 | InVivo BioTech Services GmbH | Dna probes for in situ hybridization on chromosomes |
WO2018057618A1 (en) | 2016-09-20 | 2018-03-29 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for identification, assessment, prevention, and treatment of aml using usp10 biomarkers and modulators |
EP3634496A4 (de) | 2017-06-06 | 2021-09-08 | Dana-Farber Cancer Institute, Inc. | Verfahren zur sensibilisierung von krebszellen gegen t-zell-vermittelte abtötung mittels modulierung von molekularen signalwegen |
JP7403965B2 (ja) * | 2019-03-29 | 2023-12-25 | シスメックス株式会社 | 蛍光画像分析装置及び蛍光画像分析方法 |
EP3962529A4 (de) | 2019-04-30 | 2023-11-01 | Dana-Farber Cancer Institute, Inc. | Verfahren zur krebsbehandlung unter verwendung von kombinationen aus anti-cx3cr1 und immuncheckpoint-blockierungsreagenzien |
MX2023010238A (es) | 2021-03-02 | 2023-12-05 | Dana Farber Cancer Inst Inc | Métodos para tratar trastornos de glóbulos rojos. |
WO2022261183A2 (en) | 2021-06-08 | 2022-12-15 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for treating and/or identifying an agent for treating intestinal cancers |
WO2023097119A2 (en) | 2021-11-29 | 2023-06-01 | Dana-Farber Cancer Institute, Inc. | Methods and compositions to modulate riok2 |
CN114240883B (zh) * | 2021-12-16 | 2022-06-07 | 易构智能科技(广州)有限公司 | 一种染色体图像处理方法及系统 |
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US4999290A (en) * | 1988-03-31 | 1991-03-12 | The Board Of Regents, The University Of Texas System | Detection of genomic abnormalities with unique aberrant gene transcripts |
US4874853A (en) * | 1988-04-18 | 1989-10-17 | City Of Hope | Synthetic oligonucleotides useful in diagnosis of chronic myelogenous leukemia |
ATE141957T1 (de) * | 1988-11-15 | 1996-09-15 | Univ Yale | In-situ-unterdrückungs-hybridisierung und verwendungen |
AU647741B2 (en) * | 1989-12-01 | 1994-03-31 | Regents Of The University Of California, The | Methods and compositions for chromosome-specific staining |
DE69330750T2 (de) * | 1992-03-04 | 2002-07-04 | Univ California | Vergleichende genomhybridisierung |
US6590076B1 (en) * | 1999-04-02 | 2003-07-08 | Corixa Corporation | Compositions for the treatment and diagnosis of breast cancer and methods for their use |
WO2000061814A1 (en) * | 1999-04-09 | 2000-10-19 | The Regents Of The University Of California | Detection of chromosome copy number changes to distinguish melanocytic nevi from malignant melanoma |
JP2006094733A (ja) * | 2004-09-28 | 2006-04-13 | As One Corp | 癌の検出方法 |
JP2008048668A (ja) * | 2006-08-24 | 2008-03-06 | Yamaguchi Univ | Dnaコピー数多型を用いた癌発症体質の判定方法 |
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- 1990-07-27 IE IE272790A patent/IE902727A1/en not_active IP Right Cessation
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- 1990-08-08 EP EP90308718A patent/EP0430402B2/de not_active Expired - Lifetime
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Also Published As
Publication number | Publication date |
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IE20070380A1 (en) | 2007-06-27 |
DE69032920T2 (de) | 1999-09-09 |
ATE176281T1 (de) | 1999-02-15 |
JP4517152B2 (ja) | 2010-08-04 |
NZ234529A (en) | 1993-12-23 |
JP2005304508A (ja) | 2005-11-04 |
KR910012263A (ko) | 1991-08-07 |
DE69032920D1 (de) | 1999-03-11 |
EP0430402B1 (de) | 1999-01-27 |
EP0430402B2 (de) | 2008-03-05 |
JPH03224499A (ja) | 1991-10-03 |
JP2003199564A (ja) | 2003-07-15 |
JP2008283989A (ja) | 2008-11-27 |
DE69032920T4 (de) | 2009-11-05 |
EP0885971A2 (de) | 1998-12-23 |
EP0885971A3 (de) | 1999-11-10 |
DE69032920T3 (de) | 2008-10-09 |
DE69034245T2 (de) | 2008-03-13 |
DE69034245D1 (de) | 2007-08-16 |
IE902727A1 (en) | 1991-06-05 |
EP0430402A3 (en) | 1991-09-11 |
EP0430402A2 (de) | 1991-06-05 |
AU647741B2 (en) | 1994-03-31 |
EP0885971B1 (de) | 2007-07-04 |
AU5898790A (en) | 1991-06-06 |
JP3771934B2 (ja) | 2006-05-10 |
DK0885971T3 (da) | 2007-11-12 |
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