ATE290527T1 - Tetrahydrobenzindol-derivate - Google Patents
Tetrahydrobenzindol-derivateInfo
- Publication number
- ATE290527T1 ATE290527T1 AT98961493T AT98961493T ATE290527T1 AT E290527 T1 ATE290527 T1 AT E290527T1 AT 98961493 T AT98961493 T AT 98961493T AT 98961493 T AT98961493 T AT 98961493T AT E290527 T1 ATE290527 T1 AT E290527T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrogen atom
- integer
- group
- specified substituent
- lower alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
- C07D209/92—Naphthostyrils
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP35838197A JPH11189585A (ja) | 1997-12-25 | 1997-12-25 | ５−ｈｔ７受容体結合能を有するテトラヒドロベンズインドール誘導体 |
| JP35838097 | 1997-12-25 | ||
| JP8591398 | 1998-03-31 | ||
| JP13687298 | 1998-05-19 | ||
| JP22970998 | 1998-08-14 | ||
| JP31933698 | 1998-11-10 | ||
| PCT/JP1998/005827 WO1999033804A1 (fr) | 1997-12-25 | 1998-12-22 | Derives de tetrahydrobenzindole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE290527T1 true ATE290527T1 (de) | 2005-03-15 |
Family
ID=27551662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98961493T ATE290527T1 (de) | 1997-12-25 | 1998-12-22 | Tetrahydrobenzindol-derivate |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6498251B1 (de) |
| EP (1) | EP1057814B1 (de) |
| JP (1) | JP4459437B2 (de) |
| KR (1) | KR100588249B1 (de) |
| CN (1) | CN1129578C (de) |
| AT (1) | ATE290527T1 (de) |
| CA (1) | CA2316388C (de) |
| DE (1) | DE69829317T2 (de) |
| DK (1) | DK1057814T3 (de) |
| ES (1) | ES2238778T3 (de) |
| NO (1) | NO317293B1 (de) |
| WO (1) | WO1999033804A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010042904A (ko) * | 1998-04-22 | 2001-05-25 | 기따자또 이찌로 | 광학 활성 테트라하이드로벤즈인돌 유도체 |
| UA69420C2 (uk) * | 1998-10-06 | 2004-09-15 | Янссен Фармацевтика Н.В. | ТРИЦИКЛІЧНІ <font face="Symbol">D3</font>-ПІПЕРИДИНИ ЯК <font face="Symbol">a<sub></font>2</sub>-АНТАГОНІСТИ |
| GB9828004D0 (en) * | 1998-12-18 | 1999-02-10 | Smithkline Beecham Plc | Use |
| EP1222185A1 (de) * | 1999-10-18 | 2002-07-17 | Smithkline Beecham Plc | Tetrahydrobenzindolon-derivate, deren herstellung und deren verwendung als 5-ht7 rezeptor antagonisten |
| AR035417A1 (es) * | 2001-01-27 | 2004-05-26 | Hoffmann La Roche | Derivados triciclicos de lactama y sultama, procesos para su elaboracion, medicamentos que los contienen, y el uso de dichos compuestos en la preparacion de medicamentos |
| WO2004018432A1 (en) * | 2002-08-20 | 2004-03-04 | Eli Lilly And Company | Substituted azepines as histamine h3 receptor antagonists, preparation and therapeutic uses |
| JP4517381B2 (ja) * | 2003-08-04 | 2010-08-04 | 曽田香料株式会社 | チエノピリジン系化合物の香料における使用、および新規チエノピリジン系化合物 |
| JP2007537225A (ja) * | 2004-05-11 | 2007-12-20 | エギシュ ヂョヂセルヂャール エンニュ・エル・テー | ５−ｈｔ７活性剤としてのアルキルオキシインドールのピリジン誘導体 |
| CA2606471C (en) * | 2005-04-26 | 2014-02-11 | Hypnion, Inc. | Benzisoxazole piperidine compounds and methods of use thereof |
| WO2008015270A1 (en) * | 2006-08-04 | 2008-02-07 | Merz Pharma Gmbh & Co. Kgaa | Pyrazolopyrimidines, a process for their preparation and their use as medicine |
| EP1956006A1 (de) | 2007-02-06 | 2008-08-13 | Laboratorios del Dr. Esteve S.A. | Heterocyclisch substituierte Tetrahydronaphthalenderivate als 5-HT7 Rezeptorliganden |
| EP1975161A1 (de) * | 2007-03-28 | 2008-10-01 | Laboratorios del Dr. Esteve S.A. | Heterocyclyl-substituierte Tetrahydronaphthalenamin-Derivate, ihre Herstellung und Verwendung als Arzneimittel |
| BRPI0906244A2 (pt) | 2008-03-24 | 2015-06-30 | Medivation Technologies Inc | Composto, composição farmacêutica, método para tratar um distúrbio cognitivo, psicótico, mediado por neurotransmissores ou um distúrbio neuronal em um indivíduo, uso de um composto e kit |
| CN102711467A (zh) * | 2009-09-23 | 2012-10-03 | 梅迪维新技术公司 | 吡啶并[3,4-b]吲哚类及使用方法 |
| CN108623585B (zh) * | 2018-05-22 | 2021-07-09 | 中国人民解放军第二军医大学 | β-四氢咔啉类抗真菌药物及其制备方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998000400A1 (fr) | 1996-06-28 | 1998-01-08 | Meiji Seika Kaisha, Ltd. | Composes de tetrahydrobenzindole |
| KR20010042904A (ko) * | 1998-04-22 | 2001-05-25 | 기따자또 이찌로 | 광학 활성 테트라하이드로벤즈인돌 유도체 |
-
1998
- 1998-12-22 KR KR1020007007122A patent/KR100588249B1/ko not_active IP Right Cessation
- 1998-12-22 CN CN98813811A patent/CN1129578C/zh not_active Expired - Fee Related
- 1998-12-22 DE DE69829317T patent/DE69829317T2/de not_active Expired - Lifetime
- 1998-12-22 DK DK98961493T patent/DK1057814T3/da active
- 1998-12-22 AT AT98961493T patent/ATE290527T1/de not_active IP Right Cessation
- 1998-12-22 CA CA002316388A patent/CA2316388C/en not_active Expired - Fee Related
- 1998-12-22 US US09/582,416 patent/US6498251B1/en not_active Expired - Fee Related
- 1998-12-22 ES ES98961493T patent/ES2238778T3/es not_active Expired - Lifetime
- 1998-12-22 EP EP98961493A patent/EP1057814B1/de not_active Expired - Lifetime
- 1998-12-22 JP JP2000526488A patent/JP4459437B2/ja not_active Expired - Fee Related
- 1998-12-22 WO PCT/JP1998/005827 patent/WO1999033804A1/ja active IP Right Grant
-
2000
- 2000-06-22 NO NO20003285A patent/NO317293B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999033804A1 (fr) | 1999-07-08 |
| EP1057814A1 (de) | 2000-12-06 |
| DE69829317T2 (de) | 2006-04-06 |
| NO20003285L (no) | 2000-08-23 |
| CA2316388C (en) | 2009-09-08 |
| NO20003285D0 (no) | 2000-06-22 |
| EP1057814B1 (de) | 2005-03-09 |
| JP4459437B2 (ja) | 2010-04-28 |
| US6498251B1 (en) | 2002-12-24 |
| NO317293B1 (no) | 2004-10-04 |
| CN1129578C (zh) | 2003-12-03 |
| ES2238778T3 (es) | 2005-09-01 |
| EP1057814A4 (de) | 2001-07-11 |
| KR20010033609A (ko) | 2001-04-25 |
| DK1057814T3 (da) | 2005-07-04 |
| CN1286683A (zh) | 2001-03-07 |
| KR100588249B1 (ko) | 2006-06-13 |
| DE69829317D1 (de) | 2005-04-14 |
| CA2316388A1 (en) | 1999-07-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |