ATE304354T1 - Kaliumkanal-modulierende imidazolderivate - Google Patents
Kaliumkanal-modulierende imidazolderivateInfo
- Publication number
- ATE304354T1 ATE304354T1 AT02745529T AT02745529T ATE304354T1 AT E304354 T1 ATE304354 T1 AT E304354T1 AT 02745529 T AT02745529 T AT 02745529T AT 02745529 T AT02745529 T AT 02745529T AT E304354 T1 ATE304354 T1 AT E304354T1
- Authority
- AT
- Austria
- Prior art keywords
- potassium channel
- imidazole derivatives
- channel modulating
- disorders
- neurodegenerating
- Prior art date
Links
- RAXXELZNTBOGNW-UHFFFAOYSA-N 1H-imidazole Chemical class C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 title 1
- 102000004257 Potassium Channel Human genes 0.000 title 1
- 229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 title 1
- 108020001213 potassium channel Proteins 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000020925 Bipolar disease Diseases 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000002551 irritable bowel syndrome Diseases 0.000 abstract 1
- 230000033764 rhythmic process Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Networks Using Active Elements (AREA)
- Detergent Compositions (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Control Of Transmission Device (AREA)
- Molds, Cores, And Manufacturing Methods Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0107820A FR2825926A1 (fr) | 2001-06-14 | 2001-06-14 | Derives d'imidazoles modulant les canaux sodiques |
| PCT/FR2002/002039 WO2002102375A2 (fr) | 2001-06-14 | 2002-06-14 | Derives d'imidazoles modulant les canaux sodiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE304354T1 true ATE304354T1 (de) | 2005-09-15 |
Family
ID=8864329
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02745529T ATE304354T1 (de) | 2001-06-14 | 2002-06-14 | Kaliumkanal-modulierende imidazolderivate |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US7157483B2 (de) |
| EP (1) | EP1401432B1 (de) |
| JP (1) | JP2005500297A (de) |
| KR (1) | KR20040030672A (de) |
| CN (1) | CN1535148A (de) |
| AT (1) | ATE304354T1 (de) |
| BR (1) | BR0210285A (de) |
| CA (1) | CA2449916A1 (de) |
| CZ (1) | CZ297321B6 (de) |
| DE (1) | DE60206171T2 (de) |
| DK (1) | DK1401432T3 (de) |
| ES (1) | ES2249595T3 (de) |
| FR (1) | FR2825926A1 (de) |
| HU (1) | HUP0400195A3 (de) |
| IS (1) | IS2367B (de) |
| MX (1) | MXPA03011508A (de) |
| NO (1) | NO20035553D0 (de) |
| NZ (1) | NZ529741A (de) |
| PL (1) | PL366722A1 (de) |
| RU (1) | RU2296565C2 (de) |
| WO (1) | WO2002102375A2 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1747936A (zh) * | 2003-02-12 | 2006-03-15 | 特兰斯泰克制药公司 | 作为治疗试剂的取代吡咯衍生物 |
| ZA200507752B (en) * | 2003-03-28 | 2007-01-31 | Threshold Pharmaceuticals Inc | Compositions and methods for treating cancer |
| US7829552B2 (en) * | 2003-11-19 | 2010-11-09 | Metabasis Therapeutics, Inc. | Phosphorus-containing thyromimetics |
| JP2008542301A (ja) | 2005-05-26 | 2008-11-27 | メタバシス・セラピューティクス・インコーポレイテッド | 脂肪性肝疾患の処置のための甲状腺ホルモン様薬剤 |
| CN102746336B (zh) | 2005-06-29 | 2015-08-19 | 施瑞修德制药公司 | 氨基磷酸酯烷化剂前体药物 |
| CA2632653C (en) * | 2005-12-07 | 2014-11-04 | Ramot At Tel Aviv University Ltd. | Chemical derivatives of jasmonate, pharmaceutical compositions and methods of use thereof in the treatment of cancer |
| US9284274B2 (en) | 2005-12-07 | 2016-03-15 | Ramot At Tel-Aviv University Ltd. | Chemical derivatives of jasmonate, pharmaceutical compositions and methods of use thereof |
| WO2007066337A2 (en) * | 2005-12-07 | 2007-06-14 | Sepal Pharma Ltd. | Jasmonate derivatives, pharmaceutical compositions and methods of use thereof |
| EP2114157B1 (de) | 2006-12-26 | 2021-05-26 | ImmunoGenesis, Inc. | Phosphoramidatalkylator-prodrug für die krebstherapie |
| US7883898B2 (en) * | 2007-05-07 | 2011-02-08 | General Electric Company | Method and apparatus for measuring pH of low alkalinity solutions |
| US8188080B2 (en) * | 2007-10-17 | 2012-05-29 | Sanford-Burnham Medical Research Institute | VHR protein tyrosine phosphatase inhibitors, compositions and methods of use |
| US8232290B2 (en) * | 2008-03-25 | 2012-07-31 | Affectis Pharmaceuticals Ag | P2X7R antagonists and their use |
| US8815892B2 (en) | 2008-03-25 | 2014-08-26 | Affectis Pharmaceuticals Ag | P2X7R antagonists and their use |
| CN102171382B (zh) * | 2008-10-06 | 2013-08-14 | 四国化成工业株式会社 | 2-苄基-4-(2，4-二氯苯基)-5-甲基咪唑化合物 |
| US9284252B2 (en) | 2009-06-09 | 2016-03-15 | Sepal Pharma Ltd. | Use of jasmonate ester derivatives for treating benign hyperproliferative skin disorders |
| JP5368244B2 (ja) * | 2009-10-14 | 2013-12-18 | 四国化成工業株式会社 | ２−（２，４−ジクロロベンジル）−４−アリール−５−メチルイミダゾール化合物 |
| JP5368263B2 (ja) * | 2009-11-04 | 2013-12-18 | 四国化成工業株式会社 | ４−（２，４−ジクロロフェニル）−５−メチルイミダゾール化合物 |
| JP5368271B2 (ja) * | 2009-11-20 | 2013-12-18 | 四国化成工業株式会社 | ４−（４−ビフェニリル）−２−（２，４−ジクロロベンジル）イミダゾールおよび表面処理液 |
| EP3541395A4 (de) | 2016-11-21 | 2020-07-01 | Viking Therapeutics, Inc. | Verfahren zur behandlung einer glykogenspeicherkrankheit |
| EP3634426A4 (de) | 2017-06-05 | 2021-04-07 | Viking Therapeutics, Inc. | Zusammensetzungen zur behandlung von fibrose |
| CA3094167A1 (en) | 2018-03-22 | 2019-09-26 | Viking Therapeutics, Inc. | Crystalline forms and methods of producing crystalline forms of a compound |
| WO2020117962A1 (en) | 2018-12-05 | 2020-06-11 | Viking Therapeutics, Inc. | Compositions for the treatment of fibrosis and inflammation |
| KR20250099373A (ko) * | 2022-10-31 | 2025-07-01 | 젠엡 인코포레이티드 | 이미다졸 화합물 및 나트륨 채널 억제제로서 이의 용도 |
| WO2025231324A1 (en) * | 2024-05-02 | 2025-11-06 | Genep Inc. | Imidazole compounds and their use as sodium channel inhibitors |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1046248A (en) * | 1962-08-02 | 1966-10-19 | Benger Lab Ltd | Substituted imidazoles |
| AU518569B2 (en) * | 1979-08-07 | 1981-10-08 | Farmos-Yhtyma Oy | 4-benzyl- and 4-benzoyl imidazole derivatives |
| KR100387157B1 (ko) * | 1994-09-26 | 2003-09-29 | 시오노기세이야쿠가부시키가이샤 | 이미다졸유도체 |
| PT1036065E (pt) * | 1997-12-04 | 2004-09-30 | Allergan Inc | Derivados de imidazol substituidos com actividade do tipo agonista nos receptores alfa 2b ou 2b/2c adrenergicos |
| US6003118A (en) * | 1997-12-16 | 1999-12-14 | Acer Laboratories Inc. | Method and apparatus for synchronizing clock distribution of a data processing system |
| UA72244C2 (en) * | 1999-03-26 | 2005-02-15 | Aryl-substituted pyrazols, imidazols, oxazols, thiazols, pyrrols and their use | |
| AR024077A1 (es) * | 1999-05-25 | 2002-09-04 | Smithkline Beecham Corp | Compuestos antibacterianos |
| TWI292316B (en) * | 1999-10-11 | 2008-01-11 | Sod Conseils Rech Applic | Pharmaceutical composition of thiazole derivatives intended to inhibit mao and/or lipidic peroxidation and/or to act as modulators of sodium channels and the use thereof |
| AR032292A1 (es) * | 1999-12-16 | 2003-11-05 | Schering Corp | Imidazoles sustituidos, composiciones farmaceuticas y el uso de dichos imidazoles para la manufactura de un medicamento para los tratamientos de desordenes en la alimentacion |
-
2001
- 2001-06-14 FR FR0107820A patent/FR2825926A1/fr not_active Withdrawn
-
2002
- 2002-06-14 DK DK02745529T patent/DK1401432T3/da active
- 2002-06-14 NZ NZ529741A patent/NZ529741A/en unknown
- 2002-06-14 CZ CZ20033550A patent/CZ297321B6/cs not_active IP Right Cessation
- 2002-06-14 MX MXPA03011508A patent/MXPA03011508A/es active IP Right Grant
- 2002-06-14 ES ES02745529T patent/ES2249595T3/es not_active Expired - Lifetime
- 2002-06-14 US US10/480,977 patent/US7157483B2/en not_active Expired - Fee Related
- 2002-06-14 CA CA002449916A patent/CA2449916A1/fr not_active Abandoned
- 2002-06-14 CN CNA028111842A patent/CN1535148A/zh active Pending
- 2002-06-14 KR KR10-2003-7016257A patent/KR20040030672A/ko not_active Abandoned
- 2002-06-14 BR BR0210285-4A patent/BR0210285A/pt not_active IP Right Cessation
- 2002-06-14 PL PL02366722A patent/PL366722A1/xx not_active Application Discontinuation
- 2002-06-14 DE DE60206171T patent/DE60206171T2/de not_active Expired - Fee Related
- 2002-06-14 WO PCT/FR2002/002039 patent/WO2002102375A2/fr not_active Ceased
- 2002-06-14 EP EP02745529A patent/EP1401432B1/de not_active Expired - Lifetime
- 2002-06-14 HU HU0400195A patent/HUP0400195A3/hu unknown
- 2002-06-14 JP JP2003504962A patent/JP2005500297A/ja active Pending
- 2002-06-14 RU RU2004100843/15A patent/RU2296565C2/ru not_active IP Right Cessation
- 2002-06-14 AT AT02745529T patent/ATE304354T1/de not_active IP Right Cessation
-
2003
- 2003-12-08 IS IS7067A patent/IS2367B/is unknown
- 2003-12-12 NO NO20035553A patent/NO20035553D0/no not_active Application Discontinuation
-
2005
- 2005-11-17 US US11/281,864 patent/US7402602B2/en not_active Expired - Fee Related
-
2006
- 2006-11-27 US US11/604,522 patent/US20070099975A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2449916A1 (fr) | 2002-12-27 |
| US7402602B2 (en) | 2008-07-22 |
| ES2249595T3 (es) | 2006-04-01 |
| JP2005500297A (ja) | 2005-01-06 |
| NO20035553D0 (no) | 2003-12-12 |
| CZ20033550A3 (cs) | 2005-05-18 |
| DK1401432T3 (da) | 2006-02-06 |
| DE60206171D1 (de) | 2005-10-20 |
| EP1401432A2 (de) | 2004-03-31 |
| DE60206171T2 (de) | 2006-06-22 |
| US20060069146A1 (en) | 2006-03-30 |
| KR20040030672A (ko) | 2004-04-09 |
| CZ297321B6 (cs) | 2006-11-15 |
| EP1401432B1 (de) | 2005-09-14 |
| PL366722A1 (en) | 2005-02-07 |
| IS2367B (is) | 2008-06-15 |
| BR0210285A (pt) | 2004-06-29 |
| NZ529741A (en) | 2006-10-27 |
| RU2004100843A (ru) | 2005-04-10 |
| US20070099975A1 (en) | 2007-05-03 |
| US20040198792A1 (en) | 2004-10-07 |
| HUP0400195A3 (en) | 2004-10-28 |
| FR2825926A1 (fr) | 2002-12-20 |
| RU2296565C2 (ru) | 2007-04-10 |
| HUP0400195A2 (hu) | 2004-07-28 |
| WO2002102375A3 (fr) | 2003-09-25 |
| CN1535148A (zh) | 2004-10-06 |
| WO2002102375A2 (fr) | 2002-12-27 |
| IS7067A (is) | 2003-12-08 |
| MXPA03011508A (es) | 2004-03-18 |
| US7157483B2 (en) | 2007-01-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE304354T1 (de) | Kaliumkanal-modulierende imidazolderivate | |
| NO20021358L (no) | Alkylendiamin-substituerte heterocykler | |
| EA200501009A1 (ru) | Замещённые пирролопиразольные производные в качестве ингибиторов киназы | |
| MXPA05007513A (es) | Compuestos, composiciones y metodos. | |
| EA200300829A1 (ru) | Производные 1-арил- или 1-алкилсульфонилбензазола в качестве лигандов 5-гидрокситриптамина-6 | |
| MY140767A (en) | Compounds, methods and compositions | |
| SE0401971D0 (sv) | Piperidne derivatives | |
| ATE525067T1 (de) | Amino-substituierte (e)-2,6-dialkoxystyryl 4- substituierte benzylsulfone zur behandlung von proliferierenden erkrankungen | |
| ATE233274T1 (de) | Oxyiminopregnancarbolactone | |
| TW200500339A (en) | Pyrrolidine derivatives, and process for the preparation | |
| DK1483251T3 (da) | C3-cyano-epothilon-derivater | |
| DK1594885T3 (da) | Lægemiddel til vækstinhibering af tumorer | |
| ATE498600T1 (de) | Inden derivate als pharmazeutika | |
| MXPA05013905A (es) | Compuestos de quinazolinona sustituidos por arilamina. | |
| ATE549024T1 (de) | Chinazolin-kaliumkanalhemmer | |
| SE0203303D0 (sv) | Novel Compounds | |
| DE60311887D1 (de) | Multifunktionelle kationische photoinitiatoren, deren herstellung und verwendung | |
| TR200302288T2 (tr) | Terapi için yeni bileşikler ve metotlar. | |
| SE0203300D0 (sv) | Novel Compounds | |
| SE0300105D0 (sv) | Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof | |
| NZ552328A (en) | Arylsulphonylstilbene derivatives for treatment of insomnia and related conditions | |
| ATE276259T1 (de) | Dihydroporphyrinderivate und ihre verwendung | |
| TW200510312A (en) | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof | |
| SE0203301D0 (sv) | Novel Compounds | |
| EA200401432A1 (ru) | Сложноэфирные производные декагидроизохинолин-3-карбоновой кислоты в качестве анальгетиков |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1401432 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |