US6670127B2
(en)
|
1997-09-16 |
2003-12-30 |
Egea Biosciences, Inc. |
Method for assembly of a polynucleotide encoding a target polypeptide
|
WO2000053617A1
(en)
*
|
1999-03-08 |
2000-09-14 |
Protogene Laboratories, Inc. |
Methods and compositions for economically synthesizing and assembling long dna sequences
|
ATE415409T1
(de)
|
1999-05-24 |
2008-12-15 |
Invitrogen Corp |
Ein verfahren zum entschützen markierter oligonukleotide
|
AU1279901A
(en)
*
|
1999-11-05 |
2001-05-14 |
Biomade B.V. |
Methods for the preparation of (lipo)peptide synthetases and (lipo)peptides produced therewith
|
US20020009728A1
(en)
*
|
2000-01-18 |
2002-01-24 |
Quantum Dot Corporation |
Oligonucleotide-tagged semiconductor nanocrystals for microarray and fluorescence in situ hybridization
|
JP2001204463A
(ja)
*
|
2000-01-27 |
2001-07-31 |
Toyo Kohan Co Ltd |
ヌクレオチド固定用担体
|
US6579680B2
(en)
*
|
2000-02-28 |
2003-06-17 |
Corning Incorporated |
Method for label-free detection of hybridized DNA targets
|
US20040009514A1
(en)
*
|
2000-02-28 |
2004-01-15 |
Frutos Anthony G. |
Assembly for label-free detection of hybridized nucleic targets
|
US6368801B1
(en)
|
2000-04-12 |
2002-04-09 |
Molecular Staging, Inc. |
Detection and amplification of RNA using target-mediated ligation of DNA by RNA ligase
|
US6479262B1
(en)
|
2000-05-16 |
2002-11-12 |
Hercules, Incorporated |
Solid phase enzymatic assembly of polynucleotides
|
WO2001094366A1
(en)
|
2000-06-02 |
2001-12-13 |
Blue Heron Biotechnology, Inc. |
Methods for improving the sequence fidelity of synthetic double-stranded oligonucleotides
|
EP1205548A1
(de)
*
|
2000-11-09 |
2002-05-15 |
Kabushiki Kaisha Toyota Chuo Kenkyusho |
Verfahren und Vorrichtung zur Festphasen-Ligation von Doppelsträngige DNA-Molekülen
|
JP4516273B2
(ja)
*
|
2000-11-15 |
2010-08-04 |
ミナーヴァ・バイオテクノロジーズ・コーポレーション |
オリゴヌクレオチド識別子
|
GB0031093D0
(en)
*
|
2000-12-20 |
2001-01-31 |
Birkbeck College |
Materials and methods for nucleic acid systhesis
|
DE10104025B4
(de)
*
|
2001-01-31 |
2008-07-10 |
Qiagen North American Holdings, Inc. |
Verfahren zur Aufreinigung und anschließenden Amplifikation von Doppelstrang-DNA
|
US20030049619A1
(en)
*
|
2001-03-21 |
2003-03-13 |
Simon Delagrave |
Methods for the synthesis of polynucleotides and combinatorial libraries of polynucleotides
|
US7164992B1
(en)
|
2001-03-22 |
2007-01-16 |
Blue Heron Biotechnology, Inc. |
Method and system for polynucleotide synthesis
|
US7727713B2
(en)
|
2001-06-20 |
2010-06-01 |
Nuevolution A/S |
Templated molecules and methods for using such molecules
|
US7238477B2
(en)
*
|
2001-09-24 |
2007-07-03 |
Intel Corporation |
Methods to increase nucleotide signals by Raman scattering
|
US6972173B2
(en)
*
|
2002-03-14 |
2005-12-06 |
Intel Corporation |
Methods to increase nucleotide signals by raman scattering
|
WO2003040342A2
(en)
*
|
2001-11-07 |
2003-05-15 |
Integrigen, Inc. |
Method for generation of modular polynucleotides using solid supports
|
US20110151438A9
(en)
*
|
2001-11-19 |
2011-06-23 |
Affymetrix, Inc. |
Methods of Analysis of Methylation
|
US6696254B2
(en)
*
|
2001-11-21 |
2004-02-24 |
Kimberly-Clark Worldwide, Inc. |
Detection and identification of enteric bacteria
|
US20030148284A1
(en)
*
|
2001-12-17 |
2003-08-07 |
Vision Todd J. |
Solid phase detection of nucleic acid molecules
|
AU2003207448A1
(en)
*
|
2002-01-04 |
2003-07-24 |
Board Of Regents, The University Of Texas System |
Proofreading, error deletion, and ligation method for synthesis of high-fidelity polynucleotide sequences
|
DE50213541D1
(de)
*
|
2002-01-11 |
2009-06-25 |
Biospring Ges Fuer Biotechnolo |
Verfahren zur Herstellung von DNA
|
EP1487978B1
(de)
|
2002-03-15 |
2008-11-19 |
Nuevolution A/S |
Eine verbesserte methode zur synthese von matritzenabhängigen molekülen
|
US20030186301A1
(en)
*
|
2002-03-25 |
2003-10-02 |
The Regents Of The University Of California |
Constructing user-defined, long DNA sequences
|
AU2003230736A1
(en)
*
|
2002-03-25 |
2004-07-29 |
Datascope Investment Corp. |
Nucleic acid hybridization assay using bridging sequence
|
US7482119B2
(en)
*
|
2002-04-01 |
2009-01-27 |
Blue Heron Biotechnology, Inc. |
Solid phase methods for polynucleotide production
|
US20030228602A1
(en)
*
|
2002-04-01 |
2003-12-11 |
Blue Heron Biotechnology, Inc. |
Solid phase methods for polynucleotide production
|
AU2003243562A1
(en)
*
|
2002-06-12 |
2003-12-31 |
Datascope Investment Corp. |
Polymeric label molecules
|
US10730906B2
(en)
*
|
2002-08-01 |
2020-08-04 |
Nuevolutions A/S |
Multi-step synthesis of templated molecules
|
US7563600B2
(en)
|
2002-09-12 |
2009-07-21 |
Combimatrix Corporation |
Microarray synthesis and assembly of gene-length polynucleotides
|
WO2004028682A2
(en)
*
|
2002-09-27 |
2004-04-08 |
Carlsberg A/S |
Spatially encoded polymer matrix
|
CN106337046B
(zh)
*
|
2002-10-30 |
2021-03-23 |
纽韦卢森公司 |
合成双功能复合物的方法
|
US20040086895A1
(en)
*
|
2002-11-06 |
2004-05-06 |
Crothers Donald M. |
Method of electrochemical detection of somatic cell mutations
|
US7090979B2
(en)
*
|
2002-11-22 |
2006-08-15 |
The Regents Of The University Of California |
Derivatized versions of ligase enzymes for constructing DNA sequences
|
WO2004056994A2
(en)
|
2002-12-19 |
2004-07-08 |
Nuevolution A/S |
Quasirandom structure and function guided synthesis methods
|
US9487823B2
(en)
|
2002-12-20 |
2016-11-08 |
Qiagen Gmbh |
Nucleic acid amplification
|
EP1597395A2
(de)
|
2003-02-21 |
2005-11-23 |
Nuevolution A/S |
Methode zur herstellung einer bibliothek der zweiten generation
|
US8043834B2
(en)
|
2003-03-31 |
2011-10-25 |
Qiagen Gmbh |
Universal reagents for rolling circle amplification and methods of use
|
WO2004092375A2
(en)
*
|
2003-04-15 |
2004-10-28 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. |
Ligation-based synthesis of oligonucleotides with block structure
|
WO2005017153A2
(en)
*
|
2003-08-04 |
2005-02-24 |
Blue Heron Biotechnology, Inc. |
Methods for synthesis of defined polynucleotides
|
DK1670939T3
(da)
|
2003-09-18 |
2010-03-01 |
Nuevolution As |
Fremgangsmåde til opnåelse af strukturel information om et kodet molekyle og fremgangsmåde til udvælgelse af forbindelser
|
JP2007508825A
(ja)
*
|
2003-10-15 |
2007-04-12 |
ブルー ヘロン バイオテクノロジー インコーポレイテッド |
ポリヌクレオチド生成のための固相方法
|
WO2005078122A2
(en)
*
|
2004-02-17 |
2005-08-25 |
Nuevolution A/S |
Method for enrichment involving elimination by mismatch hybridisation
|
CA2584984A1
(en)
*
|
2004-10-18 |
2006-04-27 |
Codon Devices, Inc. |
Methods for assembly of high fidelity synthetic polynucleotides
|
US20070122817A1
(en)
*
|
2005-02-28 |
2007-05-31 |
George Church |
Methods for assembly of high fidelity synthetic polynucleotides
|
WO2006065598A2
(en)
*
|
2004-12-13 |
2006-06-22 |
Geneohm Sciences, Inc. |
Fluidic cartridges for electrochemical detection of dna
|
WO2007040592A1
(en)
*
|
2005-03-10 |
2007-04-12 |
Gao, Xiaolian |
Making nucleic acid sequences in parallel and use
|
US8309303B2
(en)
|
2005-04-01 |
2012-11-13 |
Qiagen Gmbh |
Reverse transcription and amplification of RNA with simultaneous degradation of DNA
|
US20060292585A1
(en)
*
|
2005-06-24 |
2006-12-28 |
Affymetrix, Inc. |
Analysis of methylation using nucleic acid arrays
|
DE102005029810B4
(de)
*
|
2005-06-27 |
2008-11-13 |
Siemens Ag |
Verfahren zum Nachweis von Nukleotidsequenzen, Verwendung des Verfahrens und Testbesteck
|
EP1762627A1
(de)
|
2005-09-09 |
2007-03-14 |
Qiagen GmbH |
Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
|
DK2336315T3
(da)
|
2005-12-01 |
2017-11-06 |
Nuevolution As |
Fremgangsmåde til enzymatisk kodning ved effektiv syntese af store biblioteker
|
US8551697B1
(en)
*
|
2005-12-09 |
2013-10-08 |
Applied Biosystems, Llc |
Electrochemical polynucleotide detection comprising ligation
|
US7901882B2
(en)
|
2006-03-31 |
2011-03-08 |
Affymetrix, Inc. |
Analysis of methylation using nucleic acid arrays
|
JP2007275006A
(ja)
*
|
2006-04-10 |
2007-10-25 |
Hitachi High-Technologies Corp |
核酸検出用プローブ作製法
|
WO2007136834A2
(en)
*
|
2006-05-19 |
2007-11-29 |
Codon Devices, Inc. |
Combined extension and ligation for nucleic acid assembly
|
WO2008027558A2
(en)
|
2006-08-31 |
2008-03-06 |
Codon Devices, Inc. |
Iterative nucleic acid assembly using activation of vector-encoded traits
|
AU2008343589A1
(en)
|
2007-12-19 |
2009-07-09 |
Centocor Ortho Biotech Inc. |
Design and generation of human de novo pIX phage display libraries via fusion to pIX or pVII, vectors, antibodies and methods
|
WO2009138954A2
(en)
|
2008-05-14 |
2009-11-19 |
British Columbia Cancer Agency Branch |
Gene synthesis by convergent assembly of oligonucleotide subsets
|
KR20100089688A
(ko)
*
|
2009-02-04 |
2010-08-12 |
삼성전자주식회사 |
표적핵산의 서열을 분석하는 방법
|
DK3211126T3
(da)
|
2009-02-13 |
2020-12-21 |
X Chem Inc |
Fremgangsmåder til dannelse og screening af dna-kodede biblioteker
|
WO2011056872A2
(en)
|
2009-11-03 |
2011-05-12 |
Gen9, Inc. |
Methods and microfluidic devices for the manipulation of droplets in high fidelity polynucleotide assembly
|
WO2011066185A1
