ATE268382T1 - MENSCHLICHE-ßCDR-GRAFTEDß-ANTIKÖRPER GEGEN GANGLIOSID GM2 - Google Patents
MENSCHLICHE-ßCDR-GRAFTEDß-ANTIKÖRPER GEGEN GANGLIOSID GM2Info
- Publication number
- ATE268382T1 ATE268382T1 AT98105047T AT98105047T ATE268382T1 AT E268382 T1 ATE268382 T1 AT E268382T1 AT 98105047 T AT98105047 T AT 98105047T AT 98105047 T AT98105047 T AT 98105047T AT E268382 T1 ATE268382 T1 AT E268382T1
- Authority
- AT
- Austria
- Prior art keywords
- cdr
- seq
- human
- chain
- ßcdr
- Prior art date
Links
- GIVLTTJNORAZON-HDBOBKCLSA-N ganglioside GM2 (18:0) Chemical compound O[C@@H]1[C@@H](O)[C@H](OC[C@H](NC(=O)CCCCCCCCCCCCCCCCC)[C@H](O)\C=C\CCCCCCCCCCCCC)O[C@H](CO)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@]2(O[C@H]([C@H](NC(C)=O)[C@@H](O)C2)[C@H](O)[C@H](O)CO)C(O)=O)[C@@H](O[C@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](CO)O1 GIVLTTJNORAZON-HDBOBKCLSA-N 0.000 title abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 3
- 108091035707 Consensus sequence Proteins 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP06698197A JP4550947B2 (ja) | 1997-03-19 | 1997-03-19 | ガングリオシドｇｍ２に対するヒト型相補性決定領域（ｃｄｒ）移植抗体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE268382T1 true ATE268382T1 (de) | 2004-06-15 |
Family
ID=13331716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98105047T ATE268382T1 (de) | 1997-03-19 | 1998-03-19 | MENSCHLICHE-ßCDR-GRAFTEDß-ANTIKÖRPER GEGEN GANGLIOSID GM2 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0882794B1 (enExample) |
| JP (1) | JP4550947B2 (enExample) |
| AT (1) | ATE268382T1 (enExample) |
| AU (1) | AU751948B2 (enExample) |
| CA (1) | CA2226400C (enExample) |
| DE (1) | DE69824234T2 (enExample) |
| ES (1) | ES2219802T3 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6407734B1 (en) | 1994-10-31 | 2002-06-18 | Nec-Mitsubishi Electric Visual Systems Corporation | Power supply system capable of reducing power consumption during interruption of an external input signal given to an operating circuit |
| US7241568B2 (en) | 1996-04-03 | 2007-07-10 | Kyowa Hakko Kogyo Co., Ltd. | Anti-fibroblast growth factor-8 monoclonal antibody |
| PT1914244E (pt) | 1999-04-09 | 2013-07-26 | Kyowa Hakko Kirin Co Ltd | Processo para regular a actividade de moléculas funcionais sob o ponto de vista imunológico |
| US6693176B1 (en) | 1999-07-23 | 2004-02-17 | University Of Massachusetts | Antitumor antibodies, proteins, and uses thereof |
| AU7449200A (en) * | 1999-09-30 | 2001-04-30 | Kyowa Hakko Kogyo Co. Ltd. | Derivatives of antibody against ganglioside gm2 |
| FR2807767B1 (fr) * | 2000-04-12 | 2005-01-14 | Lab Francais Du Fractionnement | Anticorps monoclonaux anti-d |
| AU2016204535C1 (en) * | 2000-04-12 | 2017-02-23 | Laboratoire Français Du Fractionnement Et Des Biotechnologies | Anti-D monoclonal antibodies |
| JP2001299349A (ja) * | 2000-04-19 | 2001-10-30 | Suntory Ltd | 新規組換え型抗体とそのｃｄｒのアミノ酸配列およびそれをコードする遺伝子 |
| WO2002031140A1 (en) * | 2000-10-06 | 2002-04-18 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions |
| US6946292B2 (en) | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
| ES2303859T3 (es) | 2001-06-28 | 2008-09-01 | Kyowa Hakko Kogyo Co., Ltd | Anticuerpo humanizado contra el factor de crecimiento fibroblastico 8 y fragmento del anticuerpo. |
| US7935338B2 (en) | 2001-12-11 | 2011-05-03 | University Of Massachusetts | Antibodies to treat cancer |
| WO2003057251A1 (fr) * | 2001-12-28 | 2003-07-17 | Kyowa Hakko Kogyo Co., Ltd. | Remedes contre l'arthrite |
| JPWO2003084569A1 (ja) | 2002-04-09 | 2005-08-11 | 協和醗酵工業株式会社 | 抗体組成物含有医薬 |
| US20040115204A1 (en) | 2002-12-11 | 2004-06-17 | Fanger Gary R. | Antibodies to treat cancer |
| US7691810B2 (en) | 2003-10-09 | 2010-04-06 | Kyowa Hakko Kirin Co., Ltd | Method of producing recombinant antithrombin III composition |
| JPWO2005035578A1 (ja) * | 2003-10-09 | 2007-11-22 | 協和醗酵工業株式会社 | ガングリオシドｇｍ２に特異的に結合する抗体組成物 |
| EP2107115A1 (en) | 2007-01-24 | 2009-10-07 | Kyowa Hakko Kirin Co., Ltd. | Genetically recombinant antibody composition capable of binding specifically to ganglioside gm2 |
| FR2953841B1 (fr) * | 2009-12-16 | 2011-12-30 | Centre Nat Rech Scient | Anticorps diriges contre le recepteur de la transferrine et leurs utilisations pour l'immunotherapie des tumeurs qui dependent du fer |
| KR101913440B1 (ko) | 2010-03-02 | 2018-10-30 | 교와 핫꼬 기린 가부시키가이샤 | 개변 항체 조성물 |
| KR20150090107A (ko) | 2012-12-06 | 2015-08-05 | 도쿠리츠다이가쿠호징 가나자와다이가쿠 | 중피종의 치료 방법 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69333524T2 (de) * | 1992-09-07 | 2005-06-16 | Kyowa Hakko Kogyo Co., Ltd. | Humanisierte Antikörper, die mit dem GM2-Gangliosid reagieren |
-
1997
- 1997-03-19 JP JP06698197A patent/JP4550947B2/ja not_active Expired - Lifetime
-
1998
- 1998-03-19 AT AT98105047T patent/ATE268382T1/de not_active IP Right Cessation
- 1998-03-19 ES ES98105047T patent/ES2219802T3/es not_active Expired - Lifetime
- 1998-03-19 DE DE69824234T patent/DE69824234T2/de not_active Expired - Lifetime
- 1998-03-19 EP EP98105047A patent/EP0882794B1/en not_active Expired - Lifetime
- 1998-03-19 CA CA002226400A patent/CA2226400C/en not_active Expired - Lifetime
- 1998-03-19 AU AU59420/98A patent/AU751948B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JP4550947B2 (ja) | 2010-09-22 |
| ES2219802T3 (es) | 2004-12-01 |
| JPH10257893A (ja) | 1998-09-29 |
| EP0882794A3 (en) | 1999-06-16 |
| DE69824234D1 (de) | 2004-07-08 |
| EP0882794B1 (en) | 2004-06-02 |
| AU5942098A (en) | 1998-10-01 |
| CA2226400A1 (en) | 1998-09-19 |
| CA2226400C (en) | 2008-12-02 |
| EP0882794A2 (en) | 1998-12-09 |
| DE69824234T2 (de) | 2005-06-23 |
| AU751948B2 (en) | 2002-09-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |