ATE305929T1 - Verfahren zur herstellung von ascorbinsäuren unter verwendung von erdalkalisilikat katalysatoren - Google Patents
Verfahren zur herstellung von ascorbinsäuren unter verwendung von erdalkalisilikat katalysatorenInfo
- Publication number
- ATE305929T1 ATE305929T1 AT02796376T AT02796376T ATE305929T1 AT E305929 T1 ATE305929 T1 AT E305929T1 AT 02796376 T AT02796376 T AT 02796376T AT 02796376 T AT02796376 T AT 02796376T AT E305929 T1 ATE305929 T1 AT E305929T1
- Authority
- AT
- Austria
- Prior art keywords
- alkaline earth
- catalysts
- keto
- casilicate
- ascorbic acids
- Prior art date
Links
- 150000000996 L-ascorbic acids Chemical class 0.000 title abstract 2
- 239000003054 catalyst Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 4
- 235000010323 ascorbic acid Nutrition 0.000 abstract 2
- 229960005070 ascorbic acid Drugs 0.000 abstract 2
- 239000006227 byproduct Substances 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- VBUYCZFBVCCYFD-NUNKFHFFSA-N 2-dehydro-L-idonic acid Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)C(=O)C(O)=O VBUYCZFBVCCYFD-NUNKFHFFSA-N 0.000 abstract 1
- VBUYCZFBVCCYFD-UHFFFAOYSA-N D-arabino-2-Hexulosonic acid Natural products OCC(O)C(O)C(O)C(=O)C(O)=O VBUYCZFBVCCYFD-UHFFFAOYSA-N 0.000 abstract 1
- 235000000069 L-ascorbic acid Nutrition 0.000 abstract 1
- 239000002211 L-ascorbic acid Substances 0.000 abstract 1
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 239000011668 ascorbic acid Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000006386 neutralization reaction Methods 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000011877 solvent mixture Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 238000010626 work up procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/62—Three oxygen atoms, e.g. ascorbic acid
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31486001P | 2001-08-24 | 2001-08-24 | |
| US32228101P | 2001-09-14 | 2001-09-14 | |
| PCT/US2002/025280 WO2003018569A1 (en) | 2001-08-24 | 2002-08-09 | Process for ascorbic acids using alkaline earth silicate catalysts |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE305929T1 true ATE305929T1 (de) | 2005-10-15 |
Family
ID=26979597
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02796376T ATE305929T1 (de) | 2001-08-24 | 2002-08-09 | Verfahren zur herstellung von ascorbinsäuren unter verwendung von erdalkalisilikat katalysatoren |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6740762B2 (de) |
| EP (1) | EP1419147B1 (de) |
| JP (1) | JP2005506978A (de) |
| CN (1) | CN1269809C (de) |
| AT (1) | ATE305929T1 (de) |
| DE (1) | DE60206511T2 (de) |
| WO (1) | WO2003018569A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6476239B1 (en) * | 2002-02-12 | 2002-11-05 | Eastman Chemical Company | Process for the preparation of ascorbic acid |
| US8071959B2 (en) * | 2005-12-21 | 2011-12-06 | Ottawa Heart Institute Research Corp. | Rubidium generator for cardiac perfusion imaging and method of making and maintaining same |
| US20080299624A1 (en) * | 2007-06-01 | 2008-12-04 | Edward Heslop | Continuous fermentation apparatus and method |
| EA019977B1 (ru) * | 2008-06-25 | 2014-07-30 | Тотал Петрокемикалз Ресерч Фелюи | Способ получения олефинов из органических веществ |
| WO2009156435A2 (en) * | 2008-06-25 | 2009-12-30 | Total Petrochemicals Research Feluy | Process to make olefins and aromatics from organics |
| US8957271B2 (en) * | 2008-06-25 | 2015-02-17 | Total Research & Technology Feluy | Process to make olefins from oxygenates |
| US8957272B2 (en) * | 2008-06-25 | 2015-02-17 | Total Research & Technology Feluy | Process to make olefins from oxygenates |
| TWI630170B (zh) * | 2016-12-16 | 2018-07-21 | 帆宣系統科技股份有限公司 | 高濃度過氧化氫水溶液之處理方法 |
| CN110372649A (zh) * | 2019-08-08 | 2019-10-25 | 安徽丰原发酵技术工程研究有限公司 | 一种以古龙酸为原料的一步酸法制备维生素c的方法 |
| CN110590868B (zh) * | 2019-09-17 | 2023-02-17 | 石药集团维生药业（石家庄）有限公司 | 一种2-酮基-l-古龙酸甲酯生产工艺 |
| CN114369075B (zh) * | 2022-02-14 | 2023-09-29 | 河北乐开节能科技股份有限公司 | 利用2-酮基-l-古龙酸的水溶液一步制备vc结晶的方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB428814A (en) | 1933-10-25 | 1935-05-20 | Tadeus Reichstein | Process for the manufacture of laevo-ascorbic acid (vitamin-c) |
| US2265121A (en) | 1933-10-25 | 1941-12-02 | Hoffmann La Roche | Process for the manufacture of levoascorbic acid |
| GB428815A (en) | 1933-12-09 | 1935-05-20 | Tadeus Reichstein | Process for the manufacture of laevo-ascorbic acid (vitamin-c) |
| US2491065A (en) | 1941-12-01 | 1949-12-13 | Tno | Process for producing ascorbic acid from 2-keto-levo-gulonic acid or its derivatives |
| US2462251A (en) | 1945-05-16 | 1949-02-22 | Merck & Co Inc | Process for preparing ascorbic acids |
| US2590163A (en) * | 1948-05-13 | 1952-03-25 | Spolek | Production of an acid of the ascorbic acid type from a 2-keto-hexonic acid |
| GB945538A (en) * | 1961-04-28 | 1964-01-02 | Takeda Chemical Industries Ltd | A method for preparing ascorbic acid or its related compounds |
| CH490368A (fr) | 1968-02-01 | 1970-05-15 | Politechnika Slaska Im Wincent | Procédé de production de vitamine C |
| DD141832A1 (de) | 1978-10-31 | 1980-05-21 | Joachim Schmidt | Verfahren und vorrichtung zur herstellung von l-ascorbinsaeure |
| DE3621781A1 (de) | 1985-07-05 | 1987-01-15 | Takeda Chemical Industries Ltd | Verfahren zur reinigung von l-ascorbinsaeure |
| CN86105960A (zh) | 1985-08-09 | 1987-05-13 | 鲁布里佐尔公司 | 在基本无水条件下从2-酮-l-古洛糖酸制备l-抗坏血酸 |
| DE3819045C2 (de) * | 1987-06-08 | 1997-06-19 | Takeda Chemical Industries Ltd | Herstellung von L-Ascorbinsäure |
| EP0324261A1 (de) * | 1988-01-06 | 1989-07-19 | Pfizer Inc. | Herstellung von Ascorbinsäure aus 2-Keto-L-gulonsäure unter im wesentlichen wasserfreien Bedingungen in Gegenwart eines sauren Katalysators und eines lipophilen grenzflächenaktiven Mittels mit einer niedrigen hydrophilen:lipophilen Gleichgewichtswert |
| DE3843389A1 (de) | 1988-12-23 | 1990-06-28 | Basf Ag | Verfahren zur herstellung von ascorbinsaeure |
| FR2648136B1 (fr) | 1989-06-12 | 1994-06-17 | Rhone Poulenc Sante | Procede de preparation de l'acide ascorbique |
| CH678057A5 (de) | 1989-06-26 | 1991-07-31 | Enco Eng Ag | Verfahren zur herstellung von natrium- oder kalium-l-ascorbat. |
| JP3134236B2 (ja) | 1992-01-30 | 2001-02-13 | 株式会社林原生物化学研究所 | α−グリコシル−Ｌ−アスコルビン酸高含有物の製造方法とその製造のための分離システム |
| JPH08176133A (ja) | 1994-12-26 | 1996-07-09 | Takeda Chem Ind Ltd | Ｌ−アスコルビン酸の精製法 |
| IL115564A (en) | 1995-10-11 | 1999-06-20 | Yissum Res Dev Co | Process for the recovery of ascorbic acid from an aqueous feed solution |
| DE19547073C1 (de) | 1995-12-16 | 1996-11-14 | Merck Patent Gmbh | Verfahren zur Herstellung von Ascorbinsäure |
| DE19734086C1 (de) | 1997-08-07 | 1998-08-13 | Merck Patent Gmbh | Verfahren zur Herstellung von L-Ascorbinsäure |
| DE19904821C1 (de) | 1999-02-05 | 2000-07-06 | Merck Patent Gmbh | Verfahren zur Herstellung von L-Ascobinsäure |
-
2002
- 2002-08-07 US US10/213,736 patent/US6740762B2/en not_active Expired - Fee Related
- 2002-08-09 EP EP02796376A patent/EP1419147B1/de not_active Expired - Lifetime
- 2002-08-09 CN CNB028165934A patent/CN1269809C/zh not_active Expired - Fee Related
- 2002-08-09 AT AT02796376T patent/ATE305929T1/de not_active IP Right Cessation
- 2002-08-09 WO PCT/US2002/025280 patent/WO2003018569A1/en not_active Ceased
- 2002-08-09 JP JP2003523232A patent/JP2005506978A/ja active Pending
- 2002-08-09 DE DE60206511T patent/DE60206511T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1419147A1 (de) | 2004-05-19 |
| DE60206511T2 (de) | 2006-05-18 |
| JP2005506978A (ja) | 2005-03-10 |
| US6740762B2 (en) | 2004-05-25 |
| DE60206511D1 (de) | 2005-11-10 |
| WO2003018569A1 (en) | 2003-03-06 |
| CN1269809C (zh) | 2006-08-16 |
| US20030073854A1 (en) | 2003-04-17 |
| CN1547576A (zh) | 2004-11-17 |
| EP1419147B1 (de) | 2005-10-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |