ATE304842T1 - Arzneizusammensetzungen enthaltend rapamycinderivate - Google Patents
Arzneizusammensetzungen enthaltend rapamycinderivateInfo
- Publication number
- ATE304842T1 ATE304842T1 AT02022256T AT02022256T ATE304842T1 AT E304842 T1 ATE304842 T1 AT E304842T1 AT 02022256 T AT02022256 T AT 02022256T AT 02022256 T AT02022256 T AT 02022256T AT E304842 T1 ATE304842 T1 AT E304842T1
- Authority
- AT
- Austria
- Prior art keywords
- compositions containing
- phosphatidylglycerol
- medicinal compositions
- sub
- salt
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9601120.0A GB9601120D0 (en) | 1996-01-19 | 1996-01-19 | Organic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE304842T1 true ATE304842T1 (de) | 2005-10-15 |
Family
ID=10787276
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05018663T ATE510532T1 (de) | 1996-01-19 | 1997-01-20 | Arzneizusammensetzungen enthaltend rapamycinderivate |
AT02022256T ATE304842T1 (de) | 1996-01-19 | 1997-01-20 | Arzneizusammensetzungen enthaltend rapamycinderivate |
AT02022257T ATE310504T1 (de) | 1996-01-19 | 1997-01-20 | Arzneizusammensetzungen enthaltend ascomycinderivate |
AT97901563T ATE239449T1 (de) | 1996-01-19 | 1997-01-20 | (3'-desoxy-3-oxo-mebmt)1-(val)2-ciclosporin enthaltende arzneimittelemulsion |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05018663T ATE510532T1 (de) | 1996-01-19 | 1997-01-20 | Arzneizusammensetzungen enthaltend rapamycinderivate |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02022257T ATE310504T1 (de) | 1996-01-19 | 1997-01-20 | Arzneizusammensetzungen enthaltend ascomycinderivate |
AT97901563T ATE239449T1 (de) | 1996-01-19 | 1997-01-20 | (3'-desoxy-3-oxo-mebmt)1-(val)2-ciclosporin enthaltende arzneimittelemulsion |
Country Status (14)
Country | Link |
---|---|
US (2) | USRE42014E1 (de) |
EP (4) | EP1679064B1 (de) |
JP (2) | JP4077386B2 (de) |
KR (1) | KR100485146B1 (de) |
AT (4) | ATE510532T1 (de) |
AU (1) | AU1543497A (de) |
CA (2) | CA2678707A1 (de) |
DE (3) | DE69734253T2 (de) |
DK (4) | DK1273288T3 (de) |
ES (4) | ES2199338T3 (de) |
GB (1) | GB9601120D0 (de) |
HK (3) | HK1054183B (de) |
PT (2) | PT1679064E (de) |
WO (1) | WO1997025977A1 (de) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
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US5660858A (en) * | 1996-04-03 | 1997-08-26 | Research Triangle Pharmaceuticals | Cyclosporin emulsions |
ATE340586T1 (de) * | 1996-07-30 | 2006-10-15 | Novartis Pharma Gmbh | Pharmazeutische zusammensetzungen zur behandlung der transplantatabstossung sowie der autoimmun- oder entzündlichen zustände |
US20030199425A1 (en) * | 1997-06-27 | 2003-10-23 | Desai Neil P. | Compositions and methods for treatment of hyperplasia |
KR100587551B1 (ko) | 1997-12-10 | 2006-06-08 | 싸이클로스포린 테라퓨틱스 리미티드 | 오메가-3 지방산 오일을 함유하는 약학 조성물 |
DE19810655A1 (de) * | 1998-03-12 | 1999-09-16 | Univ Eberhard Karls | Arzneimittel mit einem Gehalt an Ciclosporin |
TW537894B (en) | 1998-05-26 | 2003-06-21 | Novartis Ag | A spontaneously dispersible pharmaceutical composition comprising a piperidine substance P antagonist |
US6376517B1 (en) * | 1998-08-14 | 2002-04-23 | Gpi Nil Holdings, Inc. | Pipecolic acid derivatives for vision and memory disorders |
US7265150B1 (en) * | 1998-08-14 | 2007-09-04 | Gpi Nil Holdings Inc. | Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds for vision and memory disorders |
MXPA01010988A (es) * | 1999-04-30 | 2004-04-21 | Sucampo Ag | Uso de un compuesto macrolido para el tratamiento del ojo seco. |
US7063857B1 (en) | 1999-04-30 | 2006-06-20 | Sucampo Ag | Use of macrolide compounds for the treatment of dry eye |
AU4565000A (en) | 1999-05-10 | 2000-11-21 | Novartis Ag | Organic compounds |
US6720001B2 (en) * | 1999-10-18 | 2004-04-13 | Lipocine, Inc. | Emulsion compositions for polyfunctional active ingredients |
AU1074902A (en) | 2000-10-31 | 2002-05-15 | Pharma Mar Sa | Kahalalide f |
PT3351246T (pt) | 2001-02-19 | 2019-06-07 | Novartis Pharma Ag | Derivado de rapamicina para o tratamento de um tumor sólido associado a angiogenese desregulada |
AU2002320407A1 (en) * | 2001-07-10 | 2003-01-29 | Trustees Of Boston University | Modified-fat nutritional products useful for preventing or treating obesity |
US6641611B2 (en) | 2001-11-26 | 2003-11-04 | Swaminathan Jayaraman | Therapeutic coating for an intravascular implant |
US20040137066A1 (en) * | 2001-11-26 | 2004-07-15 | Swaminathan Jayaraman | Rationally designed therapeutic intravascular implant coating |
ES2326040T3 (es) | 2001-10-19 | 2009-09-29 | Isotechnika Inc. | Sintesis de analogos de ciclosporina. |
KR20050086648A (ko) * | 2002-11-15 | 2005-08-30 | 노파르티스 아게 | 약물 전달 시스템 |
GB0307866D0 (en) * | 2003-04-04 | 2003-05-14 | Novartis Ag | Pharmaceutical composition |
GB0307867D0 (en) * | 2003-04-04 | 2003-05-14 | Novartis Ag | Pharmaceutical composition |
AU2004274026A1 (en) * | 2003-09-18 | 2005-03-31 | Macusight, Inc. | Transscleral delivery |
WO2006135415A2 (en) * | 2004-09-08 | 2006-12-21 | University Of Florida Research Foundation, Inc. | Micelles and nanoemulsions for preventative and reactive treatment of atherosclerosis |
GB0428151D0 (en) | 2004-12-22 | 2005-01-26 | Novartis Ag | Organic compounds |
KR101387456B1 (ko) | 2005-02-09 | 2014-04-21 | 산텐 세이야꾸 가부시키가이샤 | 질환 또는 상태의 치료를 위한 액체 제제 |
US8663639B2 (en) * | 2005-02-09 | 2014-03-04 | Santen Pharmaceutical Co., Ltd. | Formulations for treating ocular diseases and conditions |
EP2001438A2 (de) | 2006-02-09 | 2008-12-17 | Macusight, Inc. | Stabile formulierungen sowie verfahren zu ihrer herstellung und verwendung |
DK2001466T3 (en) | 2006-03-23 | 2016-02-29 | Santen Pharmaceutical Co Ltd | LOW-DOSAGE RAPAMYCINE FOR TREATMENT OF VASCULAR PERMEABILITY-RELATED DISEASES |
US7883855B2 (en) | 2006-07-21 | 2011-02-08 | Abbott Laboratories | Immunosuppressant drug extraction reagent for immunoassays |
US20080175887A1 (en) * | 2006-11-20 | 2008-07-24 | Lixiao Wang | Treatment of Asthma and Chronic Obstructive Pulmonary Disease With Anti-proliferate and Anti-inflammatory Drugs |
EP2066321A2 (de) * | 2006-11-20 | 2009-06-10 | Lutonix, Inc. | Behandlung von asthma und chronisch obstruktiver lungenerkrankung mit antiproliferativen und entzündungshemmenden mitteln |
CA2673296C (en) * | 2006-12-29 | 2012-10-16 | Abbott Laboratories | Improved assay for immunosuppressant drugs |
US7914999B2 (en) * | 2006-12-29 | 2011-03-29 | Abbott Laboratories | Non-denaturing lysis reagent |
WO2008082984A2 (en) | 2006-12-29 | 2008-07-10 | Abbott Laboratories | Non-denaturing lysis reagent for use with capture-in-solution immunoassay |
WO2008082979A2 (en) | 2006-12-29 | 2008-07-10 | Abbott Laboratories | Diagnostic test for the detection of a molecule or drug in whole blood |
FR2911069B1 (fr) * | 2007-01-09 | 2009-04-03 | Physica Pharma Soc Par Actions | Composition pharmaceutique parenterale et son procede de preparation |
US20080265343A1 (en) * | 2007-04-26 | 2008-10-30 | International Business Machines Corporation | Field effect transistor with inverted t shaped gate electrode and methods for fabrication thereof |
ES2567455T3 (es) * | 2008-10-10 | 2016-04-22 | Dara Biosciences, Inc. | Nanoemulsiones que comprenden derivados de espicamicina para su uso en el tratamiento del dolor |
EP2682106A1 (de) | 2012-07-03 | 2014-01-08 | Phares Pharmaceutical Research N.V. | Verfahren zum Auflösen biologisch aktiver Verbindungen |
US10172789B2 (en) | 2013-01-24 | 2019-01-08 | Palvella Therapeutics Llc | Compositions for transdermal delivery of mTOR inhibitors |
HUP1400075A2 (hu) | 2014-02-14 | 2015-08-28 | Druggability Technologies Ip Holdco Jersey Ltd | Sirolimus és származékainak komplexei, elõállítása és gyógyszerészeti kompozíciói |
HUE059448T2 (hu) | 2016-10-28 | 2022-11-28 | Servier Lab | Liposzómás készítmény, rák kezelésében való alkalmazásra |
EP3565520A4 (de) | 2017-01-06 | 2020-08-19 | Palvella Therapeutics, Inc. | Wasserfreie zusammensetzungen von mtor-hemmern und verfahren zur verwendung |
US11000513B2 (en) | 2018-07-02 | 2021-05-11 | Palvella Therapeutics, Inc. | Anhydrous compositions of mTOR inhibitors and methods of use |
KR102003183B1 (ko) | 2019-02-27 | 2019-07-24 | 배영진 | 안면마스크 |
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DE296122C (de) * | ||||
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1996
- 1996-01-19 GB GBGB9601120.0A patent/GB9601120D0/en active Pending
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1997
- 1997-01-20 EP EP05018663A patent/EP1679064B1/de not_active Expired - Lifetime
- 1997-01-20 PT PT05018663T patent/PT1679064E/pt unknown
- 1997-01-20 DK DK02022256T patent/DK1273288T3/da active
- 1997-01-20 WO PCT/EP1997/000252 patent/WO1997025977A1/en active IP Right Grant
- 1997-01-20 DE DE69734253T patent/DE69734253T2/de not_active Expired - Lifetime
- 1997-01-20 CA CA002678707A patent/CA2678707A1/en not_active Abandoned
- 1997-01-20 DE DE69734742T patent/DE69734742T2/de not_active Expired - Lifetime
- 1997-01-20 ES ES97901563T patent/ES2199338T3/es not_active Expired - Lifetime
- 1997-01-20 DE DE69721729T patent/DE69721729T2/de not_active Expired - Lifetime
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- 1997-01-20 AT AT05018663T patent/ATE510532T1/de active
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- 1997-01-20 CA CA2240339A patent/CA2240339C/en not_active Expired - Lifetime
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- 1997-01-20 EP EP02022256A patent/EP1273288B1/de not_active Expired - Lifetime
- 1997-01-20 DK DK97901563T patent/DK0874621T3/da active
- 1997-01-20 ES ES02022257T patent/ES2253483T3/es not_active Expired - Lifetime
- 1997-01-20 AT AT02022257T patent/ATE310504T1/de active
- 1997-01-20 AU AU15434/97A patent/AU1543497A/en not_active Abandoned
- 1997-01-20 EP EP97901563A patent/EP0874621B1/de not_active Expired - Lifetime
- 1997-01-20 AT AT97901563T patent/ATE239449T1/de active
- 1997-01-20 US US10/345,665 patent/USRE42014E1/en not_active Expired - Lifetime
- 1997-01-20 US US09/091,072 patent/US6239102B1/en not_active Ceased
- 1997-01-20 KR KR10-1998-0704696A patent/KR100485146B1/ko not_active IP Right Cessation
- 1997-01-20 DK DK02022257T patent/DK1273289T3/da active
- 1997-01-20 PT PT97901563T patent/PT874621E/pt unknown
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- 1997-01-20 ES ES02022256T patent/ES2247245T3/es not_active Expired - Lifetime
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1999
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