ATE316146T1 - Verfahren zur herstellung von pravastatin- natriumsalz mittels streptomyces flavidovirens dsm 14455 - Google Patents

Verfahren zur herstellung von pravastatin- natriumsalz mittels streptomyces flavidovirens dsm 14455

Info

Publication number
ATE316146T1
ATE316146T1 AT01976603T AT01976603T ATE316146T1 AT E316146 T1 ATE316146 T1 AT E316146T1 AT 01976603 T AT01976603 T AT 01976603T AT 01976603 T AT01976603 T AT 01976603T AT E316146 T1 ATE316146 T1 AT E316146T1
Authority
AT
Austria
Prior art keywords
sodium salt
pravastatin sodium
streptomyces flavidovirens
producing pravastatin
dsm
Prior art date
Application number
AT01976603T
Other languages
English (en)
Inventor
Ramavana Gururaja
Anuj Goel
Madhavan Sridharan
Ramakrishnan Melarkode
Madhav Kulkarni
Acharya Poornaprajna
Deepthy Sathyanathan
Sambasivam Ganesh
Shrikumar Suryanarayan
Original Assignee
Biocon Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocon Ltd filed Critical Biocon Ltd
Application granted granted Critical
Publication of ATE316146T1 publication Critical patent/ATE316146T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT01976603T 2001-09-27 2001-09-27 Verfahren zur herstellung von pravastatin- natriumsalz mittels streptomyces flavidovirens dsm 14455 ATE316146T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2001/000161 WO2003027302A1 (en) 2001-09-27 2001-09-27 Process for producing pravastatin sodium salt using streptomyces flavidovirens dsm 14455

Publications (1)

Publication Number Publication Date
ATE316146T1 true ATE316146T1 (de) 2006-02-15

Family

ID=11076380

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01976603T ATE316146T1 (de) 2001-09-27 2001-09-27 Verfahren zur herstellung von pravastatin- natriumsalz mittels streptomyces flavidovirens dsm 14455

Country Status (15)

Country Link
US (1) US7189558B2 (de)
EP (1) EP1430138B1 (de)
JP (1) JP2005503174A (de)
KR (1) KR100725559B1 (de)
AT (1) ATE316146T1 (de)
AU (1) AU2001295867A1 (de)
BR (1) BRPI0117138B1 (de)
CA (1) CA2461951C (de)
DE (1) DE60116787T2 (de)
ES (1) ES2254499T3 (de)
HU (1) HU225432B1 (de)
IL (2) IL161079A0 (de)
MX (1) MXNL04000022A (de)
SI (1) SI1430138T1 (de)
WO (1) WO2003027302A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100470078B1 (ko) * 2003-06-12 2005-02-04 씨제이 주식회사 컴팩틴을 프라바스타틴으로 전환할 수 있는 스트렙토마이세스 종(Streptomyces sp.)CJPV 975652 및 그를 이용한 프라바스타틴의 제조방법

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX7065E (es) * 1980-06-06 1987-04-10 Sankyo Co Un procedimiento microbiologico para preparar derivados de ml-236b
US5179013A (en) * 1987-02-02 1993-01-12 Sankyo Company, Limited Cytochrome P-450 enzymes
JP2642707B2 (ja) * 1987-11-20 1997-08-20 三共株式会社 抗生物質ムレイドマイシンe,fおよびその誘導体
EP0517345B1 (de) * 1987-11-20 1995-07-19 Sankyo Company Limited Zwischenprodukte der Mureidomycin-Gruppe, ihre Herstellung und Verwendung
US6043064A (en) * 1993-10-22 2000-03-28 Bristol-Myers Squibb Company Enzymatic hydroxylation process for the preparation of HMG-CoA reductase inhibitors and intermediates thereof
KR100210482B1 (ko) * 1997-04-10 1999-07-15 김종인 스트렙토마이세스엑스포리아투스(streptomycesexfoliatus)yj-118과이를이용한프라바스타틴나트륨의제조방법
EP1015600A1 (de) * 1997-08-22 2000-07-05 Dsm N.V. Fermentative herstellung von statin
KR100414334B1 (ko) * 2001-09-29 2004-01-07 코바이오텍 (주) 프라바스타틴 나트륨의 생산 방법
US6716615B2 (en) * 2002-02-27 2004-04-06 Yung Shin Pharmaceutical Ind. Co., Ltd. Strains of saccharaothrix, process for producing pravastatin using the strains and isolation process of (HMG)-CoA reductase
KR100470078B1 (ko) * 2003-06-12 2005-02-04 씨제이 주식회사 컴팩틴을 프라바스타틴으로 전환할 수 있는 스트렙토마이세스 종(Streptomyces sp.)CJPV 975652 및 그를 이용한 프라바스타틴의 제조방법

Also Published As

Publication number Publication date
US20040209335A1 (en) 2004-10-21
JP2005503174A (ja) 2005-02-03
CA2461951A1 (en) 2003-04-03
KR100725559B1 (ko) 2007-06-08
EP1430138B1 (de) 2006-01-18
IL161079A0 (en) 2004-08-31
WO2003027302A1 (en) 2003-04-03
IL161079A (en) 2009-09-22
BRPI0117138B1 (pt) 2015-08-04
MXNL04000022A (es) 2004-11-26
HUP0401918A3 (en) 2005-05-30
SI1430138T1 (sl) 2006-04-30
DE60116787D1 (de) 2006-04-06
ES2254499T3 (es) 2006-06-16
HUP0401918A2 (hu) 2004-12-28
WO2003027302A9 (en) 2003-05-15
EP1430138A1 (de) 2004-06-23
KR20040062551A (ko) 2004-07-07
DE60116787T2 (de) 2006-08-24
AU2001295867A1 (en) 2003-04-07
US7189558B2 (en) 2007-03-13
BR0117138A (pt) 2004-10-13
CA2461951C (en) 2011-08-09
HU225432B1 (hu) 2006-11-28

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