ATE283858T1 - Verbindungen zur pdt - Google Patents

Verbindungen zur pdt

Info

Publication number
ATE283858T1
ATE283858T1 AT01910017T AT01910017T ATE283858T1 AT E283858 T1 ATE283858 T1 AT E283858T1 AT 01910017 T AT01910017 T AT 01910017T AT 01910017 T AT01910017 T AT 01910017T AT E283858 T1 ATE283858 T1 AT E283858T1
Authority
AT
Austria
Prior art keywords
isocyanate
isothiocyanate
group
derivatised
alkylene oxide
Prior art date
Application number
AT01910017T
Other languages
English (en)
Inventor
Paul Bradley
Mehar Manku
Original Assignee
Biolitec Pharma Marketing Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biolitec Pharma Marketing Ltd filed Critical Biolitec Pharma Marketing Ltd
Application granted granted Critical
Publication of ATE283858T1 publication Critical patent/ATE283858T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Polyethers (AREA)
AT01910017T 2000-03-10 2001-03-08 Verbindungen zur pdt ATE283858T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0005855.2A GB0005855D0 (en) 2000-03-10 2000-03-10 Compounds for pdt
PCT/GB2001/001010 WO2001066550A2 (en) 2000-03-10 2001-03-08 Compounds for pdt

Publications (1)

Publication Number Publication Date
ATE283858T1 true ATE283858T1 (de) 2004-12-15

Family

ID=9887409

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01910017T ATE283858T1 (de) 2000-03-10 2001-03-08 Verbindungen zur pdt

Country Status (11)

Country Link
US (1) US7375215B2 (de)
EP (1) EP1263761B1 (de)
JP (1) JP2003525942A (de)
KR (1) KR20020093833A (de)
AT (1) ATE283858T1 (de)
AU (1) AU3760101A (de)
BR (1) BR0109135A (de)
CA (1) CA2402433A1 (de)
DE (1) DE60107547T2 (de)
GB (1) GB0005855D0 (de)
WO (1) WO2001066550A2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1450790A4 (de) * 2001-10-03 2005-10-26 Miravant Pharm Inc Photosensibilisierende carbamat-derivate
PT102721B (pt) * 2002-02-01 2011-01-24 Cipan Companhia Industr Prod De Antibioticos S A Compostos macrocíclicos tetrapirrólicos com rendimento quântico de oxigénio singuleto adequado à terapia fotodinâmica e processos para a sua preparação
US6949581B2 (en) 2003-03-21 2005-09-27 Ceramoptec Industries, Inc. Water-soluble mono-PEGylated tetrapyrrole derivatives for photodynamic therapy and method of production
CA2437638A1 (en) 2003-08-20 2005-02-20 John Robert North Photodynamic therapy
US20050048109A1 (en) * 2003-08-26 2005-03-03 Ceramoptec Industries, Inc. Non-polar photosensitizer formulations for photodynamic therapy
CA2457214A1 (en) 2004-02-06 2005-08-06 Qlt Inc. Photodynamic therapy for the treatment of acne
NZ551636A (en) 2004-06-09 2009-12-24 Quadra Logic Tech Inc Photodynamic therapy for the treatment of hyperactive sebaceous gland disorders using topically applied hydrophobic green porphyrins
JPWO2006095708A1 (ja) * 2005-03-08 2008-08-14 国立大学法人 奈良先端科学技術大学院大学 ポルフィリン化合物及びその利用
US8999933B2 (en) * 2006-01-18 2015-04-07 Biolitec Pharma Marketing Ltd Photodynamic cosmetic procedure and healing method
CZ2006743A3 (cs) * 2006-11-28 2008-03-26 Fyziologický ústav AV CR Liposomální gelový ftalocyaninový prípravek pro fotodynamickou terapii nádorových onemocnení a zpusob jeho prípravy
US20090036952A1 (en) 2007-07-30 2009-02-05 National Yang-Ming University Induction driven light module and use thereof
CN102249939B (zh) * 2010-05-19 2014-07-09 中国科学院理化技术研究所 脂水两亲性亚苄基环戊酮染料及其制备方法与在光动力治疗中的用途
CN102249940B (zh) * 2010-05-19 2014-04-16 中国科学院理化技术研究所 脂水两亲性亚苄基环戊酮染料及其合成方法与在双光子光动力治疗中的用途
CN103169968B (zh) * 2013-03-12 2014-11-26 中国科学院理化技术研究所 一种基于白蛋白的疏水二氢卟吩光敏剂纳米药物制剂、制备方法及其应用
CZ307681B6 (cs) 2016-02-29 2019-02-13 Ústav makromolekulární chemie AV ČR, v. v. i. Fotoaktivovatelná nanočástice pro fotodynamické aplikace, způsob její přípravy, farmaceutická kompozice ji obsahující a jejich použití
CN108715591B (zh) * 2018-06-01 2021-04-13 华东理工大学 用作光敏剂的近红外吸收卟啉化合物及其应用
CN109096290A (zh) * 2018-11-08 2018-12-28 西北师范大学 含丙酮席夫碱水溶性卟啉及金属Cu(II)配合物的合成与应用
RU2771237C1 (ru) * 2021-06-04 2022-04-28 федеральное государственное автоносное образовательное учреждение высшего образования «Национальный исследовательский Томский политехнический университет» Сенсибилизатор для фотодинамического разрушения опухолевых клеток

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59103985D1 (en) * 1990-05-30 1995-02-02 Deutsches Krebsforsch Polyethersubstituierte tumormittel.
GB9408746D0 (en) * 1994-05-03 1994-06-22 Scotia Holdings Plc Tumour locallising photosensitising compounds
DE19627164C2 (de) * 1996-07-05 1998-09-24 Deutsches Krebsforsch Herstellung polyether-aufweisender Chlorine und Bakteriochlorine, solche Verbindungen und ihre Verwendung
DE19706490C1 (de) * 1997-02-19 1998-09-17 Deutsches Krebsforsch Verfahren zur Herstellung von Säureamiden und zur Metallierung von Verbindungen und Verwendung der nach den Verfahren hergestellten Verbindungen
US20020155999A1 (en) * 1998-04-30 2002-10-24 Han In Suk Method of using a porphyrin-like molecule conjugated with an anti-cancer drug for the treatment of cancer

Also Published As

Publication number Publication date
WO2001066550A3 (en) 2001-12-20
KR20020093833A (ko) 2002-12-16
EP1263761B1 (de) 2004-12-01
WO2001066550A2 (en) 2001-09-13
CA2402433A1 (en) 2001-09-13
US7375215B2 (en) 2008-05-20
BR0109135A (pt) 2002-12-24
DE60107547T2 (de) 2005-12-15
JP2003525942A (ja) 2003-09-02
EP1263761A2 (de) 2002-12-11
US20060040912A1 (en) 2006-02-23
GB0005855D0 (en) 2000-05-03
DE60107547D1 (de) 2005-01-05
AU3760101A (en) 2001-09-17

Similar Documents

Publication Publication Date Title
ATE283858T1 (de) Verbindungen zur pdt
AR005180A1 (es) Elastomero de poliuretano, metodo para aumentar las propiedades fisicas del mismo y prepolimero o cuasiprepolimero terminado con isocianato para prepararlo
PL1694795T3 (pl) System do łączenia szkła z konstrukcją
MX9603549A (es) Catalizadores mejorados de cianuro dimetalico que contiene polieter.
HU9502027D0 (en) Small cell foams and blends and a process for their preparation
AR041067A1 (es) Formulacion estable de un anticuerpo modificado con el ph optimizado
DE60022313D1 (de) Alternansucrase-kodierende nukleinsäure moleküle
DK1537159T4 (da) Fremgangsmåde til fremstilling af emissionsfattige bløde skumstoffer af polyurethan
EA200600856A1 (ru) Гербицидно действующее средство
TW200621686A (en) Process for the preparation of liquid, storage-stable organic isocyanates of low color number containing carbodiimide and/or uretonimine groups
DK1185630T3 (da) Kemisk modificeret lipolytisk enzym
TW200604736A (en) A star polymer
WO2006119309A3 (en) 19,26,27-TRINOR-1α,25-DIHYDROXYVITAMIN D3 COMPOUNDS
DE602005004147D1 (de) Polyurethan, enthaltend eine polyolzusammensetzung, die ein hochverzweigtes polysaccharid umfasst, mischung und herstellungsverfahren dafür
MXPA03010376A (es) Procedimiento para preparacion de poliisocianatos alifaticos con estructura uretodiona, isocianurato asi como iminooxadiazindiona.
ATE527324T1 (de) Gefärbte wasserverteilbare polyurethane
BRPI0416657A (pt) composições de poliuretano com reatividade do grupo nco e silila
EP0273368A3 (de) Verfahren zur Herstellung von hitzehärtbaren Harzen
DE50204812D1 (de) Polyurethane und ihre Verwendung zur Verdickung wässriger Systeme
BR0301726A (pt) Poliuretano/uréias úteis para a produção de spandex e processo para a sua produção
DE502006005337D1 (de) Prepolymere und daraus hergestellte zellige polyisocyanat-polyadditionsprodukte
BR0011625A (pt) Poliuretanos de poliuréia com propriedades fìsicas aperfeiçoadas
TW200508453A (en) Polyurethane and synthetic leather surface coating using the same
ES2132317T3 (es) Isocianuratos prolongados para el uso como agentes de endurecimiento en composiciones de revestimiento.
WO2002086112A3 (en) Nucleic acid molecules encoding starch degrading enzymes

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties