ATE275287T1 - Massenspektrometrieverfahren unter benutzung eines kerbfilters - Google Patents

Massenspektrometrieverfahren unter benutzung eines kerbfilters

Info

Publication number
ATE275287T1
ATE275287T1 AT92907342T AT92907342T ATE275287T1 AT E275287 T1 ATE275287 T1 AT E275287T1 AT 92907342 T AT92907342 T AT 92907342T AT 92907342 T AT92907342 T AT 92907342T AT E275287 T1 ATE275287 T1 AT E275287T1
Authority
AT
Austria
Prior art keywords
ions
filtered noise
trapping field
trapping
detector
Prior art date
Application number
AT92907342T
Other languages
English (en)
Inventor
Paul E Kelley
Original Assignee
Shimadzu Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shimadzu Corp filed Critical Shimadzu Corp
Application granted granted Critical
Publication of ATE275287T1 publication Critical patent/ATE275287T1/de

Links

Classifications

    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205Device types
    • H01J49/424Three-dimensional ion traps, i.e. comprising end-cap and ring electrodes
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/004Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0081Tandem in time, i.e. using a single spectrometer
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/426Methods for controlling ions
    • H01J49/427Ejection and selection methods
    • H01J49/428Applying a notched broadband signal

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Electron Tubes For Measurement (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Filtering Materials (AREA)
AT92907342T 1991-02-28 1992-02-11 Massenspektrometrieverfahren unter benutzung eines kerbfilters ATE275287T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/662,217 US5134286A (en) 1991-02-28 1991-02-28 Mass spectrometry method using notch filter
PCT/US1992/001109 WO1992016009A1 (en) 1991-02-28 1992-02-11 Mass spectrometry method using notch filter

Publications (1)

Publication Number Publication Date
ATE275287T1 true ATE275287T1 (de) 2004-09-15

Family

ID=24656855

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92907342T ATE275287T1 (de) 1991-02-28 1992-02-11 Massenspektrometrieverfahren unter benutzung eines kerbfilters

Country Status (7)

Country Link
US (3) US5134286A (de)
EP (1) EP0573556B1 (de)
JP (1) JP3010740B2 (de)
AT (1) ATE275287T1 (de)
CA (1) CA2101427C (de)
DE (1) DE69233406T2 (de)
WO (1) WO1992016009A1 (de)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5200613A (en) * 1991-02-28 1993-04-06 Teledyne Mec Mass spectrometry method using supplemental AC voltage signals
US5206507A (en) * 1991-02-28 1993-04-27 Teledyne Mec Mass spectrometry method using filtered noise signal
US5381007A (en) * 1991-02-28 1995-01-10 Teledyne Mec A Division Of Teledyne Industries, Inc. Mass spectrometry method with two applied trapping fields having same spatial form
US5256875A (en) * 1992-05-14 1993-10-26 Teledyne Mec Method for generating filtered noise signal and broadband signal having reduced dynamic range for use in mass spectrometry
US5449905A (en) * 1992-05-14 1995-09-12 Teledyne Et Method for generating filtered noise signal and broadband signal having reduced dynamic range for use in mass spectrometry
US5187365A (en) * 1991-02-28 1993-02-16 Teledyne Mec Mass spectrometry method using time-varying filtered noise
US5436445A (en) * 1991-02-28 1995-07-25 Teledyne Electronic Technologies Mass spectrometry method with two applied trapping fields having same spatial form
US5134286A (en) * 1991-02-28 1992-07-28 Teledyne Cme Mass spectrometry method using notch filter
US5451782A (en) * 1991-02-28 1995-09-19 Teledyne Et Mass spectometry method with applied signal having off-resonance frequency
US5198665A (en) * 1992-05-29 1993-03-30 Varian Associates, Inc. Quadrupole trap improved technique for ion isolation
US5397894A (en) * 1993-05-28 1995-03-14 Varian Associates, Inc. Method of high mass resolution scanning of an ion trap mass spectrometer
US5457315A (en) * 1994-01-11 1995-10-10 Varian Associates, Inc. Method of selective ion trapping for quadrupole ion trap mass spectrometers
DE4316737C1 (de) * 1993-05-19 1994-09-01 Bruker Franzen Analytik Gmbh Verfahren zur digitalen Erzeugung einer zusätzlichen Wechselspannung für die resonante Anregung von Ionen in Ionenfallen
US5324939A (en) * 1993-05-28 1994-06-28 Finnigan Corporation Method and apparatus for ejecting unwanted ions in an ion trap mass spectrometer
DE4324233C1 (de) * 1993-07-20 1995-01-19 Bruker Franzen Analytik Gmbh Verfahren zur Auswahl der Reaktionspfade in Ionenfallen
US6011259A (en) * 1995-08-10 2000-01-04 Analytica Of Branford, Inc. Multipole ion guide ion trap mass spectrometry with MS/MSN analysis
US8610056B2 (en) 1994-02-28 2013-12-17 Perkinelmer Health Sciences Inc. Multipole ion guide ion trap mass spectrometry with MS/MSn analysis
DK0748249T3 (da) 1994-02-28 2009-11-09 Analytica Of Branford Inc Multipolionguide for massespektrometri
US5531353A (en) * 1994-10-26 1996-07-02 Ward; Ronald K. Drinking cup device
DE19501835C2 (de) * 1995-01-21 1998-07-02 Bruker Franzen Analytik Gmbh Verfahren zur Anregung der Schwingungen von Ionen in Ionenfallen mit Frequenzgemischen
DE19501823A1 (de) * 1995-01-21 1996-07-25 Bruker Franzen Analytik Gmbh Verfahren zur Regelung der Erzeugungsraten für massenselektives Einspeichern von Ionen in Ionenfallen
JP3509267B2 (ja) * 1995-04-03 2004-03-22 株式会社日立製作所 イオントラップ質量分析方法および装置
JPH095298A (ja) * 1995-06-06 1997-01-10 Varian Assoc Inc 四重極イオントラップ内の選択イオン種を検出する方法
US8847157B2 (en) 1995-08-10 2014-09-30 Perkinelmer Health Sciences, Inc. Multipole ion guide ion trap mass spectrometry with MS/MSn analysis
US5672870A (en) * 1995-12-18 1997-09-30 Hewlett Packard Company Mass selective notch filter with quadrupole excision fields
US5598001A (en) * 1996-01-30 1997-01-28 Hewlett-Packard Company Mass selective multinotch filter with orthogonal excision fields
US5696376A (en) * 1996-05-20 1997-12-09 The Johns Hopkins University Method and apparatus for isolating ions in an ion trap with increased resolving power
US5793038A (en) * 1996-12-10 1998-08-11 Varian Associates, Inc. Method of operating an ion trap mass spectrometer
US6140638A (en) * 1997-06-04 2000-10-31 Mds Inc. Bandpass reactive collision cell
GB9820210D0 (en) 1998-09-16 1998-11-11 Vg Elemental Limited Means for removing unwanted ions from an ion transport system and mass spectrometer
GB9924722D0 (en) 1999-10-19 1999-12-22 Shimadzu Res Lab Europe Ltd Methods and apparatus for driving a quadrupole device
AU2066501A (en) * 1999-12-06 2001-06-12 Dmi Biosciences, Inc. Noise reducing/resolution enhancing signal processing method and system
JP3625265B2 (ja) 1999-12-07 2005-03-02 株式会社日立製作所 イオントラップ型質量分析装置
US6787767B2 (en) 2001-11-07 2004-09-07 Hitachi High-Technologies Corporation Mass analyzing method using an ion trap type mass spectrometer
US6710336B2 (en) 2002-01-30 2004-03-23 Varian, Inc. Ion trap mass spectrometer using pre-calculated waveforms for ion isolation and collision induced dissociation
JP3951741B2 (ja) * 2002-02-27 2007-08-01 株式会社日立製作所 電荷調整方法とその装置、および質量分析装置
GB0210930D0 (en) 2002-05-13 2002-06-19 Thermo Electron Corp Improved mass spectrometer and mass filters therefor
JP3791455B2 (ja) * 2002-05-20 2006-06-28 株式会社島津製作所 イオントラップ型質量分析装置
US6838665B2 (en) * 2002-09-26 2005-01-04 Hitachi High-Technologies Corporation Ion trap type mass spectrometer
US6680476B1 (en) * 2002-11-22 2004-01-20 Agilent Technologies, Inc. Summed time-of-flight mass spectrometry utilizing thresholding to reduce noise
WO2005116378A2 (en) * 2004-05-24 2005-12-08 University Of Massachusetts Multiplexed tandem mass spectrometry
US7772549B2 (en) 2004-05-24 2010-08-10 University Of Massachusetts Multiplexed tandem mass spectrometry
US7456396B2 (en) * 2004-08-19 2008-11-25 Thermo Finnigan Llc Isolating ions in quadrupole ion traps for mass spectrometry
GB0425426D0 (en) * 2004-11-18 2004-12-22 Micromass Ltd Mass spectrometer
US8334503B2 (en) 2005-05-09 2012-12-18 Purdue Research Foundation Parallel ion parking in ion traps
DE102005025497B4 (de) * 2005-06-03 2007-09-27 Bruker Daltonik Gmbh Leichte Bruckstückionen mit Ionenfallen messen
GB0511386D0 (en) * 2005-06-03 2005-07-13 Shimadzu Res Lab Europe Ltd Method for introducing ions into an ion trap and an ion storage apparatus
GB0513047D0 (en) * 2005-06-27 2005-08-03 Thermo Finnigan Llc Electronic ion trap
US7378648B2 (en) * 2005-09-30 2008-05-27 Varian, Inc. High-resolution ion isolation utilizing broadband waveform signals
US7378653B2 (en) * 2006-01-10 2008-05-27 Varian, Inc. Increasing ion kinetic energy along axis of linear ion processing devices
US7405399B2 (en) * 2006-01-30 2008-07-29 Varian, Inc. Field conditions for ion excitation in linear ion processing apparatus
US7405400B2 (en) * 2006-01-30 2008-07-29 Varian, Inc. Adjusting field conditions in linear ion processing apparatus for different modes of operation
US7351965B2 (en) * 2006-01-30 2008-04-01 Varian, Inc. Rotating excitation field in linear ion processing apparatus
GB0701476D0 (en) * 2007-01-25 2007-03-07 Micromass Ltd Mass spectrometer
US7656236B2 (en) 2007-05-15 2010-02-02 Teledyne Wireless, Llc Noise canceling technique for frequency synthesizer
US8334506B2 (en) 2007-12-10 2012-12-18 1St Detect Corporation End cap voltage control of ion traps
US8179045B2 (en) 2008-04-22 2012-05-15 Teledyne Wireless, Llc Slow wave structure having offset projections comprised of a metal-dielectric composite stack
US7973277B2 (en) 2008-05-27 2011-07-05 1St Detect Corporation Driving a mass spectrometer ion trap or mass filter
GB0900973D0 (en) 2009-01-21 2009-03-04 Micromass Ltd Method and apparatus for performing MS^N
US8178835B2 (en) * 2009-05-07 2012-05-15 Thermo Finnigan Llc Prolonged ion resonance collision induced dissociation in a quadrupole ion trap
JP5440449B2 (ja) 2010-08-30 2014-03-12 株式会社島津製作所 イオントラップ質量分析装置
EP2894654B1 (de) 2012-09-10 2019-05-08 Shimadzu Corporation Ionenauswahlverfahren in einer ionenfalle und ionenfalle
GB201302785D0 (en) * 2013-02-18 2013-04-03 Micromass Ltd Device allowing improved reaction monitoring of gas phase reactions in mass spectrometers using an auto ejection ion trap
US9653279B2 (en) 2013-02-18 2017-05-16 Micromass Uk Limited Device allowing improved reaction monitoring of gas phase reactions in mass spectrometers using an auto ejection ion trap
US20150380231A1 (en) * 2013-02-18 2015-12-31 Micromass Uk Limited Improved Efficiency and Precise Control of Gas Phase Reactions in Mass Spectrometers Using an Auto Ejection Ion Trap
US9202660B2 (en) 2013-03-13 2015-12-01 Teledyne Wireless, Llc Asymmetrical slow wave structures to eliminate backward wave oscillations in wideband traveling wave tubes
US9818595B2 (en) 2015-05-11 2017-11-14 Thermo Finnigan Llc Systems and methods for ion isolation using a dual waveform
US9875885B2 (en) 2015-05-11 2018-01-23 Thermo Finnigan Llc Systems and methods for ion isolation
EP3321953B1 (de) 2016-11-10 2019-06-26 Thermo Finnigan LLC Systeme und verfahren zur skalierung einer injektion-wellenformsamplitude während der ionenisolation
GB2584334B (en) * 2019-05-31 2022-02-16 Owlstone Med Ltd Sensor system

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT528250A (de) * 1953-12-24
US3334225A (en) * 1964-04-24 1967-08-01 California Inst Res Found Quadrupole mass filter with means to generate a noise spectrum exclusive of the resonant frequency of the desired ions to deflect stable ions
US4540884A (en) * 1982-12-29 1985-09-10 Finnigan Corporation Method of mass analyzing a sample by use of a quadrupole ion trap
US4650999A (en) * 1984-10-22 1987-03-17 Finnigan Corporation Method of mass analyzing a sample over a wide mass range by use of a quadrupole ion trap
DE3650304T2 (de) * 1985-05-24 1995-10-12 Finnigan Corp Betriebsverfahren für eine Ionenfalle.
US4686367A (en) * 1985-09-06 1987-08-11 Finnigan Corporation Method of operating quadrupole ion trap chemical ionization mass spectrometry
US4761545A (en) * 1986-05-23 1988-08-02 The Ohio State University Research Foundation Tailored excitation for trapped ion mass spectrometry
US4749860A (en) * 1986-06-05 1988-06-07 Finnigan Corporation Method of isolating a single mass in a quadrupole ion trap
US4755670A (en) * 1986-10-01 1988-07-05 Finnigan Corporation Fourtier transform quadrupole mass spectrometer and method
US4818869A (en) * 1987-05-22 1989-04-04 Finnigan Corporation Method of isolating a single mass or narrow range of masses and/or enhancing the sensitivity of an ion trap mass spectrometer
US4771172A (en) * 1987-05-22 1988-09-13 Finnigan Corporation Method of increasing the dynamic range and sensitivity of a quadrupole ion trap mass spectrometer operating in the chemical ionization mode
EP0336990B1 (de) * 1988-04-13 1994-01-05 Bruker Franzen Analytik GmbH Methode zur Massenanalyse einer Probe mittels eines Quistors und zur Durchführung dieses Verfahrens entwickelter Quistor
EP0362432A1 (de) * 1988-10-07 1990-04-11 Bruker Franzen Analytik GmbH Methode zur Massenanalyse einer Probe
DE68913290T2 (de) * 1989-02-18 1994-05-26 Bruker Franzen Analytik Gmbh Verfahren und Gerät zur Massenbestimmung von Proben mittels eines Quistors.
US5206507A (en) * 1991-02-28 1993-04-27 Teledyne Mec Mass spectrometry method using filtered noise signal
US5187365A (en) * 1991-02-28 1993-02-16 Teledyne Mec Mass spectrometry method using time-varying filtered noise
US5196699A (en) * 1991-02-28 1993-03-23 Teledyne Mec Chemical ionization mass spectrometry method using notch filter
US5134286A (en) * 1991-02-28 1992-07-28 Teledyne Cme Mass spectrometry method using notch filter
US5256875A (en) * 1992-05-14 1993-10-26 Teledyne Mec Method for generating filtered noise signal and broadband signal having reduced dynamic range for use in mass spectrometry
US5200613A (en) * 1991-02-28 1993-04-06 Teledyne Mec Mass spectrometry method using supplemental AC voltage signals
US5105081A (en) * 1991-02-28 1992-04-14 Teledyne Cme Mass spectrometry method and apparatus employing in-trap ion detection

Also Published As

Publication number Publication date
US5345078A (en) 1994-09-06
EP0573556B1 (de) 2004-09-01
WO1992016009A1 (en) 1992-09-17
CA2101427A1 (en) 1992-08-29
CA2101427C (en) 1998-12-01
EP0573556A4 (en) 1995-08-23
US5466931A (en) 1995-11-14
DE69233406D1 (de) 2004-10-07
JPH06505826A (ja) 1994-06-30
US5134286A (en) 1992-07-28
JP3010740B2 (ja) 2000-02-21
EP0573556A1 (de) 1993-12-15
DE69233406T2 (de) 2005-03-03

Similar Documents

Publication Publication Date Title
DE69233406D1 (de) Massenspektrometrieverfahren unter benutzung eines kerbfilters
DE69232866D1 (de) Chemisches ionisationsmassenspektrometrieverfahren mit einem kerbfilter
US6713757B2 (en) Controlling the temporal response of mass spectrometers for mass spectrometry
Koppenaal et al. Performance of an inductively coupled plasma source ion trap mass spectrometer
US5179278A (en) Multipole inlet system for ion traps
CA2430512C (en) Method for improving signal-to-noise ratios for atmospheric pressure ionization mass spectrometry
Williams et al. Resonance ejection ion trap mass spectrometry and nonlinear field contributions: the effect of scan direction on mass resolution
AU2002238327A1 (en) Controlling the temporal response of mass spectrometers for mass spectrometry
WO2009153841A1 (ja) 質量分析装置
CA2312754C (en) Method of and apparatus for selective collision-induced dissociation of ions in a quadrupole ion guide
EP0868730B1 (de) Verfahren zum auffangen von ionen in ionenfallen und ionenfalle-massenspektrometersystem
US5750993A (en) Method of reducing noise in an ion trap mass spectrometer coupled to an atmospheric pressure ionization source
US5187365A (en) Mass spectrometry method using time-varying filtered noise
JP5749018B2 (ja) 低圧力短時間高振幅励起を提供するために線形イオントラップを動作する方法
US20220254618A1 (en) RF Ion Trap Ion Loading Method
CA2166207A1 (en) Quadrupole with applied signal having off-resonance frequency
US5331157A (en) Method of clean removal of ions
JP4417524B2 (ja) 誘導結合プラズマ質量分析装置
RU2003108091A (ru) Способ разделения изотопов таллия в электромагнитном сепараторе

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties