JP4550947B2 - ガングリオシドgm2に対するヒト型相補性決定領域(cdr)移植抗体 - Google Patents
ガングリオシドgm2に対するヒト型相補性決定領域(cdr)移植抗体 Download PDFInfo
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- JP4550947B2 JP4550947B2 JP06698197A JP6698197A JP4550947B2 JP 4550947 B2 JP4550947 B2 JP 4550947B2 JP 06698197 A JP06698197 A JP 06698197A JP 6698197 A JP6698197 A JP 6698197A JP 4550947 B2 JP4550947 B2 JP 4550947B2
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
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Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP06698197A JP4550947B2 (ja) | 1997-03-19 | 1997-03-19 | ガングリオシドgm2に対するヒト型相補性決定領域(cdr)移植抗体 |
| AT98105047T ATE268382T1 (de) | 1997-03-19 | 1998-03-19 | MENSCHLICHE-ßCDR-GRAFTEDß-ANTIKÖRPER GEGEN GANGLIOSID GM2 |
| AU59420/98A AU751948B2 (en) | 1997-03-19 | 1998-03-19 | Human complementarity determining region (CDR)-grafted antibody to ganglioside GM2 |
| EP98105047A EP0882794B1 (en) | 1997-03-19 | 1998-03-19 | Human complementarity determining region (CDR)-grafted antibody to ganglioside gm2 |
| DE69824234T DE69824234T2 (de) | 1997-03-19 | 1998-03-19 | Menschliche"CDR-grafted"-Antikörper gegen Gangliosid GM2 |
| CA002226400A CA2226400C (en) | 1997-03-19 | 1998-03-19 | Human complementarity determining region (cdr) - grafted antibody to ganglioside gm2 |
| ES98105047T ES2219802T3 (es) | 1997-03-19 | 1998-03-19 | Anticuerpo contra el glangliosido gm2, injertado en la zona de determinacion de complementariedad humana (cdr). |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP06698197A JP4550947B2 (ja) | 1997-03-19 | 1997-03-19 | ガングリオシドgm2に対するヒト型相補性決定領域(cdr)移植抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPH10257893A JPH10257893A (ja) | 1998-09-29 |
| JPH10257893A5 JPH10257893A5 (enExample) | 2005-02-24 |
| JP4550947B2 true JP4550947B2 (ja) | 2010-09-22 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP06698197A Expired - Lifetime JP4550947B2 (ja) | 1997-03-19 | 1997-03-19 | ガングリオシドgm2に対するヒト型相補性決定領域(cdr)移植抗体 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0882794B1 (enExample) |
| JP (1) | JP4550947B2 (enExample) |
| AT (1) | ATE268382T1 (enExample) |
| AU (1) | AU751948B2 (enExample) |
| CA (1) | CA2226400C (enExample) |
| DE (1) | DE69824234T2 (enExample) |
| ES (1) | ES2219802T3 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014088040A1 (ja) | 2012-12-06 | 2014-06-12 | 国立大学法人 金沢大学 | 中皮腫の治療方法 |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6407734B1 (en) | 1994-10-31 | 2002-06-18 | Nec-Mitsubishi Electric Visual Systems Corporation | Power supply system capable of reducing power consumption during interruption of an external input signal given to an operating circuit |
| US7241568B2 (en) | 1996-04-03 | 2007-07-10 | Kyowa Hakko Kogyo Co., Ltd. | Anti-fibroblast growth factor-8 monoclonal antibody |
| PT1914244E (pt) | 1999-04-09 | 2013-07-26 | Kyowa Hakko Kirin Co Ltd | Processo para regular a actividade de moléculas funcionais sob o ponto de vista imunológico |
| US6693176B1 (en) | 1999-07-23 | 2004-02-17 | University Of Massachusetts | Antitumor antibodies, proteins, and uses thereof |
| AU7449200A (en) * | 1999-09-30 | 2001-04-30 | Kyowa Hakko Kogyo Co. Ltd. | Derivatives of antibody against ganglioside gm2 |
| FR2807767B1 (fr) * | 2000-04-12 | 2005-01-14 | Lab Francais Du Fractionnement | Anticorps monoclonaux anti-d |
| AU2016204535C1 (en) * | 2000-04-12 | 2017-02-23 | Laboratoire Français Du Fractionnement Et Des Biotechnologies | Anti-D monoclonal antibodies |
| JP2001299349A (ja) * | 2000-04-19 | 2001-10-30 | Suntory Ltd | 新規組換え型抗体とそのcdrのアミノ酸配列およびそれをコードする遺伝子 |
| WO2002031140A1 (en) * | 2000-10-06 | 2002-04-18 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions |
| US6946292B2 (en) | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
| ES2303859T3 (es) | 2001-06-28 | 2008-09-01 | Kyowa Hakko Kogyo Co., Ltd | Anticuerpo humanizado contra el factor de crecimiento fibroblastico 8 y fragmento del anticuerpo. |
| US7935338B2 (en) | 2001-12-11 | 2011-05-03 | University Of Massachusetts | Antibodies to treat cancer |
| WO2003057251A1 (fr) * | 2001-12-28 | 2003-07-17 | Kyowa Hakko Kogyo Co., Ltd. | Remedes contre l'arthrite |
| JPWO2003084569A1 (ja) | 2002-04-09 | 2005-08-11 | 協和醗酵工業株式会社 | 抗体組成物含有医薬 |
| US20040115204A1 (en) | 2002-12-11 | 2004-06-17 | Fanger Gary R. | Antibodies to treat cancer |
| US7691810B2 (en) | 2003-10-09 | 2010-04-06 | Kyowa Hakko Kirin Co., Ltd | Method of producing recombinant antithrombin III composition |
| JPWO2005035578A1 (ja) * | 2003-10-09 | 2007-11-22 | 協和醗酵工業株式会社 | ガングリオシドgm2に特異的に結合する抗体組成物 |
| EP2107115A1 (en) | 2007-01-24 | 2009-10-07 | Kyowa Hakko Kirin Co., Ltd. | Genetically recombinant antibody composition capable of binding specifically to ganglioside gm2 |
| FR2953841B1 (fr) * | 2009-12-16 | 2011-12-30 | Centre Nat Rech Scient | Anticorps diriges contre le recepteur de la transferrine et leurs utilisations pour l'immunotherapie des tumeurs qui dependent du fer |
| KR101913440B1 (ko) | 2010-03-02 | 2018-10-30 | 교와 핫꼬 기린 가부시키가이샤 | 개변 항체 조성물 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69333524T2 (de) * | 1992-09-07 | 2005-06-16 | Kyowa Hakko Kogyo Co., Ltd. | Humanisierte Antikörper, die mit dem GM2-Gangliosid reagieren |
-
1997
- 1997-03-19 JP JP06698197A patent/JP4550947B2/ja not_active Expired - Lifetime
-
1998
- 1998-03-19 AT AT98105047T patent/ATE268382T1/de not_active IP Right Cessation
- 1998-03-19 ES ES98105047T patent/ES2219802T3/es not_active Expired - Lifetime
- 1998-03-19 DE DE69824234T patent/DE69824234T2/de not_active Expired - Lifetime
- 1998-03-19 EP EP98105047A patent/EP0882794B1/en not_active Expired - Lifetime
- 1998-03-19 CA CA002226400A patent/CA2226400C/en not_active Expired - Lifetime
- 1998-03-19 AU AU59420/98A patent/AU751948B2/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014088040A1 (ja) | 2012-12-06 | 2014-06-12 | 国立大学法人 金沢大学 | 中皮腫の治療方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| ATE268382T1 (de) | 2004-06-15 |
| ES2219802T3 (es) | 2004-12-01 |
| JPH10257893A (ja) | 1998-09-29 |
| EP0882794A3 (en) | 1999-06-16 |
| DE69824234D1 (de) | 2004-07-08 |
| EP0882794B1 (en) | 2004-06-02 |
| AU5942098A (en) | 1998-10-01 |
| CA2226400A1 (en) | 1998-09-19 |
| CA2226400C (en) | 2008-12-02 |
| EP0882794A2 (en) | 1998-12-09 |
| DE69824234T2 (de) | 2005-06-23 |
| AU751948B2 (en) | 2002-09-05 |
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