ATE257469T1 - Verfahren zur herstellung von (z)-1-(1-(4- methoxybenzyliden)-1,2,3,4,5,6,7,8-octahydro- isochinolin-2-yl)alkanonen - Google Patents

Verfahren zur herstellung von (z)-1-(1-(4- methoxybenzyliden)-1,2,3,4,5,6,7,8-octahydro- isochinolin-2-yl)alkanonen

Info

Publication number
ATE257469T1
ATE257469T1 AT97116763T AT97116763T ATE257469T1 AT E257469 T1 ATE257469 T1 AT E257469T1 AT 97116763 T AT97116763 T AT 97116763T AT 97116763 T AT97116763 T AT 97116763T AT E257469 T1 ATE257469 T1 AT E257469T1
Authority
AT
Austria
Prior art keywords
alkanones
isoquinolin
octahydro
methoxybenzyliden
producing
Prior art date
Application number
AT97116763T
Other languages
English (en)
Inventor
Christof Wehrli
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE257469T1 publication Critical patent/ATE257469T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT97116763T 1996-10-02 1997-09-26 Verfahren zur herstellung von (z)-1-(1-(4- methoxybenzyliden)-1,2,3,4,5,6,7,8-octahydro- isochinolin-2-yl)alkanonen ATE257469T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96115782 1996-10-02

Publications (1)

Publication Number Publication Date
ATE257469T1 true ATE257469T1 (de) 2004-01-15

Family

ID=8223253

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97116763T ATE257469T1 (de) 1996-10-02 1997-09-26 Verfahren zur herstellung von (z)-1-(1-(4- methoxybenzyliden)-1,2,3,4,5,6,7,8-octahydro- isochinolin-2-yl)alkanonen

Country Status (7)

Country Link
US (1) US5849917A (de)
JP (1) JPH10114775A (de)
CN (1) CN1109672C (de)
AT (1) ATE257469T1 (de)
BR (1) BR9704946A (de)
DE (1) DE59711177D1 (de)
ID (1) ID19563A (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103044327B (zh) * 2013-01-07 2014-12-17 苏州立新制药有限公司 一种右美沙芬的制备方法
CN103073495B (zh) * 2013-02-06 2015-08-05 苏州立新制药有限公司 一种ent-3-甲氧基吗喃的制备方法
CN110172076B (zh) * 2019-06-14 2021-08-27 安徽师范大学 一种含环外双键喹啉衍生物及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3810899A (en) * 1972-03-10 1974-05-14 Hoffmann La Roche 2-hydroxy-n-substituted-morphinan derivatives
US3914234A (en) * 1972-03-10 1975-10-21 Hoffmann La Roche 2-Lower alkoxy-N-substituted-morphinan derivatives
ZA73988B (en) * 1972-03-10 1973-10-31 Hoffmann La Roche Morphinan derivatives
US3914233A (en) * 1972-10-20 1975-10-21 Hoffmann La Roche 4-Hydroxy-N-substituted morphinan derivatives
US3914232A (en) * 1972-10-20 1975-10-21 Hoffmann La Roche 2-And 4-acryloxy-N-substituted-morphinan derivatives
DK168069B1 (da) * 1987-11-11 1994-01-31 Hoffmann La Roche Isoquinolinderivater og en fremgangsmaade til fremstilling af octahydroisoquinoliner ud fra derivaterne
DK0397042T3 (da) * 1989-05-10 1995-10-02 Hoffmann La Roche Fremstilling af isoquinolinderivater

Also Published As

Publication number Publication date
CN1178218A (zh) 1998-04-08
DE59711177D1 (de) 2004-02-12
CN1109672C (zh) 2003-05-28
US5849917A (en) 1998-12-15
JPH10114775A (ja) 1998-05-06
ID19563A (id) 1998-07-23
BR9704946A (pt) 1999-06-01

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