HUP0301461A3 - Use of 17 alpha-fluoroalkyl steroids for producing pharmaceutical compositions for inhibition of the growth factor dependency of tumor cells - Google Patents

Use of 17 alpha-fluoroalkyl steroids for producing pharmaceutical compositions for inhibition of the growth factor dependency of tumor cells

Info

Publication number
HUP0301461A3
HUP0301461A3 HU0301461A HUP0301461A HUP0301461A3 HU P0301461 A3 HUP0301461 A3 HU P0301461A3 HU 0301461 A HU0301461 A HU 0301461A HU P0301461 A HUP0301461 A HU P0301461A HU P0301461 A3 HUP0301461 A3 HU P0301461A3
Authority
HU
Hungary
Prior art keywords
inhibition
alpha
pharmaceutical compositions
growth factor
tumor cells
Prior art date
Application number
HU0301461A
Other languages
English (en)
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10051609A external-priority patent/DE10051609A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of HUP0301461A2 publication Critical patent/HUP0301461A2/hu
Publication of HUP0301461A3 publication Critical patent/HUP0301461A3/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HU0301461A 2000-10-18 2001-10-17 Use of 17 alpha-fluoroalkyl steroids for producing pharmaceutical compositions for inhibition of the growth factor dependency of tumor cells HUP0301461A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24101000P 2000-10-18 2000-10-18
DE10051609A DE10051609A1 (de) 2000-10-18 2000-10-18 Hemmung der Wachstumsfaktorabhängigkeit von Tumorzellen
PCT/EP2001/012004 WO2002032429A2 (en) 2000-10-18 2001-10-17 Use of inhibitors of progesterone receptor for treating cancer

Publications (2)

Publication Number Publication Date
HUP0301461A2 HUP0301461A2 (hu) 2003-10-28
HUP0301461A3 true HUP0301461A3 (en) 2010-01-28

Family

ID=26007397

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0301461A HUP0301461A3 (en) 2000-10-18 2001-10-17 Use of 17 alpha-fluoroalkyl steroids for producing pharmaceutical compositions for inhibition of the growth factor dependency of tumor cells

Country Status (26)

Country Link
EP (1) EP1414465B1 (hu)
JP (1) JP4335525B2 (hu)
KR (1) KR20030044006A (hu)
CN (1) CN1311833C (hu)
AT (1) ATE339208T1 (hu)
AU (2) AU1595802A (hu)
BG (1) BG107745A (hu)
BR (1) BR0114677A (hu)
CA (1) CA2423013A1 (hu)
CY (1) CY1106289T1 (hu)
CZ (1) CZ299945B6 (hu)
DE (1) DE60123138T2 (hu)
DK (1) DK1414465T3 (hu)
EA (1) EA005945B1 (hu)
EE (1) EE200300156A (hu)
ES (1) ES2272561T3 (hu)
HK (1) HK1071697A1 (hu)
HR (1) HRP20030386A2 (hu)
HU (1) HUP0301461A3 (hu)
IL (2) IL154974A0 (hu)
MX (1) MXPA03002953A (hu)
NO (1) NO20031745D0 (hu)
NZ (1) NZ545965A (hu)
PL (1) PL366415A1 (hu)
SK (1) SK4752003A3 (hu)
WO (1) WO2002032429A2 (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006054535A1 (de) * 2006-11-15 2008-05-21 Bayer Schering Pharma Aktiengesellschaft Progesteronrezeptorantagonisten
DE102009034367A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034368A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034366A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034362A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034526A1 (de) 2009-07-21 2011-02-10 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034525A1 (de) 2009-07-21 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102010007719A1 (de) * 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten
DE102010007722A1 (de) 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0466315A3 (en) * 1990-05-30 1992-07-01 Larrian Gillespie Compositions containing xylan sulphates for affecting growth factor function and for inhibiting fibroblast proliferation
US5238950A (en) * 1991-12-17 1993-08-24 Schering Corporation Inhibitors of platelet-derived growth factor
DE19706061A1 (de) * 1997-02-07 1998-08-13 Schering Ag Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette
PE20000129A1 (es) * 1997-12-23 2000-03-11 Schering Ag 11 beta-halogeno-estratrienos sustituidos en 7 alfa, asi como el procedimiento para elaborar preparados farmaceuticos que contienen tales 11 beta-halogeno-estratrienos sustituidos en 7 alfa
FR2789393B1 (fr) * 1999-02-05 2001-10-12 Centre Nat Rech Scient Lactol steroidique

Also Published As

Publication number Publication date
NO20031745L (no) 2003-04-15
BG107745A (bg) 2004-01-30
CY1106289T1 (el) 2011-10-12
WO2002032429A3 (en) 2004-02-19
CA2423013A1 (en) 2002-04-25
EP1414465A2 (en) 2004-05-06
BR0114677A (pt) 2003-10-07
IL154974A0 (en) 2003-10-31
CZ299945B6 (cs) 2008-12-29
JP4335525B2 (ja) 2009-09-30
AU2002215958C1 (en) 2002-04-29
CN1311833C (zh) 2007-04-25
SK4752003A3 (en) 2003-10-07
HK1071697A1 (en) 2005-07-29
HUP0301461A2 (hu) 2003-10-28
EP1414465B1 (en) 2006-09-13
DK1414465T3 (da) 2007-01-29
ATE339208T1 (de) 2006-10-15
IL154974A (en) 2007-05-15
NO20031745D0 (no) 2003-04-15
WO2002032429A2 (en) 2002-04-25
EA200300468A1 (ru) 2003-10-30
ES2272561T3 (es) 2007-05-01
KR20030044006A (ko) 2003-06-02
HRP20030386A2 (en) 2005-04-30
PL366415A1 (en) 2005-01-24
AU2002215958B2 (en) 2006-08-17
AU1595802A (en) 2002-04-29
EE200300156A (et) 2003-08-15
NZ545965A (en) 2007-09-28
JP2004513094A (ja) 2004-04-30
DE60123138T2 (de) 2007-09-13
MXPA03002953A (es) 2003-08-07
DE60123138D1 (de) 2006-10-26
CN1551772A (zh) 2004-12-01
EA005945B1 (ru) 2005-08-25

Similar Documents

Publication Publication Date Title
HUP0101693A3 (en) Use of steroidal sapogenins and their derivatives for producing pharmaceutical compositions for the treatment of alzheimeirs disease
IL154292A0 (en) Imidazolo-5-yl-2-anilino-pyrimidines as agents for the inhibition of the cell profiliferation
HUP0103386A3 (en) Use of quinazoline derivatives for producing pharmaceutical compositions having jak 3-inhibitor effect
AU6147401A (en) Compositions and methods for the treatment of cancer
HUP0003111A3 (en) Pharmaceutical compositions containing methylsulfonylamino pyrimidin derivative and process for their preparation
AU2003200731A1 (en) Compositions and methods for the treatment of tumor
AU2003200722A1 (en) Compositions and methods for the treatment of tumor
AU2212299A (en) Compositions and methods for the treatment of tumor
AU2495200A (en) Compositions and methods for the treatment of tumor
HU9800535D0 (en) Use of pyrimidine derivatives for producing pharmaceutical compositions for preventing tumor
HU9800291D0 (en) Use of amido-pirimidine derivatives for producing pharmaceutical compositions for inhibiting decrease of glucose-metabolismus
HUP0201872A3 (en) Steroid compounds and pharmaceutical compositions of the same
KR100510795B1 (en) Compositions and Methods for the Treatment of Tumor
HUP0201187A3 (en) Use of ecteinascidin743 for producing pharmaceutical compositions suitable for treating cancer
IL155539A0 (en) Process for the preparation of latent antithrombin iii
IL141081A0 (en) Use of biogenic estrogen sulfamates for the production of pharmaceutical compositions and pharmaceutical compositions containing biogenic estrogen sulfamates
HUP0101498A3 (en) Use of dexmedetomidine for producing pharmaceutical compositions with sedative effect
HUP0301461A3 (en) Use of 17 alpha-fluoroalkyl steroids for producing pharmaceutical compositions for inhibition of the growth factor dependency of tumor cells
EP1054979A4 (en) COMPOSITIONS AND METHODS FOR SENSITIZING AND INHIBITING GROWTH OF HUMAN CANCER CELLS
IL141426A0 (en) Compositions and methods for the treatment of tumor
IL143212A0 (en) Compositions and methods for the treatment of tumor
IL133760A0 (en) Composition for the treatment of dandruff
AU2003228450A8 (en) Inhibition of tumor growth via peroxiredoxin 3
AU2026801A (en) Melanin synthesis inhibition compound and composition containing the same
HK1037520A1 (en) Composition for stimulating the synthesis of the melanic pigment and procedure to obtain it

Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees