KR100283306B1 - 폐질환의검출방법 - Google Patents
폐질환의검출방법 Download PDFInfo
- Publication number
- KR100283306B1 KR100283306B1 KR1019980700675A KR19980700675A KR100283306B1 KR 100283306 B1 KR100283306 B1 KR 100283306B1 KR 1019980700675 A KR1019980700675 A KR 1019980700675A KR 19980700675 A KR19980700675 A KR 19980700675A KR 100283306 B1 KR100283306 B1 KR 100283306B1
- Authority
- KR
- South Korea
- Prior art keywords
- composition
- compound
- formula
- acceptable salt
- effective amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Otolaryngology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/509,052 US5628984A (en) | 1995-07-31 | 1995-07-31 | Method of detecting lung disease |
| US8/509052 | 1995-07-31 | ||
| PCT/US1996/012377 WO1997005195A1 (en) | 1995-07-31 | 1996-07-24 | Method of detecting lung disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR19990036011A KR19990036011A (ko) | 1999-05-25 |
| KR100283306B1 true KR100283306B1 (ko) | 2001-03-02 |
Family
ID=24025091
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019980700675A Expired - Fee Related KR100283306B1 (ko) | 1995-07-31 | 1996-07-24 | 폐질환의검출방법 |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US5628984A (enExample) |
| EP (1) | EP0841900B1 (enExample) |
| JP (2) | JP3623237B2 (enExample) |
| KR (1) | KR100283306B1 (enExample) |
| CN (1) | CN1121441C (enExample) |
| AT (1) | ATE276740T1 (enExample) |
| AU (1) | AU705528B2 (enExample) |
| BR (1) | BR9610059A (enExample) |
| CA (1) | CA2226892A1 (enExample) |
| DE (1) | DE69633449T2 (enExample) |
| ES (1) | ES2229281T3 (enExample) |
| IL (1) | IL122803A0 (enExample) |
| MX (1) | MX9800933A (enExample) |
| NO (1) | NO980279D0 (enExample) |
| NZ (1) | NZ313864A (enExample) |
| WO (1) | WO1997005195A1 (enExample) |
| ZA (1) | ZA966425B (enExample) |
Families Citing this family (106)
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| US5628984A (en) * | 1995-07-31 | 1997-05-13 | University Of North Carolina At Chapel Hill | Method of detecting lung disease |
| US5968913A (en) * | 1996-07-03 | 1999-10-19 | Inspire Pharmaceuticals, Inc. | Pharmaceutical compositions of uridine triphosphate |
| US6319908B1 (en) | 1996-07-03 | 2001-11-20 | Inspire Pharmaceuticals, Inc. | Method for large-scale production of di(uridine 5′-tetraphosphate) and salts thereof |
| US5763447C1 (en) | 1996-07-23 | 2002-05-07 | Inspire Pharmaceuticals | Method of preventing or treating pneumonia in immobilized patients with uridine triphosphates and related compounds |
| US6159952A (en) * | 1996-11-07 | 2000-12-12 | Inspire Pharmaceuticals, Inc. | Method of treating bronchitis with uridine triphosphate and related compounds |
| US6998121B2 (en) | 2003-01-23 | 2006-02-14 | Milkhaus Laboratory, Inc. | Method of treatment of connective tissue disorders by administration of streptolysin O |
| CA2295515C (en) | 1997-07-25 | 2006-03-14 | Inspire Pharmaceuticals, Inc. | Method for large-scale production of di(uridine 5'-tetraphosphate) and salts thereof |
| TW593331B (en) | 1997-07-25 | 2004-06-21 | Inspire Pharmaceuticals Inc | Method for large-scale production of di(uridine 5')-tetraphosphate and salts thereof |
| US6872710B2 (en) * | 1997-07-25 | 2005-03-29 | Inspire Pharmaceuticals, Inc. | Di(uridine 5′)-tetraphosphate and salts thereof |
| CA2300146A1 (en) * | 1997-08-29 | 1999-03-04 | Richard C. Boucher, Jr. | Use of uridine 5'-diphosphate and analogs thereof for the treatment of lung diseases |
| US6926911B1 (en) * | 1998-12-22 | 2005-08-09 | The University Of North Carolina At Chapel Hill | Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs |
| EP1139746A4 (en) * | 1998-12-22 | 2003-09-17 | Univ North Carolina | CONNECTIONS AND METHODS FOR THE TREATMENT OF RESPIRATORY DISEASES AND THE ADMINISTRATION OF MEDICINAL SUBSTANCES |
| MXPA01008547A (es) * | 1999-02-26 | 2003-06-06 | Inspire Pharmaceuticals Inc | Metodo para promover la hidratacion de mucosas con ciertos difosfatos de uridina, adenina y citidina, y analogos de estos. |
| JP4969002B2 (ja) * | 1999-06-08 | 2012-07-04 | ユニバーシテイ・オブ・アイオワ・リサーチ・フアウンデーシヨン | rAAV形質導入を増加するための化合物および方法 |
| US7241447B1 (en) * | 1999-10-07 | 2007-07-10 | University Of Iowa Research Foundation | Adeno-associated virus vectors and uses thereof |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5292498A (en) * | 1991-06-19 | 1994-03-08 | The University Of North Carolina At Chapel Hill | Method of treating lung disease with uridine triphosphates |
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| FR2571257A1 (fr) * | 1984-08-06 | 1986-04-11 | Gros Pierre | Composition destinee a l'humidification de la muqueuse rhino-pharyngee |
| US5470838A (en) * | 1987-10-28 | 1995-11-28 | Pro-Neuron, Inc. | Method of delivering exogenous uridine or cytidine using acylated uridine or cytidine |
| US4950477A (en) * | 1988-08-23 | 1990-08-21 | Memorial Hospital For Cancer And Allied Dieseas | Method of preventing and treating pulmonary infection by fungi using aerosolized polyenes |
| GB9027968D0 (en) * | 1990-12-22 | 1991-02-13 | Fisons Plc | Method of treatment |
| EP0517573A1 (fr) * | 1991-06-05 | 1992-12-09 | Synthelabo | Compositions pharmaceutiques pour le traitement des affections des voies respiratoires |
| US5567689A (en) * | 1993-08-13 | 1996-10-22 | The Uab Research Foundation | Methods for increasing uridine levels with L-nucleosides |
| US5656256A (en) * | 1994-12-14 | 1997-08-12 | The University Of North Carolina At Chapel Hill | Methods of treating lung disease by an aerosol containing benzamil or phenamil |
| US5628984A (en) * | 1995-07-31 | 1997-05-13 | University Of North Carolina At Chapel Hill | Method of detecting lung disease |
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1995
- 1995-07-31 US US08/509,052 patent/US5628984A/en not_active Expired - Lifetime
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1996
- 1996-07-24 IL IL12280396A patent/IL122803A0/xx unknown
- 1996-07-24 CN CN96195803A patent/CN1121441C/zh not_active Expired - Fee Related
- 1996-07-24 DE DE69633449T patent/DE69633449T2/de not_active Expired - Fee Related
- 1996-07-24 US US08/776,772 patent/US6133247A/en not_active Expired - Lifetime
- 1996-07-24 KR KR1019980700675A patent/KR100283306B1/ko not_active Expired - Fee Related
- 1996-07-24 BR BR9610059A patent/BR9610059A/pt not_active Application Discontinuation
- 1996-07-24 AU AU66399/96A patent/AU705528B2/en not_active Ceased
- 1996-07-24 EP EP96926158A patent/EP0841900B1/en not_active Expired - Lifetime
- 1996-07-24 CA CA002226892A patent/CA2226892A1/en not_active Abandoned
- 1996-07-24 JP JP50781797A patent/JP3623237B2/ja not_active Expired - Fee Related
- 1996-07-24 MX MX9800933A patent/MX9800933A/es not_active IP Right Cessation
- 1996-07-24 NZ NZ313864A patent/NZ313864A/xx unknown
- 1996-07-24 AT AT96926158T patent/ATE276740T1/de not_active IP Right Cessation
- 1996-07-24 WO PCT/US1996/012377 patent/WO1997005195A1/en not_active Ceased
- 1996-07-24 ES ES96926158T patent/ES2229281T3/es not_active Expired - Lifetime
- 1996-07-29 ZA ZA9606425A patent/ZA966425B/xx unknown
- 1996-12-30 US US08/777,026 patent/US5902567A/en not_active Expired - Lifetime
-
1998
- 1998-01-21 NO NO980279A patent/NO980279D0/no not_active Application Discontinuation
-
1999
- 1999-11-04 US US09/433,757 patent/US6214536B1/en not_active Expired - Lifetime
-
2002
- 2002-08-05 JP JP2002227140A patent/JP2003073280A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5292498A (en) * | 1991-06-19 | 1994-03-08 | The University Of North Carolina At Chapel Hill | Method of treating lung disease with uridine triphosphates |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003073280A (ja) | 2003-03-12 |
| EP0841900A4 (enExample) | 1998-06-10 |
| ES2229281T3 (es) | 2005-04-16 |
| CN1191553A (zh) | 1998-08-26 |
| DE69633449T2 (de) | 2006-04-27 |
| US5628984A (en) | 1997-05-13 |
| US6214536B1 (en) | 2001-04-10 |
| JPH11509759A (ja) | 1999-08-31 |
| WO1997005195A1 (en) | 1997-02-13 |
| AU6639996A (en) | 1997-02-26 |
| ZA966425B (en) | 1997-02-19 |
| ATE276740T1 (de) | 2004-10-15 |
| CN1121441C (zh) | 2003-09-17 |
| NO980279L (no) | 1998-01-21 |
| BR9610059A (pt) | 1999-03-02 |
| MX9800933A (es) | 1998-05-31 |
| IL122803A0 (en) | 1998-09-16 |
| AU705528B2 (en) | 1999-05-27 |
| JP3623237B2 (ja) | 2005-02-23 |
| CA2226892A1 (en) | 1997-02-13 |
| US5902567A (en) | 1999-05-11 |
| NZ313864A (en) | 2000-04-28 |
| NO980279D0 (no) | 1998-01-21 |
| DE69633449D1 (de) | 2004-10-28 |
| US6133247A (en) | 2000-10-17 |
| EP0841900B1 (en) | 2004-09-22 |
| EP0841900A1 (en) | 1998-05-20 |
| KR19990036011A (ko) | 1999-05-25 |
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