(en)
|
2009-11-25 |
2011-06-03 |
Gen9, Inc. |
Microfluidic devices and methods for gene synthesis
|
WO2011085075A2
(en)
|
2010-01-07 |
2011-07-14 |
Gen9, Inc. |
Assembly of high fidelity polynucleotides
|
EP3540059A1
(de)
|
2010-04-16 |
2019-09-18 |
Nuevolution A/S |
Bifunktionelle komplexe und verfahren zur herstellung sowie verwendung derartiger komplexe
|
US9187777B2
(en)
|
2010-05-28 |
2015-11-17 |
Gen9, Inc. |
Methods and devices for in situ nucleic acid synthesis
|
CN103502448B
(zh)
|
2010-11-12 |
2017-03-29 |
Gen9股份有限公司 |
核酸合成的方法和设备
|
WO2012064975A1
(en)
|
2010-11-12 |
2012-05-18 |
Gen9, Inc. |
Protein arrays and methods of using and making the same
|
WO2013032850A2
(en)
|
2011-08-26 |
2013-03-07 |
Gen9, Inc. |
Compositions and methods for high fidelity assembly of nucleic acids
|
EP2748357B1
(de)
|
2011-09-07 |
2018-04-04 |
X-Chem, Inc. |
Verfahren zur markierung dna-kodierter bibliotheken
|
JP5920763B2
(ja)
*
|
2011-10-05 |
2016-05-18 |
国立大学法人名古屋大学 |
蛍光標識オリゴヌクレオチド誘導体及びその利用
|
US9150853B2
(en)
|
2012-03-21 |
2015-10-06 |
Gen9, Inc. |
Methods for screening proteins using DNA encoded chemical libraries as templates for enzyme catalysis
|
EP4001427A1
(de)
|
2012-04-24 |
2022-05-25 |
Gen9, Inc. |
Verfahren zum sortieren von nukleinsäuren und zur multiplexierten, vorbereitenden in-vitro-klonung
|
CN113512577A
(zh)
|
2012-06-25 |
2021-10-19 |
Gen9股份有限公司 |
用于核酸组装和高通量测序的方法
|
KR102146721B1
(ko)
|
2012-07-13 |
2020-08-21 |
엑스-켐, 인크. |
폴리머라제에 의해 판독가능하지 않은 코딩 올리고뉴클레오티드 연결을 갖는 dna-코딩된 라이브러리
|
BR112015003354A8
(pt)
|
2012-08-14 |
2018-01-16 |
10X Genomics Inc |
métodos e composições de microcápsula
|
US10323279B2
(en)
|
2012-08-14 |
2019-06-18 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US10273541B2
(en)
|
2012-08-14 |
2019-04-30 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US9951386B2
(en)
|
2014-06-26 |
2018-04-24 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US9701998B2
(en)
|
2012-12-14 |
2017-07-11 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US10400280B2
(en)
|
2012-08-14 |
2019-09-03 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US11591637B2
(en)
|
2012-08-14 |
2023-02-28 |
10X Genomics, Inc. |
Compositions and methods for sample processing
|
US10221442B2
(en)
|
2012-08-14 |
2019-03-05 |
10X Genomics, Inc. |
Compositions and methods for sample processing
|
US10752949B2
(en)
|
2012-08-14 |
2020-08-25 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US10533221B2
(en)
|
2012-12-14 |
2020-01-14 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
CA2894694C
(en)
|
2012-12-14 |
2023-04-25 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
WO2014124336A2
(en)
|
2013-02-08 |
2014-08-14 |
10X Technologies, Inc. |
Partitioning and processing of analytes and other species
|
CN108467863B
(zh)
|
2013-03-15 |
2022-01-25 |
Gen9股份有限公司 |
多重核酸合成的组合物和方法
|
EP3074554B1
(de)
|
2013-11-27 |
2021-05-19 |
Gen9, Inc. |
Nukleinsäurebibliotheken und verfahren zur herstellung davon
|
CA2945628A1
(en)
*
|
2013-12-09 |
2015-06-18 |
Integrated Dna Technologies, Inc. |
Long nuceic acid sequences containing variable regions
|
EP2883963A1
(de)
*
|
2013-12-16 |
2015-06-17 |
Alacris Theranostics GmbH |
Verfahren zur Erzeugung von Oligonukleotid-Arrays mit In-situ-Blocksyntheseansatz
|
US9824068B2
(en)
|
2013-12-16 |
2017-11-21 |
10X Genomics, Inc. |
Methods and apparatus for sorting data
|
CN110548550B
(zh)
|
2014-04-10 |
2022-03-08 |
10X基因组学有限公司 |
用于封装和分割试剂的流体装置、系统和方法及其应用
|
CA2953374A1
(en)
|
2014-06-26 |
2015-12-30 |
10X Genomics, Inc. |
Methods of analyzing nucleic acids from individual cells or cell populations
|
US9975122B2
(en)
|
2014-11-05 |
2018-05-22 |
10X Genomics, Inc. |
Instrument systems for integrated sample processing
|
MX367432B
(es)
|
2015-01-12 |
2019-08-08 |
10X Genomics Inc |
Procesos y sistemas para la preparación de bibliotecas de secuenciación de ácido nucleico y bibliotecas preparadas con estos.
|
EP4286516A3
(de)
|
2015-02-24 |
2024-03-06 |
10X Genomics, Inc. |
Partitionsverarbeitungsverfahren und -systeme
|
WO2017015348A1
(en)
*
|
2015-07-20 |
2017-01-26 |
The Regents Of The University Of California |
Sequence-independent nucleic acid assembly
|
WO2017027779A1
(en)
*
|
2015-08-13 |
2017-02-16 |
Centrillion Technology Holdings Corporation |
Library construction using y-adapters and vanishing restriction sites
|
US11371094B2
(en)
|
2015-11-19 |
2022-06-28 |
10X Genomics, Inc. |
Systems and methods for nucleic acid processing using degenerate nucleotides
|
SG11201804086VA
(en)
|
2015-12-04 |
2018-06-28 |
10X Genomics Inc |
Methods and compositions for nucleic acid analysis
|
CN108779491B
(zh)
|
2016-02-11 |
2021-03-09 |
10X基因组学有限公司 |
用于全基因组序列数据的从头组装的系统、方法和介质
|
US10907195B1
(en)
*
|
2016-02-16 |
2021-02-02 |
Pharmaseq, Inc. |
Devices and methods for assembling extremely long DNA molecules
|
CN109715824A
(zh)
|
2016-05-09 |
2019-05-03 |
哈佛学院董事及会员团体 |
酶促核酸合成
|
WO2017197338A1
(en)
|
2016-05-13 |
2017-11-16 |
10X Genomics, Inc. |
Microfluidic systems and methods of use
|
WO2018005720A1
(en)
*
|
2016-06-30 |
2018-01-04 |
President And Fellows Of Harvard College |
Method of determining the molecular binding between libraries of molecules
|
US10550429B2
(en)
|
2016-12-22 |
2020-02-04 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US10815525B2
(en)
|
2016-12-22 |
2020-10-27 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
EP4310183A3
(de)
|
2017-01-30 |
2024-02-21 |
10X Genomics, Inc. |
Verfahren und systeme zur tröpfchenbasierten einzelzellenbarcodierung
|
US10995333B2
(en)
|
2017-02-06 |
2021-05-04 |
10X Genomics, Inc. |
Systems and methods for nucleic acid preparation
|
US20180340169A1
(en)
|
2017-05-26 |
2018-11-29 |
10X Genomics, Inc. |
Single cell analysis of transposase accessible chromatin
|
EP4230746A3
(de)
|
2017-05-26 |
2023-11-01 |
10X Genomics, Inc. |
Einzelzellanalyse von transposase-zugänglichem chromatin
|
US10837047B2
(en)
|
2017-10-04 |
2020-11-17 |
10X Genomics, Inc. |
Compositions, methods, and systems for bead formation using improved polymers
|
WO2019084043A1
(en)
|
2017-10-26 |
2019-05-02 |
10X Genomics, Inc. |
METHODS AND SYSTEMS FOR NUCLEIC ACID PREPARATION AND CHROMATIN ANALYSIS
|
CN111479631B
(zh)
|
2017-10-27 |
2022-02-22 |
10X基因组学有限公司 |
用于样品制备和分析的方法和系统
|
EP3625361A1
(de)
|
2017-11-15 |
2020-03-25 |
10X Genomics, Inc. |
Funktionalisierte gelperlen
|
US10829815B2
(en)
|
2017-11-17 |
2020-11-10 |
10X Genomics, Inc. |
Methods and systems for associating physical and genetic properties of biological particles
|
WO2019108851A1
(en)
|
2017-11-30 |
2019-06-06 |
10X Genomics, Inc. |
Systems and methods for nucleic acid preparation and analysis
|
WO2019140353A1
(en)
*
|
2018-01-12 |
2019-07-18 |
Camena Bioscience Limited |
Compositions and methods for template-free geometric enzymatic nucleic acid synthesis
|
EP3752832A1
(de)
|
2018-02-12 |
2020-12-23 |
10X Genomics, Inc. |
Verfahren zur charakterisierung mehrerer analyten aus einzelnen zellen oder zellpopulationen
|
US11639928B2
(en)
|
2018-02-22 |
2023-05-02 |
10X Genomics, Inc. |
Methods and systems for characterizing analytes from individual cells or cell populations
|
WO2019195166A1
(en)
|
2018-04-06 |
2019-10-10 |
10X Genomics, Inc. |
Systems and methods for quality control in single cell processing
|
US11932899B2
(en)
|
2018-06-07 |
2024-03-19 |
10X Genomics, Inc. |
Methods and systems for characterizing nucleic acid molecules
|
US11703427B2
(en)
|
2018-06-25 |
2023-07-18 |
10X Genomics, Inc. |
Methods and systems for cell and bead processing
|
US20200032335A1
(en)
|
2018-07-27 |
2020-01-30 |
10X Genomics, Inc. |
Systems and methods for metabolome analysis
|
WO2020041360A1
(en)
|
2018-08-21 |
2020-02-27 |
Quidel Corporation |
Dbpa antibodies and uses thereof
|
US11459607B1
(en)
|
2018-12-10 |
2022-10-04 |
10X Genomics, Inc. |
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|
US11845983B1
(en)
|
2019-01-09 |
2023-12-19 |
10X Genomics, Inc. |
Methods and systems for multiplexing of droplet based assays
|
US11467153B2
(en)
|
2019-02-12 |
2022-10-11 |
10X Genomics, Inc. |
Methods for processing nucleic acid molecules
|
US11851683B1
(en)
|
2019-02-12 |
2023-12-26 |
10X Genomics, Inc. |
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|
WO2020168013A1
(en)
|
2019-02-12 |
2020-08-20 |
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|
US11655499B1
(en)
|
2019-02-25 |
2023-05-23 |
10X Genomics, Inc. |
Detection of sequence elements in nucleic acid molecules
|
US11920183B2
(en)
|
2019-03-11 |
2024-03-05 |
10X Genomics, Inc. |
Systems and methods for processing optically tagged beads
|
AU2020408213A1
(en)
|
2019-12-19 |
2022-06-23 |
Quidel Corporation |
Monoclonal antibody fusions
|
US11851700B1
(en)
|
2020-05-13 |
2023-12-26 |
10X Genomics, Inc. |
Methods, kits, and compositions for processing extracellular molecules
|
AU2022227563A1
(en)
|
2021-02-23 |
2023-08-24 |
10X Genomics, Inc. |
Probe-based analysis of nucleic acids and proteins
|