ATE256101T1 - Gelbe polymorphe form von 5-amino-2,4,6-triiodo-n,n'-bis(2,3-dihydroxypro yl)-isophthalamid - Google Patents
Gelbe polymorphe form von 5-amino-2,4,6-triiodo-n,n'-bis(2,3-dihydroxypro yl)-isophthalamidInfo
- Publication number
- ATE256101T1 ATE256101T1 AT98922947T AT98922947T ATE256101T1 AT E256101 T1 ATE256101 T1 AT E256101T1 AT 98922947 T AT98922947 T AT 98922947T AT 98922947 T AT98922947 T AT 98922947T AT E256101 T1 ATE256101 T1 AT E256101T1
- Authority
- AT
- Austria
- Prior art keywords
- triiodo
- isophthalamide
- bis
- amino
- yellow
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0438—Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Steroid Compounds (AREA)
- Polyamides (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9710726.2A GB9710726D0 (en) | 1997-05-23 | 1997-05-23 | Compound |
PCT/GB1998/001492 WO1998052911A1 (en) | 1997-05-23 | 1998-05-22 | Yellow polymorph of 5-amino-2,4,6-triiodo-n,n'-bis(2,3-dihydroxypropyl)-isophthalamide |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE256101T1 true ATE256101T1 (de) | 2003-12-15 |
Family
ID=10812988
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98922947T ATE256101T1 (de) | 1997-05-23 | 1998-05-22 | Gelbe polymorphe form von 5-amino-2,4,6-triiodo-n,n'-bis(2,3-dihydroxypro yl)-isophthalamid |
Country Status (18)
Country | Link |
---|---|
US (1) | US6337422B1 (de) |
EP (1) | EP0983230B1 (de) |
JP (1) | JP4476366B2 (de) |
KR (1) | KR100543856B1 (de) |
CN (1) | CN1161324C (de) |
AT (1) | ATE256101T1 (de) |
AU (1) | AU725565B2 (de) |
BR (1) | BRPI9809153B8 (de) |
CA (1) | CA2290544A1 (de) |
CZ (1) | CZ297243B6 (de) |
DE (1) | DE69820435T2 (de) |
GB (1) | GB9710726D0 (de) |
HU (1) | HU224128B1 (de) |
IL (1) | IL133100A (de) |
NO (1) | NO327490B1 (de) |
PL (1) | PL190905B1 (de) |
PT (1) | PT983230E (de) |
WO (1) | WO1998052911A1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7524515B2 (en) * | 2003-01-10 | 2009-04-28 | Mutual Pharmaceuticals, Inc. | Pharmaceutical safety dosage forms |
DE602007012208D1 (de) | 2006-02-15 | 2011-03-10 | Ge Healthcare As | Kontrastmittel |
US7662859B2 (en) | 2007-02-16 | 2010-02-16 | Ge Healthcare As | Contrast agents |
US20110256068A1 (en) | 2009-01-09 | 2011-10-20 | Wistand Lars-Goeran | Contrast media compositions |
US20110021833A1 (en) * | 2009-07-21 | 2011-01-27 | Ge Healthcare As | Crystallization of an intermediate for synthesizing non-ionic x-ray contrast agents |
EP2281807A1 (de) * | 2009-07-21 | 2011-02-09 | GE Healthcare AS | Entfärben von 5-amino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamid, ein Kontrastmittelzwischenprodukt |
US20110021834A1 (en) * | 2009-07-21 | 2011-01-27 | Ge Healthcare As | Continuous process of preparing intermediate for non-ionic x-ray contrast agents |
HUE056309T2 (hu) | 2011-09-19 | 2022-02-28 | Orexo Ab | Buprenorfint és naloxont tartalmazó szublingvális, abúzus-rezisztens tabletták |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1548594A (en) * | 1976-06-11 | 1979-07-18 | Nyegaard & Co As | Triiodoisophthalic acid amides |
US4256729A (en) * | 1979-03-23 | 1981-03-17 | Mallinckrodt, Inc. | N,N'-Bis-(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-keto-L-gulonamido)isophthalamide and radiological compositions containing same |
US4396598A (en) * | 1982-01-11 | 1983-08-02 | Mallinckrodt, Inc. | Triiodoisophthalamide X-ray contrast agent |
WO1989008101A1 (en) * | 1988-03-01 | 1989-09-08 | Mallinckrodt, Inc. | Nonionic x-ray contrast agents, compositions and methods |
US5013865A (en) * | 1988-04-06 | 1991-05-07 | Mallinckrodt, Inc. | Process for the preparation of 2,4,6-triiodo-5-amino-N-alkylisophthalamic acid and 2,4,6-triiodo-5-amino-isophthalamide compounds |
US5256393A (en) * | 1991-04-16 | 1993-10-26 | Mallinckrodt Medical, Inc. | Use of azeotropic distillation in process to dry 5-amino-N,N'bis (2,3-dihydroxypropyl)-2,4,6-triiodoisphthalamide |
EP0762900B1 (de) * | 1994-06-21 | 2001-11-21 | Mallinckrodt Inc. | Verbesserte synthese von ioversol unter verwendung einer mit phosphorsäure modifizierten koaddition |
GB9419206D0 (en) * | 1994-09-23 | 1994-11-09 | Nycomed Innovation Ab | Contrast media |
EP0828705B1 (de) * | 1995-05-24 | 2000-08-23 | Nycomed Imaging As | Verfahren zur iodierung |
-
1997
- 1997-05-23 GB GBGB9710726.2A patent/GB9710726D0/en active Pending
-
1998
- 1998-05-22 IL IL13310098A patent/IL133100A/en not_active IP Right Cessation
- 1998-05-22 KR KR1019997010757A patent/KR100543856B1/ko not_active IP Right Cessation
- 1998-05-22 HU HU0003637A patent/HU224128B1/hu active IP Right Grant
- 1998-05-22 CN CNB988053217A patent/CN1161324C/zh not_active Expired - Lifetime
- 1998-05-22 AU AU75407/98A patent/AU725565B2/en not_active Ceased
- 1998-05-22 WO PCT/GB1998/001492 patent/WO1998052911A1/en active IP Right Grant
- 1998-05-22 JP JP55014098A patent/JP4476366B2/ja not_active Expired - Lifetime
- 1998-05-22 PL PL336848A patent/PL190905B1/pl unknown
- 1998-05-22 DE DE69820435T patent/DE69820435T2/de not_active Expired - Lifetime
- 1998-05-22 CZ CZ0417199A patent/CZ297243B6/cs not_active IP Right Cessation
- 1998-05-22 CA CA002290544A patent/CA2290544A1/en not_active Abandoned
- 1998-05-22 EP EP98922947A patent/EP0983230B1/de not_active Expired - Lifetime
- 1998-05-22 BR BRPI9809153 patent/BRPI9809153B8/pt not_active IP Right Cessation
- 1998-05-22 PT PT98922947T patent/PT983230E/pt unknown
- 1998-05-22 AT AT98922947T patent/ATE256101T1/de active
-
1999
- 1999-11-12 US US09/438,385 patent/US6337422B1/en not_active Expired - Lifetime
- 1999-11-19 NO NO19995676A patent/NO327490B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CZ297243B6 (cs) | 2006-10-11 |
BRPI9809153B8 (pt) | 2021-07-06 |
AU7540798A (en) | 1998-12-11 |
NO995676L (no) | 1999-11-19 |
NO995676D0 (no) | 1999-11-19 |
WO1998052911A1 (en) | 1998-11-26 |
PL336848A1 (en) | 2000-07-17 |
PT983230E (pt) | 2004-04-30 |
HUP0003637A3 (en) | 2001-06-28 |
KR20010012794A (ko) | 2001-02-26 |
US6337422B1 (en) | 2002-01-08 |
BRPI9809153B1 (pt) | 2017-11-14 |
DE69820435T2 (de) | 2004-10-07 |
HUP0003637A1 (hu) | 2001-02-28 |
HU224128B1 (hu) | 2005-05-30 |
CZ417199A3 (cs) | 2000-05-17 |
BRPI9809153A (pt) | 2000-08-01 |
CN1161324C (zh) | 2004-08-11 |
EP0983230B1 (de) | 2003-12-10 |
KR100543856B1 (ko) | 2006-01-23 |
AU725565B2 (en) | 2000-10-12 |
CA2290544A1 (en) | 1998-11-26 |
JP4476366B2 (ja) | 2010-06-09 |
IL133100A (en) | 2004-07-25 |
PL190905B1 (pl) | 2006-02-28 |
NO327490B1 (no) | 2009-07-13 |
IL133100A0 (en) | 2001-03-19 |
CN1257479A (zh) | 2000-06-21 |
EP0983230A1 (de) | 2000-03-08 |
JP2001526678A (ja) | 2001-12-18 |
DE69820435D1 (en) | 2004-01-22 |
GB9710726D0 (en) | 1997-07-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0804421T3 (da) | 2-((Dihydro)pyrazolyl-3'-oxymethylen)-anilider som skadedyrsbekæmpelsesmidler og fungicider | |
ATE206409T1 (de) | N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1-h- benzo(b)(1,5)-diazepin-3-yl)-acetamide | |
IT1266943B1 (it) | Procedimento di sintesi vocale mediante concatenazione e parziale sovrapposizione di forme d'onda. | |
DE69501534D1 (de) | Synthese von 1,1,1,3,3-Pentafluorpropan | |
DK1100789T3 (da) | Substituerede benzoylcyclohexandioner | |
ATE256101T1 (de) | Gelbe polymorphe form von 5-amino-2,4,6-triiodo-n,n'-bis(2,3-dihydroxypro yl)-isophthalamid | |
DE69915591D1 (de) | Zusammensetzungen von 1,1,1,3,3-pentafluorpropan und trans-1,2-dichlorethylen | |
DE69434084D1 (de) | Diagnostische anwendungen von hydrazinoadenosine | |
ES2194102T3 (es) | Nuevas n-(2,4-dioxo-2,3,4,5-tetrahidro-1h-1,5-benzodiazepin-3-il)-3-amidas. | |
ATE103594T1 (de) | Fucosidase-inhibitoren. | |
DE59602691D1 (de) | Herstellung von primären Guerbetaminen | |
DK0696278T3 (da) | Herbicidtvirkende substituerede 1-phenyl- eller 1-pyridinylbenzotriazoler | |
LV11463A (lv) | Aizvietotu 4,6-diamino-5-cianpirimidinu iegusanas panemiens | |
DE69715196D1 (de) | Modifizierte form des hydrochlorids der r(-)-n-(4,4-di(-3-methylthien-2-yl)but-3-enyl)-nipecotinsäure | |
ITMI942671A0 (it) | Catalizzatori per la (co) polinerizzazione dell'etilene | |
DE69517535D1 (de) | Synthese von bis(2,2-dinitropropyl)formal (bdnpf) | |
DE69126612T2 (de) | Carbamate des indan-pyrrolidins | |
BR9809439A (pt) | Processos para preparação de benzotiofenos | |
FR2766819B1 (fr) | Nouvelles sulfonamides derivees d'anilines substituees utiles comme medicaments | |
DE69613921T2 (de) | Herstellung von Methylaminen | |
KR970702873A (ko) | 17β-시아노-3-에톡시-17α-하이드록시-6-메틸안드로스타-3,5,9-트리엔의 합성 방법(SYNTHESIS OF 17β-CYANO-3-ETHOXY-17α-HYDROXY-6-METHYLANDROSTA-3,5,9-TRIENE) | |
DE69800973D1 (de) | Bedienung von peripheriegeräten | |
ES2186164T3 (es) | Kodaistatinas a, b, c y d, un procedimiento para su produccion y su uso. | |
IT1271346B (it) | Precesso per la (co) polimerizzazione dell'etilene | |
NO972876D0 (no) | Disubstituerte p-fluorbenzolsulfonamider |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0983230 Country of ref document: EP |
|
EEFA | Change of the company name |