ATE294875T1 - Kationische polyacrylate und poly(alkyl)acrylate oder die entsprechende acrylamide zur verwendung in synthetischen transfektions-systemen - Google Patents

Kationische polyacrylate und poly(alkyl)acrylate oder die entsprechende acrylamide zur verwendung in synthetischen transfektions-systemen

Info

Publication number
ATE294875T1
ATE294875T1 AT96935575T AT96935575T ATE294875T1 AT E294875 T1 ATE294875 T1 AT E294875T1 AT 96935575 T AT96935575 T AT 96935575T AT 96935575 T AT96935575 T AT 96935575T AT E294875 T1 ATE294875 T1 AT E294875T1
Authority
AT
Austria
Prior art keywords
poly
alkyl
acrylates
cationic
polyacrylate
Prior art date
Application number
AT96935575T
Other languages
English (en)
Inventor
Wilhelmus Everhardus Hennink
De Wetering Petra Van
Original Assignee
Octoplus B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Octoplus B V filed Critical Octoplus B V
Application granted granted Critical
Publication of ATE294875T1 publication Critical patent/ATE294875T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
AT96935575T 1995-10-25 1996-10-25 Kationische polyacrylate und poly(alkyl)acrylate oder die entsprechende acrylamide zur verwendung in synthetischen transfektions-systemen ATE294875T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP95202891 1995-10-25
US592395P 1995-10-27 1995-10-27
PCT/NL1996/000416 WO1997015680A1 (en) 1995-10-25 1996-10-25 Cationic polyacrylates and poly(alkyl) acrylates or the corresponding acrylamides for use in synthetic transfection or blocking systems

Publications (1)

Publication Number Publication Date
ATE294875T1 true ATE294875T1 (de) 2005-05-15

Family

ID=26139739

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96935575T ATE294875T1 (de) 1995-10-25 1996-10-25 Kationische polyacrylate und poly(alkyl)acrylate oder die entsprechende acrylamide zur verwendung in synthetischen transfektions-systemen

Country Status (8)

Country Link
US (1) US5985573A (de)
EP (1) EP0859857B1 (de)
JP (1) JP3957084B2 (de)
AT (1) ATE294875T1 (de)
AU (1) AU7342296A (de)
DE (1) DE69634697T2 (de)
ES (1) ES2242198T3 (de)
WO (1) WO1997015680A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0965583A1 (de) * 1998-06-15 1999-12-22 Transgene S.A. Zum Einschleusen von Wirkstoffen in Zellen geeignete Polyamin-Verbindungen und diese enthaltende Zusammensetzungen
EP0965584A3 (de) * 1998-06-15 2003-12-17 Transgene S.A. Zum Einschleusen von Wirkstoffen in Zellen geeignete Polyamin-Verbindungen und diese enthaltende Zusammensetzungen
US20050153926A1 (en) * 1998-12-04 2005-07-14 Adams Christopher P. Method for the immobilization of oligonucleotides
EP1022340A1 (de) * 1999-01-21 2000-07-26 OctoPlus B.V. Stabilisierung von Zusammensetzungen die nicht-virale nukeinsäure-Transfer-Zusammensetzungen enthalten
WO2004030455A1 (en) * 2002-10-03 2004-04-15 Agroshield, Llc Polymers for protecting materials from damage
WO2004087228A1 (ja) * 2003-03-28 2004-10-14 Japan Science And Technology Agency 生体適合性と温度応答性を併せ持つ高分子
WO2004092388A1 (ja) * 2003-04-18 2004-10-28 Japan As Represented By President Of National Cardiovascular Center ベクター
JP4718766B2 (ja) * 2003-06-03 2011-07-06 テルモ株式会社 血液フィルター
EP1505089B1 (de) * 2003-08-07 2006-01-11 OctoPlus Technologies B.V. Kationisches (Alkyl)acrylamid, hiervon abgeleitetes Polymeres sowie dieses enthaltendes Transfektions-System
US20090123468A1 (en) 2003-10-24 2009-05-14 Gencia Corporation Transducible polypeptides for modifying metabolism
US8062891B2 (en) 2003-10-24 2011-11-22 Gencia Corporation Nonviral vectors for delivering polynucleotides to plants
US8133733B2 (en) 2003-10-24 2012-03-13 Gencia Corporation Nonviral vectors for delivering polynucleotides to target tissues
US8507277B2 (en) 2003-10-24 2013-08-13 Gencia Corporation Nonviral vectors for delivering polynucleotides
CA2543257C (en) 2003-10-24 2013-12-31 Gencia Corporation Methods and compositions for delivering polynucleotides
US7786194B2 (en) * 2004-04-02 2010-08-31 Agroshield, Llc Compositions and methods for protecting materials from damage
CN100566755C (zh) * 2004-04-05 2009-12-09 巴斯福股份公司 包含活性剂的聚合物颗粒
EP1595534A1 (de) * 2004-05-13 2005-11-16 Universiteit Utrecht Holding B.V. Gelzusammensetzung enthaltend geladenepolymere
DE102004059792A1 (de) 2004-12-10 2006-06-14 Röhm GmbH & Co. KG Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Nukleinsäure-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform
US20060211004A1 (en) 2005-02-15 2006-09-21 Ilsley Diane D Methods and compositions for determining non-specific cytotoxicity of a transfection agent
DE102008016275A1 (de) 2008-03-28 2009-11-19 Biontex Laboratories Gmbh Verbesserung von Transfektionsergebnissen nicht-viraler Genliefersysteme durch Blockierung des angeborenen Immunsystems
DE102008023913A1 (de) 2008-05-16 2009-11-19 Biontex Laboratories Gmbh Verbesserung von Transfektionsergebnissen nicht-viraler Genliefersysteme durch Beeinflussung des angeborenen Immunsystems
DE102007056488A1 (de) 2007-11-22 2009-07-23 Biontex Laboratories Gmbh Steigerung von Transfektionseffizienzen nicht-viraler Genliefersysteme durch Blockierung des angeborenen Immunsystems
WO2009065618A2 (de) 2007-11-22 2009-05-28 Biontex Laboratories Gmbh Verbesserung von transfektionsergebnissen nicht-viraler genliefersysteme durch beeinflussung des angeborenen immunsystems
WO2010150089A1 (en) * 2009-06-26 2010-12-29 Cedars-Sinai Medical Center Highly efficient systems for delivery of nucleic acids
US8678201B2 (en) * 2010-06-04 2014-03-25 Goodrich Corporation Aircraft potable water system
EP2522689A1 (de) 2011-05-13 2012-11-14 Universität Bayreuth Nicht virale Transfektionssysteme
US9283072B2 (en) 2012-07-25 2016-03-15 W. L. Gore & Associates, Inc. Everting transcatheter valve and methods
US9144492B2 (en) 2012-12-19 2015-09-29 W. L. Gore & Associates, Inc. Truncated leaflet for prosthetic heart valves, preformed valve
US9101469B2 (en) 2012-12-19 2015-08-11 W. L. Gore & Associates, Inc. Prosthetic heart valve with leaflet shelving
US9968443B2 (en) 2012-12-19 2018-05-15 W. L. Gore & Associates, Inc. Vertical coaptation zone in a planar portion of prosthetic heart valve leaflet
US9827094B2 (en) 2014-09-15 2017-11-28 W. L. Gore & Associates, Inc. Prosthetic heart valve with retention elements
JP7068444B2 (ja) 2017-09-27 2022-05-16 ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド 拡張可能なフレームを備えた人工弁、並びに関連するシステム及び方法
CA3155761A1 (en) 2017-09-27 2019-04-04 W.L. Gore & Associates, Inc. Prosthetic valves with mechanically coupled leaflets
US11154397B2 (en) 2017-10-31 2021-10-26 W. L. Gore & Associates, Inc. Jacket for surgical heart valve
CN111295158A (zh) 2017-10-31 2020-06-16 W.L.戈尔及同仁股份有限公司 医用瓣膜和促进组织向内生长的瓣叶
US11497601B2 (en) 2019-03-01 2022-11-15 W. L. Gore & Associates, Inc. Telescoping prosthetic valve with retention element

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5286634A (en) * 1989-09-28 1994-02-15 Stadler Joan K Synergistic method for host cell transformation
JPH0463597A (ja) * 1990-06-29 1992-02-28 W R Grace & Co 細胞への遺伝子導入法およびそれに用いる細胞固定板
DE4139001A1 (de) * 1991-11-27 1993-06-03 Boehringer Mannheim Gmbh Verfahren zur einschleusung von nukleinsaeuren in zellen

Also Published As

Publication number Publication date
WO1997015680A1 (en) 1997-05-01
ES2242198T3 (es) 2005-11-01
JP3957084B2 (ja) 2007-08-08
EP0859857B1 (de) 2005-05-04
JP2001508641A (ja) 2001-07-03
DE69634697T2 (de) 2006-05-04
AU7342296A (en) 1997-05-15
EP0859857A1 (de) 1998-08-26
US5985573A (en) 1999-11-16
DE69634697D1 (de) 2005-06-09

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