|
US6096721A
(en)
*
|
1995-04-13 |
2000-08-01 |
Milkhaus Laboratory, Inc. |
Method for treating mucositis by sublingual administration of DNA
|
|
US5948768A
(en)
*
|
1995-04-13 |
1999-09-07 |
Milkhaus Laboratory |
Treatment of otitis media by sublingual administration of DNA
|
|
WO1996032138A1
(en)
*
|
1995-04-13 |
1996-10-17 |
Milkhaus Laboratory, Inc. |
Methods for treating respiratory disease
|
|
US5635160A
(en)
*
|
1995-06-07 |
1997-06-03 |
The University Of North Carolina At Chapel Hill |
Dinucleotides useful for the treatment of cystic fibrosis and for hydrating mucus secretions
|
|
US5628984A
(en)
*
|
1995-07-31 |
1997-05-13 |
University Of North Carolina At Chapel Hill |
Method of detecting lung disease
|
|
US5968913A
(en)
*
|
1996-07-03 |
1999-10-19 |
Inspire Pharmaceuticals, Inc. |
Pharmaceutical compositions of uridine triphosphate
|
|
US6319908B1
(en)
|
1996-07-03 |
2001-11-20 |
Inspire Pharmaceuticals, Inc. |
Method for large-scale production of di(uridine 5′-tetraphosphate) and salts thereof
|
|
US5763447C1
(en)
|
1996-07-23 |
2002-05-07 |
Inspire Pharmaceuticals |
Method of preventing or treating pneumonia in immobilized patients with uridine triphosphates and related compounds
|
|
US6159952A
(en)
*
|
1996-11-07 |
2000-12-12 |
Inspire Pharmaceuticals, Inc. |
Method of treating bronchitis with uridine triphosphate and related compounds
|
|
US6998121B2
(en)
|
2003-01-23 |
2006-02-14 |
Milkhaus Laboratory, Inc. |
Method of treatment of connective tissue disorders by administration of streptolysin O
|
|
WO1999005155A2
(en)
|
1997-07-25 |
1999-02-04 |
Inspire Pharmaceuticals, Inc. |
Salts of di(uridine 5'-tetraphosphate), method for preparation and uses thereof
|
|
TW593331B
(en)
|
1997-07-25 |
2004-06-21 |
Inspire Pharmaceuticals Inc |
Method for large-scale production of di(uridine 5')-tetraphosphate and salts thereof
|
|
US6872710B2
(en)
*
|
1997-07-25 |
2005-03-29 |
Inspire Pharmaceuticals, Inc. |
Di(uridine 5′)-tetraphosphate and salts thereof
|
|
EP1011688B1
(en)
*
|
1997-08-29 |
2005-02-02 |
The University of North Carolina at Chapel Hill |
Use of uridine 5'-diphosphate and analogs thereof for the treatment of lung diseases
|
|
EP2258183A1
(en)
*
|
1998-12-22 |
2010-12-08 |
The University of North Carolina at Chapel Hill |
Compounds and uses for the treatment of airway diseases and for the delivery of airway drugs
|
|
US6926911B1
(en)
*
|
1998-12-22 |
2005-08-09 |
The University Of North Carolina At Chapel Hill |
Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs
|
|
DE60015734D1
(de)
|
1999-02-26 |
2004-12-16 |
Inspire Pharmaceuticals Durham |
Verwendung von dinukleotidtriphosphaten, cytidindiphosphaten und adenindiphosphaten zur herstellung einer pharmazeutischen zubereitung zur förderung der schleimauthydratation
|
|
JP4969002B2
(ja)
*
|
1999-06-08 |
2012-07-04 |
ユニバーシテイ・オブ・アイオワ・リサーチ・フアウンデーシヨン |
rAAV形質導入を増加するための化合物および方法
|
|
US7241447B1
(en)
*
|
1999-10-07 |
2007-07-10 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors and uses thereof
|
|
US7018985B1
(en)
|
2000-08-21 |
2006-03-28 |
Inspire Pharmaceuticals, Inc. |
Composition and method for inhibiting platelet aggregation
|
|
US7452870B2
(en)
*
|
2000-08-21 |
2008-11-18 |
Inspire Pharmaceuticals, Inc. |
Drug-eluting stents coated with P2Y12 receptor antagonist compound
|
|
US7115585B2
(en)
*
|
2000-08-21 |
2006-10-03 |
Inspire Pharmaceuticals, Inc. |
Compositions for treating epithelial and retinal tissue diseases
|
|
JP2005508297A
(ja)
|
2001-06-25 |
2005-03-31 |
インスパイアー ファーマシューティカルズ,インコーポレイティド |
P2yプリン受容体作用物質による関節潤滑
|
|
JP3823162B2
(ja)
*
|
2001-07-31 |
2006-09-20 |
株式会社エイアンドティー |
臨床検査分析装置、臨床検査分析方法および臨床検査分析プログラム
|
|
JP2005532254A
(ja)
*
|
2001-11-06 |
2005-10-27 |
インスパイアー ファーマシューティカルズ,インコーポレイティド |
炎症性疾患を治療又は予防する方法
|
|
US20060196365A1
(en)
*
|
2001-12-11 |
2006-09-07 |
Garman Michael H |
Combined water cooler and hot beverage maker
|
|
US6858615B2
(en)
|
2002-02-19 |
2005-02-22 |
Parion Sciences, Inc. |
Phenyl guanidine sodium channel blockers
|
|
US7435724B2
(en)
|
2002-02-27 |
2008-10-14 |
Inspire Pharmaceutical, Inc. |
Degradation-resistant mononucleoside phosphate compounds
|
|
US20050220720A1
(en)
*
|
2002-05-02 |
2005-10-06 |
David Edwards |
Formulations limiting spread of pulmonary infections
|
|
WO2003092654A1
(en)
|
2002-05-02 |
2003-11-13 |
President And Fellows Of Harvard College |
Formulations limiting spread of pulmonary infections
|
|
US7629312B2
(en)
|
2003-01-23 |
2009-12-08 |
Milkhaus Laboratory, Inc. |
Method of treatment of tendonitis by administration of streptolysin O
|
|
AU2004227358B8
(en)
*
|
2003-03-31 |
2009-12-10 |
Targeted Genetics Corporation |
Compounds and methods to enhance rAAV transduction
|
|
JP5030587B2
(ja)
|
2003-06-26 |
2012-09-19 |
バイオトロン・リミテッド |
抗ウイルスアシルグアニジン化合物および方法
|
|
US7745442B2
(en)
|
2003-08-20 |
2010-06-29 |
Parion Sciences, Inc. |
Methods of reducing risk of infection from pathogens
|
|
US20090253714A1
(en)
*
|
2003-08-20 |
2009-10-08 |
Johnson Michael R |
Methods of reducing risk of infection from pathogens
|
|
EP1689705A4
(en)
*
|
2003-11-24 |
2007-08-29 |
Univ North Carolina |
DIAGNOSTIC ANTIPROTOZOENOMENTS WITH CONDENSED RING AND PRODRUGS THEREOF
|
|
US20050207983A1
(en)
*
|
2004-03-05 |
2005-09-22 |
Pulmatrix, Inc. |
Formulations decreasing particle exhalation
|
|
US20070276020A1
(en)
*
|
2004-03-08 |
2007-11-29 |
Boykin David W |
Dicationic Compounds For Activity Against Trichomonas Vaginalis
|
|
US20070099968A1
(en)
*
|
2004-06-26 |
2007-05-03 |
Biotron Limited |
Antiviral compounds and methods
|
|
GB0417886D0
(en)
*
|
2004-08-11 |
2004-09-15 |
Univ Cardiff |
Method and means for enhanced pulmonary delivery
|
|
WO2006096757A2
(en)
|
2005-03-07 |
2006-09-14 |
The University Of North Carolina At Chapel Hill |
Inhibitors of reca activities for control of antibiotic-resistant bacterial pathogens
|
|
AU2006201739A1
(en)
*
|
2005-05-05 |
2006-11-23 |
The University Of North Carolina At Chapel Hill |
Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles
|
|
AU2006247077A1
(en)
*
|
2005-05-18 |
2006-11-23 |
Pulmatrix Inc. |
Formulations for alteration of biophysical properties of mucosal lining
|
|
US7964619B2
(en)
|
2005-06-03 |
2011-06-21 |
The University Of North Carolina At Chapel Hill |
Teraryl components as antiparasitic agents
|
|
US8101636B2
(en)
|
2005-06-03 |
2012-01-24 |
The University Of North Carolina At Chapel Hill |
Linear dicationic terphenyls and their aza analogues as antiparasitic agents
|
|
US20100249175A1
(en)
*
|
2005-12-02 |
2010-09-30 |
Wilson W David |
Dicationic compounds which selectively recognize G-quadruplex DNA
|
|
WO2007127464A2
(en)
*
|
2006-04-28 |
2007-11-08 |
University Of Iowa Research Foundation |
Methods and compounds to modulate parvovirus transduction of mammalian cells or to alter virus infection, method to identify a viral receptor or co-receptor
|
|
US20080260863A1
(en)
*
|
2007-04-20 |
2008-10-23 |
Pre Holding, Inc. |
Compositions for mucociliary clearance and methods for administering same
|
|
AU2008266856A1
(en)
|
2007-06-18 |
2008-12-24 |
University Of Louisville Research Foundation, Inc. |
Family of PFKFB3 inhibitors with anti-neoplastic activities
|
|
US20100280098A1
(en)
*
|
2007-10-05 |
2010-11-04 |
Juliano Rudolph L |
Receptor targeted oligonucleotides
|
|
US8551534B2
(en)
|
2007-10-10 |
2013-10-08 |
Parion Sciences, Inc. |
Inhaled hypertonic saline delivered by a heated nasal cannula
|
|
WO2009051796A2
(en)
*
|
2007-10-17 |
2009-04-23 |
The University Of North Carolina At Chapel Hill |
2,5-diaryl selenophene compounds, aza 2,5-diaryl thiophene compounds, and their prodrugs as antiprotozoal agents
|
|
KR20100135886A
(ko)
|
2008-04-09 |
2010-12-27 |
더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 |
액틴 세포 골격의 재배열 및 세포간 갭 형성을 조절하는 방법
|
|
CN102231983A
(zh)
*
|
2008-10-01 |
2011-11-02 |
北卡罗来纳大学查珀尔希尔分校 |
使用选择性细胞周期蛋白依赖性激酶4/6抑制剂对抗电离辐射的造血防护
|
|
JP2012504646A
(ja)
*
|
2008-10-01 |
2012-02-23 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
選択的サイクリン依存性キナーゼ4/6阻害剤を用いた化学療法化合物に対する造血系の防護
|
|
ES2625260T5
(es)
|
2009-03-26 |
2020-07-29 |
Pulmatrix Operating Co Inc |
Formulaciones de polvo seco y métodos para el tratamiento de enfermedades pulmonares
|
|
JP2012526850A
(ja)
|
2009-05-13 |
2012-11-01 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
サイクリン依存性キナーゼ阻害剤及びその用法
|
|
CA2768154C
(en)
|
2009-07-13 |
2018-02-13 |
Irix Pharmaceuticals |
Synthesis of prostanoids
|
|
CA2768582C
(en)
|
2009-07-24 |
2017-02-14 |
University Of Tennessee Research Foundation |
Spectinamides as anti-tuberculosis agents
|
|
RU2012108849A
(ru)
*
|
2009-08-10 |
2013-09-20 |
П2-Сайенс Апс |
Utp для диагностирования стеноза и других состояний ограниченного кровотока
|
|
JP5922111B2
(ja)
*
|
2010-06-23 |
2016-05-24 |
ピーツー−サイエンス・エペイエス |
充血剤注入と同時に血圧測定を行う診断目的の動脈用複合カテーテル
|
|
WO2012030645A1
(en)
|
2010-08-30 |
2012-03-08 |
Pulmatrix, Inc. |
Respirably dry powder comprising calcium lactate, sodium chloride and leucine
|
|
CN103200938B
(zh)
|
2010-08-30 |
2018-07-31 |
普马特里克斯营业公司 |
干燥粉末配方及用于治疗肺部疾病的方法
|
|
BR112013007304B1
(pt)
|
2010-09-29 |
2021-12-14 |
Pulmatrix, Inc. |
Pós secos de cátion de metal monovalente para inalação
|
|
PT3470057T
(pt)
|
2010-09-29 |
2021-12-03 |
Pulmatrix Operating Co Inc |
Pós secos catiónicos compreendendo sais de magnésio
|
|
WO2012068381A2
(en)
|
2010-11-17 |
2012-05-24 |
The University Of North Carolina At Chapel Hill |
Protection of renal tissues from schema through inhibition of the proliferative kisses cdk4 and cdk6
|
|
US8945605B2
(en)
|
2011-06-07 |
2015-02-03 |
Parion Sciences, Inc. |
Aerosol delivery systems, compositions and methods
|
|
US8778383B2
(en)
|
2011-06-07 |
2014-07-15 |
Parion Sciences, Inc. |
Methods of treatment
|
|
AR086745A1
(es)
|
2011-06-27 |
2014-01-22 |
Parion Sciences Inc |
3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
|
|
CN107596518B
(zh)
|
2012-02-29 |
2021-04-23 |
普马特里克斯营业公司 |
可吸入干粉剂
|
|
US9833207B2
(en)
|
2012-08-08 |
2017-12-05 |
William Harrison Zurn |
Analysis and clearing module, system and method
|
|
RU2018138195A
(ru)
|
2012-12-17 |
2018-12-18 |
Пэрион Сайенсиз, Инк. |
Соединения 3,5-диамино-6-хлор-n-(n-(4- фенилбутил)карбамимидоил)пиразин-2-карбоксамида
|
|
SG10201708931XA
(en)
|
2012-12-17 |
2017-12-28 |
Parion Sciences Inc |
Chloro-pyrazine carboxamide derivatives useful for the treatment of diseases favoured by insufficient mucosal hydration
|
|
US9962533B2
(en)
|
2013-02-14 |
2018-05-08 |
William Harrison Zurn |
Module for treatment of medical conditions; system for making module and methods of making module
|
|
ME03557B
(me)
|
2013-03-15 |
2020-07-20 |
G1 Therapeutics Inc |
Privremena zaštiтa normalnih ćelija током hemoterapije
|
|
CA2906157C
(en)
|
2013-03-15 |
2022-05-17 |
G1 Therapeutics, Inc. |
Highly active anti-neoplastic and anti-proliferative agents
|
|
AU2014248455B2
(en)
|
2013-04-01 |
2018-12-06 |
Pulmatrix Operating Company, Inc. |
Tiotropium dry powders
|
|
CN105592851A
(zh)
|
2013-09-30 |
2016-05-18 |
帕西昂Api服务公司 |
利用复分解反应的前列腺素和前列腺素中间体的新合成途径
|
|
US9102633B2
(en)
|
2013-12-13 |
2015-08-11 |
Parion Sciences, Inc. |
Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds
|
|
WO2015161288A1
(en)
|
2014-04-17 |
2015-10-22 |
G1 Therapeutics, Inc. |
Tricyclic lactams for use as anti-neoplastic and anti-proliferative agents
|
|
WO2016040848A1
(en)
|
2014-09-12 |
2016-03-17 |
G1 Therapeutics, Inc. |
Treatment of rb-negative tumors using topoisomerase inhibitors in combination with cyclin dependent kinase 4/6 inhibitors
|
|
EP3191098A4
(en)
|
2014-09-12 |
2018-04-25 |
G1 Therapeutics, Inc. |
Combinations and dosing regimes to treat rb-positive tumors
|
|
CN104306028B
(zh)
*
|
2014-09-26 |
2016-08-17 |
张清玲 |
一种用于呼吸道细菌16S rRNA基因序列检测的痰液收集方法
|
|
WO2017035401A1
(en)
|
2015-08-26 |
2017-03-02 |
Achillion Pharmaceuticals, Inc. |
Amide compounds for treatment of immune and inflammatory disorders
|
|
WO2017035409A1
(en)
|
2015-08-26 |
2017-03-02 |
Achillion Pharmaceuticals, Inc. |
Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders
|
|
WO2017035405A1
(en)
|
2015-08-26 |
2017-03-02 |
Achillion Pharmaceuticals, Inc. |
Amino compounds for treatment of immune and inflammatory disorders
|
|
AR106018A1
(es)
|
2015-08-26 |
2017-12-06 |
Achillion Pharmaceuticals Inc |
Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
|
|
WO2017139381A1
(en)
|
2016-02-08 |
2017-08-17 |
University Of Iowa Research Foundation |
Methods to produce chimeric adeno-associated virus/bocavirus parvovirus
|
|
CA3016985C
(en)
|
2016-03-07 |
2023-07-04 |
University Of Iowa Research Foundation |
Aav-mediated expression using a synthetic promoter and enhancer
|
|
WO2017205739A1
(en)
|
2016-05-26 |
2017-11-30 |
University Of Iowa Research Foundation |
cis AND trans REQUIREMENTS FOR TERMINAL RESOLUTION OF HUMAN BOCAVIRUS 1
|
|
RU2019102647A
(ru)
|
2016-07-01 |
2020-08-03 |
Г1 Терапьютикс, Инк. |
Антипролиферационные средства на основе пиримидина
|
|
US10413583B2
(en)
|
2016-11-30 |
2019-09-17 |
The University Of Chicago |
Synthetic substrates for enzymes that catalyze reactions of modified cysteines and related methods
|
|
US11142775B2
(en)
|
2017-01-13 |
2021-10-12 |
University Of Iowa Research Foundation |
Bocaparvovirus small noncoding RNA and uses thereof
|
|
WO2018160891A1
(en)
|
2017-03-01 |
2018-09-07 |
Achillion Pharmaceutical, Inc. |
Pharmaceutical compounds for treatment of medical disorders
|
|
CN110603252A
(zh)
|
2017-03-01 |
2019-12-20 |
艾其林医药公司 |
用于治疗医学障碍的芳基、杂芳基和杂环药物化合物
|
|
EP3661493A4
(en)
|
2017-08-02 |
2021-04-14 |
Achillion Pharmaceuticals, Inc. |
THERAPY PLANS FOR TREATMENT OF PAROXYSMALER NIGHTLY HEMOGLOBINURIA
|
|
GB2604314A
(en)
|
2017-09-22 |
2022-09-07 |
Nerudia Ltd |
Device, system and method
|
|
US11439608B2
(en)
|
2017-09-25 |
2022-09-13 |
Qun Lu |
Roles of modulators of intersectin-CDC42 signaling in Alzheimer's disease
|
|
WO2019113210A1
(en)
|
2017-12-05 |
2019-06-13 |
Anthos Partners, Lp |
Phosphonium-based ionic drug conjugates
|
|
JP7443375B2
(ja)
|
2018-09-06 |
2024-03-05 |
アキリオン ファーマシューティカルズ, インコーポレーテッド |
医学的障害の治療のための大環状化合物
|
|
WO2020051538A1
(en)
|
2018-09-06 |
2020-03-12 |
Achillion Pharmaceuticals, Inc. |
Morphic forms of complement factor d inhibitors
|
|
KR20210093855A
(ko)
|
2018-09-25 |
2021-07-28 |
아칠리온 파르마세우티칼스 인코포레이티드 |
보체 인자 d 억제제의 형태체 형태
|
|
WO2020131974A1
(en)
|
2018-12-17 |
2020-06-25 |
Achillion Pharmaceuticals, Inc. |
Targeted dosing for the treatment of complement mediated disorders
|
|
BR112021018456A2
(pt)
|
2019-03-22 |
2021-11-23 |
Achillion Pharmaceuticals Inc |
Compostos farmacêuticos para o tratamento de distúrbios mediados por complemento
|
|
KR20230012547A
(ko)
|
2020-05-19 |
2023-01-26 |
쥐원 쎄라퓨틱스, 인크. |
의학적 장애의 치료를 위한 시클린-의존성 키나제 억제 화합물
|
|
US10988479B1
(en)
|
2020-06-15 |
2021-04-27 |
G1 Therapeutics, Inc. |
Morphic forms of trilaciclib and methods of manufacture thereof
|