ATE339208T1 - Verwendung von progesteronrezeptorhemmern zur behandlung von steroid-resistentem brustkrebs - Google Patents

Verwendung von progesteronrezeptorhemmern zur behandlung von steroid-resistentem brustkrebs

Info

Publication number
ATE339208T1
ATE339208T1 AT01987667T AT01987667T ATE339208T1 AT E339208 T1 ATE339208 T1 AT E339208T1 AT 01987667 T AT01987667 T AT 01987667T AT 01987667 T AT01987667 T AT 01987667T AT E339208 T1 ATE339208 T1 AT E339208T1
Authority
AT
Austria
Prior art keywords
progesterone receptor
breast cancer
receptor inhibitors
resistant breast
treat steroid
Prior art date
Application number
AT01987667T
Other languages
English (en)
Inventor
Rosemarie Lichtner
Ulrike Fuhrmann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10051609A external-priority patent/DE10051609A1/de
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of ATE339208T1 publication Critical patent/ATE339208T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT01987667T 2000-10-18 2001-10-17 Verwendung von progesteronrezeptorhemmern zur behandlung von steroid-resistentem brustkrebs ATE339208T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24101000P 2000-10-18 2000-10-18
DE10051609A DE10051609A1 (de) 2000-10-18 2000-10-18 Hemmung der Wachstumsfaktorabhängigkeit von Tumorzellen

Publications (1)

Publication Number Publication Date
ATE339208T1 true ATE339208T1 (de) 2006-10-15

Family

ID=26007397

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01987667T ATE339208T1 (de) 2000-10-18 2001-10-17 Verwendung von progesteronrezeptorhemmern zur behandlung von steroid-resistentem brustkrebs

Country Status (26)

Country Link
EP (1) EP1414465B1 (de)
JP (1) JP4335525B2 (de)
KR (1) KR20030044006A (de)
CN (1) CN1311833C (de)
AT (1) ATE339208T1 (de)
AU (2) AU1595802A (de)
BG (1) BG107745A (de)
BR (1) BR0114677A (de)
CA (1) CA2423013A1 (de)
CY (1) CY1106289T1 (de)
CZ (1) CZ299945B6 (de)
DE (1) DE60123138T2 (de)
DK (1) DK1414465T3 (de)
EA (1) EA005945B1 (de)
EE (1) EE200300156A (de)
ES (1) ES2272561T3 (de)
HK (1) HK1071697A1 (de)
HR (1) HRP20030386A2 (de)
HU (1) HUP0301461A3 (de)
IL (2) IL154974A0 (de)
MX (1) MXPA03002953A (de)
NO (1) NO20031745D0 (de)
NZ (1) NZ545965A (de)
PL (1) PL366415A1 (de)
SK (1) SK4752003A3 (de)
WO (1) WO2002032429A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006054535A1 (de) * 2006-11-15 2008-05-21 Bayer Schering Pharma Aktiengesellschaft Progesteronrezeptorantagonisten
DE102009034366A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034367A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034368A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034362A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034526A1 (de) 2009-07-21 2011-02-10 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034525A1 (de) 2009-07-21 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102010007719A1 (de) * 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten
DE102010007722A1 (de) 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0466315A3 (en) * 1990-05-30 1992-07-01 Larrian Gillespie Compositions containing xylan sulphates for affecting growth factor function and for inhibiting fibroblast proliferation
US5238950A (en) * 1991-12-17 1993-08-24 Schering Corporation Inhibitors of platelet-derived growth factor
DE19706061A1 (de) * 1997-02-07 1998-08-13 Schering Ag Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette
PE20000129A1 (es) * 1997-12-23 2000-03-11 Schering Ag 11 beta-halogeno-estratrienos sustituidos en 7 alfa, asi como el procedimiento para elaborar preparados farmaceuticos que contienen tales 11 beta-halogeno-estratrienos sustituidos en 7 alfa
FR2789393B1 (fr) * 1999-02-05 2001-10-12 Centre Nat Rech Scient Lactol steroidique

Also Published As

Publication number Publication date
IL154974A0 (en) 2003-10-31
ES2272561T3 (es) 2007-05-01
AU2002215958C1 (en) 2002-04-29
HUP0301461A3 (en) 2010-01-28
NZ545965A (en) 2007-09-28
CN1311833C (zh) 2007-04-25
DE60123138D1 (de) 2006-10-26
CN1551772A (zh) 2004-12-01
CY1106289T1 (el) 2011-10-12
AU2002215958B2 (en) 2006-08-17
SK4752003A3 (en) 2003-10-07
JP4335525B2 (ja) 2009-09-30
EP1414465B1 (de) 2006-09-13
HRP20030386A2 (en) 2005-04-30
BR0114677A (pt) 2003-10-07
EE200300156A (et) 2003-08-15
PL366415A1 (en) 2005-01-24
WO2002032429A3 (en) 2004-02-19
DK1414465T3 (da) 2007-01-29
KR20030044006A (ko) 2003-06-02
NO20031745L (no) 2003-04-15
NO20031745D0 (no) 2003-04-15
WO2002032429A2 (en) 2002-04-25
AU1595802A (en) 2002-04-29
CA2423013A1 (en) 2002-04-25
BG107745A (bg) 2004-01-30
EA200300468A1 (ru) 2003-10-30
HUP0301461A2 (hu) 2003-10-28
HK1071697A1 (en) 2005-07-29
EA005945B1 (ru) 2005-08-25
IL154974A (en) 2007-05-15
DE60123138T2 (de) 2007-09-13
EP1414465A2 (de) 2004-05-06
CZ299945B6 (cs) 2008-12-29
MXPA03002953A (es) 2003-08-07
JP2004513094A (ja) 2004-04-30

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