ATE257824T1 - Verfahren zur herstellung von (9alpha, 13alpha, - Google Patents

Verfahren zur herstellung von (9alpha, 13alpha,

Info

Publication number
ATE257824T1
ATE257824T1 AT97116753T AT97116753T ATE257824T1 AT E257824 T1 ATE257824 T1 AT E257824T1 AT 97116753 T AT97116753 T AT 97116753T AT 97116753 T AT97116753 T AT 97116753T AT E257824 T1 ATE257824 T1 AT E257824T1
Authority
AT
Austria
Prior art keywords
alpha
formula
alkylsulfonic acid
dextromethorphan
13alpha
Prior art date
Application number
AT97116753T
Other languages
English (en)
Inventor
Christof Wehrli
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE257824T1 publication Critical patent/ATE257824T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT97116753T 1996-10-02 1997-09-26 Verfahren zur herstellung von (9alpha, 13alpha, ATE257824T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96115783 1996-10-02

Publications (1)

Publication Number Publication Date
ATE257824T1 true ATE257824T1 (de) 2004-01-15

Family

ID=8223254

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97116753T ATE257824T1 (de) 1996-10-02 1997-09-26 Verfahren zur herstellung von (9alpha, 13alpha,

Country Status (7)

Country Link
US (1) US5905153A (de)
JP (1) JPH10114749A (de)
CN (1) CN1102143C (de)
AT (1) ATE257824T1 (de)
BR (1) BR9704957A (de)
DE (1) DE59711203D1 (de)
ID (1) ID19595A (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040204862A1 (en) * 2003-04-11 2004-10-14 Wainer Irving W. Computer-based model for identification and characterization for non-competitive inhibitors of nicotinic acetylcholine receptors and related ligand-gated ion channel receptors
CN103044327B (zh) * 2013-01-07 2014-12-17 苏州立新制药有限公司 一种右美沙芬的制备方法
CN103265489B (zh) * 2013-06-17 2015-03-25 苏州立新制药有限公司 ent-(14S)-3-甲氧基-17-甲基吗喃的制备方法
CN104761496B (zh) * 2015-04-02 2017-05-24 华东理工大学 一种右美沙芬中间体的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH560194A5 (de) * 1967-08-25 1975-03-27 Hoffmann La Roche
US3634429A (en) * 1969-09-30 1972-01-11 Hoffmann La Roche Morphinan derivatives and preparation thereof
US3810899A (en) * 1972-03-10 1974-05-14 Hoffmann La Roche 2-hydroxy-n-substituted-morphinan derivatives
US3914234A (en) * 1972-03-10 1975-10-21 Hoffmann La Roche 2-Lower alkoxy-N-substituted-morphinan derivatives
ZA73988B (en) * 1972-03-10 1973-10-31 Hoffmann La Roche Morphinan derivatives
US3914233A (en) * 1972-10-20 1975-10-21 Hoffmann La Roche 4-Hydroxy-N-substituted morphinan derivatives
US3914232A (en) * 1972-10-20 1975-10-21 Hoffmann La Roche 2-And 4-acryloxy-N-substituted-morphinan derivatives
DK168069B1 (da) * 1987-11-11 1994-01-31 Hoffmann La Roche Isoquinolinderivater og en fremgangsmaade til fremstilling af octahydroisoquinoliner ud fra derivaterne

Also Published As

Publication number Publication date
JPH10114749A (ja) 1998-05-06
ID19595A (id) 1998-07-23
US5905153A (en) 1999-05-18
DE59711203D1 (de) 2004-02-19
CN1178790A (zh) 1998-04-15
CN1102143C (zh) 2003-02-26
BR9704957A (pt) 1998-10-27

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