ATE333517T1 - Verfahren und sondenset zur erkennung von krebs - Google Patents

Verfahren und sondenset zur erkennung von krebs

Info

Publication number
ATE333517T1
ATE333517T1 AT00301762T AT00301762T ATE333517T1 AT E333517 T1 ATE333517 T1 AT E333517T1 AT 00301762 T AT00301762 T AT 00301762T AT 00301762 T AT00301762 T AT 00301762T AT E333517 T1 ATE333517 T1 AT E333517T1
Authority
AT
Austria
Prior art keywords
detecting cancer
probe set
chromosomal probes
biological sample
cells
Prior art date
Application number
AT00301762T
Other languages
English (en)
Inventor
Kevin C Halling
Robert B Jenkins
Walter King
Irina A Sokolova
Steven A Seelig
Original Assignee
Vysis Inc
Mayo Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vysis Inc, Mayo Foundation filed Critical Vysis Inc
Application granted granted Critical
Publication of ATE333517T1 publication Critical patent/ATE333517T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6841In situ hybridisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2537/00Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2537/00Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/16Assays for determining copy number or wherein the copy number is of special importance
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
AT00301762T 1999-03-05 2000-03-03 Verfahren und sondenset zur erkennung von krebs ATE333517T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/264,149 US6174681B1 (en) 1999-03-05 1999-03-05 Method and probe set for detecting cancer

Publications (1)

Publication Number Publication Date
ATE333517T1 true ATE333517T1 (de) 2006-08-15

Family

ID=23004816

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00301762T ATE333517T1 (de) 1999-03-05 2000-03-03 Verfahren und sondenset zur erkennung von krebs

Country Status (7)

Country Link
US (9) US6174681B1 (de)
EP (2) EP1650313B1 (de)
JP (4) JP4986316B2 (de)
AT (1) ATE333517T1 (de)
DE (1) DE60029369T2 (de)
DK (1) DK1650313T3 (de)
ES (1) ES2528180T3 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0878552A1 (de) * 1997-05-13 1998-11-18 Erasmus Universiteit Rotterdam Molekularer Nachweis von chromosomalen Veränderungen
JP2002513587A (ja) * 1998-05-04 2002-05-14 ダコ エー エス 染色体異常を検出するための方法およびプローブ
US6174681B1 (en) 1999-03-05 2001-01-16 Mayo Foundation For Medical Education And Research Method and probe set for detecting cancer
AU2001281136A1 (en) * 2000-08-04 2002-02-18 Board Of Regents, The University Of Texas System Detection and diagnosis of smoking related cancers
CA2438267C (en) * 2001-02-20 2012-05-15 Larry E. Morrison Methods and probes for the detection of cancer
US6977162B2 (en) * 2002-03-01 2005-12-20 Ravgen, Inc. Rapid analysis of variations in a genome
NZ535045A (en) * 2002-03-01 2008-04-30 Ravgen Inc Rapid analysis of variations in a genome
US7727720B2 (en) * 2002-05-08 2010-06-01 Ravgen, Inc. Methods for detection of genetic disorders
US20070178478A1 (en) * 2002-05-08 2007-08-02 Dhallan Ravinder S Methods for detection of genetic disorders
US7442506B2 (en) * 2002-05-08 2008-10-28 Ravgen, Inc. Methods for detection of genetic disorders
US7217515B2 (en) * 2002-09-30 2007-05-15 Chi Mei Foundation Medical Center HURP gene as a molecular marker for bladder cancer
US7267648B2 (en) * 2003-03-31 2007-09-11 Olympus Corporation Magnifying image pickup unit for an endoscope, an endoscope for in vivo cellular observation that uses it, and endoscopic, in vivo cellular observation methods
US20040197839A1 (en) * 2003-04-04 2004-10-07 Bioview Ltd. Methods of detecting cancer cells in biological samples
WO2005001137A2 (en) 2003-06-09 2005-01-06 Vysis, Inc. Detection of high grade dysplasia in cervical cells
US20040248107A1 (en) * 2003-06-09 2004-12-09 Sokolova Irina A. Detection of high grade dysplasia in cervical cells
US7252946B2 (en) * 2004-01-27 2007-08-07 Zoragen, Inc. Nucleic acid detection
US20060047337A1 (en) 2004-08-27 2006-03-02 Brenneman Rodney A Device and method for establishing an artificial arterio-venous fistula
US9706997B2 (en) * 2004-08-27 2017-07-18 Rox Medical, Inc. Device and method for establishing an artificial arterio-venous fistula
US7828814B2 (en) * 2004-08-27 2010-11-09 Rox Medical, Inc. Device and method for establishing an artificial arterio-venous fistula
WO2006026714A2 (en) * 2004-08-31 2006-03-09 Board Of Regents, The University Of Texas System Diagnosis and prognosis of cancer based on telomere length as measured on cytological specimens
US8226592B2 (en) 2004-12-15 2012-07-24 Rox Medical, Inc. Method of treating COPD with artificial arterio-venous fistula and flow mediating systems
EP2540842B8 (de) 2005-02-18 2016-06-01 Abbott Molecular Inc. Verfahren und Sonden zur Erkennung von Speiseröhrenkrebs
US8105768B2 (en) 2005-03-09 2012-01-31 Abbott Laboratories Methods of identifying patients for treatment with HER-2/neu inhibitors based on detection of HER-2/neu and TOP2A gene copy number
CA2617501C (en) 2005-09-02 2019-12-24 The Regents Of The University Of California Methods and combinations of probes to chromosomal regions for detecting melanoma
WO2007087612A2 (en) * 2006-01-25 2007-08-02 Board Of Regents, The University Of Texas System Detection and diagnosis of smoking related cancers
US20080026366A1 (en) * 2006-06-07 2008-01-31 Newcomer Supply, Inc. Biological fixative and method of using the biological fixative
US7960110B2 (en) 2006-11-15 2011-06-14 The Regents Of The University Of California Detection of chromosomal region copy number changes to diagnose melanoma
WO2009015359A2 (en) * 2007-07-26 2009-01-29 Cellay, Llc Highly visible chromosome-specific probes and related methods
US20090258365A1 (en) * 2008-03-25 2009-10-15 Terstappen Leon W M M METHOD FOR DETECTING IGF1R/Chr 15 in CIRCULATING TUMOR CELLS USING FISH
US20090280491A1 (en) * 2008-03-27 2009-11-12 The Trustees Of Columbia University In The City Of New York Predicting cancer invasiveness
WO2010039862A1 (en) * 2008-09-30 2010-04-08 Rox Medical, Inc. Methods for screening and treating patients with compromised cardiopulmonary function
US8785131B2 (en) * 2008-11-11 2014-07-22 Abbott Laboratories Prognostic test for early stage non small cell lung cancer (NSCLC)
FR2938269B1 (fr) * 2008-11-13 2012-09-28 Array Genomics Procede de detection urinaire du cancer de la vessie
US20100129796A1 (en) * 2008-11-24 2010-05-27 Micah Halpern Dye probe fluorescence resonance energy transfer genotyping
WO2011056490A1 (en) 2009-10-26 2011-05-12 Abbott Laboratories Diagnostic methods for determining prognosis of non-small cell lung cancer
CN107090490A (zh) 2009-10-26 2017-08-25 雅培分子公司 用于测定非小细胞肺癌预后的诊断方法
DE102011100242A1 (de) 2011-05-02 2012-11-08 Zytovision Gmbh Verfahren zur Detektion von Chromosomenaberration
ES2601460T3 (es) * 2011-12-30 2017-02-15 Abbott Molecular Inc. Materiales y métodos para el diagnóstico del cáncer de vejiga y el control de la recurrencia del mismo
WO2014075083A1 (en) 2012-11-09 2014-05-15 The Regents Of The University Of California Methods for predicting age and identifying agents that induce or inhibit premature aging
US10370720B2 (en) 2014-02-12 2019-08-06 Leica Biosystems Newcastle Ltd. Kit and method for detecting bladder cancer
EP3109324B1 (de) 2015-06-23 2018-09-19 ZytoVision GmbH Verfahren zur detektion von chromosomenaberrationen
EP3130680A1 (de) 2015-08-11 2017-02-15 Universitat de Girona Verfahren zur detektion, nachverfolgung und/oder klassifikation von darmerkrankungen
WO2019152504A1 (en) 2018-01-30 2019-08-08 Board Of Regents, The University Of Texas System Multi-color fish test for bladder cancer detection

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5447841A (en) 1986-01-16 1995-09-05 The Regents Of The Univ. Of California Methods for chromosome-specific staining
US5756696A (en) * 1986-01-16 1998-05-26 Regents Of The University Of California Compositions for chromosome-specific staining
US5028525A (en) * 1986-11-24 1991-07-02 Regents Of The University Of California Method of preparing and applying single stranded DNA probes to double stranded target DNAs in situ
US5874234A (en) * 1990-08-01 1999-02-23 Johns Hopkins University Assay for a novel mammalian protein associated with uncontrolled cell division
US5491224A (en) 1990-09-20 1996-02-13 Bittner; Michael L. Direct label transaminated DNA probe compositions for chromosome identification and methods for their manufacture
WO1993018186A1 (en) * 1992-03-04 1993-09-16 The Regents Of The University Of California Comparative genomic hybridization (cgh)
AU5355594A (en) 1992-10-09 1994-05-09 Oncor, Inc. Methods for the detection of chromosome structural abnormalities by (in situ) hybridization to fixed tissue
WO1995013398A1 (en) 1993-11-12 1995-05-18 Oncor, Inc. Detection of bladder cancer
CN1128049A (zh) * 1994-03-18 1996-07-31 犹他大学研究基金会 多肿瘤抑制因子基因种系突变及检测该基因癌肿倾向性的方法
CA2241364A1 (en) * 1995-12-22 1997-07-03 Bio-Rad Laboratories, Inc. Method and apparatus for conducting multiparametric fluorescence in situ hybridization
US5759781A (en) * 1995-12-22 1998-06-02 Yale University Multiparametric fluorescence in situ hybridization
GB9704054D0 (en) * 1997-02-27 1997-04-16 Univ Cambridge Tech Assay
US6174681B1 (en) 1999-03-05 2001-01-16 Mayo Foundation For Medical Education And Research Method and probe set for detecting cancer

Also Published As

Publication number Publication date
DE60029369T2 (de) 2007-07-12
US20130316344A1 (en) 2013-11-28
DE60029369D1 (de) 2006-08-31
JP4986316B2 (ja) 2012-07-25
JP2017131248A (ja) 2017-08-03
EP1650313A1 (de) 2006-04-26
EP1035215B1 (de) 2006-07-19
US7998670B2 (en) 2011-08-16
US20120276540A1 (en) 2012-11-01
US20150072884A1 (en) 2015-03-12
US20150337391A1 (en) 2015-11-26
EP1035215A2 (de) 2000-09-13
JP2015015958A (ja) 2015-01-29
US20080032302A1 (en) 2008-02-07
JP5680502B2 (ja) 2015-03-04
EP1035215A3 (de) 2000-09-20
US7232655B2 (en) 2007-06-19
US20020160409A1 (en) 2002-10-31
US9790558B2 (en) 2017-10-17
ES2528180T3 (es) 2015-02-05
US9045802B2 (en) 2015-06-02
US6376188B1 (en) 2002-04-23
US20110177510A1 (en) 2011-07-21
US6174681B1 (en) 2001-01-16
JP2011224021A (ja) 2011-11-10
EP1650313B1 (de) 2014-11-05
JP6170024B2 (ja) 2017-07-26
DK1650313T3 (en) 2015-01-26
US8785129B2 (en) 2014-07-22
JP2000270900A (ja) 2000-10-03

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