ATE275287T1 - Massenspektrometrieverfahren unter benutzung eines kerbfilters - Google Patents
Massenspektrometrieverfahren unter benutzung eines kerbfiltersInfo
- Publication number
- ATE275287T1 ATE275287T1 AT92907342T AT92907342T ATE275287T1 AT E275287 T1 ATE275287 T1 AT E275287T1 AT 92907342 T AT92907342 T AT 92907342T AT 92907342 T AT92907342 T AT 92907342T AT E275287 T1 ATE275287 T1 AT E275287T1
- Authority
- AT
- Austria
- Prior art keywords
- ions
- filtered noise
- trapping field
- trapping
- detector
- Prior art date
Links
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
- H01J49/4205—Device types
- H01J49/424—Three-dimensional ion traps, i.e. comprising end-cap and ring electrodes
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
- H01J49/0081—Tandem in time, i.e. using a single spectrometer
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
- H01J49/426—Methods for controlling ions
- H01J49/427—Ejection and selection methods
- H01J49/428—Applying a notched broadband signal
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Electron Tubes For Measurement (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Filtering Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/662,217 US5134286A (en) | 1991-02-28 | 1991-02-28 | Mass spectrometry method using notch filter |
PCT/US1992/001109 WO1992016009A1 (en) | 1991-02-28 | 1992-02-11 | Mass spectrometry method using notch filter |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE275287T1 true ATE275287T1 (de) | 2004-09-15 |
Family
ID=24656855
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT92907342T ATE275287T1 (de) | 1991-02-28 | 1992-02-11 | Massenspektrometrieverfahren unter benutzung eines kerbfilters |
Country Status (7)
Country | Link |
---|---|
US (3) | US5134286A (de) |
EP (1) | EP0573556B1 (de) |
JP (1) | JP3010740B2 (de) |
AT (1) | ATE275287T1 (de) |
CA (1) | CA2101427C (de) |
DE (1) | DE69233406T2 (de) |
WO (1) | WO1992016009A1 (de) |
Families Citing this family (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5200613A (en) * | 1991-02-28 | 1993-04-06 | Teledyne Mec | Mass spectrometry method using supplemental AC voltage signals |
US5206507A (en) * | 1991-02-28 | 1993-04-27 | Teledyne Mec | Mass spectrometry method using filtered noise signal |
US5381007A (en) * | 1991-02-28 | 1995-01-10 | Teledyne Mec A Division Of Teledyne Industries, Inc. | Mass spectrometry method with two applied trapping fields having same spatial form |
US5256875A (en) * | 1992-05-14 | 1993-10-26 | Teledyne Mec | Method for generating filtered noise signal and broadband signal having reduced dynamic range for use in mass spectrometry |
US5449905A (en) * | 1992-05-14 | 1995-09-12 | Teledyne Et | Method for generating filtered noise signal and broadband signal having reduced dynamic range for use in mass spectrometry |
US5187365A (en) * | 1991-02-28 | 1993-02-16 | Teledyne Mec | Mass spectrometry method using time-varying filtered noise |
US5436445A (en) * | 1991-02-28 | 1995-07-25 | Teledyne Electronic Technologies | Mass spectrometry method with two applied trapping fields having same spatial form |
US5134286A (en) * | 1991-02-28 | 1992-07-28 | Teledyne Cme | Mass spectrometry method using notch filter |
US5451782A (en) * | 1991-02-28 | 1995-09-19 | Teledyne Et | Mass spectometry method with applied signal having off-resonance frequency |
US5198665A (en) * | 1992-05-29 | 1993-03-30 | Varian Associates, Inc. | Quadrupole trap improved technique for ion isolation |
US5397894A (en) * | 1993-05-28 | 1995-03-14 | Varian Associates, Inc. | Method of high mass resolution scanning of an ion trap mass spectrometer |
US5457315A (en) * | 1994-01-11 | 1995-10-10 | Varian Associates, Inc. | Method of selective ion trapping for quadrupole ion trap mass spectrometers |
DE4316737C1 (de) * | 1993-05-19 | 1994-09-01 | Bruker Franzen Analytik Gmbh | Verfahren zur digitalen Erzeugung einer zusätzlichen Wechselspannung für die resonante Anregung von Ionen in Ionenfallen |
US5324939A (en) * | 1993-05-28 | 1994-06-28 | Finnigan Corporation | Method and apparatus for ejecting unwanted ions in an ion trap mass spectrometer |
DE4324233C1 (de) * | 1993-07-20 | 1995-01-19 | Bruker Franzen Analytik Gmbh | Verfahren zur Auswahl der Reaktionspfade in Ionenfallen |
US6011259A (en) * | 1995-08-10 | 2000-01-04 | Analytica Of Branford, Inc. | Multipole ion guide ion trap mass spectrometry with MS/MSN analysis |
US8610056B2 (en) | 1994-02-28 | 2013-12-17 | Perkinelmer Health Sciences Inc. | Multipole ion guide ion trap mass spectrometry with MS/MSn analysis |
DK0748249T3 (da) | 1994-02-28 | 2009-11-09 | Analytica Of Branford Inc | Multipolionguide for massespektrometri |
US5531353A (en) * | 1994-10-26 | 1996-07-02 | Ward; Ronald K. | Drinking cup device |
DE19501835C2 (de) * | 1995-01-21 | 1998-07-02 | Bruker Franzen Analytik Gmbh | Verfahren zur Anregung der Schwingungen von Ionen in Ionenfallen mit Frequenzgemischen |
DE19501823A1 (de) * | 1995-01-21 | 1996-07-25 | Bruker Franzen Analytik Gmbh | Verfahren zur Regelung der Erzeugungsraten für massenselektives Einspeichern von Ionen in Ionenfallen |
JP3509267B2 (ja) * | 1995-04-03 | 2004-03-22 | 株式会社日立製作所 | イオントラップ質量分析方法および装置 |
JPH095298A (ja) * | 1995-06-06 | 1997-01-10 | Varian Assoc Inc | 四重極イオントラップ内の選択イオン種を検出する方法 |
US8847157B2 (en) | 1995-08-10 | 2014-09-30 | Perkinelmer Health Sciences, Inc. | Multipole ion guide ion trap mass spectrometry with MS/MSn analysis |
US5672870A (en) * | 1995-12-18 | 1997-09-30 | Hewlett Packard Company | Mass selective notch filter with quadrupole excision fields |
US5598001A (en) * | 1996-01-30 | 1997-01-28 | Hewlett-Packard Company | Mass selective multinotch filter with orthogonal excision fields |
US5696376A (en) * | 1996-05-20 | 1997-12-09 | The Johns Hopkins University | Method and apparatus for isolating ions in an ion trap with increased resolving power |
US5793038A (en) * | 1996-12-10 | 1998-08-11 | Varian Associates, Inc. | Method of operating an ion trap mass spectrometer |
US6140638A (en) * | 1997-06-04 | 2000-10-31 | Mds Inc. | Bandpass reactive collision cell |
GB9820210D0 (en) | 1998-09-16 | 1998-11-11 | Vg Elemental Limited | Means for removing unwanted ions from an ion transport system and mass spectrometer |
GB9924722D0 (en) | 1999-10-19 | 1999-12-22 | Shimadzu Res Lab Europe Ltd | Methods and apparatus for driving a quadrupole device |
AU2066501A (en) * | 1999-12-06 | 2001-06-12 | Dmi Biosciences, Inc. | Noise reducing/resolution enhancing signal processing method and system |
JP3625265B2 (ja) | 1999-12-07 | 2005-03-02 | 株式会社日立製作所 | イオントラップ型質量分析装置 |
US6787767B2 (en) | 2001-11-07 | 2004-09-07 | Hitachi High-Technologies Corporation | Mass analyzing method using an ion trap type mass spectrometer |
US6710336B2 (en) | 2002-01-30 | 2004-03-23 | Varian, Inc. | Ion trap mass spectrometer using pre-calculated waveforms for ion isolation and collision induced dissociation |
JP3951741B2 (ja) * | 2002-02-27 | 2007-08-01 | 株式会社日立製作所 | 電荷調整方法とその装置、および質量分析装置 |
GB0210930D0 (en) | 2002-05-13 | 2002-06-19 | Thermo Electron Corp | Improved mass spectrometer and mass filters therefor |
JP3791455B2 (ja) * | 2002-05-20 | 2006-06-28 | 株式会社島津製作所 | イオントラップ型質量分析装置 |
US6838665B2 (en) * | 2002-09-26 | 2005-01-04 | Hitachi High-Technologies Corporation | Ion trap type mass spectrometer |
US6680476B1 (en) * | 2002-11-22 | 2004-01-20 | Agilent Technologies, Inc. | Summed time-of-flight mass spectrometry utilizing thresholding to reduce noise |
WO2005116378A2 (en) * | 2004-05-24 | 2005-12-08 | University Of Massachusetts | Multiplexed tandem mass spectrometry |
US7772549B2 (en) | 2004-05-24 | 2010-08-10 | University Of Massachusetts | Multiplexed tandem mass spectrometry |
US7456396B2 (en) * | 2004-08-19 | 2008-11-25 | Thermo Finnigan Llc | Isolating ions in quadrupole ion traps for mass spectrometry |
GB0425426D0 (en) * | 2004-11-18 | 2004-12-22 | Micromass Ltd | Mass spectrometer |
US8334503B2 (en) | 2005-05-09 | 2012-12-18 | Purdue Research Foundation | Parallel ion parking in ion traps |
DE102005025497B4 (de) * | 2005-06-03 | 2007-09-27 | Bruker Daltonik Gmbh | Leichte Bruckstückionen mit Ionenfallen messen |
GB0511386D0 (en) * | 2005-06-03 | 2005-07-13 | Shimadzu Res Lab Europe Ltd | Method for introducing ions into an ion trap and an ion storage apparatus |
GB0513047D0 (en) * | 2005-06-27 | 2005-08-03 | Thermo Finnigan Llc | Electronic ion trap |
US7378648B2 (en) * | 2005-09-30 | 2008-05-27 | Varian, Inc. | High-resolution ion isolation utilizing broadband waveform signals |
US7378653B2 (en) * | 2006-01-10 | 2008-05-27 | Varian, Inc. | Increasing ion kinetic energy along axis of linear ion processing devices |
US7405399B2 (en) * | 2006-01-30 | 2008-07-29 | Varian, Inc. | Field conditions for ion excitation in linear ion processing apparatus |
US7405400B2 (en) * | 2006-01-30 | 2008-07-29 | Varian, Inc. | Adjusting field conditions in linear ion processing apparatus for different modes of operation |
US7351965B2 (en) * | 2006-01-30 | 2008-04-01 | Varian, Inc. | Rotating excitation field in linear ion processing apparatus |
GB0701476D0 (en) * | 2007-01-25 | 2007-03-07 | Micromass Ltd | Mass spectrometer |
US7656236B2 (en) | 2007-05-15 | 2010-02-02 | Teledyne Wireless, Llc | Noise canceling technique for frequency synthesizer |
US8334506B2 (en) | 2007-12-10 | 2012-12-18 | 1St Detect Corporation | End cap voltage control of ion traps |
US8179045B2 (en) | 2008-04-22 | 2012-05-15 | Teledyne Wireless, Llc | Slow wave structure having offset projections comprised of a metal-dielectric composite stack |
US7973277B2 (en) | 2008-05-27 | 2011-07-05 | 1St Detect Corporation | Driving a mass spectrometer ion trap or mass filter |
GB0900973D0 (en) | 2009-01-21 | 2009-03-04 | Micromass Ltd | Method and apparatus for performing MS^N |
US8178835B2 (en) * | 2009-05-07 | 2012-05-15 | Thermo Finnigan Llc | Prolonged ion resonance collision induced dissociation in a quadrupole ion trap |
JP5440449B2 (ja) | 2010-08-30 | 2014-03-12 | 株式会社島津製作所 | イオントラップ質量分析装置 |
EP2894654B1 (de) | 2012-09-10 | 2019-05-08 | Shimadzu Corporation | Ionenauswahlverfahren in einer ionenfalle und ionenfalle |
GB201302785D0 (en) * | 2013-02-18 | 2013-04-03 | Micromass Ltd | Device allowing improved reaction monitoring of gas phase reactions in mass spectrometers using an auto ejection ion trap |
US9653279B2 (en) | 2013-02-18 | 2017-05-16 | Micromass Uk Limited | Device allowing improved reaction monitoring of gas phase reactions in mass spectrometers using an auto ejection ion trap |
US20150380231A1 (en) * | 2013-02-18 | 2015-12-31 | Micromass Uk Limited | Improved Efficiency and Precise Control of Gas Phase Reactions in Mass Spectrometers Using an Auto Ejection Ion Trap |
US9202660B2 (en) | 2013-03-13 | 2015-12-01 | Teledyne Wireless, Llc | Asymmetrical slow wave structures to eliminate backward wave oscillations in wideband traveling wave tubes |
US9818595B2 (en) | 2015-05-11 | 2017-11-14 | Thermo Finnigan Llc | Systems and methods for ion isolation using a dual waveform |
US9875885B2 (en) | 2015-05-11 | 2018-01-23 | Thermo Finnigan Llc | Systems and methods for ion isolation |
EP3321953B1 (de) | 2016-11-10 | 2019-06-26 | Thermo Finnigan LLC | Systeme und verfahren zur skalierung einer injektion-wellenformsamplitude während der ionenisolation |
GB2584334B (en) * | 2019-05-31 | 2022-02-16 | Owlstone Med Ltd | Sensor system |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT528250A (de) * | 1953-12-24 | |||
US3334225A (en) * | 1964-04-24 | 1967-08-01 | California Inst Res Found | Quadrupole mass filter with means to generate a noise spectrum exclusive of the resonant frequency of the desired ions to deflect stable ions |
US4540884A (en) * | 1982-12-29 | 1985-09-10 | Finnigan Corporation | Method of mass analyzing a sample by use of a quadrupole ion trap |
US4650999A (en) * | 1984-10-22 | 1987-03-17 | Finnigan Corporation | Method of mass analyzing a sample over a wide mass range by use of a quadrupole ion trap |
DE3650304T2 (de) * | 1985-05-24 | 1995-10-12 | Finnigan Corp | Betriebsverfahren für eine Ionenfalle. |
US4686367A (en) * | 1985-09-06 | 1987-08-11 | Finnigan Corporation | Method of operating quadrupole ion trap chemical ionization mass spectrometry |
US4761545A (en) * | 1986-05-23 | 1988-08-02 | The Ohio State University Research Foundation | Tailored excitation for trapped ion mass spectrometry |
US4749860A (en) * | 1986-06-05 | 1988-06-07 | Finnigan Corporation | Method of isolating a single mass in a quadrupole ion trap |
US4755670A (en) * | 1986-10-01 | 1988-07-05 | Finnigan Corporation | Fourtier transform quadrupole mass spectrometer and method |
US4818869A (en) * | 1987-05-22 | 1989-04-04 | Finnigan Corporation | Method of isolating a single mass or narrow range of masses and/or enhancing the sensitivity of an ion trap mass spectrometer |
US4771172A (en) * | 1987-05-22 | 1988-09-13 | Finnigan Corporation | Method of increasing the dynamic range and sensitivity of a quadrupole ion trap mass spectrometer operating in the chemical ionization mode |
EP0336990B1 (de) * | 1988-04-13 | 1994-01-05 | Bruker Franzen Analytik GmbH | Methode zur Massenanalyse einer Probe mittels eines Quistors und zur Durchführung dieses Verfahrens entwickelter Quistor |
EP0362432A1 (de) * | 1988-10-07 | 1990-04-11 | Bruker Franzen Analytik GmbH | Methode zur Massenanalyse einer Probe |
DE68913290T2 (de) * | 1989-02-18 | 1994-05-26 | Bruker Franzen Analytik Gmbh | Verfahren und Gerät zur Massenbestimmung von Proben mittels eines Quistors. |
US5206507A (en) * | 1991-02-28 | 1993-04-27 | Teledyne Mec | Mass spectrometry method using filtered noise signal |
US5187365A (en) * | 1991-02-28 | 1993-02-16 | Teledyne Mec | Mass spectrometry method using time-varying filtered noise |
US5196699A (en) * | 1991-02-28 | 1993-03-23 | Teledyne Mec | Chemical ionization mass spectrometry method using notch filter |
US5134286A (en) * | 1991-02-28 | 1992-07-28 | Teledyne Cme | Mass spectrometry method using notch filter |
US5256875A (en) * | 1992-05-14 | 1993-10-26 | Teledyne Mec | Method for generating filtered noise signal and broadband signal having reduced dynamic range for use in mass spectrometry |
US5200613A (en) * | 1991-02-28 | 1993-04-06 | Teledyne Mec | Mass spectrometry method using supplemental AC voltage signals |
US5105081A (en) * | 1991-02-28 | 1992-04-14 | Teledyne Cme | Mass spectrometry method and apparatus employing in-trap ion detection |
-
1991
- 1991-02-28 US US07/662,217 patent/US5134286A/en not_active Expired - Lifetime
-
1992
- 1992-02-11 WO PCT/US1992/001109 patent/WO1992016009A1/en active IP Right Grant
- 1992-02-11 JP JP4507044A patent/JP3010740B2/ja not_active Expired - Lifetime
- 1992-02-11 AT AT92907342T patent/ATE275287T1/de not_active IP Right Cessation
- 1992-02-11 EP EP92907342A patent/EP0573556B1/de not_active Expired - Lifetime
- 1992-02-11 CA CA002101427A patent/CA2101427C/en not_active Expired - Lifetime
- 1992-02-11 DE DE69233406T patent/DE69233406T2/de not_active Expired - Lifetime
-
1993
- 1993-07-12 US US08/090,474 patent/US5345078A/en not_active Expired - Lifetime
-
1994
- 1994-08-30 US US08/298,388 patent/US5466931A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5345078A (en) | 1994-09-06 |
EP0573556B1 (de) | 2004-09-01 |
WO1992016009A1 (en) | 1992-09-17 |
CA2101427A1 (en) | 1992-08-29 |
CA2101427C (en) | 1998-12-01 |
EP0573556A4 (en) | 1995-08-23 |
US5466931A (en) | 1995-11-14 |
DE69233406D1 (de) | 2004-10-07 |
JPH06505826A (ja) | 1994-06-30 |
US5134286A (en) | 1992-07-28 |
JP3010740B2 (ja) | 2000-02-21 |
EP0573556A1 (de) | 1993-12-15 |
DE69233406T2 (de) | 2005-03-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69233406D1 (de) | Massenspektrometrieverfahren unter benutzung eines kerbfilters | |
DE69232866D1 (de) | Chemisches ionisationsmassenspektrometrieverfahren mit einem kerbfilter | |
US6713757B2 (en) | Controlling the temporal response of mass spectrometers for mass spectrometry | |
Koppenaal et al. | Performance of an inductively coupled plasma source ion trap mass spectrometer | |
US5179278A (en) | Multipole inlet system for ion traps | |
CA2430512C (en) | Method for improving signal-to-noise ratios for atmospheric pressure ionization mass spectrometry | |
Williams et al. | Resonance ejection ion trap mass spectrometry and nonlinear field contributions: the effect of scan direction on mass resolution | |
AU2002238327A1 (en) | Controlling the temporal response of mass spectrometers for mass spectrometry | |
WO2009153841A1 (ja) | 質量分析装置 | |
CA2312754C (en) | Method of and apparatus for selective collision-induced dissociation of ions in a quadrupole ion guide | |
EP0868730B1 (de) | Verfahren zum auffangen von ionen in ionenfallen und ionenfalle-massenspektrometersystem | |
US5750993A (en) | Method of reducing noise in an ion trap mass spectrometer coupled to an atmospheric pressure ionization source | |
US5187365A (en) | Mass spectrometry method using time-varying filtered noise | |
JP5749018B2 (ja) | 低圧力短時間高振幅励起を提供するために線形イオントラップを動作する方法 | |
US20220254618A1 (en) | RF Ion Trap Ion Loading Method | |
CA2166207A1 (en) | Quadrupole with applied signal having off-resonance frequency | |
US5331157A (en) | Method of clean removal of ions | |
JP4417524B2 (ja) | 誘導結合プラズマ質量分析装置 | |
RU2003108091A (ru) | Способ разделения изотопов таллия в электромагнитном сепараторе |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |