ATE361061T1 - Beschichtungszusammensetzung zur geschmacksmaskierung - Google Patents

Beschichtungszusammensetzung zur geschmacksmaskierung

Info

Publication number
ATE361061T1
ATE361061T1 AT01930585T AT01930585T ATE361061T1 AT E361061 T1 ATE361061 T1 AT E361061T1 AT 01930585 T AT01930585 T AT 01930585T AT 01930585 T AT01930585 T AT 01930585T AT E361061 T1 ATE361061 T1 AT E361061T1
Authority
AT
Austria
Prior art keywords
coating composition
taste masking
masks
medicine
drug
Prior art date
Application number
AT01930585T
Other languages
English (en)
Inventor
Michael Corbo
Jatin Desai
Mahesh Patell
Ronald Warrick
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of ATE361061T1 publication Critical patent/ATE361061T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5015Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Seasonings (AREA)
  • General Preparation And Processing Of Foods (AREA)
AT01930585T 2000-04-20 2001-04-18 Beschichtungszusammensetzung zur geschmacksmaskierung ATE361061T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55792400A 2000-04-20 2000-04-20

Publications (1)

Publication Number Publication Date
ATE361061T1 true ATE361061T1 (de) 2007-05-15

Family

ID=24227421

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01930585T ATE361061T1 (de) 2000-04-20 2001-04-18 Beschichtungszusammensetzung zur geschmacksmaskierung

Country Status (9)

Country Link
US (1) US6663893B2 (de)
EP (1) EP1276470B1 (de)
AT (1) ATE361061T1 (de)
AU (1) AU2001257107A1 (de)
DE (1) DE60128215T2 (de)
DK (1) DK1276470T3 (de)
ES (1) ES2284643T3 (de)
PT (1) PT1276470E (de)
WO (1) WO2001080826A2 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US20040013737A1 (en) * 2002-07-19 2004-01-22 Philippe Becourt Taste masked oral composition of telithromycin
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US20040185119A1 (en) * 2003-02-26 2004-09-23 Theuer Richard C. Method and compositions for treating gastric hyperacidity while diminishing the likelihood of producing vitamin deficiency
US20060134054A1 (en) * 2003-12-19 2006-06-22 Council Of Scientific And Industrial Research Polymer composition for pH dependent dissolution behavior and process for preparation thereof
FR2865648B1 (fr) * 2004-02-03 2006-06-30 Philippe Perovitch Procede de diffusion de molecules insolubles en milieu aqueux et composition mettant en oeuvre ce procede
MXPA06011765A (es) 2004-04-12 2006-12-15 Pfizer Prod Inc Farmacos de sabor enmascarado en multiparticulados que se rompen.
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
NZ589750A (en) 2004-10-21 2012-07-27 Aptalis Pharmatech Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
ES2294584T3 (es) * 2005-02-18 2008-04-01 THE PROCTER & GAMBLE COMPANY Productos de confiteria que contienen cafeina.
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
FR2891147B1 (fr) * 2005-09-28 2007-12-07 Ethypharm Sa Comprimes orodispersibles de principes actifs amers
US20080138397A1 (en) * 2006-10-24 2008-06-12 Aradigm Corporation Processes for taste-masking of inhaled formulations
US10357462B2 (en) 2006-11-30 2019-07-23 Ben Research, Inc. Multiparticulates of spray-coated drug and polymer on a meltable core
US11116728B2 (en) 2006-11-30 2021-09-14 Bend Research, Inc. Multiparticulates of spray-coated drug and polymer on a meltable core
CA2956278C (en) 2008-01-04 2022-03-01 Schabar Research Associates Llc Unit oral dose compositions composed of ibuprofen and famotidine and applications thereof
ES2414856T3 (es) * 2008-12-12 2013-07-23 Paladin Labs Inc. Formulaciones de fármaco narcótico con potencial de adicción disminuido
TWI471146B (zh) 2009-12-02 2015-02-01 Aptalis Pharma Ltd 菲索特芬那定(fexofenadine)微膠囊及包含其之組合物
EP2509631A4 (de) * 2009-12-10 2014-04-02 Monosol Rx Llc Ph-empfindliche verbindungen für eine geschmacksverbergung in oral einnehmbaren dünnschichtstreifen
JP6012604B2 (ja) * 2010-09-27 2016-10-25 ビーエーエスエフ ソシエタス・ヨーロピアBasf Se 酸性有効成分のための保護コーティング
US20150118300A1 (en) 2013-10-31 2015-04-30 Cima Labs Inc. Immediate Release Abuse-Deterrent Granulated Dosage Forms
EA032013B1 (ru) * 2013-10-31 2019-03-29 Сайма Лэбс Инк. Препятствующие злоупотреблению гранулированные лекарственные формы с немедленным высвобождением
AU2015237723B2 (en) * 2014-03-26 2018-04-26 Sun Pharma Advanced Research Company Ltd. Abuse deterrent immediate release biphasic matrix solid dosage form
ES2968237T3 (es) * 2015-07-09 2024-05-08 Uniwell Laboratories Llc Composiciones farmacéuticas
CN106389339B (zh) * 2015-08-12 2020-08-04 北京科信必成医药科技发展有限公司 一种阿司匹林无水吞服掩味颗粒及其制备方法
CN105935445B (zh) * 2016-03-28 2019-02-01 赤峰赛林泰药业有限公司 含2-(-4-异丁基苯基)丙酸右旋物的药物组合物及其制备方法
WO2020225773A1 (en) 2019-05-07 2020-11-12 Clexio Biosciences Ltd. Abuse-deterrent dosage forms containing esketamine
US20220062200A1 (en) 2019-05-07 2022-03-03 Clexio Biosciences Ltd. Abuse-deterrent dosage forms containing esketamine
JP2023534810A (ja) 2020-07-15 2023-08-14 シャバー リサーチ アソシエイツ エルエルシー 急性痛の処置並びに胸やけの重症度及び/又はリスクの低減のための、イブプロフェン及びファモチジンから構成される単位経口用量組成物
CA3124579A1 (en) 2020-07-15 2022-01-15 Schabar Research Associates Llc Unit oral dose compositions composed of naproxen sodium and famotidine for the treatment of acute pain and the reduction of the severity of heartburn and/or the risk of heartburn

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3531418A (en) 1965-08-18 1970-09-29 Ncr Co En masse encapsulation process
US3453360A (en) 1966-04-27 1969-07-01 Abbott Lab Universally useful stock material for manufacturing plastic dosage units by compression tableting processes
AT270071B (de) 1966-08-12 1969-04-10 Roehm & Haas Gmbh Dragierlack für Arzneiformen
US4060598A (en) 1967-06-28 1977-11-29 Boehringer Mannheim G.M.B.H. Tablets coated with aqueous resin dispersions
US3935326A (en) 1967-06-28 1976-01-27 Boehringer Mannheim G.M.B.H. Process for coating tablets with aqueous resin dispersions
US3577512A (en) 1968-10-11 1971-05-04 Nat Patent Dev Corp Sustained release tablets
US3576760A (en) * 1969-06-13 1971-04-27 Nat Patent Dev Corp Water soluble entrapping
US3629392A (en) 1969-08-15 1971-12-21 Gilbert S Banker Entrapment compositions and processes
DE2031871C3 (de) 1970-06-27 1974-06-27 Roehm Gmbh, 6100 Darmstadt Überzugsmasse für Arzneiformen
US3821422A (en) 1971-03-04 1974-06-28 Merck & Co Inc Devil's food cake and other alkaline bakery goods
US3909444A (en) 1971-08-05 1975-09-30 Ncr Co Microcapsule
US4016254A (en) 1972-05-19 1977-04-05 Beecham Group Limited Pharmaceutical formulations
BE791458A (fr) 1972-07-31 1973-05-16 Merck & Co Inc Produit microencapsule
DE2340060A1 (de) 1973-08-08 1975-02-20 Scherer Gmbh R P Magensaftresistente gelatinekapseln und verfahren zu deren herstellung
US4112215A (en) 1975-03-20 1978-09-05 Rohm Gmbh Copolymeric resin binder powders
DE3049179A1 (de) 1975-03-20 1982-07-29 Röhm GmbH, 6100 Darmstadt Bindemittel fuer arzneimittelueberzuege.
JPS5840529B2 (ja) 1975-09-29 1983-09-06 明治製菓株式会社 ケイコウヨウセイザイノセイホウ
SE418247B (sv) 1975-11-17 1981-05-18 Haessle Ab Sett att framstella kroppar med reglerad frigoring av en aktiv komponent
CA1125698A (en) 1978-03-09 1982-06-15 Masaru Yoshida Process for preparing a polymer composition
US4330338A (en) 1978-10-02 1982-05-18 Purdue Research Foundation Pharmaceutical coating composition, and preparation and dosages so coated
DE3000979A1 (de) 1980-01-12 1981-07-23 Dr. Karl Thomae Gmbh, 7950 Biberach Neue dipyridamol-retardformen und verfahren zu ihrer herstellung
US4321253A (en) 1980-08-22 1982-03-23 Beatty Morgan L Suspension of microencapsulated bacampicillin acid addition salt for oral, especially pediatric, administration
SE8103843L (sv) 1981-06-18 1982-12-19 Astra Laekemedel Ab Farmaceutisk mixtur
US4587118A (en) 1981-07-15 1986-05-06 Key Pharmaceuticals, Inc. Dry sustained release theophylline oral formulation
IT1168014B (it) 1981-08-05 1987-05-20 Erba Farmitalia Forme farmaceutiche a cessione protratta
DE3208791A1 (de) 1982-03-11 1983-09-22 Röhm GmbH, 6100 Darmstadt Verfahren zum ueberziehen von arzneiformen mittes eines in wasser dispergierten ueberzugsmittels
US4749575A (en) 1983-10-03 1988-06-07 Bio-Dar Ltd. Microencapsulated medicament in sweet matrix
CH658188A5 (de) 1984-03-23 1986-10-31 Ciba Geigy Ag Lagerstabile schnellzerfallende pharmazeutische presslinge.
IT1214629B (it) 1985-08-29 1990-01-18 Formenti Farmaceutici Spa Procedimento di microincapsulazione di un medicamento,medicamento cosi'preparato,e composizioni farmaceutiche che lo comprendono
US4975283A (en) 1985-12-12 1990-12-04 Bristol-Myers Squibb Company Stabilized enteric coated aspirin granules and process for preparation
IT1188212B (it) 1985-12-20 1988-01-07 Paolo Colombo Sistema per il rilascio a velocita' controllata di sostanze attive
US4710384A (en) 1986-07-28 1987-12-01 Avner Rotman Sustained release tablets made from microcapsules
IT1200217B (it) 1986-09-30 1989-01-05 Valducci Roberto Membrana per uso farmaceutico ed industriale
US4760093A (en) 1986-10-21 1988-07-26 American Home Products Corporation (Del.) Spray dried acetaminophen
US4800087A (en) 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
US4968508A (en) 1987-02-27 1990-11-06 Eli Lilly And Company Sustained release matrix
KR960011236B1 (ko) 1987-05-08 1996-08-21 스미스 클라인 앤드 프렌취 라보라토리스 리미티드 제약학적 조성물 및 고체 제형
FR2618331B1 (fr) 1987-07-23 1991-10-04 Synthelabo Compositions pharmaceutiques utiles pour le traitement de l'uremie
US4851226A (en) 1987-11-16 1989-07-25 Mcneil Consumer Products Company Chewable medicament tablet containing means for taste masking
JPH0273011A (ja) 1988-07-28 1990-03-13 Warner Lambert Co 医薬投与剤型製造用のセルロースおよびアクリル系重合体の水性重合体分散体およびその投与剤型
US4916161A (en) * 1988-10-25 1990-04-10 Bristol-Myers Squibb Taste-masking pharmaceutical agents
DE3900811A1 (de) * 1989-01-13 1990-07-19 Kali Chemie Pharma Gmbh Neue arzneiform
US5084278A (en) 1989-06-02 1992-01-28 Nortec Development Associates, Inc. Taste-masked pharmaceutical compositions
EP0524180B1 (de) 1990-04-11 1995-04-26 The Upjohn Company Verfahren zum geschmacksabdecken von ibuprofen
IT1246383B (it) 1990-04-17 1994-11-18 Eurand Int Metodo per il mascheramento del sapore di farmaci
CA2068402C (en) * 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
JP3265680B2 (ja) 1992-03-12 2002-03-11 大正製薬株式会社 経口製剤用組成物
EP0667148B1 (de) 1992-11-06 2002-07-03 Hisamitsu Pharmaceutical Co., Inc. Perorale pharmazeutische zubereitung mit freisetzung im unteren verfdauungstrakt
US5260069A (en) 1992-11-27 1993-11-09 Anda Sr Pharmaceuticals Inc. Pulsatile particles drug delivery system
US5639475A (en) 1995-02-03 1997-06-17 Eurand America, Incorporated Effervescent microcapsules
US5633046A (en) 1995-05-22 1997-05-27 Xerox Corporation Multiple dip coating method
US5874418A (en) * 1997-05-05 1999-02-23 Cydex, Inc. Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use
EP1194153B1 (de) * 1999-07-09 2004-05-06 Ortho-McNeil Pharmaceutical, Inc. Geschmackskaschierte flüssige arzneizubereitungen

Also Published As

Publication number Publication date
US20020197317A1 (en) 2002-12-26
DK1276470T3 (da) 2007-06-18
ES2284643T3 (es) 2007-11-16
DE60128215T2 (de) 2008-01-10
US6663893B2 (en) 2003-12-16
EP1276470B1 (de) 2007-05-02
WO2001080826A3 (en) 2002-03-21
EP1276470A2 (de) 2003-01-22
AU2001257107A1 (en) 2001-11-07
DE60128215D1 (de) 2007-06-14
PT1276470E (pt) 2007-08-13
WO2001080826A2 (en) 2001-11-01

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