ATE324867T1 - Verabreichung von taxanen an angiogene blutgefässe mittels kationischer liposomen - Google Patents
Verabreichung von taxanen an angiogene blutgefässe mittels kationischer liposomenInfo
- Publication number
- ATE324867T1 ATE324867T1 AT00960004T AT00960004T ATE324867T1 AT E324867 T1 ATE324867 T1 AT E324867T1 AT 00960004 T AT00960004 T AT 00960004T AT 00960004 T AT00960004 T AT 00960004T AT E324867 T1 ATE324867 T1 AT E324867T1
- Authority
- AT
- Austria
- Prior art keywords
- cationic liposomes
- taxans
- administration
- blood vessels
- angiogenic blood
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39297699A | 1999-09-09 | 1999-09-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE324867T1 true ATE324867T1 (de) | 2006-06-15 |
Family
ID=23552795
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00960004T ATE324867T1 (de) | 1999-09-09 | 2000-09-08 | Verabreichung von taxanen an angiogene blutgefässe mittels kationischer liposomen |
Country Status (21)
Country | Link |
---|---|
US (1) | US20100226970A1 (de) |
EP (1) | EP1210065B1 (de) |
JP (2) | JP4848113B2 (de) |
KR (1) | KR100591767B1 (de) |
CN (1) | CN1235567C (de) |
AT (1) | ATE324867T1 (de) |
AU (1) | AU782714B2 (de) |
BR (1) | BR0013866A (de) |
CA (1) | CA2383412C (de) |
CZ (1) | CZ2002850A3 (de) |
DE (1) | DE60027730T2 (de) |
EA (1) | EA005923B1 (de) |
EE (1) | EE200200127A (de) |
ES (1) | ES2258471T3 (de) |
HK (1) | HK1046506B (de) |
HU (1) | HUP0202669A3 (de) |
IL (2) | IL148372A0 (de) |
MX (1) | MXPA02002579A (de) |
PL (1) | PL203128B1 (de) |
WO (1) | WO2001017508A1 (de) |
ZA (1) | ZA200201555B (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004511426A (ja) * | 2000-05-03 | 2004-04-15 | ミュンヘン バイオテク アーゲー | 活性化血管部位に関連する陽イオン性の診断薬、画像化剤、および治療薬 |
CA2383259A1 (en) | 2002-04-23 | 2003-10-23 | Celator Technologies Inc. | Synergistic compositions |
JP4778679B2 (ja) * | 2001-10-03 | 2011-09-21 | セレーター ファーマシューティカルズ インコーポレイテッド | 併用薬剤を送達するための組成物 |
US7850990B2 (en) | 2001-10-03 | 2010-12-14 | Celator Pharmaceuticals, Inc. | Compositions for delivery of drug combinations |
ES2369640T3 (es) | 2002-05-24 | 2011-12-02 | Angiotech International Ag | Composiciones y métodos para revestir implantes médicos. |
EP1553924B1 (de) * | 2002-06-26 | 2010-12-08 | MediGene AG | Neues verfahren zur stabilisierung von diagnostischen und therapeutischen verbindungen in einem kationischen trägersystem |
AU2003280505B2 (en) * | 2002-06-26 | 2009-01-15 | Syncore Biotechnology Co., Ltd | Method of producing a cationic liposomal preparation comprising a lipophilic compound |
EP1374864A1 (de) * | 2002-06-26 | 2004-01-02 | Munich Biotech AG | Amphiphile, Taxane enthaltende Zusammensetzungen |
WO2004112747A2 (en) | 2003-06-24 | 2004-12-29 | Baxter International Inc. | Specific delivery of drugs to the brain |
US8986736B2 (en) | 2003-06-24 | 2015-03-24 | Baxter International Inc. | Method for delivering particulate drugs to tissues |
CA2542217C (en) * | 2003-10-15 | 2018-03-27 | Medigene Ag | Method of administering cationic liposomes comprising an active drug |
JP2007517874A (ja) * | 2004-01-16 | 2007-07-05 | バーンズ−ジューイッシュ ホスピタル | 標的化アテローム性動脈硬化症治療法 |
AU2006243337B2 (en) * | 2005-05-04 | 2011-09-29 | Syncore Biotechnology Co., Ltd | Method of administering a cationic liposomal preparation comprising paclitaxel |
CA2922029C (en) | 2006-03-22 | 2017-11-28 | Medigene Ag | A combination of a cationic liposomal preparation comprising an antimitotic agent and a non-liposomal preparation comprising an antimitotic agent |
EP2259798B1 (de) | 2008-03-05 | 2013-12-11 | Baxter International Inc. | Zusammensetzungen und verfahren zur wirkstofffreisetzung |
US10952965B2 (en) | 2009-05-15 | 2021-03-23 | Baxter International Inc. | Compositions and methods for drug delivery |
US9706903B2 (en) | 2009-06-18 | 2017-07-18 | Endochoice, Inc. | Multiple viewing elements endoscope system with modular imaging units |
DE102009032658A1 (de) * | 2009-07-09 | 2011-01-13 | Forschungszentrum Jülich GmbH | Mischung amphipathischer Moleküle und Verfahren zur Zellmembranmodifikation durch Fusion |
KR101007925B1 (ko) * | 2009-10-07 | 2011-01-14 | 건일제약 주식회사 | 경구용 지질 나노입자 및 그의 제조방법 |
ES2923929T3 (es) * | 2016-10-28 | 2022-10-03 | Servier Lab | Formulación liposomal para uso en el tratamiento del cáncer |
KR102250123B1 (ko) | 2019-11-25 | 2021-05-10 | 주식회사 현대케피코 | 무단 변속기의 제한 목표 기어비 학습 방법 |
KR102261482B1 (ko) | 2019-12-10 | 2021-06-07 | 주식회사 현대케피코 | 무단 변속기의 킥다운 시프트 직후 구동 풀리 제어 압력 보정 방법 및 장치 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4394448A (en) * | 1978-02-24 | 1983-07-19 | Szoka Jr Francis C | Method of inserting DNA into living cells |
US4897355A (en) * | 1985-01-07 | 1990-01-30 | Syntex (U.S.A.) Inc. | N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor |
US5092885A (en) * | 1987-02-12 | 1992-03-03 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Peptides with laminin activity |
US5110730A (en) * | 1987-03-31 | 1992-05-05 | The Scripps Research Institute | Human tissue factor related DNA segments |
US5328470A (en) * | 1989-03-31 | 1994-07-12 | The Regents Of The University Of Michigan | Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor |
US5192744A (en) * | 1990-01-12 | 1993-03-09 | Northwestern University | Method of inhibiting angiogenesis of tumors |
US5264618A (en) * | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
EP0470569B1 (de) * | 1990-08-08 | 1995-11-22 | Takeda Chemical Industries, Ltd. | Intravaskulär embolisierendes Mittel mit Gehalt an einem die Angiogenesis hemmenden Stoff |
US6605712B1 (en) * | 1990-12-20 | 2003-08-12 | Arch Development Corporation | Gene transcription and ionizing radiation: methods and compositions |
PT706373E (pt) * | 1992-03-23 | 2000-11-30 | Univ Georgetown | Taxol encapsulado num liposoma e um metodo |
US6096331A (en) * | 1993-02-22 | 2000-08-01 | Vivorx Pharmaceuticals, Inc. | Methods and compositions useful for administration of chemotherapeutic agents |
WO1994026254A1 (en) * | 1993-05-17 | 1994-11-24 | The Liposome Company, Inc. | Incorporation of taxol into liposomes and gels |
ATE249448T1 (de) * | 1993-06-11 | 2003-09-15 | Upjohn Co | Delta 6,7-taxol derivate antineoplastische verbindungen und diese enthaltende pharmazeutische zusammenstellungen |
EP0711158B2 (de) * | 1993-07-29 | 2008-07-23 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Verfahren zur behandlung atherosklerose oder restenose mit hilfe eines mikrotubulusstabilisators |
US5415869A (en) * | 1993-11-12 | 1995-05-16 | The Research Foundation Of State University Of New York | Taxol formulation |
US5641755A (en) * | 1994-02-04 | 1997-06-24 | Arch Development Corp. | Regulation of x-ray mediated gene expression |
US5837682A (en) * | 1996-03-08 | 1998-11-17 | The Children's Medical Center Corporation | Angiostatin fragments and method of use |
US5512294A (en) * | 1994-08-05 | 1996-04-30 | Li; King C. | Targeted polymerized liposome contrast agents |
GB9506466D0 (en) * | 1994-08-26 | 1995-05-17 | Prolifix Ltd | Cell cycle regulated repressor and dna element |
US5580899A (en) * | 1995-01-09 | 1996-12-03 | The Liposome Company, Inc. | Hydrophobic taxane derivatives |
DE19605274A1 (de) * | 1996-02-13 | 1997-08-14 | Hoechst Ag | Nukleinsäurekonstrukte für die zellzyklusregulierte Expression von Genen, derartige Konstrukte enthaltende Zellen sowie deren Verwendung zur Herstellung von Heilmitteln |
KR100561788B1 (ko) * | 1996-03-12 | 2006-09-20 | 피지-티엑스엘 컴파니,엘.피. | 수용성파클리탁셀전구약물을포함하는조성물및이러한조성물을포함하는이식가능한의료장치 |
US5935937A (en) * | 1996-06-19 | 1999-08-10 | Fox Chase Cancer Center | Compositions and methods for inducing apoptosis |
US7112338B2 (en) * | 1997-03-12 | 2006-09-26 | The Regents Of The University Of California | Cationic liposome delivery of taxanes to angiogenic blood vessels |
US5837283A (en) * | 1997-03-12 | 1998-11-17 | The Regents Of The University Of California | Cationic lipid compositions targeting angiogenic endothelial cells |
US6146659A (en) * | 1998-07-01 | 2000-11-14 | Neopharm, Inc. | Method of administering liposomal encapsulated taxane |
WO2000047235A2 (en) * | 1999-02-10 | 2000-08-17 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of stimulating angiogenesis |
ES2358416T3 (es) * | 2001-10-30 | 2011-05-10 | Novartis Ag | Formulaciones de liberación prolongada de iloperidona y polímero en forma de estrella. |
-
2000
- 2000-09-08 BR BR0013866-5A patent/BR0013866A/pt not_active Application Discontinuation
- 2000-09-08 IL IL14837200A patent/IL148372A0/xx active IP Right Grant
- 2000-09-08 EA EA200200229A patent/EA005923B1/ru not_active IP Right Cessation
- 2000-09-08 MX MXPA02002579A patent/MXPA02002579A/es active IP Right Grant
- 2000-09-08 CN CNB008141339A patent/CN1235567C/zh not_active Expired - Lifetime
- 2000-09-08 EE EEP200200127A patent/EE200200127A/xx unknown
- 2000-09-08 AU AU71229/00A patent/AU782714B2/en not_active Expired
- 2000-09-08 CZ CZ2002850A patent/CZ2002850A3/cs unknown
- 2000-09-08 KR KR1020027003179A patent/KR100591767B1/ko active IP Right Grant
- 2000-09-08 CA CA002383412A patent/CA2383412C/en not_active Expired - Lifetime
- 2000-09-08 HU HU0202669A patent/HUP0202669A3/hu unknown
- 2000-09-08 JP JP2001521299A patent/JP4848113B2/ja not_active Expired - Lifetime
- 2000-09-08 ES ES00960004T patent/ES2258471T3/es not_active Expired - Lifetime
- 2000-09-08 WO PCT/US2000/024579 patent/WO2001017508A1/en active IP Right Grant
- 2000-09-08 DE DE60027730T patent/DE60027730T2/de not_active Expired - Lifetime
- 2000-09-08 EP EP00960004A patent/EP1210065B1/de not_active Expired - Lifetime
- 2000-09-08 PL PL354721A patent/PL203128B1/pl unknown
- 2000-09-08 AT AT00960004T patent/ATE324867T1/de active
-
2002
- 2002-02-25 ZA ZA200201555A patent/ZA200201555B/en unknown
- 2002-02-25 IL IL148372A patent/IL148372A/en unknown
- 2002-11-12 HK HK02108184.7A patent/HK1046506B/zh not_active IP Right Cessation
-
2010
- 2010-02-10 US US12/658,620 patent/US20100226970A1/en not_active Abandoned
- 2010-07-09 JP JP2010156449A patent/JP2010280667A/ja active Pending
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