ATE296801T1 - Tetrahydrobezindol derivate - Google Patents
Tetrahydrobezindol derivateInfo
- Publication number
- ATE296801T1 ATE296801T1 AT97928490T AT97928490T ATE296801T1 AT E296801 T1 ATE296801 T1 AT E296801T1 AT 97928490 T AT97928490 T AT 97928490T AT 97928490 T AT97928490 T AT 97928490T AT E296801 T1 ATE296801 T1 AT E296801T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- lower alkyl
- hydrogen atom
- carbamoyl
- alkoxycarbonyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
- C07D209/92—Naphthostyrils
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16970296 | 1996-06-28 | ||
| JP9627197 | 1997-04-15 | ||
| JP13020197 | 1997-05-21 | ||
| JP14437697 | 1997-06-03 | ||
| PCT/JP1997/002226 WO1998000400A1 (fr) | 1996-06-28 | 1997-06-27 | Composes de tetrahydrobenzindole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE296801T1 true ATE296801T1 (de) | 2005-06-15 |
Family
ID=27468418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97928490T ATE296801T1 (de) | 1996-06-28 | 1997-06-27 | Tetrahydrobezindol derivate |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6355642B1 (de) |
| EP (1) | EP0937715B1 (de) |
| JP (1) | JP4076234B2 (de) |
| AT (1) | ATE296801T1 (de) |
| DE (1) | DE69733427T2 (de) |
| ES (1) | ES2243999T3 (de) |
| NO (1) | NO311515B1 (de) |
| WO (1) | WO1998000400A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1129578C (zh) | 1997-12-25 | 2003-12-03 | 明治制果株式会社 | 四氢苯并吲哚衍生物 |
| KR20010042904A (ko) | 1998-04-22 | 2001-05-25 | 기따자또 이찌로 | 광학 활성 테트라하이드로벤즈인돌 유도체 |
| US6960579B1 (en) | 1998-05-19 | 2005-11-01 | Alcon Manufacturing, Ltd. | Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders |
| GB9828004D0 (en) * | 1998-12-18 | 1999-02-10 | Smithkline Beecham Plc | Use |
| AU1025601A (en) * | 1999-10-18 | 2001-04-30 | Smithkline Beecham Plc | Tetrahydrobenzindolone derivatives, their preparation and their use as 5-ht7 receptor antagonists |
| JP2004231514A (ja) * | 2000-08-31 | 2004-08-19 | Meiji Seika Kaisha Ltd | ５−ｈｔ７受容体結合能を有し、かつ代謝的に安定なテトラヒドロベンズインドール誘導体 |
| ITRM20010356A1 (it) * | 2001-06-21 | 2002-12-23 | Sigma Tau Ind Farmaceuti | "5-alogeno derivati della triptamina utili come ligandi del recettore5-ht6 e/o 5-ht7 della serotonina. |
| US7786094B2 (en) * | 2001-10-09 | 2010-08-31 | Biopolymer Engineering, Inc. | Use of beta-glucans against biological warfare weapons and pathogens including anthrax |
| US7553965B2 (en) | 2002-11-07 | 2009-06-30 | Laboratories Del Dr. Esteve, S.A. | 5-HT7 receptor antagonists |
| EP1676840A1 (de) | 2004-12-28 | 2006-07-05 | Laboratorios Del Dr. Esteve, S.A. | 5-HT7-Rezeptorantagonisten |
| US20070179155A1 (en) * | 2003-06-20 | 2007-08-02 | Brian Smith | N-phenyl-piperazine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases |
| NZ545836A (en) * | 2003-09-17 | 2009-09-25 | Janssen Pharmaceutica Nv | Fused heterocyclic compounds as serotonin receptor modulators |
| US20070265300A1 (en) * | 2004-05-11 | 2007-11-15 | Egis Gyogyszergyar Rt. | Pyridine Derivatives of Alkyl Oxindoles as 5-Ht7 Receptor Active Agents |
| TW200633721A (en) * | 2004-12-14 | 2006-10-01 | Shionogi & Co | A pharmaceutical composition for treating constipation |
| US20090029979A1 (en) * | 2005-07-07 | 2009-01-29 | Bio-Medisinsk Innovasjon As | 5-htx modulators |
| EP1917255A2 (de) | 2005-07-29 | 2008-05-07 | F. Hoffmann-Roche AG | Indol-3-yl-carbonyl-piperidin- und piperazin-derivate |
| US7598255B2 (en) * | 2005-08-04 | 2009-10-06 | Janssen Pharmaceutica Nv | Pyrimidine compounds as serotonin receptor modulators |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0429341A3 (en) * | 1989-11-20 | 1991-11-13 | Rhone-Poulenc Sante | Heterocyclic derivatives, their preparation and pharmaceuticals containing them |
| FR2662696A2 (fr) | 1989-12-13 | 1991-12-06 | Rhone Poulenc Sante | Antagonistes de la serotonine, leur preparation et medicaments les contenant. |
| US5077293A (en) * | 1990-06-29 | 1991-12-31 | Bristol-Myers Squibb Co. | 1-indolyalkyl-4-(alkoxypyrimidinyl)piperazines |
| JP3190858B2 (ja) | 1997-07-23 | 2001-07-23 | 山形日本電気株式会社 | 半導体装置およびその製造方法 |
-
1997
- 1997-06-27 AT AT97928490T patent/ATE296801T1/de not_active IP Right Cessation
- 1997-06-27 ES ES97928490T patent/ES2243999T3/es not_active Expired - Lifetime
- 1997-06-27 US US09/214,114 patent/US6355642B1/en not_active Expired - Lifetime
- 1997-06-27 WO PCT/JP1997/002226 patent/WO1998000400A1/ja active IP Right Grant
- 1997-06-27 EP EP97928490A patent/EP0937715B1/de not_active Expired - Lifetime
- 1997-06-27 JP JP50398498A patent/JP4076234B2/ja not_active Expired - Fee Related
- 1997-06-27 DE DE69733427T patent/DE69733427T2/de not_active Expired - Lifetime
-
1998
- 1998-12-28 NO NO19986141A patent/NO311515B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69733427T2 (de) | 2006-04-27 |
| NO986141L (no) | 1999-02-17 |
| JP4076234B2 (ja) | 2008-04-16 |
| ES2243999T3 (es) | 2005-12-01 |
| EP0937715B1 (de) | 2005-06-01 |
| DE69733427D1 (de) | 2005-07-07 |
| NO311515B1 (no) | 2001-12-03 |
| US6355642B1 (en) | 2002-03-12 |
| EP0937715A1 (de) | 1999-08-25 |
| WO1998000400A1 (fr) | 1998-01-08 |
| EP0937715A4 (de) | 2001-01-17 |
| NO986141D0 (no) | 1998-12-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |