ATE251222T1 - Verfahren zur bestimung von ki-ras mutationen und dieses leistender testsatz - Google Patents

Verfahren zur bestimung von ki-ras mutationen und dieses leistender testsatz

Info

Publication number
ATE251222T1
ATE251222T1 AT96939373T AT96939373T ATE251222T1 AT E251222 T1 ATE251222 T1 AT E251222T1 AT 96939373 T AT96939373 T AT 96939373T AT 96939373 T AT96939373 T AT 96939373T AT E251222 T1 ATE251222 T1 AT E251222T1
Authority
AT
Austria
Prior art keywords
ras mutations
determining
test set
pcr
set performing
Prior art date
Application number
AT96939373T
Other languages
German (de)
English (en)
Inventor
Dagfinn Ogreid
Arve Ulvik
Jan Jacob Koornstra
Original Assignee
Nordiag As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordiag As filed Critical Nordiag As
Application granted granted Critical
Publication of ATE251222T1 publication Critical patent/ATE251222T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Holo Graphy (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electrically Operated Instructional Devices (AREA)
AT96939373T 1995-11-17 1996-11-15 Verfahren zur bestimung von ki-ras mutationen und dieses leistender testsatz ATE251222T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO954667A NO954667D0 (no) 1995-11-17 1995-11-17 Fremgangsmåte til deteksjon av Ki-ras mutasjoner
PCT/NO1996/000271 WO1997019191A1 (en) 1995-11-17 1996-11-15 Method for detection of ki-ras mutations and kit to perform it

Publications (1)

Publication Number Publication Date
ATE251222T1 true ATE251222T1 (de) 2003-10-15

Family

ID=19898772

Family Applications (2)

Application Number Title Priority Date Filing Date
AT96939373T ATE251222T1 (de) 1995-11-17 1996-11-15 Verfahren zur bestimung von ki-ras mutationen und dieses leistender testsatz
AT03020560T ATE318934T1 (de) 1995-11-17 1996-11-15 Verfahren zum nachweis von ki-ras mutationen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT03020560T ATE318934T1 (de) 1995-11-17 1996-11-15 Verfahren zum nachweis von ki-ras mutationen

Country Status (12)

Country Link
US (1) US6440661B1 (show.php)
EP (2) EP1394272B1 (show.php)
JP (1) JP2000500346A (show.php)
AT (2) ATE251222T1 (show.php)
AU (1) AU723980C (show.php)
DE (2) DE69630234T2 (show.php)
DK (2) DK1394272T3 (show.php)
ES (2) ES2262930T3 (show.php)
NO (2) NO954667D0 (show.php)
NZ (1) NZ322619A (show.php)
PT (2) PT1394272E (show.php)
WO (1) WO1997019191A1 (show.php)

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GB9715034D0 (en) * 1997-07-18 1997-09-24 Zeneca Ltd Assay
JP4794052B2 (ja) * 1999-04-09 2011-10-12 ジェンザイム・コーポレーション 癌の指標である核酸を検出するための方法
US6531302B1 (en) * 1999-04-12 2003-03-11 Nanogen/Becton Dickinson Partnership Anchored strand displacement amplification on an electronically addressable microchip
US6586177B1 (en) 1999-09-08 2003-07-01 Exact Sciences Corporation Methods for disease detection
US6849403B1 (en) 1999-09-08 2005-02-01 Exact Sciences Corporation Apparatus and method for drug screening
WO2001042781A2 (en) 1999-12-07 2001-06-14 Exact Sciences Corporation Supracolonic aerodigestive neoplasm detection
US7087414B2 (en) 2000-06-06 2006-08-08 Applera Corporation Methods and devices for multiplexing amplification reactions
US6605451B1 (en) * 2000-06-06 2003-08-12 Xtrana, Inc. Methods and devices for multiplexing amplification reactions
EP2351853A1 (en) * 2000-06-06 2011-08-03 Life Technologies Corporation Method and devices for multiplexing amplification reactions
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
WO2004051218A2 (en) 2002-12-04 2004-06-17 Applera Corporation Multiplex amplification of polynucleotides
WO2005113769A1 (en) * 2004-05-14 2005-12-01 Exact Sciences Corporation Method for stabilizing biological samples for nucleic acid analysis
US20070134709A1 (en) * 2005-12-14 2007-06-14 Xiping Xu Usages of MTHFR gene polymorphisms in predicting homocysteine level, disease risk, and treatment effects and related methods and kit
GB2435512A (en) 2006-02-23 2007-08-29 Mologic Ltd A binding assay and assay device
US8768629B2 (en) 2009-02-11 2014-07-01 Caris Mpi, Inc. Molecular profiling of tumors
CA2651995C (en) 2006-05-18 2017-04-25 Molecular Profiling Institute, Inc. System and method for determining individualized medical intervention for a disease state
US8583380B2 (en) 2008-09-05 2013-11-12 Aueon, Inc. Methods for stratifying and annotating cancer drug treatment options
WO2011109440A1 (en) 2010-03-01 2011-09-09 Caris Life Sciences Luxembourg Holdings Biomarkers for theranostics
CN107254538A (zh) 2008-11-12 2017-10-17 卡里斯生命科学瑞士控股有限责任公司 使用外来体来确定表现型的方法和系统
US20130005598A1 (en) * 2009-12-31 2013-01-03 The Regents Of The University Of Michigan Methods for Diagnosing The Malignant Potential of Pancreatic Cystic Lesions
US9469876B2 (en) 2010-04-06 2016-10-18 Caris Life Sciences Switzerland Holdings Gmbh Circulating biomarkers for metastatic prostate cancer
US9309556B2 (en) 2010-09-24 2016-04-12 The Board Of Trustees Of The Leland Stanford Junior University Direct capture, amplification and sequencing of target DNA using immobilized primers
GB201107466D0 (en) 2011-05-05 2011-06-15 Loktionov Alexandre Device and method for non-invasive collection of colorectal mucocellular layer and disease detection
CN102796811B (zh) * 2011-05-26 2013-12-18 上海赛安生物医药科技有限公司 检测kras突变的试剂及方法
BR112013032629A2 (pt) 2011-06-19 2017-08-01 Abogen Inc dispositivos, soluções e métodos para coletamento de amostra
WO2013074438A1 (en) * 2011-11-17 2013-05-23 The Johns Hopkins University Differential identification of pancreatic cysts
EP2926138A4 (en) * 2012-11-30 2016-09-14 Applied Proteomics Inc METHOD FOR DETERMINING THE STATE OF ACTIVITY BZW. THE RISK OF COLONCARCINOMES
CN106255753B (zh) 2014-03-07 2020-11-06 Dna吉诺特克股份有限公司 稳定化生物学样本中的核酸的组合物和方法
US9689874B2 (en) 2015-04-10 2017-06-27 Applied Proteomics, Inc. Protein biomarker panels for detecting colorectal cancer and advanced adenoma
US10753936B2 (en) 2016-07-22 2020-08-25 Van Andel Research Institute Method of detecting the level of a glycan
BR112020025764A2 (pt) 2018-06-19 2021-05-11 Biontech Us Inc. neoantígenos e usos dos mesmos

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4871838A (en) * 1985-07-23 1989-10-03 The Board Of Rijks Universiteit Leiden Probes and methods for detecting activated ras oncogenes
US5137806A (en) * 1989-12-11 1992-08-11 Board Of Regents, The University Of Texas System Methods and compositions for the detection of sequences in selected DNA molecules
IL97222A (en) * 1990-02-16 1995-08-31 Orion Yhtymae Oy Method and reagent for determining specific nucleotide variations
CA2132874C (en) 1992-04-01 2003-08-19 Bert Vogelstein Methods of detecting mammalian nucleic acids isolated from stool specimen and reagents therefor
EP0655090B1 (en) * 1992-04-27 2000-12-27 The Trustees Of Dartmouth College Detection of gene sequences in biological fluids
JPH06167492A (ja) * 1992-11-30 1994-06-14 Otsuka Pharmaceut Co Ltd 変異癌遺伝子の検出測定方法
DE19512369A1 (de) * 1995-04-01 1996-10-02 Boehringer Mannheim Gmbh Vorrichtung zur Isolierung von Nukleinsäuren

Also Published As

Publication number Publication date
US6440661B1 (en) 2002-08-27
DE69630234D1 (de) 2003-11-06
EP1394272A1 (en) 2004-03-03
ES2262930T3 (es) 2006-12-01
DK1394272T3 (da) 2006-07-03
ES2208766T3 (es) 2004-06-16
NO982246L (no) 1998-07-07
NO982246D0 (no) 1998-05-15
DK0868529T3 (da) 2004-02-02
ATE318934T1 (de) 2006-03-15
EP1394272B1 (en) 2006-03-01
NZ322619A (en) 1999-04-29
PT868529E (pt) 2004-02-27
DE69635848T2 (de) 2006-11-30
AU723980B2 (en) 2000-09-07
DE69630234T2 (de) 2004-08-19
EP0868529B1 (en) 2003-10-01
JP2000500346A (ja) 2000-01-18
WO1997019191A1 (en) 1997-05-29
AU7656996A (en) 1997-06-11
DE69635848D1 (de) 2006-04-27
NO954667D0 (no) 1995-11-17
NO324963B1 (no) 2008-01-14
EP0868529A1 (en) 1998-10-07
AU723980C (en) 2002-10-24
PT1394272E (pt) 2006-07-31

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